Three-dimensional tissue culture models in cancer biology

Taking Cell-Matrix Adhesions to the Third Dimension

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How does the extracellular matrix direct gene expression?

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Carcinoma-associated fibroblasts stimulate tumor progression of initiated human epithelium

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Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

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Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction

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Teratocarcinomas and Mammalian Embryogenesis

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The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene

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Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology

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Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer.

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Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis.

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Three-dimensional cell cultures: from molecular mechanisms to clinical applications

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Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells.

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Bioabsorbable polymer scaffolds for tissue engineering capable of sustained growth factor delivery

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The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells.

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Optimized suspension culture: the rotating-wall vessel

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Know thy neighbor: stromal cells can contribute oncogenic signals

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Growing tissues in microgravity

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Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell propertiesPreprint

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In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse

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In vivo evaluation of poly(l-lactic acid) porous conduits for peripheral nerve regeneration

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Breast stroma plays a dominant regulatory role in breast epithelial growth and differentiation: implications for tumor development and progression.

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A biodegradable polymer as a cytokine delivery system for inducing bone formation

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Reduced shear stress: A major component in the ability of mammalian tissues to form three‐dimensional assemblies in simulated microgravity

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Evaluation of Nanostructured Composite Collagen–Chitosan Matrices for Tissue Engineering

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Immunohistochemical localization of integrins in the normal, hyperplastic, and neoplastic breast. Correlations with their functions as receptors and cell adhesion molecules.

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Use of extracellular matrix components for cell culture

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Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells

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Thrombospondin-1 Induces Endothelial Cell Apoptosis and Inhibits Angiogenesis by Activating the Caspase Death Pathway

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The Differentiated State of Normal and Malignant Cells or How to Define a “Normal” Cell in Culture

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Cellular growth and survival are mediated by β1 integrins in normal human breast epithelium but not in breast carcinoma

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Engineered Smooth Muscle Tissues: Regulating Cell Phenotype with the Scaffold

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In vitrodifferentiation of chick embryo bone marrow stromal cells into cartilaginous and bone‐like tissues

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Osteochondral Repair Using Perichondrial Cells: A 1-Year Study in Rabbits

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Effects of Thomsen-Friedenreich antigen-specific peptide P-30 on beta-galactoside-mediated homotypic aggregation and adhesion to the endothelium of MDA-MB-435 human breast carcinoma cells.

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A Heterologous 3-D Coculture Model of Breast Tumor Cells and Fibroblasts to Study Tumor-Associated Fibroblast Differentiation

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Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: suppression by mutant c-H-ras oncogene expression.

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Designer microenvironments for the analysis of cell and tissue function

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Dynamic reciprocity revisited: a continuous, bidirectional flow of information between cells and the extracellular matrix regulates mammary epithelial cell function

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Apoptosis and metastasis: a superior resistance of metastatic cancer cells to programmed cell death

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Intrauterine transplantation of rat basal cell carcinoma as a model for reconversion of malignant to benign growth.

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Mesenchyme-induced changes in the neoplastic characteristics of the Dunning prostatic adenocarcinoma.

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Insulin-like growth factor mediated stromal-epithelial interactions in human breast cancer

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Desmoplasia and its relevance to colorectal tumour invasion

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Strategy for the Selection of Scaffolds for Tissue Engineering

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Three-dimensional Growth and Differentiation of Ovarian Tumor Cell Line in High Aspect Rotating-wall Vessel: Morphologic and Embryologic Considerations

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Dynamics of a microcarrier particle in the simulated microgravity environment of a rotating-wall vessel.

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Blockade of Tumor Cell Transforming Growth Factor-βs Enhances Cell Cycle Progression and Sensitizes Human Breast Carcinoma Cells to Cytotoxic Chemotherapy

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Halfway between 2D and Animal Models: Are 3D Cultures the Ideal Tool to Study Cancer-Microenvironment Interactions?

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3D tumor models: History, advances and future perspectives

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Next-Generation Liver Medicine Using Organoid Models

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