Cited by 355

The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.

The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC)

Dawson, Christopher W., Port, Rebecca J., Young, Lawrence S.·2012·Seminars in Cancer Biology

DOI 10.1016/j.semcancer.2012.01.004

Open this paper in CoChat — free account

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.semcancer.2012.01.004

Cites

109 of 109 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Polyak, K., & Weinberg, R. A. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2620 · Cited by 3,302
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
Bergers, G., Brekken, R., McMahon, G., Vu, T. H., Itoh, T., Tamaki, K., Tanzawa, K., Thorpe, P., Itohara, S., Werb, Z., et al. (2000) · Nature Cell Biology · doi:10.1038/35036374 · Cited by 2,797
Epstein–Barr virus: 40 years on
Young, L. S., & Rickinson, A. B. (2004) · Nature Reviews Cancer · doi:10.1038/nrc1452 · Cited by 2,227
Self-citation
Epithelial-Mesenchymal Transitions
Kang, Y., & Massagué, J. (2004) · Cell · doi:10.1016/j.cell.2004.07.011 · Cited by 1,525
Clonal Proliferations of Cells Infected with Epstein–Barr Virus in Preinvasive Lesions Related to Nasopharyngeal Carcinoma
Pathmanathan, R., Prasad, U., Sadler, R., Flynn, K., & Raab-Traub, N. (1995) · New England Journal of Medicine · doi:10.1056/nejm199509143331103 · Cited by 620
IRF7: activation, regulation, modification and function
Ning, S., Pagano, J. S., & Barber, G. N. (2011) · Genes & Immunity · doi:10.1038/gene.2011.21 · Cited by 601
Epstein–Barr virus in the pathogenesis of NPC
Raab-Traub, N. (2002) · Seminars in Cancer Biology · doi:10.1016/s1044579x0200086x · Cited by 562
Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: coexpression of EBNA1, LMP1, and LMP2 transcripts
Brooks, L., Yao, Q. Y., Rickinson, A. B., & Young, L. S. (1992) · Journal of Virology · doi:10.1128/jvi.66.5.2689-2697.1992 · Cited by 480
Self-citation
p63 regulates an adhesion programme and cell survival in epithelial cells
Carroll, D. K., Carroll, J. S., Leong, C.-O., Cheng, F., Brown, M., Mills, A. A., Brugge, J. S., & Ellisen, L. W. (2006) · Nature Cell Biology · doi:10.1038/ncb1420 · Cited by 403
MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins
Sengupta, S., den Boon, J. A., Chen, I.-H., Newton, M. A., Stanhope, S. A., Cheng, Y.-J., Chen, C.-J., Hildesheim, A., Sugden, B., & Ahlquist, P. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801130105 · Cited by 398
The Epstein–Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-κB
Izumi, K. M., & Kieff, E. D. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.23.12592 · Cited by 394
Activation of the p38 Mitogen-activated Protein Kinase Pathway by Epstein-Barr Virus-encoded Latent Membrane Protein 1 Coregulates Interleukin-6 and Interleukin-8 Production
Eliopoulos, A. G., Gallagher, N. J., Blake, S. M. S., Dawson, C. W., & Young, L. S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.23.16085 · Cited by 354
Self-citation
Integral membrane protein 2 of Epstein—barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases
Miller, C. L., Burkhardt, A. L., Lee, J. H., Stealey, B., Longnecker, R., Bolen, J. B., & Kieff, E. (1995) · Immunity · doi:10.1016/s1074-7613(95)80040-9 · Cited by 320
Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade
Kieser, A. (1997) · The EMBO Journal · doi:10.1093/emboj/16.21.6478 · Cited by 319
miRNA control of tumor cell invasion and metastasis
Baranwal, S., & Alahari, S. K. (2010) · International Journal of Cancer · doi:10.1002/ijc.25014 · Cited by 316
The Epstein–Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases
Tsai, C.-N., Tsai, C.-L., Tse, K.-P., Chang, H.-Y., & Chang, Y.-S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.152059399 · Cited by 315
Nasopharyngeal carcinoma: molecular pathogenesis and therapeutic developments
Tao, Q., & Chan, A. T. C. (2007) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399407000312 · Cited by 312
Epstein-Barr Virus LMP2A Transforms Epithelial Cells, Inhibits Cell Differentiation, and Activates Akt
Scholle, F., Bendt, K. M., & Raab-Traub, N. (2000) · Journal of Virology · doi:10.1128/jvi.74.22.10681-10689.2000 · Cited by 277
MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma
Chen, H.-C., Chen, G.-H., Chen, Y.-H., Liao, W.-L., Liu, C.-Y., Chang, K.-P., Chang, Y.-S., & Chen, S.-J. (2009) · British Journal of Cancer · doi:10.1038/sj.bjc.6604948 · Cited by 276
Induction of cyclooxygenase-2 by Epstein–Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells
Murono, S., Inoue, H., Tanabe, T., Joab, I., Yoshizaki, T., Furukawa, M., & Pagano, J. S. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.121016998 · Cited by 272
Genetic and epigenetic changes in nasopharyngeal carcinoma
Lo, K.-W., & Huang, D. P. (2002) · Seminars in Cancer Biology · doi:10.1016/s1044579x02000883 · Cited by 269
Activation of the cJun N-terminal kinase (JNK) pathway by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1)
Eliopoulos, A. G., & Young, L. S. (1998) · Oncogene · doi:10.1038/sj.onc.1201694 · Cited by 268
Self-citation
An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking.
Miller, C. L., Lee, J. H., Kieff, E., & Longnecker, R. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.2.772 · Cited by 257
Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene
Fries, K. L., Miller, W. E., & Raab-Traub, N. (1996) · Journal of Virology · doi:10.1128/jvi.70.12.8653-8659.1996 · Cited by 255
Isolation and sequencing of the Epstein-Barr virus BNLF-1 gene (LMP1) from a Chinese nasopharyngeal carcinoma
Hu, L.-F., Zabarovsky, E. R., Chen, F., Cao, S.-L., Ernberg, I., Klein, G., & Winberg, G. (1991) · Journal of General Virology · doi:10.1099/0022-1317-72-10-2399 · Cited by 252
Expression of the BNLF-1 oncogene of Epstein-Barr virus in the skin of transgenic mice induces hyperplasia and aberrant expression of keratin 6
Wilson, J. B., Weinberg, W. C., Johnson, R., Yuspa, S. H., & Levine, A. J. (1990) · Cell · doi:10.1016/0092-8674(90)90695-b · Cited by 247
The Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor
Miller, W. E., Earp, H. S., & Raab-Traub, N. (1995) · Journal of Virology · doi:10.1128/jvi.69.7.4390-4398.1995 · Cited by 237
Interleukin-6 Inhibits Transforming Growth Factor-β-induced Apoptosis through the Phosphatidylinositol 3-Kinase/Akt and Signal Transducers and Activators of Transcription 3 Pathways
Chen, R.-H., Chang, M.-C., Su, Y.-H., Tsai, Y.-T., & Kuo, M.-L. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.33.23013 · Cited by 227
Twist and Epithelial-Mesenchymal Transition Are Induced by the EBV Oncoprotein Latent Membrane Protein 1 and Are Associated with Metastatic Nasopharyngeal Carcinoma
Horikawa, T., Yang, J., Kondo, S., Yoshizaki, T., Joab, I., Furukawa, M., & Pagano, J. S. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-3933 · Cited by 211
Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Activates the JNK Pathway through Its Extreme C Terminus via a Mechanism Involving TRADD and TRAF2
Eliopoulos, A. G., Blake, S. M. S., Floettmann, J. E., Rowe, M., & Young, L. S. (1999) · Journal of Virology · doi:10.1128/jvi.73.2.1023-1035.1999 · Cited by 206
Self-citation
The significance of LMP1 expression in nasopharyngeal carcinoma
Tsao, S. W., Tramoutanis, G., Dawson, C. W., Lo, A. K. F., & Huang, D. P. (2002) · Seminars in Cancer Biology · doi:10.1016/s1044579x02000901 · Cited by 204
Self-citation
Epstein-Barr Virus Latent Membrane Protein 1 Induces Synthesis of Hypoxia-Inducible Factor 1α
Wakisaka, N., Kondo, S., Yoshizaki, T., Murono, S., Furukawa, M., & Pagano, J. S. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.12.5223-5234.2004 · Cited by 204
Epstein-Barr Virus-Encoded LMP2A Induces an Epithelial–Mesenchymal Transition and Increases the Number of Side Population Stem-like Cancer Cells in Nasopharyngeal Carcinoma
Kong, Q.-L., Hu, L.-J., Cao, J.-Y., Huang, Y.-J., Xu, L.-H., Liang, Y., Xiong, D., Guan, S., Guo, B.-H., Mai, H.-Q., et al. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1000940 · Cited by 199
High level expression of ΔN-p63: a mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)?
Crook, T., Nicholls, J. M., Brooks, L., O'Nions, J., & Allday, M. J. (2000) · Oncogene · doi:10.1038/sj.onc.1203656 · Cited by 194
miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion
Xia, H., Ng, S. S., Jiang, S., Cheung, W. K. C., Sze, J., Bian, X.-W., Kung, H.-F., & Lin, M. C. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.11.093 · Cited by 193
A second Epstein-Barr virus membrane protein (LMP2) is expressed in latent infection and colocalizes with LMP1
Longnecker, R., & Kieff, E. (1990) · Journal of Virology · doi:10.1128/jvi.64.5.2319-2326.1990 · Cited by 178
Signature Amino Acid Changes in Latent Membrane Protein 1 Distinguish Epstein–Barr Virus Strains
Edwards, R. H., Seillier-Moiseiwitsch, F., & Raab-Traub, N. (1999) · Virology · doi:10.1006/viro.1999.9855 · Cited by 175
Latent Membrane Protein 2A of Epstein-Barr Virus Binds WW Domain E3 Protein-Ubiquitin Ligases That Ubiquitinate B-Cell Tyrosine Kinases
Winberg, G., Matskova, L., Chen, F., Plant, P., Rotin, D., Gish, G., Ingham, R., Ernberg, I., & Pawson, T. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.22.8526-8535.2000 · Cited by 173
Epstein–Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKKα-dependent noncanonical NF-κB activation
Luftig, M., Yasui, T., Soni, V., Kang, M.-S., Jacobson, N., Cahir-McFarland, E., Seed, B., & Kieff, E. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2237183100 · Cited by 167
Two related Epstein-Barr virus membrane proteins are encoded by separate genes
Sample, J., Liebowitz, D., & Kieff, E. (1989) · Journal of Virology · doi:10.1128/jvi.63.2.933-937.1989 · Cited by 161
Epstein–Barr Virus Coopts Lipid Rafts to Block the Signaling and Antigen Transport Functions of the BCR
Dykstra, M. L., Longnecker, R., & Pierce, S. K. (2001) · Immunity · doi:10.1016/s1074-7613(01)00089-9 · Cited by 161
Epstein-Barr Virus LMP1 Activates EGFR, STAT3, and ERK through Effects on PKCδ
Kung, C.-P., Meckes, D. G., & Raab‐Traub, N. (2011) · Journal of Virology · doi:10.1128/jvi.01703-10 · Cited by 157
The Epstein–Barr Virus Latent Membrane Protein 2A PY Motif Recruits WW Domain-Containing Ubiquitin-Protein Ligases
Ikeda, M., Ikeda, A., Longan, L. C., & Longnecker, R. (2000) · Virology · doi:10.1006/viro.1999.0166 · Cited by 147
The latent membrane protein 1 oncogene modifies B-cell physiology by regulating autophagy
Lee, D. Y., & Sugden, B. (2007) · Oncogene · doi:10.1038/sj.onc.1210946 · Cited by 146
Role of Epstein-Barr virus encoded latent membrane protein 1 in the carcinogenesis of nasopharyngeal carcinoma.
Zheng, H., Li, L. L., Hu, D. S., Deng, X., & Cao, Y. (2007) · PubMed · Cited by 144
Epstein–Barr virus latent membrane protein 1 CTAR1 mediates rodent and human fibroblast transformation through activation of PI3K
Mainou, B. A., Everly, D. N., & Raab‐Traub, N. (2005) · Oncogene · doi:10.1038/sj.onc.1208846 · Cited by 143
Epstein-barr virus latency: LMP2, a regulator or means for Epstein- barr virus persistence?
Longnecker, R. (2000) · Advances in cancer research · doi:10.1016/s0065-230x(00)79006-3 · Cited by 142
EBV Latent Membrane Protein 1 Up-regulates Hypoxia-Inducible Factor 1α through Siah1-Mediated Down-regulation of Prolyl Hydroxylases 1 and 3 in Nasopharyngeal Epithelial Cells
Kondo, S., Seo, S. Y., Yoshizaki, T., Wakisaka, N., Furukawa, M., Joab, I., Jang, K. L., & Pagano, J. S. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-1679 · Cited by 142
Epstein–Barr virus latent-infection membrane proteins are palmitoylated and raft-associated: Protein 1 binds to the cytoskeleton through TNF receptor cytoplasmic factors
Higuchi, M., Izumi, K. M., & Kieff, E. D. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.081075298 · Cited by 138
Alterations of the p53 gene in nasopharyngeal carcinoma
Effert, P. J., McCoy, R., Abdel‐Hamid, M., Flynn, K., Zhang, Q., Busson, P., Tursz, T., Liu, E., & Raab‐Traub, N. (1992) · Journal of Virology · doi:10.1128/jvi.66.6.3768-3775.1992 · Cited by 137
Association of latent membrane protein 1 and matrix metalloproteinase 9 with metastasis in nasopharyngeal carcinoma
Horikawa, T., Yoshizaki, T., Sheen, T., Lee, S.-Y., & Furukawa, M. (2000) · Cancer · Cited by 133
MicroRNA-10b induced by Epstein-Barr virus-encoded latent membrane protein-1 promotes the metastasis of human nasopharyngeal carcinoma cells
Li, G., Wu, Z., Peng, Y., Liu, X., Lü, J., Wang, L., Pan, Q., He, M.-L., & Li, X. (2010) · Cancer Letters · doi:10.1016/j.canlet.2010.07.021 · Cited by 123
Modulation of the Cell Growth Regulator mTOR by Epstein-Barr Virus-Encoded LMP2A
Moody, C. A., Scott, R. S., Amirghahari, N., Nathan, C. O., Young, L. S., Dawson, C., & Sixbey, J. W. (2005) · Journal of Virology · doi:10.1128/jvi.79.9.5499-5506.2005 · Cited by 123
Self-citation
Latent Membrane Protein 2A Inhibits Transforming Growth Factor-β1-Induced Apoptosis through the Phosphatidylinositol 3-Kinase/Akt Pathway
Fukuda, M., & Longnecker, R. (2004) · Journal of Virology · doi:10.1128/jvi.78.4.1697-1705.2004 · Cited by 121
LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2
Kieser, A., Kaiser, C., & Hammerschmidt, W. (1999) · The EMBO Journal · doi:10.1093/emboj/18.9.2511 · Cited by 119
Profile of cytokine expression in nasopharyngeal carcinomas: a distinct expression of interleukin 1 in tumor and CD4+ T cells.
Huang, Y., Sheen, T., Chen, C. L., Lu, J., Chang, Y., Chen, J. Y., & Tsai, C.-H. A. (1999) · PubMed · Cited by 116
Epstein-Barr Virus Latent Membrane Protein 2A Mediates Transformation through Constitutive Activation of the Ras/PI3-K/Akt Pathway
Fukuda, M., & Longnecker, R. (2007) · Journal of Virology · doi:10.1128/jvi.00537-07 · Cited by 112
Epstein–Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-κB2 to p52 via an IKKγ/NEMO-independent signalling pathway
Eliopoulos, A. G., Caamaño, J., Flavell, J. R., Reynolds, G. M., Murray, P. G., Poyet, J., & Young, L. S. (2003) · Oncogene · doi:10.1038/sj.onc.1207120 · Cited by 111
Self-citation
Epstein–Barr virus-encoded LMP2A regulates viral and cellular gene expression by modulation of the NF-κB transcription factor pathway
Stewart, S. E., Dawson, W. O., Takada, K., Curnow, J., Moody, C. A., Sixbey, J. W., & Young, L. S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402135101 · Cited by 107
Self-citation
Epstein-Barr virus LMP1 blocks p16INK4a–RB pathway by promoting nuclear export of E2F4/5
Ohtani, N., Brennan, P., Gaubatz, S., Sanij, E., Hertzog, P. J., Wolvetang, E. J., Ghysdael, J., Rowe, M., & Hara, E. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302085 · Cited by 107
Epstein-Barr Virus Latent Membrane Protein 1 Induces Cancer Stem/Progenitor-Like Cells in Nasopharyngeal Epithelial Cell Lines
Kondo, S., Wakisaka, N., Muramatsu, M., Zen, Y., Endo, K., Murono, S., Sugimoto, H., Yamaoka, S., Pagano, J. S., & Yoshizaki, T. (2011) · Journal of Virology · doi:10.1128/jvi.00188-11 · Cited by 107
The Psoriatic Transcriptome Closely Resembles That Induced by Interleukin-1 in Cultured Keratinocytes
Mee, J. B., Johnson, C. M., Morar, N., Burslem, F., & Groves, R. W. (2007) · American Journal Of Pathology · doi:10.2353/ajpath.2007.061067 · Cited by 106
Epstein-Barr-Virus-Encoded LMP2A Induces Primary Epithelial Cell Migration and Invasion: Possible Role in Nasopharyngeal Carcinoma Metastasis
Pegtel, D. M., Subramanian, A., Sheen, T., Tsai, C.-H. A., Golub, T. R., & Thorley‐Lawson, D. A. (2005) · Journal of Virology · doi:10.1128/jvi.79.24.15430-15442.2005 · Cited by 105
Upregulation of MiR-155 in Nasopharyngeal Carcinoma is Partly Driven by LMP1 and LMP2A and Downregulates a Negative Prognostic Marker JMJD1A
Du, Z.-M., Hu, L.-F., Wang, H., Yan, L., Zeng, Y., Shao, J., & Ernberg, I. T. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019137 · Cited by 104
Role of The Epstein–Barr Virus-Encoded Latent Membrane Protein-1, LMP1, in The Pathogenesis of Nasopharyngeal Carcinoma
Morris, M. A., Dawson, W. O., & Young, L. S. (2009) · Future Oncology · doi:10.2217/fon.09.53 · Cited by 98
Self-citation
Interferon Regulatory Factor 7 Regulates Expression of Epstein-Barr Virus Latent Membrane Protein 1: a Regulatory Circuit
Ning, S., Hahn, A. M., Huye, L. E., & Pagano, J. S. (2003) · Journal of Virology · doi:10.1128/jvi.77.17.9359-9368.2003 · Cited by 98
Roles of the ITAM and PY Motifs of Epstein-Barr Virus Latent Membrane Protein 2A in the Inhibition of Epithelial Cell Differentiation and Activation of β-Catenin Signaling
Morrison, J. A., & Raab‐Traub, N. (2005) · Journal of Virology · doi:10.1128/jvi.79.4.2375-2382.2005 · Cited by 97
Syk Tyrosine Kinase Mediates Epstein-Barr Virus Latent Membrane Protein 2A-induced Cell Migration in Epithelial Cells
Lu, J., Lin, W. H., Chen, S.-Y., Longnecker, R., Tsai, S.-C., Chen, C.-L., & Tsai, C.-H. A. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m507305200 · Cited by 93
Epstein-Barr Virus Latent Membrane Protein 1 Induces Expression of the Epidermal Growth Factor Receptor through Effects on Bcl-3 and STAT3
Kung, C.-P., & Raab‐Traub, N. (2008) · Journal of Virology · doi:10.1128/jvi.00125-08 · Cited by 93
Unique Signaling Properties of CTAR1 in LMP1-Mediated Transformation
Mainou, B. A., Everly, D. N., & Raab‐Traub, N. (2007) · Journal of Virology · doi:10.1128/jvi.01001-07 · Cited by 86
Interferon Regulatory Factor 7 Is Activated by a Viral Oncoprotein through RIP-Dependent Ubiquitination
Huye, L. E., Ning, S., Kelliher, M. A., & Pagano, J. S. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.02256-06 · Cited by 84
Expression of cytokine and chemokine genes in Epstein-Barr virus-associated nasopharyngeal carcinoma: comparison with Hodgkin's disease
Beck, A., P�zolt, D., Grabenbauer, G. G., Nicholls, J. M., Herbst, H., Young, L. S., & Niedobitek, G. (2001) · The Journal of Pathology · doi:10.1002/path.867 · Cited by 82
Self-citation
Decreased expression of E‐cadherin and increased invasive capacity in EBV‐LMP‐transfected human epithelial and murine adenocarcinoma cells
Fåhræus, R., Chen, W., Trivedi, P., Klein, G., & Öbrink, B. (1992) · International Journal of Cancer · doi:10.1002/ijc.2910520527 · Cited by 81
The Epstein-Barr Virus-Encoded LMP2A and LMP2B Proteins Promote Epithelial Cell Spreading and Motility
Allen, M. D., Young, L. S., & Dawson, W. O. (2005) · Journal of Virology · doi:10.1128/jvi.79.3.1789-1802.2005 · Cited by 77
Self-citation
The A20 Deubiquitinase Activity Negatively Regulates LMP1 Activation of IRF7
Ning, S., & Pagano, J. S. (2010) · Journal of Virology · doi:10.1128/jvi.00364-10 · Cited by 76
Intracellular Signaling Molecules Activated by Epstein-Barr Virus for Induction of Interferon Regulatory Factor 7
Zhang, L., Wu, L., Hong, K., & Pagano, J. S. (2001) · Journal of Virology · doi:10.1128/jvi.75.24.12393-12401.2001 · Cited by 75
The signaling pathways of Epstein-Barr virus-encoded latent membrane protein 2A (LMP2A) in latency and cancer
Pang, M.-F., Lin, K.-W., & Peh, S. (2008) · Cellular & Molecular Biology Letters · doi:10.2478/s11658-008-0045-2 · Cited by 74
Cholesterol is critical for Epstein-Barr virus latent membrane protein 2A trafficking and protein stability
Ikeda, M., & Longnecker, R. (2006) · Virology · doi:10.1016/j.virol.2006.10.046 · Cited by 72
LMP1 of Epstein–Barr virus suppresses cellular senescence associated with the inhibition of p16INK4a expression
Yang, X., He, Z., Xin, B., & Cao, L. (2000) · Oncogene · doi:10.1038/sj.onc.1203515 · Cited by 71
Epstein–Barr virus: LMP1 masquerades as an active receptor
Eliopoulos, A. G., & Rickinson, A. B. (1998) · Current Biology · doi:10.1016/s0960-9822(98)70123-x · Cited by 71
The Epstein-Barr Virus Latent Membrane Protein 1 and Transforming Growth Factor–β1 Synergistically Induce Epithelial–Mesenchymal Transition in Lung Epithelial Cells
Sides, M. D., Klingsberg, R. C., Shan, B., Gordon, K. A., Hồng, N. T., Lin, Z., Takahashi, T., Flemington, E. K., & Lasky, J. A. (2010) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2009-0232oc · Cited by 69
Epstein-Barr virus-containing epithelial cells from nasopharyngeal carcinoma produce interleukin 1 alpha.
Busson, P., Braham, K., Ganem, G., Thomas, F., Grausz, D., Lipinski, M., Wakasugi, H., & Tursz, T. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.17.6262 · Cited by 69
Epithelial Cell Adhesion to Extracellular Matrix Proteins Induces Tyrosine Phosphorylation of the Epstein-Barr Virus Latent Membrane Protein 2: a Role for C-Terminal Src Kinase
Scholle, F., Longnecker, R., & Raab‐Traub, N. (1999) · Journal of Virology · doi:10.1128/jvi.73.6.4767-4775.1999 · Cited by 63
RECK is a target of Epstein–Barr virus latent membrane protein 1
Liu, L., Peng, J., Chang, H., & Hung, W. (2003) · Oncogene · doi:10.1038/sj.onc.1207157 · Cited by 62
Induction of Epidermal Growth Factor Receptor Expression by Epstein-Barr Virus Latent Membrane Protein 1 C-Terminal-Activating Region 1 Is Mediated by NF-κB p50 Homodimer/Bcl-3 Complexes
Thornburg, N. J., & Raab‐Traub, N. (2007) · Journal of Virology · doi:10.1128/jvi.01601-07 · Cited by 60
Latent membrane protein 1 of Epstein-Barr virus regulates p53 phosphorylation through MAP kinases
Li, L., Guo, L., Tao, Y., Zhou, S., Wang, Z., Luo, W., Hu, D., Li, Z., Xiao, L., Tang, M., et al. (2007) · Cancer Letters · doi:10.1016/j.canlet.2007.04.014 · Cited by 58
Promotion of metastasis in nasopharyngeal carcinoma by Epstein-Barr virus latent membrane protein-1.
Yoshizaki, T. (2002) · PubMed · doi:10.14670/hh-17.845 · Cited by 58
Epstein-Barr Virus Latent Membrane Protein 1 Modulates Distinctive NF-κB Pathways through C-Terminus-Activating Region 1 To Regulate Epidermal Growth Factor Receptor Expression
Kung, C.-P., & Raab‐Traub, N. (2010) · Journal of Virology · doi:10.1128/jvi.00344-10 · Cited by 54
Epstein-Barr virus induces invasion and metastasis factors.
Wakisaka, N., & Pagano, J. S. (2003) · PubMed · Cited by 53
Itchy, a Nedd4 Ubiquitin Ligase, Downregulates Latent Membrane Protein 2A Activity in B-Cell Signaling
Ikeda, A., Caldwell, R. G., Longnecker, R., & Ikeda, M. (2003) · Journal of Virology · doi:10.1128/jvi.77.9.5529-5534.2003 · Cited by 53
MUC1 Induced by Epstein-Barr Virus Latent Membrane Protein 1 Causes Dissociation of the Cell-Matrix Interaction and Cellular Invasiveness via STAT Signaling
Kondo, S., Yoshizaki, T., Wakisaka, N., Horikawa, T., Murono, S., Jang, K. L., Joab, I., Furukawa, M., & Pagano, J. S. (2006) · Journal of Virology · doi:10.1128/jvi.02222-06 · Cited by 50
BS69, a Specific Adaptor in the Latent Membrane Protein 1-Mediated c-Jun N-Terminal Kinase Pathway
Wan, J., Zhang, W. D., Wu, L., Bai, T., Zhang, M., Lo, K. W., Chui, Y., Cui, Y., Tao, Q., Yamamoto, M., et al. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.26.2.448-456.2006 · Cited by 47
Selection Pressure-Driven Evolution of the Epstein-Barr Virus-Encoded Oncogene LMP1 in Virus Isolates from Southeast Asia
Burrows, J. M., Bromham, L. D., Woolfit, M., Piganeau, G., Tellam, J., Connolly, G., Webb, N., Poulsen, L. M., Cooper, L. T., Burrows, S. R., et al. (2004) · Journal of Virology · doi:10.1128/jvi.78.13.7131-7137.2004 · Cited by 47
Induction of Receptor for Advanced Glycation End Products by EBV Latent Membrane Protein 1 and Its Correlation with Angiogenesis and Cervical Lymph Node Metastasis in Nasopharyngeal Carcinoma
Tsuji, A., Wakisaka, N., Kondo, S., Murono, S., Furukawa, M., & Yoshizaki, T. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-0198 · Cited by 46
Epstein-Barr Virus Latent Membrane Protein-1 Effects on Junctional Plakoglobin and Induction of a Cadherin Switch
Shair, K. H. Y., Schnegg, C. I., & Raab‐Traub, N. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-0468 · Cited by 46
Interleukins, laminin and epstein - barr virus latent membrane protein 1 (EBV LMP1) Promote metastatic phenotype in nasopharyngeal carcinoma
Chew, M. M., Gan, S. Y., Khoo, A. S. B., & Tan, E. (2010) · BMC Cancer · doi:10.1186/1471-2407-10-574 · Cited by 42
Epstein–Barr virus latent membrane protein 1 mediates phosphorylation and nuclear translocation of annexin A2 by activating PKC pathway
Yan, G., Luo, W., Lu, Z., Luo, X., Li, L., Liu, S., Liu, Y., Tang, M., Dong, Z., & Cao, Y. (2006) · Cellular Signalling · doi:10.1016/j.cellsig.2006.07.019 · Cited by 41
LMP1 of Epstein-Barr Virus Induces Proliferation of Primary Mouse Embryonic Fibroblasts and Cooperatively Transforms the Cells with a p16-Insensitive CDK4 Oncogene
Yang, X., Sham, J. S. T., Ng, M. H., Tsao, S., Zhang, D., Lowe, S. W., & Cao, L. (2000) · Journal of Virology · doi:10.1128/jvi.74.2.883-891.2000 · Cited by 38
Epstein–Barr virus-encoded LMP1 induces a hyperproliferative and inflammatory gene expression programme in cultured keratinocytes
Morris, M. A., Dawson, W. O., Wei, W., O’Neil, J. D., Stewart, S. E., Jia, J., Bell, A. I., Young, L. S., & Arrand, J. R. (2008) · Journal of General Virology · doi:10.1099/vir.0.2008/003970-0 · Cited by 37
Self-citation
STAP-2 Negatively Regulates both Canonical and Noncanonical NF-κB Activation Induced by Epstein-Barr Virus-Derived Latent Membrane Protein 1
Ikeda, O., Sekine, Y., Yasui, T., Oritani, K., Sugiyma, K., Muromoto, R., Ohbayashi, N., Yoshimura, A., & Matsuda, T. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00194-08 · Cited by 36
MDM2 expression in EBV-infected nasopharyngeal carcinoma cells
Wu, H., Lu, T., Lee, J.-J., Hwang, J.-K., Lin, Y., Wang, C.-K., & Lin, C. (2004) · Laboratory Investigation · doi:10.1038/labinvest.3700183 · Cited by 34
The LMP2A signalosome - a therapeutic target for Epstein-Barr virus latency and associated disease
Portis, T. (2002) · Frontiers in bioscience · doi:10.2741/portis · Cited by 29
DNA tumour viruses promote tumour cell invasion and metastasis by deregulating the normal processes of cell adhesion and motility
Morris, M. A., Young, L. S., & Dawson, W. O. (2008) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2008.03.005 · Cited by 21
Self-citation
Negative Regulation of Epstein-Barr Virus Latent Membrane Protein 1-mediated Functions by the Bone Morphogenetic Protein Receptor IA-binding Protein, BRAM1
Chung, P., Chang, Y., Liang, C.-L., & Meng, C. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206736200 · Cited by 20
BS69 cooperates with TRAF3 in the regulation of Epstein–Barr virus‐derived LMP1/CTAR1‐induced NF‐κB activation
Ikeda, O., Miyasaka, Y., Yoshida, R., Mizushima, A., Oritani, K., Sekine, Y., Kuroda, M., Yasui, T., Fujimuro, M., Muromoto, R., et al. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.01.060 · Cited by 17
The latent membrane protein 1 of Epstein-Barr virus and loss of the INK4a locus: paradoxes resolve to cooperation in carcinogenesis in vivo
MacDiarmid, J. A., Stevenson, D., Campbell, D. H., & Wilson, J. B. (2003) · Carcinogenesis · doi:10.1093/carcin/bgg070 · Cited by 17
Transcriptional repression of tissue inhibitor of metalloproteinase-3 by Epstein-Barr virus latent membrane protein 1 enhances invasiveness of nasopharyngeal carcinoma cells
Chang, S.-H., Chang, H., & Hung, W. (2008) · Oral Oncology · doi:10.1016/j.oraloncology.2007.11.005 · Cited by 16
Expression of Epstein-Barr Virus Latent Membrane Proteins Leads to Changes in Keratinocyte Cell Adhesion
Farwell, D. G., McDougall, J. K., & Coltrera, M. D. (1999) · Annals of Otology Rhinology & Laryngology · doi:10.1177/000348949910800906 · Cited by 16
[Cross-talk between c-Jun/Ets1 involved in EB virus-encoded latent membrane protein 1 regulates expression of matrix metalloproteinase-9 in nasopharyngeal carcinoma].
Zeng, L., Liu, Y. P., Tao, Y. G., et al. (2005) · PubMed · Cited by 7

Epstein–Barr virus infection and nasopharyngeal carcinoma
Tsao, S. W., Tsang, C. M., & Lo, K. W. (2017) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2016.0270 · Cited by 606
EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy
Fang, W., Zhang, J., Hong, S., Zhan, J., Chen, N., Qin, T., Tang, Y., Zhang, Y., Kang, S., Zhou, T., et al. (2014) · Oncotarget · doi:10.18632/oncotarget.2608 · Cited by 398
Epstein-Barr virus and nasopharyngeal carcinoma
Young, L. S., & Dawson, C. W. (2014) · Chinese Journal of Cancer · doi:10.5732/cjc.014.10197 · Cited by 253
Self-citation
RETRACTED ARTICLE: Vasculogenic mimicry formation in EBV-associated epithelial malignancies
Xiang, T., Lin, Y.-X., Ma, W., Zhang, H.-J., Chen, K.-M., He, G.-P., Zhang, X., Xu, M., Feng, Q.-S., Chen, M.-Y., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-07308-5 · Cited by 172
Retracted

See all 355

Authors: Dawson, C. W., Port, R. J., & Young, L. S.
Venue: Seminars in Cancer Biology
Publisher: Elsevier BV
Published: 2012-04
Volume: 22
Issue: 2
Pages: 144-153
ISSN: 1044-579X (ISSN-L)
DOI: 10.1016/j.semcancer.2012.01.004
OpenAlex: W2089732642
Cited by: 355
References: 109
FWCI: 12.78
Type: journal article
Language: en
Open access: closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.

The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC)

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cites

Cited by

Metadata

Record

About these checks

Data sources