The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Hypersomnia across mood disorders: A review and synthesis
Abstract
Hypersomnia is prevalent and persistent across mood disorders. This review has two aims: (1) to synthesize the research that has accrued on hypersomnia in mood disorders and (2) to identify an agenda for future research that advances knowledge on this critical, but understudied, feature of mood disorders. We begin by reviewing the state-of-the-science on the diagnosis, epidemiology and course of hypersomnia in Major Depressive Disorder, Bipolar Disorder, Dysthymic Disorder, and Seasonal Affective Disorder. We then address key measurement and assessment issues, particularly those arising from the use of objective methods. This section identifies a need to explore whether hypersomnia is a disorder of Time in Bed (TIB) rather than a disorder of Total Sleep Time (TST), or whether presentations of TIB vs. TST represent two subtypes of hypersomnia with differing etiologies. Established and proposed mechanisms contributing to hypersomnia are then highlighted, including the possibility that hypersomnia is an important mechanism contributing to the maintenance of mood disorder symptoms. We then move on to review the small body of literature on pharmacological interventions for hypersomnia in mood disorders. Though non-pharmacological treatments targeting hypersomnia have not yet been developed, we offer initial guidelines for such treatments and conclude with an agenda for future research.
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In bipolar disorder, insomnia is present during a depressive episode in 60% of patients.
“When it comes to bipolar disorder, insomnia is present during a depressive episode in 60% of patients”
From Effects of Antidepressants on Sleep (2017) · cites this paper as [12]
In bipolar disorder, 20-30% of patients suffer from prolonged sleep (hypersomnia) and increased daytime sleepiness.
“while 20 -30% suffer from prolonged sleep (hypersomnia) and increased daytime sleepiness [11, 12].”
From Effects of Antidepressants on Sleep (2017) · cites this paper as [12]
Insomnia complaints are present in 60-90% of patients with major depression, depending on episode severity.
“The complaints of insomnia are present in 60 -90%ofpatients with major depression, depending on the episode ' s severity.”
From Effects of Antidepressants on Sleep (2017) · cites this paper as [12]
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Metadata
- Authors
- Kaplan, K. A., & Harvey, A. G.
- Affiliations
- University of California, Berkeley (US)
- Corresponding author
- Harvey, Allison G.
- Venue
- Sleep Medicine Reviews
- Publisher
- Elsevier BV
- Published
- 2009-08
- Volume
- 13
- Issue
- 4
- Pages
- 275-285
- ISSN
- 1087-0792 (ISSN-L)
- OpenAlex
- W2077819245
- Cited by
- 249
- References
- 12
- Citations by year
- 2026: 10 · 2025: 16 · 2024: 19 · 2023: 12 · 2022: 15 · 2021: 22 · 2020: 15 · 2019: 18 · 2018: 7 · 2017: 15 · 2016: 15 · 2015: 14 · 2014: 17 · 2013: 17 · 2012: 11
- FWCI
- 1.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Sleep Medicine Reviews (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (R34MH080958)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
- Keywords
- hypersomnia, mood disorders, major depressive disorder, bipolar disorder, dysthymia, seasonal affective disorder, time in bed, total sleep time, non-pharmacological treatment
- MeSH terms
- Bipolar Disorder, Cross-Sectional Studies, Major Depressive Disorder, Humans, Disorders of Excessive Somnolence, Surveys and Questionnaires, Comorbidity, Seasonal Affective Disorder, Dysthymic Disorder, Mood Disorders, Diagnostic and Statistical Manual of Mental Disorders
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