Neuroscience-driven discovery and development of sleep therapeutics

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A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects

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Stress and the brain: from adaptation to disease

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Two-Process Model of Sleep Regulation

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The memory function of sleep

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Reactivation of hippocampal ensemble memories during sleep

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Narcolepsy in orexin Knockout Mice

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Hypothalamic regulation of sleep and circadian rhythms

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Insomnia as a predictor of depression: A meta-analytic evaluation of longitudinal epidemiological studies

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The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

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International Classification of Sleep Disorders

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Ghrelin enhances appetite and increases food intake in humans

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Regularly Occurring Periods of Eye Motility, and Concomitant Phenomena, During Sleep

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A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

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Reduced Number of Hypocretin Neurons in Human Narcolepsy

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Local sleep and learning

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Hypocretin (orexin) deficiency in human narcolepsy

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Extinction Learning in Humans

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Coordinated memory replay in the visual cortex and hippocampus during sleep

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The sleep switch: hypothalamic control of sleep and wakefulness

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Ontogenetic Development of the Human Sleep-Dream Cycle: The prime role of "dreaming sleep" in early life may be in the development of the central nervous system.

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Short Sleep Duration and Weight Gain: A Systematic Review

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Sleep Homeostasis and Models of Sleep Regulation

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Insomnia: Definition, Prevalence, Etiology, and Consequences

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Sleep and Psychiatric Disorders: A Meta-analysis

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Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress

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Effects of sleep deprivation on cognition

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Sleep state switching

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Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy, Hypophagia, and Obesity

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Neurocircuitry Models of Posttraumatic Stress Disorder and Extinction: Human Neuroimaging Research—Past, Present, and Future

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Efficient Recombination in Diverse Tissues by a Tamoxifen-Inducible Form of Cre: A Tool for Temporally Regulated Gene Activation/Inactivation in the Mouse

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Neural substrates of awakening probed with optogenetic control of hypocretin neurons

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Neurobiological Basis of Failure to Recall Extinction Memory in Posttraumatic Stress Disorder

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Neuroactive steroids

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Practice with Sleep Makes Perfect

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Correlates of Sleep and Waking in Drosophila melanogaster

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Sex Differences in Insomnia: A Meta-Analysis

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Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study

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Sleep Cycle Oscillation: Reciprocal Discharge by Two Brainstem Neuronal Groups

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Sleep and synaptic homeostasis: a hypothesis

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Epidemiology of insomnia: Prevalence, self-help treatments, consultations, and determinants of help-seeking behaviors

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Odor cues during slow-wave sleep prompt declarative memory consolidation

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Functional neuroanatomy of human rapid-eye-movement sleep and dreaming

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Chronic Behavioral Disorders of Human REM Sleep: A New Category of Parasomnia

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A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II

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Cytokines for psychologists: Implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition.

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The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias

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Overnight therapy? The role of sleep in emotional brain processing

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The epidemiology of major depressive episodes: results from the International Consortium of Psychiatric Epidemiology (ICPE) Surveys

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Rest in Drosophila is a sleep-like state

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Effects of early and late nocturnal sleep on declarative and procedural memory

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Sleep deprivation: effect on sleep stages and EEG power density in man

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Sleep inspires insight

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Cytokine-induced sickness behaviour: mechanisms and implications

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Plastic Synaptic Networks of the Amygdala for the Acquisition, Expression, and Extinction of Conditioned Fear

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Elevation of Plasma Cytokines in Disorders of Excessive Daytime Sleepiness: Role of Sleep Disturbance and Obesity

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Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease

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The Neurobiology of Sleep: Genetics, cellular physiology and subcortical networks

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Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

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Regional Slow Waves and Spindles in Human Sleep

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Local sleep in awake rats

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Inducible gene targeting in mice using the Cre/lox system.

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Effects of poor and short sleep on glucose metabolism and obesity risk

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Sleep in Normal Aging and Dementia

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The cognitive neuroscience of sleep: neuronal systems, consciousness and learning

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Practice Parameters for the Psychological and Behavioral Treatment of Insomnia: An Update. An American Academy of Sleep Medicine Report

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Restoration of brain energy metabolism as the function of sleep

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The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine

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Cytokines and the Brain: Implications for Clinical Psychiatry

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The content analysis of dreams

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Three-Dimensional Reconstruction of Brain-wide Wiring Networks in Drosophila at Single-Cell Resolution

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Insomnia and daytime cognitive performance: A meta-analysis

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Obliviscence during sleep and waking

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Cortical firing and sleep homeostasis

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Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes

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Cytokine-induced sickness behavior

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Preplay of future place cell sequences by hippocampal cellular assemblies

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“Scaffold-Hopping” by Topological Pharmacophore Search: A Contribution to Virtual Screening

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Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990–2010: a systematic review and analysis

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How (and why) the immune system makes us sleep

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Resilient Machines Through Continuous Self-Modeling

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Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions

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The reinterpretation of dreams: An evolutionary hypothesis of the function of dreaming

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The contribution of sleep to hippocampus-dependent memory consolidation

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Neuronal excitability modulation over the sleep cycle: a structural and mathematical model

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Distinct Narcolepsy Syndromes in Orexin Receptor-2 and Orexin Null Mice

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REM sleep behavior disorder

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A Genetic Risk Factor for Periodic Limb Movements in Sleep

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Melatonin as a chronobiotic

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Extensive and divergent effects of sleep and wakefulness on brain gene expression

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REM sleep and dreaming: towards a theory of protoconsciousness

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Light sleep versus slow wave sleep in memory consolidation: a question of global versus local processes?

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Neural correlates of insight in dreaming and psychosis

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Glucocorticoid receptors in the locus coeruleus mediate sleep disorders caused by repeated corticosterone treatment

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Closed-loop auditory stimulation of sleep slow oscillations: Basic principles and best practices

Esfahani, M. J., Farboud, S., Ngo, H.-V. V., Schneider, J., Weber, F. D., Talamini, L. M., & Dresler, M. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105379 · Cited by 65 · see citing works

Increased lucid dreaming frequency in narcolepsy

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Heterozygosity for the mood disorder-associated variant Gln460Arg alters P2X7 receptor function and sleep quality

Metzger, M. W., Walser, S. M., Dedic, N., Aprile-Garcia, F., Jakubcakova, V., Adamczyk, M., Webb, K. J., Uhr, M., Refojo, D., Schmidt, M. V., et al. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.3487-16.2017 · Cited by 59 · see citing works

Sleep Pharmacogenetics: Personalized Sleep-Wake Therapy

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Individual slow-wave morphology is a marker of aging

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Age-related changes in sleep EEG are attenuated in highly intelligent individuals

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Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 receptor antagonism

Leiser, S. C., Iglesias-Bregna, D., Westrich, L., Pehrson, A. L., & Sánchez, C. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881115592347 · Cited by 27 · see citing works

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Inflammation Is an Important Covariate for the Crosstalk of Sleep and the HPA Axis in Rheumatoid Arthritis

Straub, R. H., Detert, J., Dziurla, R., Fietze, I., Loeschmann, P.-A., Burmester, G. R., & Buttgereit, F. (2017) · NeuroImmunoModulation · doi:10.1159/000475714 · Cited by 25 · see citing works

Pharmacotherapy for restless legs syndrome

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Optimizing the methodology of human sleep and memory research

Németh, D., Gerbier, É., Jan Born, A., Rickard, T. C., Diekelmann, S., Fogel, S. M., Genzel, L., Prehn‐Kristensen, A., Payne, J. D., Dresler, M., et al. (2023) · Nature Reviews Psychology · doi:10.1038/s44159-023-00262-0 · Cited by 24 · see citing works

The influence of oxytocin-based interventions on sleep-wake and sleep-related behaviour and neurobiology: A systematic review of preclinical and clinical studies

Raymond, J. S., Rehn, S., Hoyos, C. M., & Bowen, M. T. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.10.016 · Cited by 21 · see citing works

Cordance derived from REM sleep EEG as a biomarker for treatment response in depression – a naturalistic study after antidepressant medication

Adamczyk, M., Gazea, M., Wollweber, B., Holsboer, F., Dresler, M., Steiger, A., & Pawlowski, M. A. (2015) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.02.007 · Cited by 20 · see citing works

Multi-feature fusion and improved BO and IGWO metaheuristics based models for automatically diagnosing the sleep disorders from sleep sounds

Akyol, S., Yıldırım, M., & Alataş, B. (2023) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2023.106768 · Cited by 19 · see citing works

Corticotropin-releasing hormone induces depression-like changes of sleep electroencephalogram in healthy women

SCHÜSSLER, P., Kluge, M., Gamringer, W., Wetter, T. C., Yassouridis, A., Uhr, M., Rupprecht, R., & Steiger, A. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.09.015 · Cited by 18 · see citing works

An fMRI Study of the Effects of Vibroacoustic Stimulation on Functional Connectivity in Patients with Insomnia

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Clinical and Experimental Human Sleep-Wake Pharmacogenetics

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Sleep neuroimaging: Review and future directions

Pereira, M., Chen, X., Paltarzhytskaya, A., Pacheсo, Y., Muller, N., Bovy, L., Lei, X., Chen, W., Ren, H., Song, C., et al. (2025) · Journal of Sleep Research · doi:10.1111/jsr.14462 · Cited by 12 · see citing works

A Transformer-Based Spatial-Temporal Sleep Staging Model Through Raw EEG

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Sustained polyphasic sleep restriction abolishes human growth hormone release

Rosenblum, Y., Weber, F. D., Rak, M., Zavecz, Z., Kunath, N., Breitenstein, B., Rasch, B., Zeising, M., Uhr, M., Steiger, A., et al. (2023) · SLEEP · doi:10.1093/sleep/zsad321 · Cited by 11 · see citing works

Cognitive Behavioral Therapy for Sleep in Cancer Patients: Research, Techniques, and Individual Considerations

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“When I Sleep Poorly, It Impacts Everything”: An Exploratory Qualitative Investigation of Stress and Sleep in Junior Endurance Athletes

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Lucid Dreaming

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Good Sleep as an Important Pillar for a Healthy Life

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Medikamente zur Behandlung von Schlafstörungen

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Functional connectome gradient predicts clinical symptoms of chronic insomnia disorder

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Chronic Insomnia, Pharmacotherapy and the Cognitive Behavioral Approaches

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Brain Structural Abnormalities in Posttraumatic Stress Disorder and Relations with Sleeping Problems

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Personalized Therapy of Neurological Disorders

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Restoring Serotonergic Homeostasis in the Lateral Hypothalamus Rescues Sleep Disturbances Induced by Early-Life Obesity

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Pharmakotherapie von Schlaf-Wach-Störungen

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Pitfalls in Sleep and Memory Research and How to Avoid Them: A Consensus PaperPreprint

Németh, D., Gerbier, É., Jan Born, A., Rickard, T. C., Albouy, G., Diekelmann, S., Fogel, S. M., Genzel, L., Prehn‐Kristensen, A., Payne, J. D., et al. (2021) · Preprints.org · doi:10.20944/preprints201908.0208.v2 · Cited by 4 · see citing works

Optimizing Methodology of Sleep and Memory Research in HumansPreprint

Németh, D., Gerbier, É., Jan Born, A., Rickard, T. C., Diekelmann, S., Fogel, S. M., Genzel, L., Prehn‐Kristensen, A., Payne, J. D., Dresler, M., et al. (2023) · Preprints.org · doi:10.20944/preprints201908.0208.v4 · Cited by 2 · see citing works

Efficient Frequent Chronicle Mining Algorithms: Application to Sleep Disorder

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Medikamente zur Behandlung von Schlafstörungen

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Origin of Typical Disease Sequelae

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The Multifunctionality of Dreaming and the Oblivious Avatar

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Kreativität und Schlaf

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Management of Nonmotor Symptoms of Parkinson's Disease

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Medikamente zur Behandlung von Schlafstörungen

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Medikamente zur Behandlung von Schlafstörungen

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Medikamente zur Behandlung von Schlafstörungen

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Bedtime Brain State Predicts the Impact of Closed-Loop Auditory Stimulation on Sleep and CognitionPreprint

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Chronic Insomnia, Pharmacotherapy and the Cognitive Behavioral

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Welche Medikamente gegen Insomnie einsetzen?

Steiger, A. (2021) · DNP - Der Neurologe und Psychiater · doi:10.1007/s15202-021-4745-z

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