Prostaglandin D2 and sleep/wake regulation

Hypothalamic regulation of sleep and circadian rhythms

Saper, C. B., Scammell, T. E., & Lu, J. (2005) · Nature · doi:10.1038/nature04284 · Cited by 2,804

Sleep state switching

Saper, C. B., Fuller, P. M., Pedersen, N. P., Lu, J., & Scammell, T. E. (2010) · Neuron · doi:10.1016/j.neuron.2010.11.032 · Cited by 1,404

Adenosine: A Mediator of the Sleep-Inducing Effects of Prolonged Wakefulness

Porkka-Heiskanen, T., Strecker, R. E., Thakkar, M., Bjørkum, A. A., Greene, R. W., & McCarley, R. W. (1997) · Science · doi:10.1126/science.276.5316.1265 · Cited by 1,252

Activation of ventrolateral preoptic neurons during sleep

Sherin, J. E., Shiromani, P. J., McCarley, R. W., & Saper, C. B. (1996) · Science · doi:10.1126/science.271.5246.216 · Cited by 1,111

Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2

Hirai, H., Tanaka, K., Yoshie, O., Ogawa, K., Kenmotsu, K., Takamori, Y., Ichimasa, M., Sugamura, K., Nakamura, M., Takano, S., et al. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.193.2.255 · Cited by 1,101

Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine

Huang, Z.-L., Qu, W.-M., Eguchi, N., Chen, J.-F., Schwarzschild, M. A., Fredholm, B. B., Urade, Y., & Hayaishi, O. (2005) · Nature Neuroscience · doi:10.1038/nn1491 · Cited by 640

Sleep as a fundamental property of neuronal assemblies

Krueger, J. M., Rector, D. M., Roy, S., Van Dongen, H. P. A., Belenky, G., & Panksepp, J. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2521 · Cited by 596

Arousal effect of orexin A depends on activation of the histaminergic system

Huang, Z., Qu, W., Li, W., Mochizuki, T., Eguchi, N., Watanabe, T., Urade, Y., & Hayaishi, O. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.181330998 · Cited by 555

Neurobiology of REM and NREM sleep

McCarley, R. W. (2007) · Sleep Medicine · doi:10.1016/j.sleep.2007.03.005 · Cited by 538

Increased production of prostaglandin D2 in patients with systemic mastocytosis

Roberts, L. J., Sweetman, B. J., Lewis, R. A., Austen, K. F., & Oates, J. A. (1980) · New England Journal of Medicine · doi:10.1056/nejm198012113032405 · Cited by 423

GPR39 Deficiency Impairs Memory and Alters Oxylipins and Inflammatory Cytokines Without Affecting Cerebral Blood Flow in a High-Fat Diet Mouse Model of Cognitive Impairment

Bah, T. M., Allen, E. M., García‐Jaramillo, M., Perez, R., Zarnegarnia, Y., Davis, C. M., Bloom, M. B., Magaña, A. A., Choi, J., Bobe, G., et al. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.893030 · Cited by 11

Lipocalin-type prostaglandin D synthase levels increase in patients with narcolepsy and idiopathic hypersomnia

Wang, P., Li, Q., Dong, X., An, H., Li, J., Zhao, L., Yan, H., Aritake, K., Huang, Z., Strohl, K. P., et al. (2020) · SLEEP · doi:10.1093/sleep/zsaa234 · Cited by 12

The Role of Prostaglandins as Major Inflammatory Mediators in Colorectal Cancer

Macia-Guardado, M., Lutz, V., Hengstschläger, M., & Dolznig, H. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262412191 · Cited by 17

Computer-Aided Designing Peptide Inhibitors of Human Hematopoietic Prostaglandin D2 Synthase Combined Molecular Docking and Molecular Dynamics Simulation

Cui, J., Feng, Y., Yang, T., Wang, X., & Tang, H. L. (2023) · Molecules · doi:10.3390/molecules28155933 · Cited by 11

Plasma prostaglandin D2 synthase levels in sleep and neurological diseases

Suzuki, K., Suzuki, S., Ishii, Y., Okamura, M., Matsubara, T., Fujita, H., Nozawa, N., Kobayashi, S., & Hirata, K. (2020) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.116692 · Cited by 12

Natural-Derived COX-2 Inhibitors as Anticancer Drugs: A Review of their Structural Diversity and Mechanism of Action

Zarghi, A., Mahboubi‐Rabbani, M., & Abbasi, M. (2022) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1389450123666220516153915 · Cited by 11

Effects of commonly used analgesics on sleep architecture: a topical review

Antila, H., Lilius, T. O., Palada, V., Lohela, T. J., Bell, R. F., Porkka‐Heiskanen, T., & Kalso, E. A. (2024) · Pain · doi:10.1097/j.pain.0000000000003201 · Cited by 14

Astrocyte atrophy induced by L-PGDS/PGD2/Src signaling dysfunction in the central amygdala mediates postpartum depression

Sheng, Z., Liu, Q., Song, Y., Ye, B., Li, Y., Song, Y., Liu, J., Zhang, B., Guo, F., Xu, Z., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.05.083 · Cited by 10

Non-esterified erythrocyte linoleic acid, arachidonic acid, and subjective sleep outcomes

Sanders, A. E., Wallace, E. D., Ehrmann, B. M., Soma, P. S., Shaikh, S. R., Preisser, J. S., Ohrbach, R. K., Fillingim, R. B., & Slade, G. D. (2023) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2023.102580 · Cited by 10

A perfect storm: sleep loss causes systemic inflammation and death

Nguyen, A. D., Costa, P. C., & Raizen, D. M. (2024) · Cell Research · doi:10.1038/s41422-023-00924-x · Cited by 11

A role for prostaglandins in rapid cycling suggested by episode‐specific gene expression shifts in peripheral blood mononuclear cells: a preliminary report

Gurvich, A., Begemann, M., Dahm, L., Sargin, D., Miskowiak, K. W., & Ehrenreich, H. (2014) · Bipolar Disorders · doi:10.1111/bdi.12223 · Cited by 10

Prostaglandin D2in the regulation of sleep

Urade, Y., & Lazarus, M. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139649469.010 · Cited by 10

Sleep and inflammation: a bidirectional relationship

Engert, L. C., & Besedovsky, L. (2025) · Somnologie - Schlafforschung und Schlafmedizin · doi:10.1007/s11818-025-00495-6 · Cited by 18

Association between idiopathic hypersomnia and a genetic variant in the PER3 gene

Chérasse, Y., Taira, Y., Rassu, A. L., Barateau, L., Evangelista, E., Muratani, M., Funato, H., Yanagisawa, M., & Dauvilliers, Y. A. (2024) · Journal of Sleep Research · doi:10.1111/jsr.14146 · Cited by 9

Central Neural Circuits Orchestrating Thermogenesis, Sleep-Wakefulness States and General Anesthesia States

Wu, J., Liu, D.-Q., Li, J., Sun, J., Huang, Y., Zhang, S., Gao, S., & Mei, W. (2021) · Current Neuropharmacology · doi:10.2174/1570159x19666210225152728 · Cited by 8

Commentary on Kaushik et al.: Prostaglandin D2 is crucial for seizure suppression and postictal sleep. Novel evidence supporting a role for prostanoid receptors in seizure control

Mello, C. F., & Oliveira, M. S. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2014.05.002 · Cited by 9

Structural insights into the mechanism of activation and inhibition of the prostaglandin D2 receptor 1

Davoudinasab, B., Raskovalov, A., Lee, W., Kim, D., Kim, H., Lam, J. H., Han, G. W., Katritch, V., & Cherezov, V. (2025) · Nature Communications · doi:10.1038/s41467-025-64002-z · Cited by 8

Hematopoietic Prostaglandin D Synthase Is Increased in Mast Cells and Pericytes in Autopsy Myocardial Specimens from Patients with Duchenne Muscular Dystrophy

Hamamura, K., Yoshida, Y., Oyama, K., Li, J., Kawano, S., Inoue, K., Toyooka, K., Yamadera, M., Matsunaga, N., Matsumura, T., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031846 · Cited by 8

Sleep, Immunity, and Stress: Novel Insights From Drosophila

Williams, J. A. (2019) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-813743-7.00023-2 · Cited by 8

Lipocalin-type prostaglandin D synthase regulates light-induced phase advance of the central circadian rhythm in mice

Kawaguchi, C., Shintani, N., Hayata‐Takano, A., Hatanaka, M., Kuromi, A., Nakamura, R. M., Yamano, Y., Shintani, Y., Nagai, K., Tsuchiya, S., et al. (2020) · Communications Biology · doi:10.1038/s42003-020-01281-w · Cited by 8

Brain Prostaglandin D2 Increases Neurogenic Pressor Activity and Mean Arterial Pressure in Angiotensin II-Salt Hypertensive Rats

Asirvatham‐Jeyaraj, N., Jones, A. D., Burnett, R. J., & Fink, G. D. (2019) · Hypertension · doi:10.1161/hypertensionaha.119.13175 · Cited by 8

Global Transcriptomic Analysis of the Canine corpus luteum (CL) During the First Half of Diestrus and Changes Induced by in vivo Inhibition of Prostaglandin Synthase 2 (PTGS2/COX2)

Pereira, M. T., Graubner, F. R., Rehrauer, H., Janowski, T. E., Hoffmann, B., Boos, A., & Kowalewski, M. P. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00715 · Cited by 8

Physiologic Advantages of Peripheral Nerve Blockade Translate to Decreased Length of Stay and Improved Patient Satisfaction

Kerfeld, M. J., Hambsch, Z. J., McEntire, D., Kirkpatrick, D. R., Cai, J., Youngblood, C. F., Agrawal, D. K., & Reisbig, M. D. (2016) · Research and Practice in Anesthesiology – Open Journal · doi:10.17140/aoj-1-103 · Cited by 7

Association of Hypovitaminosis D with Sleep Parameters in Rotating Shift Worker Drivers

de Menezes-Júnior, L. A. A., Fajardo, V. C., Neto, R. M. D. N., de Freitas, S. N., de Oliveira, F. L. P., Pimenta, F. A. P., Machado-Coelho, G. L. L., & Meireles, A. L. (2023) · Sleep Science · doi:10.1055/s-0043-1767748 · Cited by 7

Effect of Yokukansan on sleep disturbance in a rat model of cerebrovascular dementia

Nagao, M., Takasaki, K., Nogami, A., Hirai, Y., Moriyama, H., Uchida, N., Kubota, K., Katsurabayashi, S., Mishima, K., Nishimura, R., et al. (2014) · Traditional & Kampo Medicine · doi:10.1002/tkm2.1008 · Cited by 7

Application of Braided Piezoelectric Poly-l-Lactic Acid Cord Sensor to Sleep Bruxism Detection System with Less Physical or Mental Stress

Tajitsu, Y., Shimda, S., Nonomura, T., Yanagimoto, H., Nakamura, S., Ueshima, R., Kawanobe, M., Nakiri, T., Takarada, J., Takeuchi, O., et al. (2023) · Micromachines · doi:10.3390/mi15010086 · Cited by 6

Neurobiology of African Trypanosomiasis

Masocha, W., Kristensson, K., & Rottenberg, M. E. (2014) · Springer eBooks · doi:10.1007/978-1-4614-8100-3_10 · Cited by 6

Substrate-induced product-release mechanism of lipocalin-type prostaglandin D synthase

Shimamoto, S., Nakagawa, Y., Hidaka, Y., Maruno, T., Kobayashi, Y., Kawahara, K., Yoshida, T., Ohkubo, T., Aritake, K., Kaushik, M. K., et al. (2021) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2021.06.092 · Cited by 6

Differences in Polysomnography Parameters of Women in the Post and Transitional Phases of Menopause

Duğral, E., & Ordu, G. (2021) · Cureus · doi:10.7759/cureus.20570 · Cited by 6

Impact of antiallergy agents on CPAP therapy and sleep quality with spring pollinosis in Japanese

Yoshikawa, A., Inoshita, A., Sata, N., Nakamura, M., Suzuki, Y., Ishimizu, E., Suda, S., Naito, R., Kasai, T., & Matsumoto, F. (2023) · Sleep And Breathing · doi:10.1007/s11325-023-02788-2 · Cited by 7

Cyclooxygenase-2 (COX-2)-dependent mechanisms mediate sleep responses to microbial and thermal stimuli

Szentirmai, É., Buckley, K., & Kapás, L. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.08.014 · Cited by 6

Neurobiological Basis of Hypersomnia

Urade, Y. (2017) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2017.03.003 · Cited by 6

Thermodynamic and NMR analyses of NADPH binding to lipocalin-type prostaglandin D synthase

Qin, S., Shimamoto, S., Maruno, T., Kobayashi, Y., Kawahara, K., Yoshida, T., & Ohkubo, T. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.10.124 · Cited by 6

Hypovitaminosis D is associated with sleep disorders in workers on alternating shifts with cardiovascular risk factorsPreprint

de Menezes-Júnior, L. A. A., Fajardo, V. C., de Freitas, S. N., Pimenta, F. A. P., de Oliveira, F. L. P., Machado-Coelho, G. L. L., Neto, R. M. D. N., & Meireles, A. L. (2021) · medRxiv · doi:10.1101/2021.05.04.21256625 · Cited by 6

Pericytes in Brain Homeostasis: Developmental Roles and Adult Functions

Drozd, U. S., Vechkapova, S. O., & Lanshakov, D. A. (2025) · Frontiers in Bioscience-Landmark · doi:10.31083/fbl42742 · Cited by 4

The vasoconstrictor activities of prostaglandin D2 via the thromboxane prostanoid receptor and E prostanoid receptor-3 outweigh its concurrent vasodepressor effect mainly through D prostanoid receptor-1 ex vivo and in vivo

Guo, T., Liu, B., Zeng, R., Lin, R., Guo, J., Yu, G., Xu, Y., Tan, X., Xie, K., & Zhou, Y. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.175963 · Cited by 5

Major depressive disorder (mdd): emerging immune targets at preclinical level

Varma, M., Kaur, A., Bhandari, R., Kumar, A., & Kuhad, A. (2023) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2023.2225216 · Cited by 6

Prostanoid receptors (version 2019.5) in the IUPHAR/BPS Guide to Pharmacology Database

BREYER, R. M., Clapp, L. H., Coleman, R. A., Giembycz, M. A., Heinemann, Á., Hills, R., Jones, R. L., Narumiya, S., Norel, X., Pettipher, R., et al. (2019) · IUPHAR/BPS Guide to Pharmacology CITE · doi:10.2218/gtopdb/f58/2019.5 · Cited by 5

Nutrition and Sleep

Partinen, M. (2017) · Springer eBooks · doi:10.1007/978-1-4939-6578-6_30 · Cited by 6

ATP-Binding Cassette Transporter C4 is a Prostaglandin D2 Exporter in HMC-1 cells

Tanaka, N. K., Kawai, J., Hirasawa, N., Mano, N., & Yamaguchi, H. (2020) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2020.102139 · Cited by 5

Molecular basis for ligand recognition and receptor activation of the prostaglandin D2 receptor DP1

Xu, J., Wu, Y., Xu, Y., Li, Y., He, X., Zhang, H., Wang, J. J., Hou, J., Li, J., Hu, W., et al. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2501902122 · Cited by 4

Adenosinergic Regulation of Sleep–Wake Behavior in the Basal Ganglia

Lazarus, M., & Urade, Y. (2015) · Current topics in neurotoxicity · doi:10.1007/978-3-319-20273-0_15 · Cited by 4

Linking Vitamin D and Sleep

Archontogeorgis, K., Nena, E., & Steiropoulos, P. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816658-1.00038-7 · Cited by 4

Fluid Analysis in CSF Rhinorrhea

Alsaleh, S. A., Muathen, S. H., & Javer, A. R. (2022) · Springer eBooks · doi:10.1007/978-3-030-94781-1_5 · Cited by 4

Impact of IL-33 on PGD2 Generation by Activated Human Cord Blood-Derived Mast Cell: Lack of Effect on Tryptase Release

Nicoletti, M., Maccauro, G., Tripodi, D., Saggini, A., Potalivo, G., Castellani, M. L., Conti, F., Rosati, M., Tomato, E., Caraffa, A., et al. (2012) · European Journal of Inflammation · doi:10.1177/1721727x1201000323 · Cited by 4

Role of Sleep in Cognition, Immunity, and Disease and Its Interaction with Exercise

Zielinski, M. R., & Gerashchenko, D. (2015) · Wiley eBooks · doi:10.1002/9781118840634.ch20 · Cited by 4

Phytotherapeutic agents for insomnia: A scoping review on the mechanistic insights and evidence from animal models

Castillo, A. L., Villaflores, O. B., Kuroki, Y., Wada, A. M., Zhu, X., Cabatit, K. A., Garcia, J. J., Martin, J., & Vasquez, R. D. (2025) · Phytomedicine Plus · doi:10.1016/j.phyplu.2025.100770 · Cited by 3

Polyunsaturated Fatty Acids in Relation to Sleep Quality and Depression in Obstructive Sleep Apnea Hypopnea Syndrome

Papandreou, C. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-410527-0.00027-2 · Cited by 3

Prostanoid receptors (version 2020.4) in the IUPHAR/BPS Guide to Pharmacology Database

BREYER, R. M., Clapp, L. H., Coleman, R. A., Giembycz, M. A., Heinemann, Á., Hills, R., Jones, R. L., Narumiya, S., Norel, X., Pettipher, R., et al. (2020) · IUPHAR/BPS Guide to Pharmacology CITE · doi:10.2218/gtopdb/f58/2020.4 · Cited by 3

Molecular species of prostaglandins involved in modulating luteinising hormone pulses of female rats under infectious stress conditions

Matsuwaki, T., Komatsuda, M., Fujisawa, A., Doke, M., Yamanouchi, K., & Nishihara, M. (2017) · Journal of Neuroendocrinology · doi:10.1111/jne.12490 · Cited by 3

Prostanoid receptors in GtoPdb v.2023.1

Clapp, L. H., Giembycz, M. A., Heinemann, Á., Jones, R. L., Narumiya, S., Norel, X., Sugimoto, Y., Woodward, D. F., & Yao, C. (2023) · IUPHAR/BPS Guide to Pharmacology CITE · doi:10.2218/gtopdb/f58/2023.1 · Cited by 3

Activation of the arachidonic acid metabolic pathway and induction of sleep disturbance by sacral osteoblastoma: A case report

Ozaki, M., Nishioka, K., Kimura, A., Kondo, T., & Nakao, N. (2017) · Molecular and Clinical Oncology · doi:10.3892/mco.2017.1313 · Cited by 3

Physiological Roles and Mechanisms of Sleep

Uchiyama, M. (2020) · Journal of Nihon University Medical Association · doi:10.4264/numa.79.6_327 · Cited by 3

The Role of Glia in Sleep-Wake Regulation and Function

Frank, M. G. (2019) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-813743-7.00013-x · Cited by 3

Neurobiology of Dream Activity and Effects of Stimulants on Dream

Murillo‐Rodríguez, E., Coronado-Álvarez, A., López-Muciño, L. A., Pastrana-Trejo, J. C., Viana-Torre, G., Barberena, J. J., Soriano-Nava, D. M., & García‐García, F. (2022) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026622666220627162032 · Cited by 4

In Memoriam: Osamu Hayaishi (1920–2015)

Narumiya, S., Shimizu, T., & Yamamoto, S. (2016) · Journal of Lipid Research · doi:10.1194/jlr.e067579 · Cited by 1

Chronic sleep deprivation induces depression- and Alzheimer’s disease-like changes in adult and ageing wild-type and Fat-1 transgenic mice

Niazi, N. U. K., Yang, Z., Zhang, Y., & Song, C. (2025) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2025.102699 · Cited by 3

FADS1 contributes to anesthesia/surgery-induced cognitive impairment by aggravating omega-6 fatty acid metabolic disruption in aged mice

Chen, Z., Wu, Q., Ma, J., Shi, Y., Zhang, Q., Wu, H., Zhang, Y., Li, Z., Ruan, X., Xiong, L., et al. (2026) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03678-y · Cited by 2

The role of prostanoids in the retina and optic nerve in health and disease

Ward, E. L., Karnam, S., Changavi, A., Kumar, M., Maurya, S., Margeta, M. A., Sivak, J. M., Gronert, K., & Flanagan, J. G. (2026) · Progress in retinal and eye research · doi:10.1016/j.preteyeres.2026.101460 · Cited by 2

Osamu Hayaishi—from the discovery of oxygenases in soil microorganisms to unraveling the enigma of sleep in mammals

Lazarus, M., Huang, Z., & Urade, Y. (2015) · Temperature · doi:10.1080/23328940.2015.1072658 · Cited by 2

Attenuation of Laser-Induced Choroidal Neovascularization by Blockade of Prostaglandin D2 Receptor 2

Soga, H., Inoue, T., Urade, Y., Ueta, T., Kawashima, H., Kaburaki, T., & Aihara, M. (2023) · Translational Vision Science & Technology · doi:10.1167/tvst.12.5.5 · Cited by 2

Metabolic signals in sleep regulation: the role of brown adipose tissue

Szentirmai, É., & Kapás, L. (2025) · Neurobiology of Sleep and Circadian Rhythms · doi:10.1016/j.nbscr.2025.100122 · Cited by 3

Astroglial regulation of sleep

Frank, M. G. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139649469.011 · Cited by 3

Prostaglandin D2 elicits the reversible neurite retraction in hypothalamic cell line

Tsuchiya, H., Hohjoh, H., Fujiwara, Y., Sugimoto, Y., & Koshimizu, T. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.01.091 · Cited by 2

Enzymatic Oxidation of Polyunsaturated Fatty Acids

MURPHY, S. A., Al‐Aasswad, N. M. I., & Nicolaou, A. (2015) · Oxidative stress and disease · doi:10.1201/b18138-5 · Cited by 2

A gain-of-function study of amelioration of pentylenetetrazole-induced seizures by endogenous prostaglandin D2

Kaushik, M. K., Aritake, K., Chérasse, Y., Sharma, R., & Urade, Y. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.09.011 · Cited by 2

NREM sleep: anatomy and physiology

Alam, M. N., Kostin, A., & Alam, A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822963-7.00227-9 · Cited by 2

The Effect of Sleep Disruption and Circadian Misalignment on the Immune System

Garbarino, S., Bragazzi, N. L., & Scoditti, E. (2023) · Progress in Sleep Research · doi:10.1007/978-981-99-0240-8_1 · Cited by 1

Enzymatic Oxidation of Polyunsaturated Fatty Acids

Nicolaou, A., Murphy, S., & Al-Aaswad, N. M. (2015) · CRC Press eBooks · doi:10.1201/b18138-8 · Cited by 1

Chronic Headaches and Sleepiness Caused by Facial Soap (Containing Hydrolyzed Wheat Proteins)-Induced Wheat Allergy

Iseki, C., Kawanami, T., Tsunoda, T., Chinuki, Y., & Kato, T. (2014) · Internal Medicine · doi:10.2169/internalmedicine.53.0744 · Cited by 1

Geneticsof sleep and circadian rhythms

Shaw, P. J., Tafti, M., & Thorpy, M. J. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139649469.006 · Cited by 1

Post-transcriptional Regulation of Prostaglandin Biosynthesis

Blanco, F. F., Legrand, N., Sobolewski, C., & Dixon, D. A. (2015) · Springer eBooks · doi:10.1007/978-3-319-25124-0_9 · Cited by 1

Glial Modulation of Sleep and Electroencephalographic Rhythms

Frank, M. G. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-384995-3.00003-4 · Cited by 1

Efecto analgésico y sobre la neuroconducta de la interacción entre tramadol y diclofenaco en dosis escalonada en ratones

Salazar‐Granara, A., Torres-Acosta, L., de la Portilla, A. S., Palacios-Ramírez, S., Vergara-Ascenzo, C. A., Angulo, C. T., & Pante-Medina, C. (2016) · ACTA MEDICA PERUANA · doi:10.35663/amp.2015.322.134 · Cited by 1

General Principle of Treatment of Sleep Dysfunction and Pharmacology of Drugs Used in Sleep Disorders

Monti, J. (2017) · Springer eBooks · doi:10.1007/978-1-4939-6578-6_55 · Cited by 1

Basic Pharmacologic Mechanisms of Sleep

Monti, J. M. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-378610-4.00118-2

Modulation of ion transport in inflammatory bowel diseases: regulatory targets

Romero‐Calvo, I. (2014) · Institutional Repository of the University of Granada (University of Granada)

RBC fatty acid profile and sleep conditions in depression patients-a post-hoc analysis

Epa, M. (2013)

Advances in dyslipidemia

Aronow, W. S. (2013) · doi:10.2217/fmeb2013.13.81

Comparison of physical activity and sleep measures based on subjective and objective measures.

Walden, A. J. (2016) · doi:10.18297/etd/2387

Introduction to the Topic

Saper, C. B. (2017) · Springer eBooks · doi:10.1007/978-1-4939-6578-6_1

Dyslipidemia: current management and the challenge of residual cardiovascular risk reduction

Rockoff, A., Kamanna, V. S., & Kashyap, M. L. (2013) · doi:10.2217/fmeb2013.13.88

Cuticle Secretion Duration in the Uterus Is One of the Major Factors Affecting Eggshell Cuticle Deposition in White Leghorn Laying HensPreprint

Chen, X., He, Z., Li, X., Song, J., Huang, M., Shi, X., Li, X., Li, J., Xu, G., Yang, N., et al. (2020) · Research Square · doi:10.21203/rs.3.rs-124583/v1

Love Without Borders: TaiwanICDF Releases Sixth Online Film, “Humanity”

國合會系統管理者 (2013)

Catalysis‐Enabled Concise and Stereoselective Total Synthesis of the Tricyclic Prostaglandin D2 Metabolite Methyl Ester

Sims, H. S., Horn, P. D. A., Isshiki, R., Lim, M., Xu, Y., Grubbs, R. H., & Dai, M. (2021) · Angewandte Chemie · doi:10.1002/ange.202115633

Sleep homeostasis

Kostin, A., Alam, A., McGinty, D., & Alam, M. N. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822963-7.00243-7

Medications that disrupt sleep

Nishimon, S., & Nishino, S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822963-7.00235-8

Basic pharmacologic mechanisms of sleep

Monti, J. M., & Torterolo, P. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822963-7.00010-4

Circuits and Neurotransmitter Systems Controlling Sleep and Wake

Arrigoni, E., & Fuller, P. M. (2025) · doi:10.1093/med/9780197756782.003.0006

Activation of transposable elements is linked to a region- and cell type–specific interferon response in Parkinson’s disease

Garza, R., Adami, A., Thiruvalluvan, A., Wijesinghe, S. S., Curle, A. J., Tam, O. H., Forcier, T., Lagka, D. A., Kazakou, N.-L., Atacho, D. A. M., et al. (2026) · Science Advances · doi:10.1126/sciadv.aed2952 · Cited by 3

Neurosciences II

Miller, C. O. G. (2025) · Springer eBooks · doi:10.1007/978-3-032-13315-1_5

Exploitation d'une biobanque de patients atteints de Trypanosomose Humaine Africaine à Trypanosoma brucei gambiense : recherche et validation de biomarqueurs

Bonnet, J. (2017) · theses.fr (ABES) · doi:10.70675/3064bc89zacb1z4dfez8fe7z289a7fc067d5

Cell neogenesis in the postnatal hypothalamus as a new mechanism of control of the reproductive function

Pellegrino, G. (2017) · theses.fr (ABES) · doi:10.70675/49c584f3z87f6z4320z924bz64015ded1e39

Recherche de nouvelles molécules trypanocides

Boudot, C. (2019) · doi:10.70675/ef061f97z6f1fz42f7z8f9fzdfcdafb6cc08

Microglial dynamics in physiological conditions : a vigilance state and neuronal activity-driven mechanism

Hristovska, I. (2019) · theses.fr (ABES) · doi:10.70675/af1c5105z3e0dz43ffzb906z1553e7a23a6e

Gliogenèse hypothalamique et contrôle de la fonction de reproduction

Martin, M. J. (2021) · theses.fr (ABES) · doi:10.70675/0650653dz87dez4961z9536z23565f173f47

From sleep homeostasis to cellular constraints in neurons

Shi, S. (2026) · Neuroscience Research · doi:10.1016/j.neures.2026.105065

Clinical Study on Combining Traditional Chinese Medicine With Acupuncture for Treating Insomnia Accompanied by Anxiety

Mao, X.-W., & Bai, P. (2026) · Brain and Behavior · doi:10.1002/brb3.71431

From plate to pillow: the role of food-derived bioactive compounds in sleep modulation and the potential of glia–neuron crosstalk

Li, Z., Guo, Y., Ma, D., Cheng, Y., Rahman, E., Wang, Z., Chen, Q., MaoMao, Z., Chen, J., Liu, G., et al. (2026) · Food & Function · doi:10.1039/d6fo02383e

BindingDB Entry 50002853: Characterization of crystal water molecules in a high-affinity inhibitor and hematopoietic prostaglandin D synthase complex by interaction energy studies.

BindingDB (2020) · UC San Diego · doi:10.7270/q2vh5rjq

Crucial role of prostaglandin D 2 and adenosine in sleep regulation: experimental evidence from pharmacological approaches to gene-knockout mice

Urade, Y., & Hayaishi, O. (2010) · Future Neurology · doi:10.2217/fnl.10.18 · Cited by 17

Prostaglandin D2 and adenosine as endogenous somnogens

Urade, Y. (2011) · Sleep and Biological Rhythms · doi:10.1111/j.1479-8425.2010.00470.x · Cited by 7

Prostaglandins and adenosine in the regulation of sleep and wakefulness

Huang, Z., Urade, Y., & Hayaishi, O. (2006) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2006.09.004 · Cited by 227

＜Special Seminar＞Molecular mechanism of sleep-wake regulation

Urade, Y. (2010) · Institutional Repositories DataBase (IRDB)

Prostaglandin D2 and sleep regulation

Urade, Y., & Hayaishi, O. (1999) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s0005-2760(98)00163-5 · Cited by 159