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Cited by 447

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Direct Conversion of Fibroblasts into Stably Expandable Neural Stem Cells

Thier, Marc, Wörsdörfer, Philipp, Lakes, Yenal B., Gorris, Raphaela, Herms, Stefan, Opitz, Thoralf, Seiferling, Dominic, Quandel, Tamara, Hoffmann, Per, Nöthen, Markus M., Brüstle, Oliver, Edenhofer, Frank·2012·Cell Stem Cell
DOI 10.1016/j.stem.2012.03.003
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Crossref · 10.1016/j.stem.2012.03.003

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5 of 5 references verified0 citation errors · 0 not checkable

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  • Partial reprogramming in vitro by transient expression of OSKM can induce a dedifferentiated progenitor-like state.

    “partial reprogramming in vitro by transient expression of OSKM can induce a dedifferentiated progenitor-like state”

    From In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming. (2016) · cites this paper as Thier et al., 2012

    The Results describe converting fibroblasts into neural stem cells through curtailed reprogramming, supporting the progenitor-like outcome. But the Results and Discussion specify a temporary pulse of Oct4 while Sox2, Klf4, and c-Myc were initially expressed constitutively; the paper does not describe transient expression of all four OSKM factors. (LLM, conf=0.88)

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Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 23

  1. Bosnali, 2008, Generation of transducible versions of transcription factors Oct4 and Sox2, Biol. Chem., 389, 851, 10.1515/BC.2008.106 · DOI
  2. Brambrink, 2008, Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells, Cell Stem Cell, 2, 151, 10.1016/j.stem.2008.01.004 · DOI
  3. Caiazzo, 2011, Direct generation of functional dopaminergic neurons from mouse and human fibroblasts, Nature, 476, 224, 10.1038/nature10284 · DOI
  4. Conti, 2005, Niche-independent symmetrical self-renewal of a mammalian tissue stem cell, PLoS Biol., 3, e283, 10.1371/journal.pbio.0030283 · DOI
  5. Efe, 2011, Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy, Nat. Cell Biol., 13, 215, 10.1038/ncb2164 · DOI
  6. Glaser, 2007, Tripotential differentiation of adherently expandable neural stem (NS) cells, PLoS ONE, 2, e298, 10.1371/journal.pone.0000298 · DOI
  7. Graf, 2009, Forcing cells to change lineages, Nature, 462, 587, 10.1038/nature08533 · DOI · Paper page
  8. Ieda, 2010, Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors, Cell, 142, 375, 10.1016/j.cell.2010.07.002 · DOI · Paper page
  9. Kim, 2011, Direct reprogramming of mouse fibroblasts to neural progenitors, Proc. Natl. Acad. Sci. USA, 108, 7838, 10.1073/pnas.1103113108 · DOI
  10. Lujan, 2012, Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells, Proc. Natl. Acad. Sci. USA, 109, 2527, 10.1073/pnas.1121003109 · DOI
  11. Pang, 2010, Induction of human neuronal cells by defined transcription factors, Nature, 476, 220, 10.1038/nature10202 · DOI
  12. Pfisterer, 2011, Direct conversion of human fibroblasts to dopaminergic neurons, Proc. Natl. Acad. Sci. USA, 108, 10343, 10.1073/pnas.1105135108 · DOI
  13. Pollard, 2006, Adherent neural stem (NS) cells from fetal and adult forebrain, Cereb. Cortex, 16, i112, 10.1093/cercor/bhj167 · DOI
  14. Sheng, 2011, Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors, Cell Res., 22, 208, 10.1038/cr.2011.175 · DOI
  15. Soldner, 2009, Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors, Cell, 136, 964, 10.1016/j.cell.2009.02.013 · DOI
  16. Szabo, 2010, Direct conversion of human fibroblasts to multilineage blood progenitors, Nature, 468, 521, 10.1038/nature09591 · DOI
  17. Thier, 2010, Exploring refined conditions for reprogramming cells by recombinant Oct4 protein, Int. J. Dev. Biol., 54, 1713, 10.1387/ijdb.103193mt · DOI
  18. Tropepe, 2001, Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism, Neuron, 30, 65, 10.1016/S0896-6273(01)00263-X · DOI
  19. Uchida, 2000, Direct isolation of human central nervous system stem cells, Proc. Natl. Acad. Sci. USA, 97, 14720, 10.1073/pnas.97.26.14720 · DOI
  20. Yamanaka, 2010, Nuclear reprogramming to a pluripotent state by three approaches, Nature, 465, 704, 10.1038/nature09229 · DOI
  21. Yoo, 2011, MicroRNA-mediated conversion of human fibroblasts to neurons, Nature, 476, 228, 10.1038/nature10323 · DOI · Paper page
  22. Zhou, 2008, Extreme makeover: converting one cell into another, Cell Stem Cell, 3, 382, 10.1016/j.stem.2008.09.015 · DOI
  23. Zhou, 2009, Generation of induced pluripotent stem cells using recombinant proteins, Cell Stem Cell, 4, 381, 10.1016/j.stem.2009.04.005 · DOI · Paper page

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Metadata

Authors
Thier, M., Wörsdörfer, P., Lakes, Y. B., Gorris, R., Herms, S., Opitz, T., Seiferling, D., Quandel, T., Hoffmann, P., Nöthen, M. M., Brüstle, O., & Edenhofer, F.
Venue
Cell Stem Cell
Publisher
Elsevier BV
Published
2012-04
Volume
10
Issue
4
Pages
473-479
ISSN
1934-5909
DOI
10.1016/j.stem.2012.03.003
Cited by
447
References
5
Language
en
Licence
Funders
  • Bundesministerium für Bildung und Forschung (01GN1009B)
  • Merck KGaA
  • European Commission
  • Deutsche Forschungsgemeinschaft (ED79/1-2)

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