The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal
Open accessAbstract
Small, rapidly dividing pluripotent stem cells (PSCs) have unique energetic and biosynthetic demands compared with typically larger, quiescent differentiated cells. Shifts between glycolysis and oxidative phosphorylation with PSC differentiation or reprogramming to pluripotency are accompanied by changes in cell cycle, biomass, metabolite levels, and redox state. PSC and cancer cell metabolism are overtly similar, with metabolite levels influencing epigenetic/genetic programs. Here, we discuss the emerging roles for metabolism in PSC self-renewal, differentiation, and reprogramming.
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Cites
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Self-citationATP-citrate lyase links cellular metabolism to histone acetylation
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Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis
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Cited by
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
Stincone, A., Prigione, A., Cramer, T., Wamelink, M. M. C., Campbell, K., Cheung, E., Olin‐Sandoval, V., Grüning, N., Krüger, A., Tauqeer Alam, M., et al. (2015) · Biological Reviews · doi:10.1111/brv.12140 · Cited by 1,576
Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
Carey, B. W., Finley, L. W. S., Cross, J. R., Allis, C. D., & Thompson, C. B. (2015) · Nature · doi:10.1038/nature13981 · Cited by 1,007
Stem cells and the impact of ROS signaling
Bigarella, C. L., Liang, R., & Ghaffari, S. (2014) · Development · doi:10.1242/dev.107086 · Cited by 632
Elucidating cancer metabolic plasticity by coupling gene regulation with metabolic pathways
Jia, D., Lu, M., Jung, K. H., Park, J. H., Yu, L., Onuchic, J. N., Kaipparettu, B. A., & Levine, H. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1816391116 · Cited by 336
Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing
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Metadata
- Authors
- Zhang, J., Nuebel, E., Daley, G. Q., Koehler, C. M., & Teitell, M. A.
- Venue
- Cell Stem Cell
- Publisher
- Elsevier BV
- Published
- 2012-11
- Volume
- 11
- Issue
- 5
- Pages
- 589-595
- ISSN
- 1875-9777 (ISSN-L)
- 1934-5909
- OpenAlex
- W2111993114
- Cited by
- 471
- References
- 12
- FWCI
- 10.69
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Zhang, J., Nuebel, E., Daley, G. Q., Koehler, C. M., & Teitell, M. A. (2012). Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal. Cell Stem Cell. https://doi.org/10.1016/j.stem.2012.10.005
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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