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Deciphering the roadmap of in vivo reprogramming toward pluripotency
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Single-cell transcriptomic monitoring of reprogramming in the pancreas identified intermediate reprogramming states.
“the authors, in a related study, monitored the roadmap of reprogramming in the pancreas and identified intermediate reprogramming states by using a single-cell transcriptomic”
From Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming (2023) · cites this paper as [107]
OSKM overexpression has drastically different effects on different cell types within the same organ.
“This study also highlights how OSKM overexpression has drastically different effects on different cell types within the same organ.”
From Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming (2023) · cites this paper as [107]
The different effects of OSKM overexpression on cell types within the same organ are probably due to different plasticity or susceptibility of the cell types to reprogramming.
“This is probably due to the different plasticity or susceptibility of the different cell types to reprogramming”
From Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming (2023) · cites this paper as [107]
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Senescence impairs successful reprogramming to pluripotent stem cells
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Cited by
Sorted by citations
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming
Cipriano, A., Moqri, M., Maybury-Lewis, S. Y., Rogers-Hammond, R., de Jong, T. A., Parker, A., Rasouli, S., Schöler, H. R., Sinclair, D. A., & Sebastiano, V. (2023) · Nature Aging · doi:10.1038/s43587-023-00539-2 · Cited by 66
Vitamin B12 is a limiting factor for induced cellular plasticity and tissue repair
Kovatcheva, M., Melendez, E., Chondronasiou, D., Pietrocola, F., Bernad, R., Caballe, A., Junza, A., Capellades, J., Holguín-Horcajo, A., Prats, N., et al. (2023) · Nature Metabolism · doi:10.1038/s42255-023-00916-6 · Cited by 58
Self-citationCellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective
Huyghe, A., Trajkova, A., & Lavial, F. (2024) · Trends in Cell Biology · doi:10.1016/j.tcb.2023.07.013 · Cited by 56
Metadata
- Authors
- Chondronasiou, D., Martínez de Villarreal, J., Melendez, E., Lynch, C. J., Pozo, N. D., Kovatcheva, M., Aguilera, M., Prats, N., Real, F. X., & Serrano, M.
- Venue
- Stem Cell Reports
- Publisher
- Elsevier BV
- Published
- 2022-11
- Volume
- 17
- Issue
- 11
- Pages
- 2501-2517
- ISSN
- 2213-6711
- PMC
- PMC9669407
- Cited by
- 34
- References
- 16
- Language
- en
- Licence
- Funders
- Ministerio de Economía y Competitividad
- European Commission
- European Research Council (2017 SGR 282, ERC-2014-AdG/669622)
- Fundación Científica Asociación Española Contra el Cáncer
- Ministerio de Ciencia e Innovación
- European Regional Development Fund (RTI2018-101071-B-I00, SAF2015-70553-R, SAF2017-82613-R)
- Milky Way Research Foundation
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