AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs

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Items 401–500 of 860

1. Molecular mechanisms of appetite and obesity: a role for brain AMPK
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2. Integration of proteomics and metabolomics reveals promotion of proliferation by exposure of bisphenol S in human breast epithelial MCF-10A cells
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3. Increased mTOR and suppressed autophagic flux in the heart of a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease
   Daniel J. Atwood, Deepak Pokhrel, Carolyn Nicole Brown, Sara J. Holditch, Dheevena M Bachu, Andrew M. Thorburn, Katharina Hopp, Charles L. Edelstein · 2020 · Cellular Signalling
4. AMPK-deficiency forces metformin-challenged cancer cells to switch from carbohydrate metabolism to ketogenesis to support energy metabolism
   Flávio Romero Palma, Bianca Altrão Ratti, Verônica Paviani, Diego Rodrigues Coelho, Rodrigo Bernardi Miguel, Jeanne M. Danes, Sofia V. Zaichik, Andre Luelsdorf de Abreu, Sueli de Oliveira Silva, Yiliang Chen et al. · 2021 · Oncogene
5. Hypoxic and Thermal Stress: Many Ways Leading to the NOS/NO System in the Fish Heart
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6. Berberine Influences the Survival of Fat Grafting by Inhibiting Autophagy and Apoptosis of Human Adipose Derived Mesenchymal Stem Cells
   Hao Pang, Yongting Zhou, Jie Wang, Hao Wu, Xueyi Liu, Feng Gao, Zhibo Xiao · 2021 · Drug Design Development and Therapy
7. Lactobacillus delbrueckii might lower serum triglyceride levels via colonic microbiota modulation and SCFA-mediated fat metabolism in parenteral tissues of growing-finishing pigs
   Gaifeng Hou, Jie Lin Yin, Wei LiangKai, Rui Li, Wei Peng, Yong Yuan, Xingguo Huang, Yulong Yin · 2022 · Frontiers in Veterinary Science
8. Discovery of new substrates of the elongation factor-2 kinase suggests a broader role in the cellular nutrient response
   Michael B. Lazarus, Rebecca S. Levin, Kevan M. Shokat · 2016 · Cellular Signalling
9. Glucose-dependent regulation of pregnane X receptor is modulated by AMP-activated protein kinase
   Peter O. Oladimeji, Wenwei Lin, Christopher Brewer, Taosheng Chen · 2017 · Scientific Reports
10. AMPK and the Need to Breathe and Feed: What’s the Matter with Oxygen?
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11. The Protective Role of Decorin in Hepatic Metastasis of Colorectal Carcinoma
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12. Effect of pre-slaughter shackling and wing flapping on plasma parameters, postmortem metabolism, AMPK, and meat quality of broilers
    Jichao Huang, J. Yang, M Huang, Zongshuai Zhu, X.B. Sun, B.H. Zhang, Xu Xinglian, W.G. Meng, K.J. Chen, Baocai Xu · 2018 · Poultry Science
13. A CRISPR knockout negative screen reveals synergy between CDKs inhibitor and metformin in the treatment of human cancer in vitro and in vivo
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14. Human Cytomegalovirus Strategies to Maintain and Promote mRNA Translation
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15. Activation and inhibition of Snf1 kinase activity by phosphorylation within the activation loop
    Rhonda R. McCartney, Leopold Garnar-Wortzel, Dakshayini G. Chandrashekarappa, Martin C. Schmidt · 2016 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
16. Metformin Potentiates the Benefits of Dietary Restraint: A Metabolomic Study
    Marta Riera-Borrull, Anabel García‐Heredia, Salvador Fernández‐Arroyo, Anna Hernández‐Aguilera, Noemí Cabré, Elisabet Cuyàs, Fedra Luciano‐Mateo, Jordi Camps, Javier Abel Menéndez, Jorge Joven · 2017 · International Journal of Molecular Sciences
17. Empagliflozin therapy and insulin resistance-associated disorders: effects and promises beyond a diabetic state
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18. The red pepper’s spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKKβ
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19. Systemic Candida albicans Infection in Mice Causes Endogenous Endophthalmitis via Breaching the Outer Blood-Retinal Barrier
    Sneha Singh, Sukhvinder Singh, Ashok Kumar · 2022 · Microbiology Spectrum
20. Acetylsalicylic-acid (ASA) regulation of osteo/odontogenic differentiation and proliferation of human dental pulp stem cells (DPSCs) in vitro
    Mladen Vukovic, Miloš M. Lazarević, Dijana Mitić, Milica Jakšić Karišik, Branislav Ilić, Miroslav Andrić, Bojan Jevtić, Jelena Roganović, Jelena Milašin · 2022 · Archives of Oral Biology
21. How will warming affect the growth and body size of the largest extant amphibian? More than the temperature–size rule
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22. Hypoxic State of Cells and Immunosenescence: A Focus on the Role of the HIF Signaling Pathway
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23. Early Treatment With Metformin in a Mice Model of Complex Regional Pain Syndrome Reduces Pain and Edema
    Vaskar Das, Jeffrey S. Kroin, Mario M. Moric, Robert J. McCarthy, Asokumar Buvanendran · 2019 · Anesthesia & Analgesia
24. Mitochondrial dysfunction, AMPK activation and peroxisomal metabolism: A coherent scenario for non-canonical 3-methylglutaconic acidurias
    Jòseph Vamecq, Bérengère Papegay, Vincent Nuyens, Jean G. Boogaerts, Oberdan Léo, Véronique Kruys · 2019 · Biochimie
25. An acylhydroquinone derivative produces OXPHOS uncoupling and sensitization to BH3 mimetic ABT-199 (Venetoclax) in human promyelocytic leukemia cells
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26. Metformin attenuates trauma‐induced heterotopic ossification via inhibition of Bone Morphogenetic Protein signalling
    Hui Lin, Fuli Shi, Shanshan Jiang, Yuanyuan Wang, Junrong Zou, Ying Ying, Deqiang Huang, Lingyu Luo, Xiaohua Yan, Zhijun Luo · 2020 · Journal of Cellular and Molecular Medicine
27. Chronic Ouabain Prevents Na,K-ATPase Dysfunction and Targets AMPK and IL-6 in Disused Rat Soleus Muscle
    Кравцова Виолетта Васильевна, Inna I. Paramonova, Natalia A. Vilchinskaya, Maria V. Tishkova, Vladimir V. Matchkov, Boris S. Shenkman, Igor I. Krivoi · 2021 · International Journal of Molecular Sciences
28. Thyroid hormone receptor phosphorylation regulates acute fasting-induced suppression of the hypothalamic–pituitary–thyroid axis
    Svetlana Minakhina, Vanessa De Oliveira, Sun Young Kim, Haiyan Zheng, Fredric Edward Wondisford · 2021 · Proceedings of the National Academy of Sciences
29. Human sperm motility is downregulated by the AMPK activator A769662
    Violeta Calle-Guisado, Ana Hurtado de Llera, Lauro González‐Fernández, Maria Julia Bragado, L. J. Garcia‐Marin · 2017 · Andrology
30. Metabolic ripple effects – deciphering how lipid metabolism in cancer interfaces with the tumor microenvironment
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31. GAS6/Axl is associated with AMPK activation and attenuates H2O2-induced oxidative stress
    Zhenxing Liang, Yang Yang, Xue Wu, Chenxi Lu, Huadong Zhao, Kehan Chen, Aizhen Zhao, Xiyang Li, Jing Xu · 2022 · APOPTOSIS
32. Modulatory effect of MG-132 proteasomal inhibition on boar sperm motility during in vitro capacitation
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33. Inhibition of NF-κB Signaling-Mediated Crosstalk Between Macrophages and Preosteoblasts by Metformin Alleviates Trauma-Induced Heterotopic Ossification
    Jia Hou, Jie Chen, Jingjing Fan, Zhimin Tang, Wenwen Zhou, Hui Lin · 2023 · Inflammation
34. Host cell sensing and restoration of mitochondrial function and metabolism within Helicobacter pylori VacA intoxicated cells
    Ami Y. Seeger, Faisal Zaidi, Sammy Alhayek, Rachel Jones, Huzaifa Zohair, Robin L. Holland, Ik-Jung Kim, Steven R. Blanke · 2023 · mBio
35. Genome-wide transcriptional profiling and physiological investigation elucidating the molecular mechanism of multiple abiotic stress response in Stevia rebaudiana Bertoni
    Poonam Pal, Mamta Masand, Shikha Sharma, Romit Seth, Gopal Singh, Sanatsujat Singh, Ashok Kumar, Ram Kumar Sharma · 2023 · Scientific Reports
36. A review of structural modification and biological activities of oleanolic acid
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37. A novel PRKAG2 mutation in a Chinese family with cardiac hypertrophy and ventricular pre-excitation
    Kun‐Qi Yang, Chaoxia Lu, Ying Zhang, Yan-Kun Yang, Jia-Cheng Li, Tian Lan, Meng Xu, Peng Thim Fan, Tao Tian, Linping Wang et al. · 2017 · Scientific Reports
38. Activation of AMP-activated protein kinase (AMPK) aggravated postoperative cognitive dysfunction and pathogenesis in aged rats
    Mengya Cao, Jiakai Fang, Xueqin Wang, Yi Wang, Kaiming Duan, Feng Ye, Wen Ouyang, Jianbin Tong · 2018 · Brain Research
39. AMPK Subunits Harbor Largely Nonoverlapping Genetic Determinants for Body Fat Mass, Glucose Metabolism, and Cholesterol Metabolism
    Elko Randrianarisoa, Angela Lehn‐Stefan, Johannes Krier, Anja Böhm, Martin Heni, Martin Hrabě de Angelis, Andreas Fritsche, Hans‐Ulrich Häring, Norbert Stefan, Harald Staiger · 2019 · The Journal of Clinical Endocrinology & Metabolism
40. AMP-Activated Protein Kinase
    David Grahame Hardie · 2010 · Elsevier eBooks
41. Activated AMPK promoted the decrease of lactate production in rat Sertoli cells exposed to Zearalenone
    Peirong Cai, Zhiheng Feng, Nannan Feng, Hui Zou, Jianhong Gu, Xuezhong Liu, Zongping Liu, Yan Yuan, Jianchun Bian · 2021 · Ecotoxicology and Environmental Safety
42. Loss of hepatic Flcn protects against fibrosis and inflammation by activating autophagy pathways
    Mathieu Paquette, Ming Yan, Josué M. J. Ramírez-Reyes, Leeanna El–Houjeiri, Marco Biondini, Catherine R. Dufour, Hyeonju Jeong, Alain Pacis, Vincent Giguère, Jennifer L. Estall et al. · 2021 · Scientific Reports
43. Stachydrine alleviates lipid-induced skeletal muscle insulin resistance via AMPK/HO-1-mediated suppression of inflammation and endoplasmic reticulum stress
    Tae Woo Jung, H. Kim, S. Y. Park, W. Cho, Heeseung Oh, H. J. Lee, A.M. Abd El‐Aty, Ahmet Hacımüftüoğlu, Ji Hoon Jeong · 2022 · Journal of Endocrinological Investigation
44. Inhibition of Hepatic AMPK Pathway Contributes to Free Fatty Acids-Induced Fatty Liver Disease in Laying Hen
    Cheng Huang, Xiaona Gao, Yan Shi, Lianying Guo, Changming Zhou, Ning Li, Wei Chen, Fan Yang, Guyue Li, Zhuang Yu et al. · 2022 · Metabolites
45. Deficiency of miRNA-149-3p shaped gut microbiota and enhanced dextran sulfate sodium-induced colitis
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46. Nuciferine Ameliorates Nonesterified Fatty Acid-Induced Bovine Mammary Epithelial Cell Lipid Accumulation, Apoptosis, and Impaired Migration via Activating LKB1/AMPK Signaling Pathway
    Jinxia Li, Chenchen Zhao, Menglin Liu, Linfang Chen, Yiwei Zhu, Wenwen Gao, Xiliang Du, Yuxiang Song, Xinwei Li, Guowen Liu et al. · 2022 · Journal of Agricultural and Food Chemistry
47. Transient inhibition of mitochondrial function by chrysin and apigenin prolong longevity via mitohormesis in C. elegans
    Yu Cheng, Bing-Hao Hou, Guilin Xie, Ya-Ting Shao, Jie Yang, Chen Xu · 2023 · Free Radical Biology and Medicine
48. A Soybean Sucrose Non-Fermenting Protein Kinase 1 Gene, GmSNF1, Positively Regulates Plant Response to Salt and Salt–Alkali Stress in Transgenic Plants
    Ping Lu, Si-Yu Dai, Ling-Tao Yong, Bai-Hui Zhou, Nan Wang, Yuanyuan Dong, Weican Liu, Fawei Wang, Haoyu Yang, Xiaowei Li · 2023 · International Journal of Molecular Sciences
49. Shear Stress-Induced AMP-Activated Protein Kinase Modulation in Endothelial Cells: Its Role in Metabolic Adaptions and Cardiovascular Disease
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50. Subversion of Host Responses to Energy Insufficiency by Us3 Supports Herpes Simplex Virus 1 Replication during Stress
    Elizabeth I. Vink, James R. Smiley, Ian Mohr · 2017 · Journal of Virology
51. Undo the brake of tumour immune tolerance with antibodies, peptide mimetics and small molecule compounds targeting PD‐1/PD‐L1 checkpoint at different locations for acceleration of cytotoxic immunity to cancer cells
    Wenyi Gu, Lihui Wang, Yanheng Wu, Junping Liu · 2018 · Clinical and Experimental Pharmacology and Physiology
52. Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure
    Bin Xu, Limin Lang, Shize Li, Jianbin Yuan, Jianfa Wang, Huanmin Yang, Shuai Lian · 2019 · Animals
53. Phosphoproteomics Reveals the AMPK Substrate Network in Response to DNA Damage and Histone Acetylation
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54. Remodeling mTORC1 Responsiveness to Amino Acids by the Herpes Simplex Virus UL46 and Us3 Gene Products Supports Replication during Nutrient Insufficiency
    Elizabeth I. Vink, Sora Lee, James R. Smiley, Ian Mohr · 2018 · Journal of Virology
55. Targeting and reprogramming microglial phagocytosis of neutrophils by ginsenoside Rg1 nanovesicles promotes stroke recovery
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56. AntagomiR-451 inhibits oxygen glucose deprivation (OGD)-induced HUVEC necrosis via activating AMPK signaling
    Xi Yang, Xiaoqing He, Guodong Li, Yongqing Xu · 2017 · PLoS ONE
57. Integrated analysis of Solute carrier family-2 members reveals SLC2A4 as an independent favorable prognostic biomarker for breast cancer
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58. Novel indolic AMPK modulators induce vasodilatation through activation of the AMPK–eNOS–NO pathway
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59. Low rumen degradable starch promotes the growth performance of goats by increasing protein synthesis in skeletal muscle via the AMPK-mTOR pathway
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60. Dietary Supplementation with Lauric Acid Improves Aerobic Endurance in Sedentary Mice via Enhancing Fat Mobilization and Glyconeogenesis
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61. Controlling Pericellular Oxygen Tension in Cell Culture Reveals Distinct Breast Cancer Responses to Low Oxygen Tensions
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62. Metformin prevented high glucose-induced endothelial reactive oxygen species via OGG1 in an AMPKα-Lin-28 dependent pathway
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63. miRNAs and High-Density Lipoprotein metabolism
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64. Plasticity of Performance Curves Can Buffer Reaction Rates from Body Temperature Variation in Active Endotherms
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65. Disorders of the Musculoskeletal System
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66. Impact of silencing hepatic SREBP-1 on insulin signaling
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67. The significance of caloric restriction mimetics as anti-aging drugs
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68. The S n RK 1‐ JMJ 15‐ CRF 6 module integrates energy and mitochondrial signaling to balance growth and the oxidative stress response in Arabidopsis
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69. High-energy guanine nucleotides as a signal capable of linking growth to cellular energy status via the control of gene transcription
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70. Bioactive compounds from Artemisia dracunculus L. activate AMPK signaling in skeletal muscle
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71. Lipid Droplets and Metabolic Pathways Regulate Steroidogenesis in the Corpus Luteum
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72. AMPK is required for exercise to enhance insulin sensitivity in skeletal muscles
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73. Bidirectional regulation of adenosine 5′‐monophosphate–activated protein kinase activity by berberine and metformin in response to changes in ambient glucose concentration
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74. Molecular characteristics of AMPK and its role in regulating the phagocytosis of oyster hemocytes
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75. MiR‐8‐3p regulates hyperthermia‐induced lactate secretion by targeting PPP2R5B in boar Sertoli cells
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76. Design, synthesis, and biological evaluation of aryl piperazines with potential as antidiabetic agents via the stimulation of glucose uptake and inhibition of NADH:ubiquinone oxidoreductase
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78. The Alzheimer’s disease drug candidate J147 decreases blood plasma fatty acid levels via modulation of AMPK/ACC1 signaling in the liver
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79. Role of autophagy and its molecular mechanisms in mice intestinal tract after severe burn
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80. AMPK as a direct sensor of long-chain fatty acyl–CoA esters
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81. Hindbrain lactate regulation of hypoglycemia-associated patterns of catecholamine and metabolic-sensory biomarker gene expression in A2 noradrenergic neurons innervating the male versus female ventromedial hypothalamic nucleus
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83. Circadian Clock's Cancer Connections
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84. Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495
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88. AMP-activated protein kinase regulates the expression of human telomerase reverse transcriptase
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89. The Fast Lane of Hypoxic Adaptation: Glucose Transport Is Modulated via A HIF-Hydroxylase-AMPK-Axis in Jejunum Epithelium
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90. Defects in CISD-1, a mitochondrial iron-sulfur protein, lower glucose level and ATP production in Caenorhabditis elegans
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91. Unexpected beta-amyloid production by middle doses of resveratrol through stabilization of APP protein and AMPK-mediated inhibition of trypsin-like proteasome activity in a cell model of Alzheimer's disease
    Bong-Geum Jang, Jisun Lee, Boyoung Choi, Young Ho Koh, Min-Ju Kim · 2021 · Food and Chemical Toxicology
92. PF-06409577 Activates AMPK Signaling and Inhibits Osteosarcoma Cell Growth
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93. Do polymorphisms in protein kinase catalytic subunit alpha-1 gene associated with cancer susceptibility? a meta-analysis and systematic review
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94. Syndecan-3 Coregulates Milk Fat Metabolism and Inflammatory Reactions in Bovine Mammary Epithelial Cells through AMPK/SIRT1 Signaling Pathway
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95. The involvement of AMP-activated protein kinase α in regulating glycolysis in Yesso scallop Patinopecten yessoensis under high temperature stress
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96. Research progress of AMP-activated protein kinase and cardiac aging
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97. Diazepam Binding Inhibitor Control of Eu- and Hypoglycemic Patterns of Ventromedial Hypothalamic Nucleus Glucose-Regulatory Signaling
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98. From fasting to fat reshaping: exploring the molecular pathways of intermittent fasting-induced adipose tissue remodeling
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99. Nuclear PD-L1 compartmentalization suppresses tumorigenesis and overcomes immunocheckpoint therapy resistance in mice via histone macroH2A1
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100. Genetically Encoded Fluorescent Biosensors to Explore AMPK Signaling and Energy Metabolism
     Martin Pelosse, Cécile Cottet‐Rousselle, Alexeï Grichine, Imre Berger, Uwe Schlattner · 2016 · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions