Site-directed nucleases: a paradigm shift in predictable, knowledge-based plant breeding

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A., & Charpentier, E. (2012) · Science · doi:10.1126/science.1225829 · Cited by 17,116 · see citing works

Multiplex Genome Engineering Using CRISPR/Cas Systems

Cong, L., Ran, F. A., Cox, D., Lin, S., Barretto, R., Habib, N., Hsu, P. D., Wu, X., Jiang, W., Marraffini, L. A., et al. (2013) · Science · doi:10.1126/science.1231143 · Cited by 15,339 · see citing works

RNA-Guided Human Genome Engineering via Cas9

Mali, P., Yang, L., Esvelt, K. M., Aach, J., Guell, M., DiCarlo, J. E., Norville, J. E., & Church, G. M. (2013) · Science · doi:10.1126/science.1232033 · Cited by 9,210 · see citing works

The DNA Damage Response: Making It Safe to Play with Knives

Ciccia, A., & Elledge, S. J. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.09.019 · Cited by 4,368 · see citing works

Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors

Boch, J., Scholze, H., Schornack, S., Landgraf, A., Hahn, S., Kay, S., Lahaye, T., Nickstadt, A., & Bonas, U. (2009) · Science · doi:10.1126/science.1178811 · Cited by 2,707 · see citing works

RNA-programmed genome editing in human cells

Jinek, M., East, A., Cheng, A., Lin, S., Ma, E., & Doudna, J. (2013) · eLife · doi:10.7554/elife.00471 · Cited by 2,098 · see citing works

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

Čermák, T., Doyle, E., Christian, M. L., Wang, L., Zhang, Y., Schmidt, C. L., Baller, J. A., Somia, N. V., Bogdanove, A. J., & Voytas, D. F. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr218 · Cited by 2,034 · see citing works

A Simple Cipher Governs DNA Recognition by TAL Effectors

Moscou, M., & Bogdanove, A. J. (2009) · Science · doi:10.1126/science.1178817 · Cited by 1,992 · see citing works

Double-Strand Break End Resection and Repair Pathway Choice

Symington, L. S., & Gautier, J. (2011) · Annual Review of Genetics · doi:10.1146/annurev-genet-110410-132435 · Cited by 1,481 · see citing works

High-efficiency TALEN-based gene editing produces disease-resistant rice

Li, T., Liu, B., Spalding, M. H., Weeks, D. P., & Yang, B. (2012) · Nature Biotechnology · doi:10.1038/nbt.2199 · Cited by 1,149 · see citing works

Genome Engineering With Zinc-Finger Nucleases

Carroll, D. (2011) · Genetics · doi:10.1534/genetics.111.131433 · Cited by 1,076 · see citing works

An improved zinc-finger nuclease architecture for highly specific genome editing

Miller, J. C., Holmes, M. C., Wang, J., Guschin, D. Y., Lee, Y.-L., Rupniewski, I., Beausejour, C. M., Waite, A. J., Wang, N. S., Kim, K. A., et al. (2007) · Nature Biotechnology · doi:10.1038/nbt1319 · Cited by 1,051 · see citing works

<i>Xanthomonas</i> AvrBs3 Family-Type III Effectors: Discovery and Function

Boch, J., & Bonas, U. (2010) · Annual Review of Phytopathology · doi:10.1146/annurev-phyto-080508-081936 · Cited by 978 · see citing works

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

Shukla, V. K., Doyon, Y., Miller, J. C., DeKelver, R. C., Moehle, E. A., Worden, S. E., Mitchell, J. C., Arnold, N. L., Gopalan, S. M., Meng, X., et al. (2009) · Nature · doi:10.1038/nature07992 · Cited by 963 · see citing works

BLM–DNA2–RPA–MRN and EXO1–BLM–RPA–MRN constitute two DNA end resection machineries for human DNA break repairPreprint

Nimonkar, A. V., Genschel, J., Kinoshita, E., Polaczek, P., Campbell, J. L., Wyman, C., Modrich, P. L., & Kowalczykowski, S. C. (2011) · Genes & Development · doi:10.1101/gad.2003811 · Cited by 767 · see citing works

High-frequency modification of plant genes using engineered zinc-finger nucleases

Townsend, J. A., Wright, D. A., Winfrey, R. J., Fu, F., Maeder, M. L., Joung, J. K., & Voytas, D. F. (2009) · Nature · doi:10.1038/nature07845 · Cited by 737 · see citing works

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity

Mussolino, C., Morbitzer, R., Lütge, F., Dannemann, N., Lahaye, T., & Cathomen, T. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr597 · Cited by 714 · see citing works

Rapid “Open-Source” Engineering of Customized Zinc-Finger Nucleases for Highly Efficient Gene Modification

Maeder, M. L., Thibodeau-Beganny, S., Osiak, A., Wright, D. A., Anthony, R. M., Eichtinger, M., Jiang, T., Foley, J. E., Winfrey, R. J., Townsend, J. A., et al. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.06.016 · Cited by 708 · see citing works

Genetic manipulation of lignin reduces recalcitrance and improves ethanol production from switchgrass

Fu, C., Mielenz, J. R., Xiao, X., Ge, Y., Hamilton, C. Y., Rodríguez, M., Chen, F., Foston, M. B., Ragauskas, A. J., Bouton, J. H., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1100310108 · Cited by 654 · see citing works

Transcription Activator-Like Effector Nucleases Enable Efficient Plant Genome Engineering

Zhang, Y., Zhang, F., Li, X., Baller, J. A., Qi, Y., Starker, C. G., Bogdanove, A. J., & Voytas, D. F. (2012) · PLANT PHYSIOLOGY · doi:10.1104/pp.112.205179 · Cited by 487 · see citing works

Advancing Our Understanding and Capacity to Engineer Nature’s CO2-Sequestering Enzyme, Rubisco

Whitney, S. M., Houtz, R. L., & Alonso, H. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.164814 · Cited by 468 · see citing works

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

Pattanayak, V., Ramirez, C. L., Joung, J. K., & Liu, D. R. (2011) · Nature Methods · doi:10.1038/nmeth.1670 · Cited by 453 · see citing works

TAL effectors: finding plant genes for disease and defense

Bogdanove, A. J., Schornack, S., & Lahaye, T. (2010) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2010.04.010 · Cited by 442 · see citing works

Targeted mutagenesis using zinc-finger nucleases in Arabidopsis

Lloyd, A., Plaisier, C. L., Carroll, D., & Drews, G. N. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409339102 · Cited by 418 · see citing works

De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks

Mahfouz, M. M., Li, L., Shamimuzzaman, M., Wibowo, A. T., Fang, X., & Zhu, J. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019533108 · Cited by 417 · see citing works

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

Doyon, Y., Vo, T. D., Mendel, M. C., Greenberg, S. G., Wang, J., Xia, D. F., Miller, J. C., Urnov, F. D., Gregory, P. D., & Holmes, M. C. (2011) · Nature Methods · doi:10.1038/nmeth.1539 · Cited by 402 · see citing works

High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases

Zhang, F., Maeder, M. L., Unger‐Wallace, E., Hoshaw, J. P., Reyon, D., Christian, M. L., Li, X., Pierick, C. J., Dobbs, D. L., Peterson, T., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914991107 · Cited by 379 · see citing works

Homing Endonucleases: From Microbial Genetic Invaders to Reagents for Targeted DNA Modification

Stoddard, B. L. (2011) · Structure · doi:10.1016/j.str.2010.12.003 · Cited by 346 · see citing works

Deployment of new biotechnologies in plant breeding

Lusser, M., Parisi, C., Plan, D., & Rodríguez-Cerezo, E. (2012) · Nature Biotechnology · doi:10.1038/nbt.2142 · Cited by 342 · see citing works

Targeted gene knockout by direct delivery of zinc-finger nuclease proteins

Gaj, T., Guo, J., Kato, Y., Sirk, S. J., & Barbas, C. F. (2012) · Nature Methods · doi:10.1038/nmeth.2030 · Cited by 306 · see citing works

Site-directed mutagenesis in Arabidopsis using custom-designed zinc finger nucleases

Osakabe, K., Osakabe, Y., & Toki, S. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000234107 · Cited by 303 · see citing works

Genotoxic stress in plants: Shedding light on DNA damage, repair and DNA repair helicases

Tuteja, N. K., Ahmad, P., Panda, B. B., & Tuteja, R. (2008) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2008.06.004 · Cited by 255 · see citing works

An Induced Mutation in Tomato eIF4E Leads to Immunity to Two Potyviruses

Piron‐Prunier, F., Nicolaı̈, M., Minoïa, S., Piednoir, E., Moretti, A., Salgues, A., Zamir, D., Caranta, C., & Bendahmane, A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011313 · Cited by 245 · see citing works

Heritable targeted mutagenesis in maize using a designed endonuclease

Gao, H., Smith, J., Yang, M., Jones, S., Djukanovic, V., Nicholson, M. G., West, A., Bidney, D. L., Falco, S. C., Jantz, D., et al. (2009) · The Plant Journal · doi:10.1111/j.1365-313x.2009.04041.x · Cited by 241 · see citing works

TILLING - a shortcut in functional genomics

Kurowska, M. M., Daszkowska‐Golec, A., Gruszka, D., Marzec, M., Szurman‐Zubrzycka, M., Szarejko, I., & Małuszyński, M. (2011) · Journal of Applied Genetics · doi:10.1007/s13353-011-0061-1 · Cited by 240 · see citing works

DNA-binding Specificity Is a Major Determinant of the Activity and Toxicity of Zinc-finger Nucleases

Cornu, T. I., Thibodeau-Beganny, S., Guhl, E., Alwin, S., Eichtinger, M., Joung, J. K., & Cathomen, T. (2007) · Molecular Therapy · doi:10.1038/sj.mt.6300357 · Cited by 228 · see citing works

Targeted transgene integration in plant cells using designed zinc finger nucleases

Cai, C. Q., Doyon, Y., Ainley, W. M., Miller, J. C., DeKelver, R. C., Moehle, E. A., Rock, J. M., Lee, Y.-L., Garrison, R. J., Schulenberg, L. L., et al. (2008) · Plant Molecular Biology · doi:10.1007/s11103-008-9449-7 · Cited by 220 · see citing works

In planta gene targeting

Fauser, F., Roth, N., Pacher, M., Ilg, G., Sánchez‐Fernández, R., Biesgen, C., & Puchta, H. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1202191109 · Cited by 214 · see citing works

Repairing breaks in the plant genome: the importance of keeping it together

Waterworth, W. M., Drury, G. E., Bray, C. M., & West, C. E. (2011) · New Phytologist · doi:10.1111/j.1469-8137.2011.03926.x · Cited by 204 · see citing works

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects

Ramirez, C. L., Certo, M. T., Mussolino, C., Goodwin, M. J., Cradick, T. J., McCaffrey, A. P., Cathomen, T., Scharenberg, A. M., & Joung, J. K. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks179 · Cited by 174 · see citing works

Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleasesPreprint

Lee, H. J., Kweon, J., Kim, E., Kim, S., & Kim, J. (2011) · Genome Research · doi:10.1101/gr.129635.111 · Cited by 165 · see citing works

Recent Advances in Plant Transformation

Barampuram, S., & Zhang, Z. J. (2010) · Methods in molecular biology · doi:10.1007/978-1-61737-957-4_1 · Cited by 137 · see citing works

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzymePreprint

Wang, J., Friedman, G., Doyon, Y., Wang, N. S., Li, C. J., Miller, J. C., Hua, K. L., Yan, J. J., Babiarz, J., Gregory, P. D., et al. (2012) · Genome Research · doi:10.1101/gr.122879.111 · Cited by 135 · see citing works

Domain Swapping and Gene Shuffling Identify Sequences Required for Induction of an Avr-Dependent Hypersensitive Response by the Tomato Cf-4 and Cf-9 Proteins

Wulff, B. B. H., Thomas, C. M., Smoker, M., Grant, M., & Jones, J. D. G. (2001) · The Plant Cell · doi:10.1105/tpc.13.2.255 · Cited by 133 · see citing works

Zinc finger nuclease-mediated transgene deletion

Petolino, J. F., Worden, A., Curlee, K., Connell, J., Strange, T. L., Larsen, C., & Russell, S. M. (2010) · Plant Molecular Biology · doi:10.1007/s11103-010-9641-4 · Cited by 128 · see citing works

Genome Engineering of Crops with Designer Nucleases

Curtin, S. J., Voytas, D. F., & Stupar, R. M. (2012) · The Plant Genome · doi:10.3835/plantgenome2012.06.0008 · Cited by 124 · see citing works

Homing endonucleases: DNA scissors on a mission

Hafez, M., & Hausner, G. (2012) · Genome · doi:10.1139/g2012-049 · Cited by 122 · see citing works

Colinearity and Similar Expression Pattern of Rice DREB1s Reveal Their Functional Conservation in the Cold-Responsive Pathway

Mao, D., & Chen, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047275 · Cited by 119 · see citing works

Scientific opinion addressing the safety assessment of plants developed using Zinc Finger Nuclease 3 and other Site‐Directed Nucleases with similar function

(GMO), E. P. O. G. M. O. (2012) · EFSA Journal · doi:10.2903/j.efsa.2012.2943 · Cited by 117 · see citing works

The I-CreI meganuclease and its engineered derivatives: applications from cell modification to gene therapy

Arnould, S., Delenda, C., Grizot, S., Desseaux, C., Pâques, F., Silva, G. H., & Smith, J. (2010) · Protein Engineering Design and Selection · doi:10.1093/protein/gzq083 · Cited by 112 · see citing works

Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion

Şöllü, C., Pars, K., Cornu, T. I., Thibodeau-Beganny, S., Maeder, M. L., Joung, J. K., Heilbronn, R., & Cathomen, T. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq720 · Cited by 109 · see citing works

ZFN‐induced mutagenesis and gene‐targeting in Arabidopsis through Agrobacterium‐mediated floral dip transformation

de Pater, S., Neuteboom, L. W., Pinas, J. E., Hooykaas, P. J. J., & van der Zaal, B. J. (2009) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2009.00446.x · Cited by 103 · see citing works

Homologous recombination: a basis for targeted genome optimization in crop species such as maize

D’Halluin, K., Vanderstraeten, C., Stals, E., Cornelissen, M., & Ruiter, R. K. (2007) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2007.00305.x · Cited by 99 · see citing works

Move over ZFNs

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Scientific opinion addressing the safety assessment of plants developed using Zinc Finger Nuclease 3 and other site-directed Nucleases with similar function

Arpaia, S., Birch, A. N., Chesson, A., du Jardin, P., Gathmann, A., Gropp, J., Herman, L., Hoen-Sorteberg, H.-G., Jones, H. D., Kiss, J. G., et al. (2012) · Zurich Open Repository and Archive (University of Zurich) · doi:10.5167/uzh-75266 · Cited by 94 · see citing works

Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining.

Grabarz, A., Barascu, A., Guirouilh‐Barbat, J., & López, B. S. (2012) · Europe PMC (PubMed Central) · Cited by 93 · see citing works

Identification and characterisation of seed storage protein transcripts from Lupinus angustifolius

Foley, R. C., Gao, L., Spriggs, A., Soo, L. Y. C., Goggin, D. E., Smith, P. M. C., Atkins, C. A., & Singh, K. B. (2011) · BMC Plant Biology · doi:10.1186/1471-2229-11-59 · Cited by 90 · see citing works

Genome-Wide Analysis of Fatty Acid Desaturases in Soybean (Glycine max)

Chi, X., Yang, Q., Lu, Y., Wang, J., Zhang, Q., Pan, L., Chen, M., He, Y., & Yu, S. (2011) · Plant Molecular Biology Reporter · doi:10.1007/s11105-010-0284-z · Cited by 87 · see citing works

Herbicides, Theory and Applications

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Tiptoeing around transgenics

Waltz, E. (2012) · Nature Biotechnology · doi:10.1038/nbt.2143 · Cited by 82 · see citing works

Lack of starch synthase IIIa and high expression of granule-bound starch synthase I synergistically increase the apparent amylose content in rice endosperm

Crofts, N., Abe, K., Aihara, S., Itoh, R., Nakamura, Y., Itoh, K., & Fujita, N. (2012) · Plant Science · doi:10.1016/j.plantsci.2012.05.006 · Cited by 79 · see citing works

A toolbox and procedural notes for characterizing novel zinc finger nucleases for genome editing in plant cells

Tovkach, A., Zeevi, V., & Tzfira, T. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03718.x · Cited by 76 · see citing works

The requirement for recombination factors differs considerably between different pathways of homologous double‐strand break repair in somatic plant cells

Roth, N., Klimesch, J., Dukowic‐Schulze, S., Pacher, M., Mannuß, A., & Puchta, H. (2012) · The Plant Journal · doi:10.1111/j.1365-313x.2012.05119.x · Cited by 72 · see citing works

Genome modifications in plant cells by custom‐made restriction enzymes

Tzfira, T., Weinthal, D., Marton, I., Zeevi, V., Zuker, A., & Vainstein, A. (2012) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2011.00672.x · Cited by 68 · see citing works

Suitability of Molecular Markers for Selection of Potatoes Resistant to Globodera spp

Milczarek, D., Flis, B., & Przetakiewicz, A. (2011) · American Journal of Potato Research · doi:10.1007/s12230-011-9189-0 · Cited by 68 · see citing works

Inside the CBF locus in Poaceae

Tondelli, A., Francia, E., Barabaschi, D., Pasquariello, M., & Pecchioni, N. (2010) · Plant Science · doi:10.1016/j.plantsci.2010.08.012 · Cited by 67 · see citing works

Localized egg‐cell expression of effector proteins for targeted modification of the Arabidopsis genome

Even‐Faitelson, L., Samach, A., Melamed‐Bessudo, C., Avivi‐Ragolsky, N., & Levy, A. A. (2011) · The Plant Journal · doi:10.1111/j.1365-313x.2011.04741.x · Cited by 64 · see citing works

Generation of redesigned homing endonucleases comprising DNA-binding domains derived from two different scaffolds

Grizot, S., Epinat, J.-C., Thomas, S., Duclert, A., Rolland, S., Pâques, F., & Duchateau, P. N. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp1171 · Cited by 63 · see citing works

Duplication of a well-conserved homeodomain-leucine zipper transcription factor gene in barley generates a copy with more specific functions

Sakuma, S., Pourkheirandish, M., Matsumoto, T., Koba, T., & Komatsuda, T. (2009) · Functional & Integrative Genomics · doi:10.1007/s10142-009-0134-y · Cited by 54 · see citing works

LAHEDES: the LAGLIDADG homing endonuclease database and engineering server

Taylor, G. K., Petrucci, L. H., Lambert, A. R., Baxter, S. K., Jarjour, J., & Stoddard, B. L. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks365 · Cited by 51 · see citing works

The twenty-first century, the century of plant breeding

Stamp, P., & Visser, R. G. F. (2012) · Euphytica · doi:10.1007/s10681-012-0743-8 · Cited by 48 · see citing works

Studies on rice seed quality through analysis of a large-scale T-DNA insertion population

Fu, F., Ye, R., Xu, S., & Xue, H. (2009) · Cell Research · doi:10.1038/cr.2009.15 · Cited by 40 · see citing works

Creating highly specific nucleases by fusion of active restriction endonucleases and catalytically inactive homing endonucleases

Fonfara, I., Curth, U., Pingoud, A. M., & Wende, W. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr788 · Cited by 32 · see citing works

Permanent genome modifications in plant cells by transient viral vectors

Vainstein, A., Marton, I., Zuker, A., Danziger, M., & Tzfira, T. (2011) · Trends in biotechnology · doi:10.1016/j.tibtech.2011.03.007 · Cited by 28 · see citing works

Plant Chromosome Engineering

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Functional characterization of the Gentiana lutea zeaxanthin epoxidase (GlZEP) promoter in transgenic tomato plants

Yang, Q., Yuan, D., Shi, L., Capell, T., Bai, C., Nuan, W., Lü, X., Sandmann, G., Christou, P., & Zhu, C. (2012) · Transgenic Research · doi:10.1007/s11248-012-9591-5 · Cited by 15 · see citing works

Analysing patent landscapes in plant biotechnology and new plant breeding techniques

Parisi, C. M., Rodríguez‐Cerezo, E., & Thangaraj, H. S. (2012) · Transgenic Research · doi:10.1007/s11248-012-9641-z · Cited by 14 · see citing works

An Industry Perspective of All-native and Transgenic Potatoes

Toevs, E. A., Guenthner, J. F., Johnson, A. J., McIntosh, C. S., & Thornton, M. K. (2011) · MOspace Institutional Repository (University of Missouri) · Cited by 13 · see citing works

Unusual Case of Apparent Hypermutation in Arabidopsis thaliana

Sasaki, T., Naumann, U., Forai, P., Matzke, A. J. M., & Matzke, M. A. (2012) · Genetics · doi:10.1534/genetics.112.144634 · Cited by 9 · see citing works

Decreasing erucic acid level by RNAi-mediated silencing of fatty acid elongase 1 (BnFAE1.1) in rapeseeds (Brassica napus L.)

Tian, B., Wei, F., Shu, H., Zhang, Q., Zang, X., & Lian, Y. (2011) · AFRICAN JOURNAL OF BIOTECHNOLOGY · Cited by 6 · see citing works

Isolation of fruit ripening genes from Carica papaya var. Eksotika I cDNA libraries.

Yun, S., Johari, S. A., Maheswary, V., & Kalsom, A. (2011) · Simulating the effects of changing planting date towards rice production in MADA area Malaysia · Cited by 4 · see citing works

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

Kim, S., Kim, D., Cho, S. W., Kim, J., & Kim, J.-S. (2014) · Genome Research · doi:10.1101/gr.171322.113 · Cited by 1,856 · see citing works

The CRISPR/Cas9 system for plant genome editing and beyond

Bortesi, L., & Fischer, R. (2014) · Biotechnology Advances · doi:10.1016/j.biotechadv.2014.12.006 · Cited by 1,234 · see citing works

Editing plant genomes with CRISPR/Cas9

Belhaj, K., Chaparro‐Garcia, A., Kamoun, S., Patron, N. J., & Nekrasov, V. (2014) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2014.11.007 · Cited by 541 · see citing works

Global Regulation of Genetically Modified Crops Amid the Gene Edited Crop Boom – A Review

Turnbull, C., Lillemo, M., & Hvoslef‐Eide, A. K. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.630396 · Cited by 479 · see citing works

The Regulatory Status of Genome‐edited Crops

Wolt, J. D., Wang, K., & Yang, B. (2015) · Plant Biotechnology Journal · doi:10.1111/pbi.12444 · Cited by 292 · see citing works

Precise plant breeding using new genome editing techniques: opportunities, safety and regulation in the <scp>EU</scp>

Hartung, F., & Schiemann, J. (2014) · The Plant Journal · doi:10.1111/tpj.12413 · Cited by 277 · see citing works

Transient plant transformation mediated by Agrobacterium tumefaciens: Principles, methods and applications

Křenek, P., Šamajová, O., Luptovčiak, I., Doskočilová, A., Komis, G., & Šamaj, J. (2015) · Biotechnology Advances · doi:10.1016/j.biotechadv.2015.03.012 · Cited by 260 · see citing works

MicroRNA‐Based Biotechnology for Plant Improvement

Zhang, B., & Wang, Q. (2014) · Journal of Cellular Physiology · doi:10.1002/jcp.24685 · Cited by 228 · see citing works

Plant Genome Engineering for Targeted Improvement of Crop Traits

Sedeek, K. E. M., Mahas, A., & Mahfouz, M. M. (2019) · Frontiers in Plant Science · doi:10.3389/fpls.2019.00114 · Cited by 232 · see citing works

Phaeodactylum tricornutum: A Diatom Cell Factory

Butler, T. O., Kapoore, R. V., & Vaidyanathan, S. (2020) · Trends in biotechnology · doi:10.1016/j.tibtech.2019.12.023 · Cited by 212 · see citing works

Genetically engineered crops for sustainably enhanced food production systems

Aziz, M. A., Brini, F., Rouached, H., & Masmoudi, K. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.1027828 · Cited by 192 · see citing works

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