The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
The zebrafish as a model for complex tissue regeneration
Open accessAbstract
For centuries, philosophers and scientists have been fascinated by the principles and implications of regeneration in lower vertebrate species. Two features have made zebrafish an informative model system for determining mechanisms of regenerative events. First, they are highly regenerative, able to regrow amputated fins, as well as a lesioned brain, retina, spinal cord, heart, and other tissues. Second, they are amenable to both forward and reverse genetic approaches, with a research toolset regularly updated by an expanding community of zebrafish researchers. Zebrafish studies have helped identify new mechanistic underpinnings of regeneration in multiple tissues, and in some cases have served as a guide for contemplating regenerative strategies in mammals. Here, we review the recent history of zebrafish as a genetic model system for understanding how and why tissue regeneration occurs.
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Citations
Cites
Efficient genome editing in zebrafish using a CRISPR-Cas system
Hwang, W. Y., Fu, Y., Reyon, D., Maeder, M. L., Tsai, S. Q., Sander, J. D., Peterson, R. T., Yeh, J.-R. J., & Joung, J. K. (2013) · Nature Biotechnology · doi:10.1038/nbt.2501 · Cited by 2,937
Transient Regenerative Potential of the Neonatal Mouse Heart
Porrello, E. R., Mahmoud, A. I., Simpson, E., Hill, J. A., Richardson, J. A., Olson, E. N., & Sadek, H. A. (2011) · Science · doi:10.1126/science.1200708 · Cited by 2,545
Mammalian heart renewal by pre-existing cardiomyocytes
Senyo, S. E., Steinhauser, M. L., Pizzimenti, C. L., Yang, V. K., Cai, L., Wang, M., Wu, T.-D., Guerquin-Kern, J.-L., Lechene, C. P., & Lee, R. T. (2013) · Nature · doi:10.1038/nature11682 · Cited by 1,343
Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
Jopling, C., Sleep, E., Raya, M., Martí, M., Raya, A., & Belmonte, J. C. I. (2010) · Nature · doi:10.1038/nature08899 · Cited by 1,333
Functional screening identifies miRNAs inducing cardiac regeneration
Eulalio, A., Mano, M., Ferro, M. D., Zentilin, L., Sinagra, G., Zacchigna, S., & Giacca, M. (2012) · Nature · doi:10.1038/nature11739 · Cited by 1,029
Bernardos, R. L., Barthel, L. K., Meyers, J. R., & Raymond, P. A. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1624-07.2007 · Cited by 647
Wnt signaling promotes regeneration in the retina of adult mammals
Osakada, F., Ooto, S., Akagi, T., Mandai, M., Akaike, A., & Takahashi, M. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.4193-06.2007 · Cited by 322
Regeneration of inner retinal neurons after intravitreal injection of ouabain in zebrafish
Fimbel, S. M., Montgomery, J. E., Burket, C. T., & Hyde, D. R. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.5317-06.2007 · Cited by 298
Self-citationHB-EGF is Necessary and Sufficient for Müller Glia Dedifferentiation and Retina Regeneration
Wan, J., Ramachandran, R., & Goldman, D. (2012) · Developmental Cell · doi:10.1016/j.devcel.2011.11.020 · Cited by 262 · cited 3×
“Other candidate molecules that appear to stimulate Müller glia proliferation in the zebrafish retina include Heparin-binding-Epidermal Growth Factor (HB-EGF) [113], Insulinoma associated 1a (Insm1a) [104], ADP [114], and free radicals [98], suggesting a possibly complicated process for full activation of regeneration.”
BackgroundSEGREGATION ANALYSES AND GENE-CENTROMERE DISTANCES IN ZEBRAFISH
Streisinger, G., Singer, F., Walker, C., Knauber, D., & Dower, N. (1986) · Genetics · doi:10.1093/genetics/112.2.311 · Cited by 245
Cited by
Changes in Regenerative Capacity through Lifespan
Yun, M. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms161025392 · Cited by 216
TNF signaling and macrophages govern fin regeneration in zebrafish larvae
Nguyen-Chi, M., Laplace-Builhé, B., Travnickova, J., Luz-Crawford, P., Tejedor, G., Lutfalla, G., Kissa, K., Jorgensen, C., & Djouad, F. (2017) · Cell Death & Disease · doi:10.1038/cddis.2017.374 · Cited by 190
Stückemann, T., Cleland, J. P., Werner, S., Thi-Kim Vu, H., Bayersdorf, R., Liu, S.-Y., Friedrich, B., Jülicher, F., & Rink, J. C. (2017) · Developmental Cell · doi:10.1016/j.devcel.2016.12.024 · Cited by 133
Myelin replacement triggered by single-cell demyelination in mouse cortex
Snaidero, N., Schifferer, M., Mezydlo, A., Zalc, B., Kerschensteiner, M., & Misgeld, T. (2020) · Nature Communications · doi:10.1038/s41467-020-18632-0 · Cited by 63
Pericytes: Problems and Promises for CNS Repair
Laredo, F., Plebanski, J., & Tedeschi, A. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00546 · Cited by 44
“Unlike mammals, lower vertebrate species such as zebrafish retain the ability to regenerate injured tissues including the brain, retina and spinal cord (Gemberling et al., 2013; Rasmussen and Sagasti, 2017).”
BackgroundLongitudinal in vivo imaging of adult Danionella cerebrum using standard confocal microscopy
Lam, P.-Y. (2022) · Disease Models & Mechanisms · doi:10.1242/dmm.049753 · Cited by 33
Regulation of genomic output and (pluri)potency in regeneration
Duncan, E. M., & Sánchez Alvarado, A. (2019) · Annual Review of Genetics · doi:10.1146/annurev-genet-112618-043733 · Cited by 17
Metadata
- Authors
- Gemberling, M., Bailey, T. J., Hyde, D. R., & Poss, K. D.
- Venue
- Trends in Genetics
- Publisher
- Elsevier BV
- Published
- 2013-11
- Volume
- 29
- Issue
- 11
- Pages
- 611-620
- ISSN
- 0168-9525 (ISSN-L)
- OpenAlex
- W1992663358
- Cited by
- 566
- References
- 13
- FWCI
- 3.85
- Type
- journal article
- Language
- en
- Open access
- green
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