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HPV16 E6 augments Wnt signaling in an E6AP-dependent manner
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“the nuclear accumulation of β-catenin has been shown to be associated with E6 in activation of the Wnt pathway. The mechanism is dependent on E6’s ability to interact with E6AP and independent of E6’s ability to target p53 for degradation or to bind to the PDZ-containing E6 targets [234]”
From The Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis (2021) · cites this paper as [234]
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Cites
Zebrafish Prickle, a Modulator of Noncanonical Wnt/Fz Signaling, Regulates Gastrulation Movements
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Cited by
Basukala, O., & Banks, L. (2021) · Viruses · doi:10.3390/v13101892 · Cited by 137
Metadata
- Authors
- Lichtig, H., Gilboa, D. A., Jackman, A., Gonen, P., Levav-Cohen, Y., Haupt, Y., & Sherman, L.
- Venue
- Virology
- Publisher
- Elsevier BV
- Published
- 2010-01
- Volume
- 396
- Issue
- 1
- Pages
- 47-58
- ISSN
- 0042-6822
- Cited by
- 61
- References
- 3
- Language
- en
- Licence
- Funders
- Leo Minz Fund for Cancer Research, Tel-Aviv University and the Cooperation Program in Cancer Research of the Deutsches Krebsforschungszentrum (DKFZ) and Israel's Ministry of Sciences and Technology (MOST) (1841)
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