Lactation and cardiovascular risk factors in mothers in a population-based study: the HUNT-study
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BACKGROUND: Lactation has beneficial short term effects on maternal metabolic health, but the long term effects are less well known. METHODS: We studied the association between lifetime duration of lactation and cardiovascular risk factors in mothers later in life among 21,368 parous women aged 20 to 85 years attending the second Nord-Trøndelag Health Study (HUNT2) in 1995-1997, Norway, a cross-sectional population-based study. General linear modelling was used to calculate mean values of known cardiovascular risk factor levels in five categories of lifetime duration of lactation. Logistic regression was conducted to estimate odds ratios of hypertension, obesity and diabetes. RESULTS: Among women aged 50 years or younger, lifetime duration of lactation was significantly and inversely associated with body mass index (P-trend, < 0.001), waist circumference (P-trend, < 0.001), systolic and diastolic blood pressure (both P-trends, < 0.001), and serum levels of triglycerides, total cholesterol and low density lipoprotein cholesterol (all P-trends, < 0.001) after adjustment for covariates. Parous women aged 50 years or younger who had never lactated had higher prevalence of hypertension, obesity and diabetes. In this age group, compared to women who had lactated for 24 months or more, parous women who had never lactated had an OR for hypertension of 1.88 (95% CI 1.41, 2.51), an OR for obesity of 3.37 (95% CI 2.51, 4.51) and an OR for diabetes of 5.87 (95% CI 2.25, 15.3). Among women older than 50 years there were no clear associations. CONCLUSION: Lifetime duration of lactation was associated with long term reduced cardiovascular risk levels in mothers aged 50 years or younger.
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In young women aged 50 or younger, prolonged lactation was inversely linked to risk factors for cardiovascular disease, including total cholesterol, body mass index, waist circumference, and hypertension.
“in young women aged 50 or younger, prolonged lactation was inversely linked to risk factors for cardiovascular disease, including total cholesterol, body mass index, waist circumference, and hypertension”
From Association between the reproductive health of young women and cardiovascular disease in later life: umbrella review (2020) · cites this paper as [146]
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Self-citation
- Authors
- Natland, S. T., Nilsen, T. I. L., Midthjell, K., Andersen, L. F., & Forsmo, S.
- Affiliations
- Norwegian University of Science and Technology (NO)
- University of Oslo (NO)
- Venue
- International Breastfeeding Journal
- Published
- 2012-06
- Volume
- 7
- Issue
- 1
- Pages
- 8-8
- ISSN
- 1746-4358 (ISSN-L)
- PMC
- PMC3489591
- OpenAlex
- W2119581008
- Cited by
- 80
- References
- 53
- Citations by year
- 2025: 6 · 2024: 1 · 2023: 7 · 2022: 5 · 2021: 6 · 2020: 7 · 2019: 6 · 2018: 9 · 2017: 7 · 2016: 5 · 2015: 10 · 2014: 4 · 2013: 4 · 2012: 3
- FWCI
- 5.03
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Breastfeeding Journal (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- NORA - Norwegian Open Research Archives (submittedVersion, cc-by)
- Funders
- Norges Teknisk-Naturvitenskapelige Universitet
- Helse Midt-Norge
- Norwegian Institute of Public Health
- Topics
- Health Sciences › Medicine › Epidemiology › Breastfeeding Practices and Influences
- Health Sciences › Medicine › Oncology › Cancer Risks and Factors
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Keywords
- lactation length, cardiovascular risk factors, maternal health, hypertension, obesity, diabetes mellitus, body mass index, waist circumference, blood pressure, serum lipids, postmenopausal women
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