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Cited by 552

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Abnormal T-Cell Reactivity against Paternal Antigens in Spontaneous Abortion

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Zenclussen, Ana Claudia, Gerlof, Katrin, Zenclussen, Maria Laura, Sollwedel, André, Bertoja, Annarosa Zambon, Ritter, Thomas, Kotsch, Katja, Leber, Joachim, Volk, Hans-Dieter·2005·The American Journal of Pathology
DOI 10.1016/s0002-9440(10)62302-4
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  1. Medawar, 1953, Some immunological and endocrinological problems raised by the evolution of viviparity in vertebrates, Symp Soc Exp Biol, 44, 320
  2. Tafuri, 1995, T cell awareness of paternal alloantigens during pregnancy, Science, 270, 630, 10.1126/science.270.5236.630 · DOI · Paper page
  3. Munn, 1998, Prevention of allogeneic fetal rejection by tryptophan catabolism, Science, 281, 1191, 10.1126/science.281.5380.1191 · DOI · Paper page
  4. Rouas-Freiss, 1997, Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis, Proc Natl Acad Sci USA, 94, 11520, 10.1073/pnas.94.21.11520 · DOI · Paper page
  5. Makriagiannis, 2001, Corticotropin-releasing hormone promotes blastocytes implantation and early maternal tolerance, Nat Immunol, 18, 367
  6. Lin, 1993, Synthesis of T helper 2-type cytokines at the feto-maternal interface, J Immunol, 151, 4562, 10.4049/jimmunol.151.9.4562 · DOI · Paper page
  7. Raghupathy, 1997, Th1-type immunity is incompatible with successful pregnancy, Immunol Today, 18, 478, 10.1016/S0167-5699(97)01127-4 · DOI · Paper page
  8. Raghupathy, 1999, Maternal Th1- and Th2-type reactivity to placental antigens in normal human pregnancy and unexplained recurrent spontaneous abortions, Cell Immunol, 196, 122, 10.1006/cimm.1999.1532 · DOI · Paper page
  9. Clark, 1999, Why did your mother reject you? Immunogenetic determinants of the response environmental selective pressure expressed at the uterine level, Am J Reprod Immunol, 41, 5, 10.1111/j.1600-0897.1999.tb00071.x · DOI · Paper page
  10. Saito, 2001, Cytokine network at the feto-maternal interface, J Reprod Immunol, 47, 87, 10.1016/S0165-0378(00)00060-7 · DOI · Paper page
  11. Piccinni, 1998, Defective production of both, leukemia inhibitor factor and type 2 T-helper cytokines by decidual T cells in unexplained recurrent abortions, Nat Med, 4, 1020, 10.1038/2006 · DOI · Paper page
  12. Joachim, 2003, The progesterone derivative dydrogesterone abrogates murine stress triggered abortion by inducing a Th2 biased local immune response, Steroids, 68, 931, 10.1016/j.steroids.2003.08.010 · DOI
  13. Krishnan, 1996, T helper-1 response against Leishmania major in pregnancy C57BL/6 mice increases implantation failure and fetal resorptions. Correlation with increased IFN-gamma and TNF-alpha and reduced IL-10 production by placenta cells, J Immunol, 15, 653, 10.4049/jimmunol.156.2.653 · DOI · Paper page
  14. Joachim, 1999, Murine stress-triggered abortion is mediated by increase of CD8+ TNF-alpha+ decidual cells via substance P, Am J Reprod Immunol, 45, 303, 10.1111/j.8755-8920.2001.450506.x · DOI
  15. Zenclussen, 2000, Interleukin-6 and soluble interleukin-6 receptor serum levels in recurrent spontaneous abortion women immunized with paternal white cells, Am J Reprod Immunol, 44, 22, 10.1111/j.8755-8920.2000.440104.x · doi:10.1111/j.8755-8920.2000.440104.x
  16. Zenclussen, 2001, Upregulation of decidual P-selection expression is associated with an increased number of Th1 cell populations in patients suffering from spontaneous abortion, Cell Immunol, 213, 94, 10.1006/cimm.2001.1877 · DOI
  17. Zenclussen, 2003, Murine abortion is associated with enhanced interleukin-6 levels at the feto-maternal interface, Cytokine, 24, 150, 10.1016/j.cyto.2003.08.002 · DOI
  18. Svensson, 2001, The Th2 cytokines IL-4 and IL-10 are not crucial for the completion of allogeneic pregnancy in mice, J Reprod Immunol, 51, 3, 10.1016/S0165-0378(01)00065-1 · DOI
  19. Margni, 2001, During pregnancy, in the context of a Th2 type cytokine prolife, serum IL-6 levels might condition the quality of the synthesized antibodies, Am J Reprod Immunol, 46, 181, 10.1034/j.1600-0897.2001.d01-1.x · doi:10.1034/j.1600-0897.2001.d01-1.x
  20. Chaouat, 2002, A brief review of recent data on some cytokine expressions at the materno-foetal interface which might challenge the classical Th1/Th2 dichotomy, J Reprod Immunol, 53, 241, 10.1016/S0165-0378(01)00119-X · DOI · Paper page
  21. Zenclussen, 2002, Questioning the Th1/Th2 paradigm in reproduction: peripheral levels of IL-12 are down-regulated in miscarriage patients, Am J Reprod Immunol, 48, 245, 10.1034/j.1600-0897.2002.01136.x · DOI
  22. Li, 1998, IL-2 and IL-4 double knockout mice reject islet allografts: a role for novel T cell growth factors in allograft rejection, J Immunol, 161, 890, 10.4049/jimmunol.161.2.890 · DOI
  23. Wood, 2003, Regulatory T cells in transplantation tolerance, Nat Rev Immunol, 3, 199, 10.1038/nri1027 · DOI · Paper page
  24. Waldmann, 2004, Regulatory T cells and organ transplantation, Semin Immunol, 16, 119, 10.1016/j.smim.2003.12.007 · DOI · Paper page
  25. Sakaguchi, 2004, Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses, Annu Rev Immunol, 22, 531, 10.1146/annurev.immunol.21.120601.141122 · DOI · Paper page
  26. Kingsley, 2002, CD25+CD4+ regulatory T cells prevent graft rejection: cTLA4- and IL-10-dependent immunoregulation of alloresponses, J Immunol, 168, 1080, 10.4049/jimmunol.168.3.1080 · DOI · Paper page
  27. Kurita, 2001, Regulation of progesterone receptors and decidualization in uterine stroma of the estrogen-receptor-alpha knock out mouse, Biol Reprod, 64, 272, 10.1095/biolreprod64.1.272 · DOI
  28. Clark, 1980, Impairment of graft versus host reaction in pregnant mice: II) selective suppression of cytotoxic cell generation correlates with soluble suppressor activity and with successful allogeneic pregnancy, Cell Immunol, 52, 106, 10.1016/0008-8749(80)90404-9 · doi:10.1016/0008-8749(80)90404-9
  29. Mellor, 2001, Extinguishing maternal immune responses during pregnancy: implications for immunosuppression, Semin Immunol, 13, 213, 10.1006/smim.2000.0317 · DOI
  30. Chaouat, 1995, IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect on IL-10 production in this abortion combination is corrected in vivo injection of IFN-τ, Am J Reprod Immunol, 154, 4261
  31. Chaouat, 1999, Localization of the Th2 cytokines IL-3, IL-4, IL-10 at the fetomaternal interface during human and murine pregnancy and lack of requirement for Fas/Fas ligand interaction for a successful allogeneic pregnancy, Am J Reprod Immunol, 42, 1, 10.1111/j.1600-0897.1999.tb00459.x · DOI
  32. Dealtry, 2000, The Th2 cytokine environment of the placenta, Int Arch Allergy Immunol, 123, 107, 10.1159/000024441 · DOI
  33. Clark, 1990, Murine pregnancy decidua produces a unique immunosuppressive molecule related to transforming growth factor beta-2, J Immunol, 144, 3008, 10.4049/jimmunol.144.8.3008 · doi:10.4049/jimmunol.144.8.3008
  34. Gorivodsky, 1999, TGF beta 2 mRNA expression and pregnancy failure in mice, Am J Reprod Immunol, 42, 124, 10.1111/j.1600-0897.1999.tb00476.x · DOI
  35. Dünker, 2002, TGF-β2−/− and 3−/− double knockout mice display severe midline fusion defects and early embryonic lethality, Anat Embryol, 206, 73, 10.1007/s00429-002-0273-6 · DOI
  36. White, 2004, Effect of interleukin-10 null mutation on maternal immune response and reproductive outcome in mice, Biol Reprod, 70, 123, 10.1095/biolreprod.103.018754 · DOI
  37. Tangri, 1994, Maternal anti-placental reactivity in natural immunologically-mediated fetal resorptions, J Immunol, 152, 4903, 10.4049/jimmunol.152.10.4903 · DOI
  38. Zelenika, 2001, The role of CD4+ T-cell subsets in determining transplantation rejection or tolerance, Immunol Rev, 182, 164, 10.1034/j.1600-065X.2001.1820113.x · DOI
  39. Hall, 1990, Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine. III. Further characterization of the CD4+ suppressor cell and its mechanisms of action, J Exp Med, 171, 141, 10.1084/jem.171.1.141 · DOI · Paper page
  40. Cosmi, 2004, Th2 cells are less susceptible than Th1 cells to the suppressive activity of CD25+ regulatory thymocytes because of their responsiveness to different cytokines, Blood, 103, 3117, 10.1182/blood-2003-09-3302 · DOI · Paper page
  41. Maloy, 2001, Regulatory T cells in the control of immune pathology, Nat Immunol, 2, 816, 10.1038/ni0901-816 · DOI · Paper page
  42. Ke, 2000, Regulatory cells potentiate the efficacy of IL4 gene transfer by upregulating Th2-dependent expression of protective molecules in the infectious tolerance pathway in transplant recipients, J Immunol, 164, 5739, 10.4049/jimmunol.164.11.5739 · DOI
  43. Aluvihare, 2004, Regulatory T cells mediate maternal tolerance to the fetus, Nat Immunol, 3, 266, 10.1038/ni1037 · DOI · Paper page
  44. Somerset, 2004, Normal human pregnancy is associated with an elevation in the immune suppressive CD25+ CD4+ regulatory T-cell subset, Immunology, 112, 38, 10.1111/j.1365-2567.2004.01869.x · DOI · Paper page
  45. Sasaki, 2004, Decidual and peripheral blood CD4+CD25+ regulatory T cells in early pregnancy subjects and spontaneous abortion cases, Mol Hum Reprod, 10, 347, 10.1093/molehr/gah044 · DOI · Paper page
  46. Savion, 1995, Pregnancy-associated effect on mouse thymocytes in vitro, Cell Immunol, 162, 282, 10.1006/cimm.1995.1080 · doi:10.1006/cimm.1995.1080
  47. Phuc, 1981, Thymic involution in pregnant mice. I. Characterization of the remaining thymocyte subpopulations, Clin Exp Immunol, 44, 247
  48. Phuc, 1981, Thymic involution in pregnant mice. II. Functional aspects of the remaining thymocytes, Clin Exp Immunol, 44, 253
  49. Clarke, 1989, Histological changes in the thymus during mouse pregnancy, Thymus, 14, 65
  50. Clarke, 1994, The effects of pregnancy on the mouse thymic epithelium, Cell Tissue Res, 275, 309, 10.1007/BF00319429 · doi:10.1007/bf00319429
  51. Chaouat, 1983, The murine placenta as an immunological barrier between the mother and the fetus, Immunol Rev, 75, 31, 10.1111/j.1600-065X.1983.tb01090.x · doi:10.1111/j.1600-065x.1983.tb01090.x
  52. Kirby, 1964, Antigen barrier of the mouse placenta, Nature, 204, 548, 10.1038/204548a0 · DOI · Paper page
  53. Billington, 1992, The normal fetomaternal immune relationship, Baillieres Clin Obstet Gynaecol, 6, 417, 10.1016/S0950-3552(05)80004-5 · DOI
  54. Smith, 1977, The adoptive transfer of pregnancy-induced unresponsiveness to male skin grafts with thymus-dependent cells, J Exp Med, 146, 899, 10.1084/jem.146.3.899 · doi:10.1084/jem.146.3.899
  55. Taylor, 2001, CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade, J Exp Med, 193, 1311, 10.1084/jem.193.11.1311 · DOI · Paper page
  56. Hara, 2001, IL-10 is required for regulatory cells to mediate tolerance to alloantigens in vivo, J Immunol, 166, 3789, 10.4049/jimmunol.166.6.3789 · DOI · Paper page
  57. Kupiec-Weglinski, 1998, The “infectious” tolerance pathway in organ allograft recipients, Transplant Proc, 4, 1595, 10.1016/S0041-1345(98)00365-0 · doi:10.1016/s0041-1345(98)00365-0
  58. Chaouat, 1983, Vaccination against spontaneous abortion in mice, J Reprod Immunol, 5, 389, 10.1016/0165-0378(83)90248-6 · doi:10.1016/0165-0378(83)90248-6
  59. Erlebacher, 2004, Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system, J Clin Invest, 114, 39, 10.1172/JCI200420645 · doi:10.1172/jci200420645

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Metadata

Authors
Zenclussen, A. C., Gerlof, K., Zenclussen, M. L., Sollwedel, A., Bertoja, A. Z., Ritter, T., Kotsch, K., Leber, J., & Volk, H.-D.
Venue
The American Journal of Pathology
Publisher
Elsevier BV
Published
2005-03
Volume
166
Issue
3
Pages
811-822
ISSN
0002-9440 (ISSN-L)
DOI
10.1016/s0002-9440(10)62302-4
OpenAlex
W2153095488
Cited by
552
References
1
FWCI
7.83
Type
journal article
Language
en
Open access
bronze
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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CoChat. (2026). Citation check: Abnormal T-Cell Reactivity against Paternal Antigens in Spontaneous Abortion. https://app.cochat.ai/papers/10.1016/s0002-9440(10)62302-4
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Zenclussen, A. C., Gerlof, K., Zenclussen, M. L., Sollwedel, A., Bertoja, A. Z., Ritter, T., Kotsch, K., Leber, J., & Volk, H.-D. (2005). Abnormal T-Cell Reactivity against Paternal Antigens in Spontaneous Abortion. The American Journal of Pathology. https://doi.org/10.1016/s0002-9440(10)62302-4

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