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Ten Years Progress of Electrical Detection of Heavy Metal Ions (HMIs) Using Various Field-Effect Transistor (FET) Nanosensors: A Review

Falina, S., Syamsul, M., Rhaffor, N. A., Hamid, S. S., Zain, K. A. M., Manaf, A. A., & Kawarada, H. (2021) · Biosensors · doi:10.3390/bios11120478 · Cited by 61 · see citing works

Synthesis and biological activity evaluation of hydrazone derivatives based on a Tröger’s base skeleton

Kaplánek, R., Havlík, M., Dolenský, B., Rak, J., Džubák, P., Konečný, P., Hajdúch, M., Králová, J., & Král, V. (2015) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2015.01.029 · Cited by 60 · see citing works

New insights on vanadium binding to human serum transferrin

Pessoa, J. C., Gonçalves, G., Roy, S., Correia, I., Mehtab, S., Santos, M. F. A., & Santos‐Silva, T. (2013) · Inorganica Chimica Acta · doi:10.1016/j.ica.2013.11.025 · Cited by 59 · see citing works

Caffeine–hydrazones as anticancer agents with pronounced selectivity toward T-lymphoblastic leukaemia cells

Kaplánek, R., Jakubek, M., Rak, J., Kejík, Z., Havlík, M., Dolenský, B., Frydrych, I., Hajdúch, M., Kolář, M., Bogdanová, K., et al. (2015) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2015.03.003 · Cited by 56 · see citing works

Addressing selectivity criteria in binding equilibria

Bazzicalupi, C., Bianchi, A., Giorgi, C., Clares, M. P., & García‐España, E. (2011) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2011.05.013 · Cited by 55 · see citing works

Hydroxypyridinone-Based Iron Chelators with Broad-Ranging Biological Activities

Jiang, X., Zhou, T., Bai, R., & Xie, Y. (2020) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.0c01480 · Cited by 54 · see citing works

Modifications of boronic ester pro-chelators triggered by hydrogen peroxide tune reactivity to inhibit metal-promoted oxidative stress

Charkoudian, L. K., Pham, D. M., Kwon, A. M., Vangeloff, A. D., & Franz, K. J. (2007) · Dalton Transactions · doi:10.1039/b705199a · Cited by 53 · see citing works

Inositol hexa phosphoric acid (phytic acid), a nutraceuticals, attenuates iron-induced oxidative stress and alleviates liver injury in iron overloaded mice

Bhowmik, A., Ojha, D., Goswami, D., Das, R., Chandra, N. S., Chatterjee, T. K., Chakravarty, A., Chakravarty, S., & Chattopadhyay, D. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.12.125 · Cited by 53 · see citing works

Polymeric nanocarriers for the treatment of systemic iron overload

Hamilton, J. L., & Kizhakkedathu, J. N. (2015) · Molecular and Cellular Therapies · doi:10.1186/s40591-015-0039-1 · Cited by 50 · see citing works

New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways

Atto, B., Eapen, M. S., Sharma, P. K., Frey, U., Ammit, A. J., Markos, J., Chia, C., Larby, J., Haug, G., Weber, H. C., et al. (2019) · Clinical Science · doi:10.1042/cs20181009 · Cited by 49 · see citing works

Controlling Lipid Oxidation via a Biomimetic Iron Chelating Active Packaging Material

Tian, F., Decker, E. A., & Goddard, J. M. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf4041832 · Cited by 49 · see citing works

Enzymatic synthesis of catechol and hydroxyl-carboxic acid functionalized chitosan microspheres for iron overload therapy

Brzonova, I., Steiner, W., Zankel, A., Nyanhongo, G. S., & Guebitz, G. M. (2011) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2011.04.018 · Cited by 47 · see citing works

New Tris(hydroxypyridinones) as Iron and Aluminium Sequestering Agents: Synthesis, Complexation and In Vivo Studies

Chaves, S., Marques, S. M., Matos, A. M. F., Nunes, A. C. C., Gano, L., Tuccinardi, T., Martinelli, A., & Santos, M. A. (2010) · Chemistry - A European Journal · doi:10.1002/chem.201001335 · Cited by 46 · see citing works

A novel VIVO–pyrimidinone complex: synthesis, solution speciation and human serum protein binding

Gonçalves, G., Tomaz, A. I., Correia, I., Veiros, L. F., Castro, M. M. C. A., Avecilla, F., Palacio, L., Maestro, M. A., Kiss, T., Jakusch, T., et al. (2013) · Dalton Transactions · doi:10.1039/c3dt50553g · Cited by 44 · see citing works

Hydroxypyridinone-benzofuran hybrids with potential protective roles for Alzheimer´s disease therapy

Hiremathad, A., Chand, K., Tolayan, L., Rajeshwari, R., Keri, R. S., Esteves, A. R., Cardoso, S. M., Chaves, S., & Santos, M. A. (2017) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2017.11.015 · Cited by 44 · see citing works

Complexation modulated redox behavior of transition metal systems (review)

Rizvi, M. A. (2015) · Russian Journal of General Chemistry · doi:10.1134/s1070363215040337 · Cited by 43 · see citing works

Fluorescent 3-hydroxy-4-pyridinone hexadentate iron chelators: intracellular distribution and the relevance to antimycobacterial properties

Nunes, A., Podinovskaia, M., Leite, A., Gameiro, P., Zhou, T., Ma, Y., Kong, X., Schaible, U. E., Hider, R. C., & Rangel, M. (2010) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-010-0650-1 · Cited by 41 · see citing works

Reducing power and iron chelating property of Terminalia chebula (Retz.) alleviates iron induced liver toxicity in mice

Sarkar, R., Hazra, B., & Mandal, N. (2012) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-12-144 · Cited by 41 · see citing works

Advancement in the synthesis of metal complexes with special emphasis on Schiff base ligands and their important biological aspects

Singh, P., Yadav, P., Sodhi, K. K., Tomer, A., & Mehta, S. B. (2023) · Results in Chemistry · doi:10.1016/j.rechem.2023.101222 · Cited by 40 · see citing works

Protection from neurodegeneration in the 6-hydroxydopamine (6-OHDA) model of Parkinson's with novel 1-hydroxypyridin-2-one metal chelators

Workman, D. G., Tsatsanis, A., Lewis, F. W., Boyle, J. P., Mousadoust, M., Hettiarachchi, N. T., Hunter, M., Peers, C., Tétard, D., & Duce, J. A. (2015) · Metallomics · doi:10.1039/c4mt00326h · Cited by 40 · see citing works

The Fenton Activity of Iron(III) in the Presence of Deferiprone

Ld, D., Neubert, H., & Hider, R. C. (2007) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.21039 · Cited by 39 · see citing works

Pro-Oxidant Activity of Amine-Pyridine-Based Iron Complexes Efficiently Kills Cancer and Cancer Stem-Like Cells

González‐Bártulos, M., Aceves-Luquero, C., Qualai, J., Cussó, O., Martínez, M. Á., de Mattos, S. F., Menéndez, J. A., Villalonga, P., Costas, M., Ribas, X., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0137800 · Cited by 38 · see citing works

Synthesis and Iron(III)-Chelating Properties of Novel 3-Hydroxypyridin-4-one Hexadentate Ligand-Containing Copolymers

Zhou, T., Kong, X. L., Liu, Z. D., Liu, D. Y., & Hider, R. C. (2008) · Biomacromolecules · doi:10.1021/bm701122u · Cited by 37 · see citing works

Chelated iron sources are inhibitors ofPseudomonas aeruginosabiofilms and distribute efficiently in anin vitromodel of drug delivery to the human lung

Musk, D. J., & Hergenrother, P. J. (2008) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2008.03751.x · Cited by 37 · see citing works

Effect of tris(3-hydroxy-4-pyridinonate) iron(III) complexes on iron uptake and storage in soybean (Glycine max L.)

Santos, C. S., Carvalho, S. M. P., Leite, A., Moniz, T., Roriz, M., Rangel, A. O. S. S., Rangel, M., & Vasconcelos, M. W. (2016) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2016.04.050 · Cited by 37 · see citing works

Enhanced targeting of mitochondrial peroxide defense by the combined use of thiosemicarbazones and inhibitors of thioredoxin reductase

Myers, C. R. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.12.008 · Cited by 36 · see citing works

Iron chelators as therapeutic iron depletion agents

Birch, N. W., Wang, X., & Chong, H. (2006) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543776.16.11.1533 · Cited by 36 · see citing works

Different approaches to the study of chelating agents for iron and aluminium overload pathologies

Crisponi, G., Dean, A., Marco, V. D., Lachowicz, J. I., Nurchi, V. M., Remelli, M., & Tapparo, A. (2012) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-012-6468-7 · Cited by 35 · see citing works

Redox Properties of the Iron Complexes of Orally Active Iron Chelators CP20, CP502, CP509, and ICL670

Merkofer, M., Kissner, R., Hider, R. C., & Koppenol, W. H. (2004) · Helvetica Chimica Acta · doi:10.1002/hlca.200490272 · Cited by 35 · see citing works

Anti-plasmodial activity of aroylhydrazone and thiosemicarbazone iron chelators: Effect on erythrocyte membrane integrity, parasite development and the intracellular labile iron pool

Walcourt, A., Kurantsin‐Mills, J., Kwagyan, J., Adenuga, B., Kalinowski, D. S., Lovejoy, D. B., Lane, D. J. R., & Richardson, D. R. (2013) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2013.08.007 · Cited by 34 · see citing works

Tacrine-(hydroxybenzoyl-pyridone) hybrids as potential multifunctional anti-Alzheimer's agents: AChE inhibition, antioxidant activity and metal chelating capacity

Chand, K., Alsoghier, H. M., Chaves, S., & Santos, M. A. (2016) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2016.05.005 · Cited by 33 · see citing works

Tacrine–deferiprone hybrids as multi-target-directed metal chelators against Alzheimer's disease: a two-in-one drug

Chand, K., Rajeshwari, K., Candeias, E., Cardoso, S. M., Chaves, S., & Santos, M. A. (2018) · Metallomics · doi:10.1039/c8mt00143j · Cited by 33 · see citing works

Beneficial effects of quercetin–iron complexes on serum and tissue lipids and redox status in obese rats

Imessaoudene, A., Merzouk, H., Berroukeche, F., Mokhtari-Soulimane, N. A., Bensenane, B., Cherrak, A., Merzouk, S. A., & Elhabiri, M. (2015) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2015.11.011 · Cited by 33 · see citing works

Biomimetic design of chelating interfaces

Tian, F., Roman, M. J., Decker, E. A., & Goddard, J. M. (2014) · Journal of Applied Polymer Science · doi:10.1002/app.41231 · Cited by 32 · see citing works

Sigma donor and pi acceptor characteristics of certain NN-bidentate ligands: a DFT Study

Maqsood, S. R., Islam, N., Bashir, S., Khan, B., & Pandith, A. H. (2013) · Journal of Coordination Chemistry · doi:10.1080/00958972.2013.800866 · Cited by 32 · see citing works

A DFT study on the complex formation between desferrithiocin and metal ions (Mg2+, Al3+, Ca2+, Mn2+, Fe3+, Co2+, Ni2+, Cu2+, Zn2+)

Kaviani, S., Izadyar, M., & Housaindokht, M. R. (2017) · Computational Biology and Chemistry · doi:10.1016/j.compbiolchem.2016.12.012 · Cited by 32 · see citing works

Design of Iron chelators: Syntheses and iron (III) complexing abilities of tripodal tris-bidentate ligands

d′Hardemare, A. D. M., Torelli, S., Serratrice, G., & Pierre, J. (2006) · BioMetals · doi:10.1007/s10534-005-2997-2 · Cited by 32 · see citing works

The interaction of phenolic acids with Fe(III) in the presence of citrate as studied by isothermal titration calorimetry

Yang, S., Bai, G., Chen, L., Shen, Q., Diao, X., & Zhao, G. (2014) · Food Chemistry · doi:10.1016/j.foodchem.2014.02.052 · Cited by 31 · see citing works

Synthesis and characterization of new β-diketo derivatives with iron chelating ability

Benassi, R., Ferrari, É., Grandi, R., Lazzari, S., & Saladini, M. (2006) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2006.09.020 · Cited by 31 · see citing works

Bis(hydroxyamino)triazines: versatile and high-affinity tridentate hydroxylamine ligands for selective iron( iii ) chelation

Ekeltchik, I., Gun, J., Lev, O. E., Shelkov, R., & Melman, A. (2005) · Dalton Transactions · doi:10.1039/b513719e · Cited by 31 · see citing works

Synthesis and Iron Sequestration Equilibria of Novel Exocyclic 3-Hydroxy-2-pyridinone Donor Group Siderophore Mimics

Harrington, J. M., Chittamuru, S., Dhungana, S., Jacobs, H. K., Gopalan, A. S., & Crumbliss, A. L. (2010) · Inorganic Chemistry · doi:10.1021/ic902595c · Cited by 30 · see citing works

3-Hydroxypyridinone Derivatives as Metal-Sequestering Agents for Therapeutic Use

Santos, M. A., & Chaves, S. (2015) · Future Medicinal Chemistry · doi:10.4155/fmc.14.162 · Cited by 29 · see citing works

Redox activation of Fe(III)–thiosemicarbazones and Fe(III)–bleomycin by thioredoxin reductase: specificity of enzymatic redox centers and analysis of reactive species formation by ESR spin trapping

Myers, J. M., Cheng, Q., Antholine, W. E., Kalyanaraman, B., Filipovska, A., Arnér, E. S. J., & Myers, C. R. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.02.016 · Cited by 30 · see citing works

Ferric Complexes of 3-Hydroxy-4-pyridinones Characterized by Density Functional Theory and Raman and UV–vis Spectroscopies

Šebestı́k, J., Šafařík, M., & Bouř, P. (2012) · Inorganic Chemistry · doi:10.1021/ic202004d · Cited by 30 · see citing works

Unexpected formation of a copper( ii ) 12-metallacrown-4 with (S)-glutamic-γ-hydroxamic acid: a thermodynamic and spectroscopic study in aqueous solution

Tegoni, M., Dallavalle, F., Belosi, B., & Remelli, M. (2004) · Dalton Transactions · doi:10.1039/b316607d · Cited by 29 · see citing works

Design of clinically useful iron(III)‐selective chelators

Liu, Z. D., & Hider, R. C. (2002) · Medicinal Research Reviews · doi:10.1002/med.1027 · Cited by 266 · see citing works

Iron Chelator Chemistry

Liu, Z. D., Liu, D. Y., & Hider, R. C. (2002) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-0593-8_8 · Cited by 15 · see citing works

The Design of Orally Active Iron Chelators

HIDER, R. C., & ZHOU, T. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1345.017 · Cited by 64 · see citing works

Iron Chelator Design

Hider, R. C., Epemolu, O., Singh, S., & Porter, J. B. (1994) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-2554-7_36 · Cited by 19 · see citing works

Coordination Chemistry of Novel Drug Candidates for the Treatment of Iron Overload

Norin, A. (2007) · KTH Publication Database DiVA (KTH Royal Institute of Technology)