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LPS and TNFα induce SOCS3 mRNA and inhibit IL‐6‐induced activation of STAT3 in macrophages
Abstract
Recent findings indicate that cytokine signaling can be modulated by other mediators of simultaneously activated signal transduction pathways. In this study we show that LPS and TNFα are potent inhibitors of IL‐6‐mediated STAT3 activation in human monocyte derived macrophages, rat liver macrophages and RAW 264.7 mouse macrophages but not in human hepatoma cells (HepG2) or in rat hepatocytes. Accordingly, LPS and TNFα were found to induce the expression of SOCS3 mRNA in each of the investigated type of macrophages but not in HepG2 cells. Using a specific inhibitor, evidence is presented that the p38 MAP kinase might be involved, especially for the inhibitory effect of TNFα.
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“Moreover, both hepatocytes in vivo and in culture respond to IL-6 treatment in a similar manner; that is, only STAT-3 homodimers (SIF A) are found (unpublished observations and ref. 30).”
From Expression of suppressors of cytokine signaling during liver regeneration (2001) · cites this paper as [30]
In the citing paper
“One notable exception is the human hepatoma cell line, HepG2 (Figure 1c), where SIF A, B (STAT-3:STAT-1), and C (STAT-1:STAT-1) DNA complexes are all detected after IL-6 treatment (30).”
From Expression of suppressors of cytokine signaling during liver regeneration (2001) · cites this paper as [30]
Citations
Cites
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
Lee, J. C., Laydon, J. T., McDonnell, P., Gallagher, T. F., Kumar, S., Green, D., McNulty, D. E., Blumenthal, M. J., Keys, J., vatter, S. W. L., et al. (1994) · Nature · doi:10.1038/372739a0 · Cited by 3,266
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
Widmann, C., Gibson, S. B., Jarpe, M. B., & Johnson, G. L. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.1.143 · Cited by 2,707
A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells
Han, J., Lee, J. D., Bibbs, L., & Ulevitch, R. J. (1994) · Science · doi:10.1126/science.7914033 · Cited by 2,647
Andrews, N. C., & Faller, D. V. (1991) · Nucleic Acids Research · doi:10.1093/nar/19.9.2499 · Cited by 2,292
Raingeaud, J., Gupta, S., Rogers, J. S., Dickens, M., Han, J., Ulevitch, R. J., & Davis, R. J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.13.7420 · Cited by 2,244
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
HEINRICH, P. C., BEHRMANN, I., MÜLLER-NEWEN, G., SCHAPER, F., & GRAEVE, L. (1998) · Biochemical Journal · doi:10.1042/bj3340297 · Cited by 2,130
Self-citationA family of cytokine-inducible inhibitors of signalling
Starr, R., Willson, T. A., Viney, E. M., Murray, L. J. L., Rayner, J. R., Jenkins, B. J., Gonda, T. J., Alexander, W. S., Metcalf, D., Nicola, N. A., et al. (1997) · Nature · doi:10.1038/43206 · Cited by 2,066
The SIF binding element confers sis/PDGF inducibility onto the c‐fos promoter.
Wagner, B. J., Hayes, T. E., Hoban, C. J., & Cochran, B. H. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07898.x · Cited by 592
Aderka, D., Le, J., & Vilček, J. (1989) · The Journal of Immunology · doi:10.4049/jimmunol.143.11.3517 · Cited by 577
Wegenka, U. M., Buschmann, J., Lütticken, C., Heinrich, P. C., & Horn, F. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.1.276 · Cited by 553
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Pimentel, G. D., Ganeshan, K., & Carvalheira, J. B. C. (2014) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2014.06.005 · Cited by 42
Uchiya, K., & Nikai, T. (2005) · Infection and Immunity · doi:10.1128/iai.73.9.5587-5594.2005 · Cited by 39
Adenoviral-Mediated Overexpression of SOCS3 Enhances IgG Immune Complex-Induced Acute Lung Injury
Gao, H., Hoesel, L. M., Guo, R., Rancilio, N. J., Sarma, J. V., & Ward, P. A. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.1.612 · Cited by 38
Ahmed, S. T., Mayer, A., Ji, J.-D., & Ivashkiv, L. B. (2002) · Journal of Leukocyte Biology · doi:10.1189/jlb.72.1.154 · Cited by 38
Hu, L., Chen, H. H., Zhang, X., Feng, Z., Zhang, H., & Meng, Q. (2020) · Journal of Radiation Research · doi:10.1093/jrr/rraa062 · Cited by 37
Maehr, T., Vecino, J. L. G., Wadsworth, S., Wang, T., & Secombes, C. J. (2014) · Molecular Immunology · doi:10.1016/j.molimm.2014.06.021 · Cited by 36
Zhou, Y. Y., Tao, H., Wang, A., Zhong, Z., Wu, X., Wang, M., Bian, Z., Wang, S., & Wang, Y. (2019) · Chinese Medicine · doi:10.1186/s13020-019-0224-2 · Cited by 36
Deficiency of TNFR1 protects myocardium through SOCS3 and IL-6 but not p38 MAPK or IL-1β
Wang, M., Markel, T. A., Crisostomo, P. R., Herring, C. M., Meldrum, K. K., Lillemoe, K. D., & Meldrum, D. R. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01063.2006 · Cited by 36
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Rex, J., Albrecht, U., Ehlting, C., Thomas, M., Zanger, U. M., Sawodny, O., Häussinger, D., Ederer, M., Feuer, R., & Bode, J. G. (2016) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1005018 · Cited by 33
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Butler, L. M., Jeffery, H. C., Wheat, R. L., Rae, P. C., Townsend, K., Alkharsah, K. R., Schulz, T. F., Nash, G. B., & Blackbourn, D. J. (2011) · Journal of Virology · doi:10.1128/jvi.00021-11 · Cited by 35
Is sprint exercise a leptin signaling mimetic in human skeletal muscle?
Guerra, B., Olmedillas, H., Guadalupe‐Grau, A., Ponce‐González, J. G., Morales‐Álamo, D., Fuentes, T., Chapinal, E., Fernández‐Pérez, L., de Pablos-Velasco, P. L., Santana, A., et al. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00805.2010 · Cited by 34
Graf, D., Kohlmann, C., Haselow, K., Gehrmann, T., Bode, J. G., & Häussinger, D. (2006) · Hepatology · doi:10.1002/hep.21368 · Cited by 32
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Mbow, M. L., & Sarisky, R. T. (2004) · Trends in biotechnology · doi:10.1016/j.tibtech.2004.06.002 · Cited by 33
Heeg, K. M., & Dalpke, A. H. (2003) · Vaccine · doi:10.1016/s0264-410x(03)00202-0 · Cited by 32
Lahti, A., Kankaanranta, H., & Moilanen, E. (2002) · European Journal of Pharmacology · doi:10.1016/s0014-2999(02)02490-1 · Cited by 32
Su, H., Peng, B., Zhang, Z., Liu, Z., & Zhang, Z. (2019) · Molecular Immunology · doi:10.1016/j.molimm.2019.02.021 · Cited by 30
IL-10 receptor dysfunction in macrophages during chronic inflammation
Avdiushko, R., Hongo, D., Lake-Bullock, H., Kaplan, A. M., & Cohen, D. A. (2001) · Journal of Leukocyte Biology · doi:10.1189/jlb.70.4.624 · Cited by 30
The T Cell STAT Signaling Network Is Reprogrammed within Hours of Bacteremia via Secondary Signals
Hotson, A. N., Hardy, J. W., Hale, M. B., Contag, C. H., & Nolan, G. P. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803666 · Cited by 28
Gupta, G. K., Dhar, K., Core, M. G. D., Hunter, W. J., Hatzoudis, G. I., & Agrawal, D. K. (2011) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2011.04.004 · Cited by 28
Synergistic and antagonistic interactions between LPS and superantigens
Dalpke, A. H., & Heeg, K. M. (2003) · Journal of Endotoxin Research · doi:10.1177/09680519030090010601 · Cited by 28
Miyaaki, H., Ichikawa, T., Nakao, K., Matsuzaki, T., Muraoka, T., Honda, T., Takeshita, S., Shibata, H., Ozawa, E., Akiyama, M., et al. (2009) · Hepatology Research · doi:10.1111/j.1872-034x.2009.00529.x · Cited by 26
Oncostatin M regulates SOCS3 mRNA stability via the MEK–ERK1/2-pathway independent of p38MAPK/MK2
Ehlting, C., Böhmer, O., Hahnel, M. J., Thomas, M., Zanger, U. M., Gaestel, M., Knoefel, W. T., Esch, J. S. A., Häussinger, D., & Bode, J. G. (2015) · Cellular Signalling · doi:10.1016/j.cellsig.2014.12.016 · Cited by 25
Self-citationYang, X., Albrecht, U., Zakowski, V., Sobota, R. M., Häussinger, D., Heinrich, P. C., Ludwig, S., Bode, J. G., & Schaper, F. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313072200 · Cited by 26
Self-citationBroeren, M. G. A., de Vries, M., Bennink, M. B., Arntz, O. J., van Lent, P. L. E. M., van der Kraan, P. M., van den Berg, W. B., van den Hoogen, F. H. J., Koenders, M. I., & van de Loo, F. A. J. (2016) · Arthritis Research & Therapy · doi:10.1186/s13075-016-1083-1 · Cited by 24
Uchiya, K., & Nikai, T. (2008) · Microbiology · doi:10.1099/mic.0.2008/021667-0 · Cited by 24
Unravelling the druggability and immunological roles of the SOCS-family proteins
Lynch, D. M., Forrester, B., Webb, T., & Ciulli, A. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1449397 · Cited by 25
Siavash, H., Nikitakis, N. G., & Sauk, J. J. (2004) · British Journal of Cancer · doi:10.1038/sj.bjc.6602055 · Cited by 22
Isobe, A., Takeda, T., Sakata, M., Yamamoto, T., Minekawa, R., Hayashi, M., Auernhammer, C. J., Tasaka, K., & Murata, Y. (2005) · Placenta · doi:10.1016/j.placenta.2005.10.003 · Cited by 23
Host microbiota dictates the proinflammatory impact of LPS in the murine liver
Suriguga, S., Luangmonkong, T., Mutsaers, H. A. M., Groothuis, G. M. M., & Olinga, P. (2020) · Toxicology in Vitro · doi:10.1016/j.tiv.2020.104920 · Cited by 22
Expression of STAT3 and SOCS3 in Pancreatic Acinar Cells1,2
Vona-Davis, L. C., Frankenberry, K. A., Waheed, U., Peterson, E. J., & McFadden, D. W. (2005) · Journal of Surgical Research · doi:10.1016/j.jss.2005.03.019 · Cited by 22
SOCS3 dictates the transition of divergent time-phased events in granulocyte TNF-α signaling
Chhabra, J. K., Chattopadhyay, B., & Paul, B. N. (2013) · Cellular and Molecular Immunology · doi:10.1038/cmi.2013.36 · Cited by 21
Jang, H.-S., Chung, H., Ko, E., Shin, J., Shin, M., Hong, M., Kim, Y., Min, B.-I., & Bae, H. (2008) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2008.09.006 · Cited by 21
Boswell, M., Boswell, W. T., Lü, Y., Savage, M. G., Mazurek, Z., Chang, J. T., Muster, J., & Walter, R. B. (2017) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2017.10.003 · Cited by 20
Swiderski, K., Thakur, S. S., Naim, T., Trieu, J., Chee, A., Stapleton, D., Koopman, R., & Lynch, G. S. (2016) · Skeletal Muscle · doi:10.1186/s13395-016-0108-4 · Cited by 21
Foka, P. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg861 · Cited by 20
Dagvadorj, J., Naiki, Y., Tumurkhuu, G., Noman, A. S. M., Iftakhar-E-Khuda, I., Komatsu, T., Koide, N., Yoshida, T., & Yokochi, T. (2009) · Immunology · doi:10.1111/j.1365-2567.2009.03154.x · Cited by 18
Chakraborty, R., Vickery, K., Darido, C., Ranganathan, S., & Hu, H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168686 · Cited by 17
Oberbach, A., Schlichting, N. S., Heinrich, M., Till, H., Stolzenburg, J., & Neuhaus, J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041026 · Cited by 16
Pagliara, V., Parafati, M., Adornetto, A., White, M. C., Masullo, M., GRIMALDI, M., & Arcone, R. (2018) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2018.06.016 · Cited by 15
Reuben, J. S., Dinh, L., Lee, J., Stateson, J., Kamara, H., Xiang, L., & Opperman, L. A. (2011) · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology · doi:10.1016/j.tripleo.2010.09.068 · Cited by 16
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Terstegen, L., Gatsios, P., Ludwig, S., Pleschka, S., Jahnen‐Dechent, W., Heinrich, P. C., & Graeve, L. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.9.5209 · Cited by 15
Self-citationCaspase-mediated cleavage of the signal-transducing IL-6 receptor subunit gp130
Graf, D., Haselow, K., Münks, I., Bode, J. G., & Häussinger, D. (2008) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2008.06.009 · Cited by 14
Self-citationSubathra, M., Nandi, B. R., Mazumdar, V. B., Joshi, K., Nandini, P., Namani, S., Jakka, P., & Radhakrishnan, G. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.105309 · Cited by 14
Yan, C., Liu, Y., Gao, H., & Wang, X. (2015) · Experimental Cell Research · doi:10.1016/j.yexcr.2015.07.017 · Cited by 14
Mechanism of crosstalk inhibition of IL-6 signaling in response to LPS and TNFα
Kiu, H., Hilton, D. J., Nicola, N. A., Ernst, M., Márquez, R., Alexander, W. S., Roberts, A. W., & McManus, E. J. (2007) · Growth Factors · doi:10.1080/08977190701830151 · Cited by 14
Han, S. K., Jeon, S. J., Miyazawa, K., Yi, S. Y., & Yoo, Y. S. (2006) · Rheumatology International · doi:10.1007/s00296-006-0109-4 · Cited by 14
Siavash, H., Nikitakis, N. G., & Sauk, J. J. (2004) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/154411130401500505 · Cited by 14
Suppressors of cytokine signaling proteins in innate and adaptive immune responses.
Dalpke, A. H., & Heeg, K. M. (2003) · PubMed · Cited by 14
Komine, O., Ohnuma, S., Hinohara, K., Hara, Y., Shimada, M., Akashi, T., Watanabe, S., Sobue, A., Kawade, N., Ogi, T., et al. (2024) · iScience · doi:10.1016/j.isci.2024.108872 · Cited by 12
Ehlting, C., Rex, J., Albrecht, U., Deenen, R., Tiedje, C., Köhrer, K., Sawodny, O., Gaestel, M., Häussinger, D., & Bode, J. G. (2019) · Scientific Reports · doi:10.1038/s41598-019-46791-8 · Cited by 13
Self-citationHonke, N., Ohl, K., Wiener, A., Bierwagen, J., Peitz, J., Fiore, S. D., Fischer, R., Wagner, N., Wüller, S., & Tenbrock, K. (2013) · Arthritis & Rheumatology · doi:10.1002/art.38245 · Cited by 13
Takakura, R., Kiyohara, T., Murayama, Y., Miyazaki, Y., Miyoshi, Y., Shinomura, Y., & Matsuzawa, Y. (2002) · Inflammation Research · doi:10.1007/pl00000322 · Cited by 13
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Kong, F., Guo, X., Noel, J. G., Wells, D. A., Lovell, G. J., & Ogle, C. K. (2002) · Shock · doi:10.1097/00024382-200210000-00014 · Cited by 13
Nasreen, N., Khodayari, N., Sukka-Ganesh, B., Sriram, P., & Mohammed, K. A. (2011) · International Immunopharmacology · doi:10.1016/j.intimp.2011.11.014 · Cited by 12
Kakhki, M. P., Rakhshi, N., Aleagha, M. S. E., Abdari, M., Alikhah, A., Safarian, G., Behmanesh, M., & Nikravesh, A. (2019) · Neurological Sciences · doi:10.1007/s10072-019-04092-y · Cited by 12
Nasreen, N., Gonzalves, L., Sriram, P., & Mohammed, K. A. (2014) · International Immunopharmacology · doi:10.1016/j.intimp.2013.12.029 · Cited by 12
Demirel, I., Säve, S., Kruse, R. L., & Persson, K. (2012) · Apmis · doi:10.1111/j.1600-0463.2012.02951.x · Cited by 12
He, J., Tang, M., Liu, L.-X., Kong, C.-X., Chen, W., Wang, L., Zhi, S.-B., Sun, H., Huang, Y.-C., Chen, G.-Y., et al. (2024) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2024.01.023 · Cited by 11
Lutz, H. H., Sackett, S. D., Kroy, D. C., Gaßler, N., & Trautwein, C. (2011) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2011.09.006 · Cited by 11
Drew, J. E., Farquharson, A. J., Horgan, G. W., Duthie, S. J., & Duthie, G. G. (2014) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201400331 · Cited by 11
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Bodmer, D. (2017) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2017.1372744 · Cited by 10
Huo, R., Chu, Q., Zhao, X., Liu, X., & Xu, T. (2020) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2020.103723 · Cited by 10
Shin, J.-J., Suk, K., & Lee, W. (2024) · Scientific Reports · doi:10.1038/s41598-024-77265-1 · Cited by 9
Ghosh, R. B., & Bishayi, B. (2023) · Microbial Pathogenesis · doi:10.1016/j.micpath.2023.106518 · Cited by 8
Jiang, X. X., He, M., Bai, J., Chan, C. B., & Wong, A. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00020 · Cited by 8
Proinflammatory Stem Cell Signaling in Cardiac Ischemia
Herrmann, J. L., Markel, T. A., Abarbanell, A. M., Weil, B. R., Wang, M., Wang, Y., Tan, J., & Meldrum, D. R. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2434 · Cited by 8
Ling, P., Smith, R. J., Mueller, C., Mao, Y., & Bistrian, B. R. (2002) · Critical Care Medicine · doi:10.1097/00003246-200201000-00029 · Cited by 8
Pretreatment of LPS inhibits IFN-β-induced STAT1 phosphorylation through SOCS3 induced by LPS
Ando, T., Komatsu, T., Naiki, Y., Yokochi, T., Watanabe, D., & Koide, N. (2015) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2015.10.019 · Cited by 7
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Tsai, W.-C., Bai, L., Chen, Y.-J., Chu, P., Hsu, Y.-W., Sargeant, A. M., & Weng, J. (2017) · Oncotarget · doi:10.18632/oncotarget.16450 · Cited by 7
Muramatsu, H., Welsh, F. A., & Karikó, K. (2006) · Brain Research · doi:10.1016/j.brainres.2006.04.067 · Cited by 6
Wakayama, S., Haque, A., Koide, N., Kato, Y., Odkhuu, E., Tsolmongyn, B., Naiki, Y., Komatsu, T., Yoshida, T., & Yokochi, T. (2014) · Immunopharmacology and Immunotoxicology · doi:10.3109/08923973.2014.887096 · Cited by 6
Sobah, M. L., Liongue, C., & Ward, A. C. (2024) · Journal of Innate Immunity · doi:10.1159/000538364 · Cited by 4
Gao, Q., Huan, C., Jia, Z., Cao, Q., Yuan, P., Li, X., Wang, C., Mao, Z., & Huo, W. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252212113 · Cited by 4
Allogeneic activation is attenuated in a model of mouse lung perfused with magnesium-deficient blood
Sabbagh, F., Lecerf, F., Maurois, P., Bac, P., & German-Fattal, M. (2006) · Transplant Immunology · doi:10.1016/j.trim.2006.09.002 · Cited by 3
Du, K., Chai, Y., Hou, L., Chang, W., Chen, S., Luo, W., Cai, T., Zhang, X., Chen, N., Chen, Y., et al. (2007) · Toxicology · doi:10.1016/j.tox.2007.10.025 · Cited by 2
Xing, C., Zhang, D.-X., Gui, S.-Q., & Tao, M. (2017) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2017/2473431 · Cited by 2
Altman, A. (2015) · UKnowledge (University of Kentucky) · Cited by 2
STAT/SOCS Family Members in Inflammation and Diseases
Yoshimura, A., Kinjyo, I., Inagaki‐Ohara, K., & Hanada, T. (2003) · Springer eBooks · doi:10.1007/978-94-017-3000-6_34 · Cited by 1
Kuravi, S. J. (2012) · OpenGrey (Institut de l'Information Scientifique et Technique)
Woodward, E. (2011) · Murdoch University Research Portal
INTERLEUKIN-10 RECEPTOR DYSFUNCTION IN PERITONEAL MACROPHAGES BY TOLL-LIKE RECEPTOR LIGANDS
Bhattacharyya, S. (2005) · UKnowledge (University of Kentucky)
SOCS and inflammation in chronic renal failure
Rastmanesh, M. M. (2008) · Utrecht University Repository (Utrecht University)
Negative Regulator of Cytokine Signaling (SOCS) Genes in Inflammation
Yasukawa, H., Kinjyo, I., & Yoshimura, A. (2003) · Developments in cardiovascular medicine · doi:10.1007/978-1-4419-9264-2_3
Role of SOCS proteins in T helper cell differentiation and allergic inflammatory responses
Kubo, M. (2005) · Inflammation and Regeneration · doi:10.2492/jsir.25.436
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Li, Y. (2012) · EUR Research Repository (Erasmus University Rotterdam)
The regulation of gp130 surface expression on monocytes : implications in chronic inflammation
Honke, N., Idm, P., Fischer, R., & Tenbrock, K. (2014) · RWTH Publications (RWTH Aachen)
Microglial regulation by astrocytes
Acevedo, G. (2013) · Rutgers University Community Repository (Rutgers University) · doi:10.7282/t3ks6q8v
Mathematisch-naturwissenschaftlichen Fakultät, I. (2009)
Modulation of Cytokine Signaling by B. burgdorferi
Dennis, V. A., Gautam, A., & Dixit, S. (2012) · Springer eBooks · doi:10.1007/978-1-4614-5404-5_7
Self-tolerance in collagen induced arthritis
Eneljung, T. (2013) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Étude du rôle du transporteur de phosphate inorganique PiT1/SLC20A1 dans l'inflammation
Koumakis, E. (2016) · theses.fr (ABES) · doi:10.70675/7bdb44faz8800z4b6dz9e92zce56d29c4f27
Clère-Jehl, R. (2020) · theses.fr (ABES) · doi:10.70675/a65a57a6ze1d1z47baz8fa5zabef17722df4
The Senescent Cell Induced Bystander Effect
Wordsworth, J. (2014)
Yang, X., & Heinrich, P. C. (2005) · RWTH Publications (RWTH Aachen)
Self-citation
Metadata
- Authors
- Bode, J. G., Nimmesgern, A., Schmitz, J., Schaper, F., Schmitt, M., Frisch, W., Häussinger, D., Heinrich, P. C., & Graeve, L.
- Affiliations
- Universitätsklinikum Aachen (DE)
- RWTH Aachen University (DE)
- Düsseldorf University Hospital (DE)
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1999-12-17
- Volume
- 463
- Issue
- 3
- Pages
- 365-370
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2000974116
- Semantic Scholar
- 7c9e34a7b209b7772b86c66230245c02502400ce
- Cited by
- 196
- References
- 31
- Citations by year
- 2024: 6 · 2023: 2 · 2021: 3 · 2020: 8 · 2019: 5 · 2018: 2 · 2017: 7 · 2016: 6 · 2015: 5 · 2014: 10 · 2013: 6 · 2012: 13
- FWCI
- 3.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- FEBS Letters (publishedVersion)
- PubMed (publishedVersion)
- RWTH Publications (RWTH Aachen) (submittedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Cytokine Signaling Pathways and Interactions
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Tyrosine Phosphatases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › NF-κB Signaling Pathways
- Keywords
- SOCS3, STAT3 activation, IL-6 signaling, lipopolysaccharide, TNF-α, macrophages, p38 MAPK, hepatic macrophages, hepatocytes
- MeSH terms
- Interleukin-6 Inhibitors, Animals, Cell Line, DNA-Binding Proteins, Gene Expression Regulation, Humans, Kupffer Cells, Lipopolysaccharides, Liver, Macrophages, Male, Tumor Cells, Cultured, Tumor Necrosis Factor-alpha, Signal Transduction, Trans-Activators, Genes, Suppressor, Rats, Wistar, Mitogen-Activated Protein Kinases, p38 Mitogen-Activated Protein Kinases, STAT3 Transcription Factor, Mice, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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