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Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neurons

Bu, G., Maksymovitch, E.A., Nerbonne, J.M., Schwartz, A.L.·1994·Journal of Biological Chemistry
DOI 10.1016/s0021-9258(17)32340-2
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  • Activated astrocytes used in the experiments express both LDLR and LRP by immunostaining.

    “By immunostaining, these activated astrocytes express both the LDLR and LRP (data not shown), consistent with the previous observations summarized above that these are the two primary members of the LDLR family that are expressed by activated astrocytes (4 -7, 29 -31).”

    From Apolipoprotein E Receptors Mediate the Effects of β-Amyloid on Astrocyte Cultures (2000) · cites this paper as [29]

    In the discussion of LRP expression (page unavailable), the paper reports detectable LRP mRNA in astrocytes. It does not show that activated astrocytes express both LRP and LDLR by immunostaining; its mention of LDLR concerns localization elsewhere in the central nervous system. (LLM, conf=0.86)

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Metadata

Authors
Bu, G., Maksymovitch, E. A., Nerbonne, J. M., & Schwartz, A. L.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
1994-07
Volume
269
Issue
28
Pages
18521-18528
ISSN
0021-9258
DOI
10.1016/s0021-9258(17)32340-2
Cited by
185
References
0
Language
en
Licence

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