The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Mitochondrial uncoupling protein from mouse brown fat. Molecular cloning, genetic mapping, and mRNA expression
Open accessAbstract
We have identified cDNAs clones for several cold-inducible mRNAs from the brown adipose tissue of mice. pCIN-1, a plasmid with a 900-base pair insert, encoded the mitochondrial uncoupling protein (UCP) as determined by the ability of the cDNA insert to select, by hybridization, an mRNA that could be translated into a 32,000-Da protein immunoprecipitable with anti-UCP antibodies. Nine tissues were analyzed; however, UCP cDNA hybridized to an mRNA species of 1.6 and 2.0 kilobase pairs only in brown adipose tissue. A maximum induction of 10-fold occurred within 6 h of exposure to cold (5 degrees C). A BamHI restriction fragment polymorphism detected by Southern blot analysis of genomic DNA in recombinant inbred mouse strains allowed us to map the UCP gene to Chromosome 8. The analysis of the UCP gene expression in diabetic (db) and obese (ob) mice maintained at 27 degrees C for 3 days followed by cold exposure for 4 h at 5 degrees C indicated that UCP mRNA levels in mutant mice were unaffected at 27 degrees C and only slightly reduced at 5 degrees C. Accordingly, the inability of diabetic and obese mice to thermoregulate is not associated with a lack of UCP mRNA induction.
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“Importantly, although strong evidence of the mitochondrial uncoupling property is clear for UCP-1 [7,12], it is still heavily debated for the other UCPs [13,14,15].”
From Mitochondrial Uncoupling: A Key Controller of Biological Processes in Physiology and Diseases (2019) · cites this paper as [7]
Experimental — accuracy not yet measuredIn the citing paper
“UCP-1 is a transmembrane protein localized in the inner mitochondrial membrane catalyzing the transport of protons across the mitochondrial membrane and thereby inducing mitochondrial uncoupling [7].”
From Mitochondrial Uncoupling: A Key Controller of Biological Processes in Physiology and Diseases (2019) · cites this paper as [7]
In the citing paper
“In this tissue, electron transport is greatly accelerated due to tissue-specific expression of the mitochondrial UCP1.”
From The role of mitochondria in the pathogenesis of type 2 diabetes (2010) · cites this paper as [154]
In the citing paper
“UCP1 hinders the establishment of, or dissipates, a proton gradient of sufficient magnitude to sustain the synthetic activity of the mitochondrial ATPase (150, 153-155), thus driving continuous accelerated electron transport.”
From The role of mitochondria in the pathogenesis of type 2 diabetes (2010) · cites this paper as [154]
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Citations
Cites
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961
Rigby, P. W. J., Dieckmann, M., Rhodes, C., & Berg, P. R. (1977) · Journal of Molecular Biology · doi:10.1016/0022-2836(77)90052-3 · Cited by 11,400
Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography
Laskey, R. A., & Mills, A. D. (1975) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1975.tb02238.x · Cited by 4,629
Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.
Grunstein, M. R., & Hogness, D. S. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.10.3961 · Cited by 3,386
Thermogenic mechanisms in brown fat.
Nicholls, D. G., & Locke, R. M. (1984) · Physiological Reviews · doi:10.1152/physrev.1984.64.1.1 · Cited by 1,602
Genetic variants and strains of the laboratory mouse
(1990) · Choice Reviews Online · doi:10.5860/choice.28-1324 · Cited by 1,492
NON‐SHIVERING THERMOGENESIS AND ITS THERMOREGULATORY SIGNIFICANCE
Janský, L. (1973) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/j.1469-185x.1973.tb01115.x · Cited by 612
Transcriptional control in the production of liver-specific mRNAs
Derman, E., Krauter, K. S., Walling, L. L., Weinberger, C., Ray, M., & Darnell, J. E., Jr. (1981) · Cell · doi:10.1016/0092-8674(81)90436-0 · Cited by 550
Foster, D. O., & Frydman, M. L. (1979) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y79-039 · Cited by 518
Maccecchini, M. L., Rudin, Y., Blobel, G., & Schatz, G. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.1.343 · Cited by 453
Research works printed but not linked: 6
- Krawetz, 1984, Biotechniques, 2, 342
- Moutier, 1978, Mouse Newsletter, 58, 64
- Sundin, 1980, Comp. Biochem. Biophys., 65B, 463
- Nedergaard, 1985, Am. J. Physiol.
- Hogan, 1980, Am. J. Physiol., 239, E301
- Zaror-Behrens, 1983, Am. J. Physiol., 244, E361
Cited by
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Hansen, K. R., Krasnow, S. M., Nolan, M. A., Fraley, G. S., Baumgartner, J. W., Clifton, D. K., & Steiner, R. A. (2003) · Endocrinology · doi:10.1210/en.2003-0748 · Cited by 68
Rabelo, R., Reyes, C., Schifman, A. L., & Silva, J. E. (1996) · Endocrinology · doi:10.1210/endo.137.8.8754777 · Cited by 68
α- and β-adrenergic control of thermogenin mRNA expression in brown adipose tissue
Jacobsson, A., Nedergaard, J., & Cannon, B. (1986) · Bioscience Reports · doi:10.1007/bf01114756 · Cited by 68
Self-citationEndo, T., & Kobayashi, T. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90433.2008 · Cited by 67
Lee, M.-S., Shin, Y., Jung, S., & Kim, Y. (2017) · Food & Nutrition Research · doi:10.1080/16546628.2017.1325307 · Cited by 66
Sex‐Dependent Dietary Obesity, Induction of UCPs, and Leptin Expression in Rat Adipose Tissues
Rodríguez, A. M., Quevedo, S., Roca, P., & Palou, A. (2001) · Obesity Research · doi:10.1038/oby.2001.75 · Cited by 66
Reifel-Miller, A. E., Otto, K. A., Hawkins, E. D., Barr, R. J., Bensch, W. R., Bull, C., Dana, S. L., Klausing, K., Martin, J.-A., Rafaeloff-Phail, R., et al. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0015 · Cited by 65
Regulation of Feeding-Associated Peptides and Receptors by Nicotine
Li, M. D., Parker, S. L., & Kane, J. K. (2000) · Molecular Neurobiology · doi:10.1385/mn:22:1-3:143 · Cited by 65
QTL analysis of self-selected macronutrient diet intake: fat, carbohydrate, and total kilocalories
Richards, B. K. S., Belton, B. N., Poole, A. C., Mancuso, J. J., Churchill, G. A., Li, R., Vólaufová, J., Zuberi, A. R., & York, B. (2002) · Physiological Genomics · doi:10.1152/physiolgenomics.00037.2002 · Cited by 65
Sexual dimorphism in the adrenergic control of rat brown adipose tissue response to overfeeding
Rodríguez, E., Monjo, M., Rodríguez‐Cuenca, S., Pujol, E., Amengual, B., Roca, P., & Palou, A. (2001) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s004240100556 · Cited by 64
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Lee, P. L., Jung, S. M., & Guertin, D. A. (2017) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2017.01.004 · Cited by 66
Muzzin, P. (2002) · PubMed · Cited by 63
Cell Fate and Differentiation of Bone Marrow Mesenchymal Stem Cells
Kokabu, S., Lowery, J. W., & Jimi, E. (2016) · Stem Cells International · doi:10.1155/2016/3753581 · Cited by 65
Effects of Obesity and Stable Weight Reduction on UCP2 and UCP3 Gene Expression in Humans
Vidal‐Puig, A., ROSENBAUM, M. S., Considine, R. V., Leibel, R. L., Dohm, G. L., & Lowell, B. B. (1999) · Obesity Research · doi:10.1002/j.1550-8528.1999.tb00694.x · Cited by 62
Klaus, S., Cassard, A., & Ricquier, D. (1991) · The Journal of Cell Biology · doi:10.1083/jcb.115.6.1783 · Cited by 61
Transcriptional Activation of the Human ucp1 Gene in a Rodent Cell Line
González‐Barroso, M. M., Pecqueur, C., Gelly, C., Sanchís, D., Alves‐Guerra, M., Bouillaud, F., Ricquier, D., & Cassard, A. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001678200 · Cited by 57
Law, J., Chalmers, J., Morris, D. E., Robinson, L., Budge, H., & Symonds, M. E. (2017) · Temperature · doi:10.1080/23328940.2017.1397085 · Cited by 65
Guardiola‐Diaz, H. M., Rehnmark, S., Usuda, N., Albrektsen, T., Feltkamp, D., Gustafsson, J.-Α., & Alexson, S. E. H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.33.23368 · Cited by 59
Boyer, B. B., & Kozak, L. P. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.8.4147 · Cited by 58
Self-citationThyroid hormones in the regulation of brown adipose tissue thermogenesis
Sentis, S. C., Oelkrug, R., & Mittag, J. (2021) · Endocrine Connections · doi:10.1530/ec-20-0562 · Cited by 60
Bouillaud, F., Raimbault, S., & Ricquier, D. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(88)80318-8 · Cited by 57
Ovnic, M., Swank, R. T., Fletcher, C., Zhen, L., Novak, E. K., Baumann, H., Heintz, N., & Ganschow, R. E. (1991) · Genomics · doi:10.1016/0888-7543(91)90020-f · Cited by 57
Dridi, S., Onagbesan, O. M., Swennen, Q., Buyse, J. G., Decuypere, E. M. P., & Taouis, M. (2004) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpb.2004.09.010 · Cited by 56
Aoki, K., Sun, Y., Aoki, S., Wada, K., & Wada, E. (2002) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2002.6337 · Cited by 55
Regulation of expression of the lipoprotein lipase gene in brown adipose tissue
Mitchell, J. R., Jacobsson, A., Kirchgessner, T. G., Schotz, M. C., Cannon, B., & Nedergaard, J. (1992) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1992.263.3.e500 · Cited by 55
Self-citationPazos-Moura, C. C., de Moura, E. G., Dorris, M. L., Rehnmark, S., Melendez, L., Silva, J. E., & Taurog, A. (1991) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1991.260.2.e175 · Cited by 55
Obesity research springs a proton leak
Flier, J. S., & Lowell, B. B. (1997) · Nature Genetics · doi:10.1038/ng0397-223 · Cited by 53
The mitochondrial uncoupling protein: structural and genetic studies.
Ricquier, D., & Bouillaud, F. (1997) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(08)61003-x · Cited by 52
Brown Fat UCP1 Is Specifically Expressed in Uterine Longitudinal Smooth Muscle Cells
Nibbelink, M. M., Moulin, K., Arnaud, E., Duval, C., Pénicaud, L., & Casteilla, L. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105658200 · Cited by 52
Induction of Uncoupling Protein Expression in Brown and White Adipose Tissue by Leptin
Commins, S. P. (1999) · Endocrinology · doi:10.1210/en.140.1.292 · Cited by 50
Brown, D., Lafuse, W. P., & Zwilling, B. S. (1995) · Infection and Immunity · doi:10.1128/iai.63.8.2983-2988.1995 · Cited by 49
Leptin Potentiates Thermogenic Sympathetic Responses to Hypothermia
Hausberg, M., Morgan, D. A., Mitchell, J., Sivitz, W. I., Mark, A. L., & Haynes, W. G. (2002) · Diabetes · doi:10.2337/diabetes.51.8.2434 · Cited by 48
Is thermogenesis a significant causal factor in preventing the “globesity” epidemic?
Hansen, J. C., Gilman, A. P., & Odland, J. Ø. (2010) · Medical Hypotheses · doi:10.1016/j.mehy.2010.02.033 · Cited by 51
ELOVL2 overexpression enhances triacylglycerol synthesis in 3T3‐L1 and F442A cells
Kobayashi, T., Zadravec, D., & Jacobsson, A. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.05.081 · Cited by 48
Self-citationObregón, M.-J., Jacobsson, A., Kirchgessner, T. G., Schotz, M. C., Cannon, B., & Nedergaard, J. (1989) · Biochemical Journal · doi:10.1042/bj2590341 · Cited by 47
Self-citationThe Effects of the β3-Adrenoceptor Agonist BRL 35135 on UCP Isoform mRNA Expression
Emilsson, V., Summers, R. J., Hamilton, S., Liu, Y.-L., & Cawthorne, M. A. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9667 · Cited by 47
Leiter, E. H., Fewell, J. W., & Kuff, E. L. (1986) · The Journal of Experimental Medicine · doi:10.1084/jem.163.1.87 · Cited by 47
Obregón, M.-J., Pitamber, R., Jacobsson, A., Nedergaard, J., & Cannon, B. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(87)91069-2 · Cited by 46
Self-citationElovl3: a model gene to dissect homeostatic links between the circadian clock and nutritional status
Anzulovich, A. C., Mir, A. A., Brewer, M., Ferreyra, G. A., Vinson, C., & Baler, R. (2006) · Journal of Lipid Research · doi:10.1194/jlr.m600230-jlr200 · Cited by 49
MNADK, a novel liver-enriched mitochondrion-localized NAD kinase
Zhang, R. (2013) · Biology Open · doi:10.1242/bio.20134259 · Cited by 45
Physiological activation of brown adipose tissue destabilizes thermogenin mRNA
Jacobsson, A., Cannon, B., & Nedergaard, J. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)80483-0 · Cited by 44
Self-citationSchäffler, Palitzsch, Watzlawek, Drobnik, Schwer, Schölmerich, & Schmitz (1999) · European Journal of Clinical Investigation · doi:10.1046/j.1365-2362.1999.00529.x · Cited by 44
Kageyama, H., Suga, A., Kashiba, M., Oka, J., Osaka, T., Kashiwa, T., Hirano, T., Nemoto, K., Namba, Y., Ricquier, D., et al. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)01506-3 · Cited by 43
Hidaka, S., Kakuma, T., Yoshimatsu, H., Yasunaga, S., Kurokawa, M., & Sakata, T. (1998) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/s0005-2760(97)00188-4 · Cited by 43
Differential adrenergic regulation of C/EBPα and C/EBPβ in brown adipose tissue
Rehnmark, S., Antonson, P., Xanthopoulos, K. G., & Jacobsson, A. (1993) · FEBS Letters · doi:10.1016/0014-5793(93)80519-z · Cited by 41
Self-citationWIdespread increases in regional hypothalamic neuropeptide Y levels in acute cold-exposed rats
McCarthy, H. D., Kilpatrick, A. P., Trayhurn, P., & Williams, G. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90388-v · Cited by 41
Melatonin multiple effects on brown adipose tissue molecular machinery
de Souza, C. A. P., Gallo, C. C., de Camargo, L. S., de Carvalho, P. V. V., Olesçuck, I. F., Macedo, F. P., da Cunha, F. M., Cipolla‐Neto, J., & do Amaral, F. G. (2018) · Journal of Pineal Research · doi:10.1111/jpi.12549 · Cited by 41
Rim, J. S., Xue, B., Gawrońska‐Kozak, B., & Kozak, L. P. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402102200 · Cited by 41
Self-citationThe congenital goiter mutation is linked to the thyroglobulin gene in the mouse.
Taylor, B. A., & Rowe, L. B. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.7.1986 · Cited by 41
Ceci, J. D. (1991) · Mammalian Genome · doi:10.1007/bf00656489 · Cited by 41
Mitochondrial efficiency: lessons learned from transgenic mice
Harper, M., & Himms‐Hagen, J. (2001) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(00)00244-9 · Cited by 39
Murholm, M., Dixen, K., Qvortrup, K., Hansen, L. H. L., Amri, E., Madsen, L., Barbatelli, G., Quistorff, B., & Hansen, J. B. (2009) · PLoS ONE · doi:10.1371/journal.pone.0008458 · Cited by 41
A glycerol-3-phosphate dehydrogenase null mutant in BALB/cHeA mice
Procházka, M., Kozak, U. C., & Kozak, L. P. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)83796-6 · Cited by 39
Self-citationPicó, C., Herron, D. K., Palou, A., Jacobsson, A., Cannon, B., & Nedergaard, J. (1994) · Biochemical Journal · doi:10.1042/bj3020081 · Cited by 39
Self-citationReiter, R. J., Klaus, S., EBBINGHAUS, C., Heldmaier, G., Redlin, U., Ricquier, D., Vaughan, M. K., & Steinlechner, S. (1990) · Endocrinology · doi:10.1210/endo-126-5-2550 · Cited by 39
An interspecific backcross linkage map of mouse chromosome 8
Ceci, J. D., Justice, M. J., Lock, L. F., Jenkins, N. A., & Copeland, N. G. (1990) · Genomics · doi:10.1016/0888-7543(90)90449-5 · Cited by 39
Bini, S., D’Erasmo, L., Costanzo, A. D., Minicocci, I., Pecce, V., & Arca, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22020742 · Cited by 38
IL-1 and LPS but not IL-6 inhibit differentiation and downregulate PPAR gamma in brown adipocytes
Mráček, T., Cannon, B., & Houštěk, J. (2004) · Cytokine · doi:10.1016/j.cyto.2003.12.001 · Cited by 38
Nolan, M. A., Sikorski, M. A., & McKnight, G. S. (2004) · Molecular Endocrinology · doi:10.1210/me.2004-0194 · Cited by 38
MATAMALA, J. C., Gianotti, M., Pericás, J., QUEVEDO, S., Roca, P., Palou, A., & García-Palmer, F. (1996) · Biochemical Journal · doi:10.1042/bj3190529 · Cited by 38
Thymus Uncoupling Protein 1 Is Exclusive to Typical Brown Adipocytes and Is Not Found in Thymocytes
Frontini, A., Rousset, S., Cassard, A., Zingaretti, C. M., Ricquier, D., & Cinti, S. (2006) · Journal of Histochemistry & Cytochemistry · doi:10.1369/jhc.6a7013.2006 · Cited by 36
DHEA administration increases brown fat uncoupling protein 1 levels in obese OLETF rats
Ryu, J., Kim, M., Kim, C., Song, K., Park, J., Lee, J.-D., Kim, J. B., & Lee, K. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00409-1 · Cited by 37
Jonghe, B. C. D., Hayes, M. R., Banno, R., Skibicka, K. P., Zimmer, D. J., Bowen, K. A., Leichner, T. M., Alhadeff, A. L., Kanoski, S. E., Cyr, N. E., et al. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00639.2010 · Cited by 36
Novel inheritance of the murine severe combined anemia and thrombocytopenia (scat) phenotype
Peters, L. L., & Barker, J. E. (1993) · Cell · doi:10.1016/0092-8674(93)90301-6 · Cited by 36
Daikoku, T., Shinohara, Y., Shima, A., Yamazaki, N., & Terada, H. (2000) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(00)00107-9 · Cited by 36
Yoshinari, K., Okino, N., SATO, T. A., Sugatani, J., & Miwa, M. (2006) · Drug Metabolism and Disposition · doi:10.1124/dmd.105.007286 · Cited by 36
Norepinephrine-dependent selection of brown adipocyte cell lines
Kozak, U. C., & Kozak, L. P. (1994) · Endocrinology · doi:10.1210/endo.134.2.7905411 · Cited by 35
Self-citationtrans-10,cis-12, but notcis-9,trans-11 CLA isomer, inhibits brown adipocyte thermogenic capacity
Rodrı́guez, E., Ribot, J., & Palou, A. (2002) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00637.2001 · Cited by 35
Interactions between the melanocortin system and the hypothalamo–pituitary–thyroid axis
Martin, N. M., Smith, K. L., Bloom, S. R., & Small, C. J. (2006) · Peptides · doi:10.1016/j.peptides.2005.01.028 · Cited by 34
Beige Fat, Adaptive Thermogenesis, and Its Regulation by Exercise and Thyroid Hormone
Phillips, K. J. (2019) · Biology · doi:10.3390/biology8030057 · Cited by 35
de Gemmis, P., Lapucci, C., Bertelli, M., Tognetto, A., Fanin, E., Vettor, R., Pagano, C., Pandolfo, M., & Fabbri, A. (2006) · Stem Cells and Development · doi:10.1089/scd.2006.15.719 · Cited by 33
Hormone-sensitive lipase in brown adipose tissue: Identification and effect of cold exposure
Holm, C., Fredrikson, G., Cannon, B., & Belfrage, P. (1987) · Bioscience Reports · doi:10.1007/bf01119481 · Cited by 33
Yoshitomi, H., Yamazaki, K., & Tanaka, I. (1999) · Biochemical Journal · doi:10.1042/bj3400397 · Cited by 33
Kim, E., Lim, S.-M., Kim, M., Yoo, S., & Kim, Y. (2017) · Nutrients · doi:10.3390/nu9101049 · Cited by 33
Evolutionary Genetics of Hypoxia and Cold Tolerance in Mammals
Zhu, K., Ge, D., Wen, Z., Xia, L., & Yang, Q. (2018) · Journal of Molecular Evolution · doi:10.1007/s00239-018-9870-8 · Cited by 35
Lladó, I., Estrany, M. E., Rodríguez, E., Amengual, B., Roca, P., & Palou, A. (2000) · International Journal of Obesity · doi:10.1038/sj.ijo.0801390 · Cited by 32
Predominant expression of the mitochondrial dicarboxylate carrier in white adipose tissue
Das, K., Lewis, R. Y., COMBATSIARIS, T. P., Lin, Y. L., Shapiro, L. S., Charron, M. J., & Scherer, P. E. (1999) · Biochemical Journal · doi:10.1042/0264-6021:3440313 · Cited by 32
Brown adipose tissue and nutritional energetics—where are we now?
Trayhurn, P. (1989) · Proceedings of The Nutrition Society · doi:10.1079/pns19890026 · Cited by 32
A micromethod for the isolation of total RNA from adipose tissue
Tavangar, K., Hoffman, A. R., & Kraemer, F. B. (1990) · Analytical Biochemistry · doi:10.1016/0003-2697(90)90572-q · Cited by 31
Genomic organization and promoter function of the mouse uncoupling protein 2 (UCP2) gene
Yamada, M., Hashida, T., Shibusawa, N., Iwasaki, T., Murakami, M., Monden, T., Satoh, T., & Mori, M. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00835-7 · Cited by 31
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Lemieux, H., & Blier, P. U. (2022) · Metabolites · doi:10.3390/metabo12040360 · Cited by 34
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Oh, W., Westmoreland, J. J., Summers, R. J., & Condie, B. G. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009758 · Cited by 30
Loss of brown adipose tissue uncoupling protein mRNA on deacclimation of cold-exposed rats
Reichling, S., Ridley, R. G., Patel, H. V., Harley, C. B., & Freeman, K. B. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(87)91470-7 · Cited by 30
Regulation of UCP2 and UCP3 by muscle disuse and physical activity in tetraplegic subjects
Hjeltnes, N., Fernström, M., Zierath, J. R., & Krook, A. (1999) · Diabetologia · doi:10.1007/s001250051233 · Cited by 29
Effect of Dietary Fats Differing in Degree of Unsaturation on Gene Expression in Rat Adipose Tissue
Takahashi, Y., & Ide, T. (1999) · Annals of Nutrition and Metabolism · doi:10.1159/000012772 · Cited by 29
Genetics of human obesity: lessons from mouse models and candidate genes
Echwald, S. M. (1999) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.1999.00494.x · Cited by 29
Shao, S., Liu, Z., Yang, Y., Zhang, M., & Yu, X. (2010) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22750 · Cited by 28
Wagner, R. A., Tabibiazar, R., Liao, A., & Quertermous, T. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.09.036 · Cited by 28
Memon, R. A., Hotamışlıgil, G. S., Wiesbrock, S. M., Uysal, K. T., Faggioni, R., Moser, A. H., Feingold, K. R., & Grünfeld, C. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(99)00195-x · Cited by 28
Expression of Lung Uncoupling Protein-2 mRNA is Modulated Developmentally and by Caloric Intake
Xiao, H., Massaro, D. J., MASSARO, G. D., & Clerch, L. B. (2004) · Experimental Biology and Medicine · doi:10.1177/153537020422900605 · Cited by 28
Sostre‐Colón, J., Uehara, K., Whitlock, A. E. G., Gavin, M. J., Ishibashi, J., Potthoff, M. J., Seale, P., & Titchenell, P. M. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109128 · Cited by 26
Kozak, L. P., Koza, R. A., Anunciado‐Koza, R. P., Mendoza, T. M., & Newman, S. S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030392 · Cited by 27
Self-citationAssociation of bovine carcass phenotypes with genes in an adaptive thermogenesis pathway
Ryu, J., Kim, Y., Kim, C., Kim, J., & Lee, C. (2011) · Molecular Biology Reports · doi:10.1007/s11033-011-0880-5 · Cited by 27
Brown Adipose Tissue and Its Uncoupling Protein in Chronically Hypoxic Rats
Mortola, J. P., & Naso, L. (1997) · Clinical Science · doi:10.1042/cs0930349 · Cited by 27
Ricquier, D., Raimbault, S., Champigny, O., Miroux, B., & Bouillaud, F. (1992) · FEBS Letters · doi:10.1016/0014-5793(92)80496-4 · Cited by 27
Sepsis Induces Adipose Tissue Browning in Nonobese Mice But Not in Obese Mice
Ayalon, I., Shen, H., Williamson, L., Stringer, K. F., Zingarelli, B., & Kaplan, J. M. (2017) · Shock · doi:10.1097/shk.0000000000001076 · Cited by 28
Eljalby, M., Huang, X., Becher, T., Wibmer, A. G., Jiang, C. S., VAUGHAN, R. D., Schöder, H. M., & Cohen, P. (2022) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00187.2022 · Cited by 26
Perinatal Activation of Brown Adipose Tissue
Cannon, B., Connolly, E. D., Obregón, M.-J., & Nedergaard, J. (1988) · Springer eBooks · doi:10.1007/978-3-642-72975-1_27 · Cited by 26
Houštěk, J., Tvrdík, P., Pavelka, S., & Baudyšová, M. (1991) · FEBS Letters · doi:10.1016/0014-5793(91)80666-q · Cited by 26
Kuusela, P., Rehnmark, S., Jacobsson, A., Cannon, B., & Nedergaard, J. (1997) · Biochemical Journal · doi:10.1042/bj3210759 · Cited by 25
Self-citation
Metadata
- Authors
- Jacobsson, A., Stadler, U., Glotzer, M. A., & Kozak, L. P.
- Affiliations
- Stockholm University (SE)
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1985-12
- Volume
- 260
- Issue
- 30
- Pages
- 16250-16254
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1513078811
- Cited by
- 300
- References
- 36
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 6 · 2021: 10 · 2020: 1 · 2019: 4 · 2018: 8 · 2017: 7 · 2016: 7 · 2015: 1 · 2014: 2 · 2013: 3 · 2012: 3
- FWCI
- 6.62
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Biological Chemistry (publishedVersion, cc-by)
- PubMed (publishedVersion)
- The Mouseion at the JAXlibrary (Jackson Laboratory) (submittedVersion)
- Funders
- National Institutes of Health
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD-08431)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Peroxisome Proliferator-Activated Receptors
- Keywords
- mitochondrial uncoupling proteins, brown adipose tissue, cold-responsive genes, cDNA cloning, gene mapping, chromosome 8, mRNA expression, cold exposure, thermoregulation, diabetic mice, recombinant inbred mouse strains, restriction fragment polymorphism
- MeSH terms
- Uncoupling Protein 1, Animals, Adipose Tissue, Brown, Carrier Proteins, Cloning, Molecular, Cold Temperature, DNA Transposable Elements, DNA, Mitochondrial, Genes, Ion Channels, Membrane Proteins, Mice, Inbred C57BL, Mice, Mutant Strains, Mitochondria, Molecular Weight, RNA, Messenger, Protein Biosynthesis, Mitochondrial Proteins, Mice
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