Health-related quality of life in patients with chronic fatigue syndrome
Abstract
Objective Chronic fatigue syndrome (CFS) has been reported worldwide. Our objectives were to determine if patients from different countries have similar profiles of impairments.Methods Health-related quality of life (HRQoL) was assessed in 740 CFS patients in the US, 82 in the UK, and 65 in Germany using the eight subscales of the Short-Form General Health Survey (SF-36). To examine the internal structure, factor analyses were performed.Results Overall, there was a remarkable similarity in HRQoL among all CFS patients, regardless of location. Patients scored two to three standard deviations below normal on six subscales and one standard deviation below normal on the other two subscales. Factor analysis suggested a two-factor model where the same six subscales constitute the first factor and the two others the second factor.Conclusion HRQoL is poor in CFS patients from three countries. This study is a first step towards conducting further comparative cross-cultural and international studies.
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QoL is lower in CFS patients compared with other chronic ill and healthy control groups.
“Research shows that the QoL is lower in CFS patients compared with other chronic ill and healthy control groups [35-37].”
From Cognitive behavior therapy in patients with chronic fatigue syndrome: The role of illness acceptance and neuroticism. (2013) · cites this paper as [35]
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Quality of Life Issues in Chronic Fatigue Syndrome
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Kartlegging av funksjon ved kronisk utmattelsessyndrom
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CHRONIC FATIGUE SYNDROME: A CROSS-CULTURAL APPROXIMATION
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- Authors
- Hardt, J., Buchwald, D., Wilks, D., Sharpe, M., Nix, W. A., & Egle, U. T.
- Affiliations
- Johannes Gutenberg University Mainz (DE)
- University of Washington (US)
- Western General Hospital (GB)
- Royal Edinburgh Hospital (GB)
- Corresponding author
- Hardt, J
- Venue
- Journal of Psychosomatic Research
- Publisher
- Elsevier BV
- Published
- 2001-08
- Volume
- 51
- Issue
- 2
- Pages
- 431-434
- ISSN
- 0022-3999 (ISSN-L)
- OpenAlex
- W156640090
- Cited by
- 86
- References
- 34
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 3 · 2022: 4 · 2021: 1 · 2020: 4 · 2019: 4 · 2018: 2 · 2017: 2 · 2016: 3 · 2015: 8 · 2014: 2 · 2013: 5 · 2012: 4
- FWCI
- 2.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychosomatic Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Bundesministerium für Gesundheit
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases (U19 AI 38429, U19AI038429)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Keywords
- chronic fatigue syndrome, health-related quality of life, SF-36, cross-cultural comparison, physical and mental impairment
- MeSH terms
- Adolescent, Aged, Cross-Sectional Studies, Factor Analysis, Statistical, Female, Health Status, Humans, Male, Middle Aged, Quality of Life, Fatigue Syndrome, Chronic
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