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Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions
Abstract
Vinyl chloride monomer (VCM) is a human carcinogen. However, the exact mechanism of carcinogenesis remains unclear. VCM may be metabolized by cytochrome P450 2E1 (CYP2E1), aldehyde dehydrogenase 2 (ALDH2) and glutathione S-transferases (GSTs). Thus workers with inherited variant metabolic enzyme activities may have an altered risk of genotoxicity. This study was designed to investigate which risk factors might affect sister chromatid exchange (SCE) frequency in polyvinyl chloride (PVC) workers. Study subjects were 44 male workers from three PVC factories. Questionnaires were administered to obtain detailed histories of cigarette smoking, alcohol consumption, occupations, and medications. SCE frequency in peripheral lymphocytes was determined using a standardized method, and CYP2E1, GSTM1, GSTT1 and ALDH2 genotypes were identified by the polymerase chain reaction (PCR). Analysis revealed that smoking status and exposure to VCM were significantly associated with increased SCE frequency. The presence of ALDH2 1-2/2-2 genotypes was also significantly associated with an elevation of SCE frequency (9. 5 vs. 8.1, p<0.01). However, CYP2E1, GSTM1 or GSTT1 genotypes were not significantly associated with SCE frequency. When various genotypes were considered together, combination of CYP2E1 c1c2/c2c2 with ALDH2 1-2/2-2 showed an additive effect on SCE frequency. Similar results were also found for the combination of smoking with CYP2E1, or smoking with ALDH2. These results suggest that VCM workers with ALDH2 1-2/2-2 genotypes, who also smoke, may have increased risk of DNA damage.
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“The most common oxidative lesions in mtDNA are the G:C to T:A transversion mutations caused by adenine pairing with the guanine adduct 7,8-dihydro-8-oxo-deoxyguanosine (8-oxo-dG) (Wang et al., 1998).”
From Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases (2017) · cites this paper as Wang et al., 1998
Citations
Cites
1 retracted
Cooper, P. K., Nouspikel, T. P., Clarkson, S. G., & Leadon, S. A. (1997) · Science · doi:10.1126/science.275.5302.990 · Cited by 306
RetractedFree radicals in biology and medicine
Gutteridge, J. M. C. (1991) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(91)90478-o · Cited by 17,178
Oxidants, antioxidants, and the degenerative diseases of aging.
Ames, B. N., Shigenaga, M. K., & Hagen, T. M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.17.7915 · Cited by 5,958
Friedberg, E. C., Walker, G. C., Siede, W., Wood, R. D., Schultz, R. A., & Ellenberger, T. (2005) · doi:10.1128/9781555816704 · Cited by 5,683
Free Radicals in Biology and Medicine
Land, E. J. (1990) · International Journal of Radiation Biology · doi:10.1080/09553009014552071 · Cited by 4,871
Bootsma, D., & Hoeijmakers, J. H. J. (1996) · Trends in Genetics · doi:10.1016/0168-9525(96)81408-9 · Cited by 2,285
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
Shibutani, S., Takeshita, M., & Grollman, A. P. (1991) · Nature · doi:10.1038/349431a0 · Cited by 2,224
The Chemical Basis of Radiation Biology
O'Neill, P. (1987) · International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine · doi:10.1080/09553008714552571 · Cited by 1,849
8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions.
Cheng, K. C., Cahill, D. S., Kasai, H., Nishimura, S., & Loeb, L. A. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48474-8 · Cited by 1,844
The chemical basis of radiation biology
von Sonntag, C. (1987) · Medical Entomology and Zoology · Cited by 1,748
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Kassam, S. N., & Rainbow, A. J. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.06.005 · Cited by 43
Sicoli, G., Mathis, G., Aci‐Sèche, S., Saint‐Pierre, C., Boulard, Y., Gasparutto, D., & Gambarelli, S. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp165 · Cited by 44
Molecular Alterations of Colorectal Cancer with Inflammatory Bowel Disease
Yashiro, M. (2015) · Digestive Diseases and Sciences · doi:10.1007/s10620-015-3646-4 · Cited by 44
Thapa, B., Munk, B. H., Burrows, C. J., & Schlegel, H. B. (2017) · Chemistry - A European Journal · doi:10.1002/chem.201700231 · Cited by 43
DNA Damage after Acute and Chronic Treatment with Malathion in Rats
Réus, G. Z., Valvassori, S. S., Nuernberg, H., Comim, C. M., Stringari, R. B., Padilha, P. T., Leffa, D. D., Tavares, P., Dagostim, G. P., Paula, M. M. D. S., et al. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf800910q · Cited by 42
XRCC1 and ERCC1 variants modify malignant mesothelioma risk: A case–control study
Betti, M., Ferrante, D., Padoan, M., Guarrera, S., Giordano, M., Aspesi, A., Mirabelli, D., Casadio, C., Ardissone, F., Ruffini, E., et al. (2011) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2011.01.001 · Cited by 43
The unexpected landscape of in vivo somatic mutation in a human epithelial cell lineage
Colgin, L. M., Hackmann, A. F. M., Emond, M. J., & Monnat, R. J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.032655699 · Cited by 43
Bruckbauer, S. T., Trimarco, J. D., Martin, J., Bushnell, B., Senn, K. A., Schackwitz, W., Lipzen, A., Blow, M. J., Wood, E. A., Culberson, W. S., et al. (2019) · Journal of Bacteriology · doi:10.1128/jb.00784-18 · Cited by 43
Zhu, Z., Jiang, W., Ganther, H. E., Ip, C. C. Y., & Thompson, H. J. (2000) · Biochemical Pharmacology · doi:10.1016/s0006-2952(00)00461-5 · Cited by 41
Overexpression of Lysosomal Acid Lipase and Other Proteins in Atherosclerosis
Zschenker, O., Illies, T., & Ameis, D. (2006) · The Journal of Biochemistry · doi:10.1093/jb/mvj137 · Cited by 40
Mutations of lysophosphatidic acid receptor-1 gene during progression of lung tumors in rats
Yamada, T., Obo, Y., Furukawa, M., Hotta, M., Yamasaki, A., Honoki, K., Fukushima, N., & Tsujiuchi, T. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.11.044 · Cited by 40
Role of mitochondria in carcinogenesis.
Tokarz, P., & Błasiak, J. (2014) · Acta Biochimica Polonica · doi:10.18388/abp.2014_1829 · Cited by 38
Morikawa, M., Kino, K., Oyoshi, T., Suzuki, M., Kobayashi, T., & Miyazawa, H. (2014) · Biomolecules · doi:10.3390/biom4010140 · Cited by 40
Genotoxic effects of glyphosate on Physalaemus tadpoles
Herek, J. S., Vargas, L., Trindade, S. A. R., Rutkoski, C. F., Macagnan, N., Hartmann, P. A., & Hartmann, M. T. (2020) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2020.103516 · Cited by 38
Kim, J. C., Gil, J. M., & Greenberg, M. M. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200352102 · Cited by 38
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Schärer, O. D. (2003) · Angewandte Chemie · doi:10.1002/ange.200200523 · Cited by 37
Prospects for applying genotypic selection of somatic oncomutation to chemical risk assessment
McKinzie, P. B. (2001) · Mutation Research/Reviews in Mutation Research · doi:10.1016/s1383-5742(01)00063-1 · Cited by 37
Regulation of mitochondrial apoptosis by Pin1 in cancer and neurodegeneration
Sorrentino, G., Comel, A., Mantovani, F., & Sal, G. D. (2014) · Mitochondrion · doi:10.1016/j.mito.2014.08.003 · Cited by 36
Reinardy, H. C., & Bodnar, A. G. (2015) · Mutagenesis · doi:10.1093/mutage/gev052 · Cited by 36
Jelínková, Š., Fojtík, P., Kohutová, A., Vilotić, A., Marková, L., Pešl, M., Juráková, T., Krutá, M., Vrbský, J., Gaillyová, R., et al. (2019) · Cells · doi:10.3390/cells8010053 · Cited by 37
Oxidative and Nitrosative Stress in the Metastatic Microenvironment
Ortega, Á., Mena, S., & Estrela, J. M. (2010) · Cancers · doi:10.3390/cancers2020274 · Cited by 36
Potent Antioxidative Activity of Vineatrol®30 Grapevine-shoot Extract
MÜLLER, C., Ullmann, K., Wilkens, A., Winterhalter, P., Toyokuni, S., & Steinberg, P. (2009) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.90213 · Cited by 36
Mutation Exposed: A Neutral Explanation for Extreme Base Composition of an Endosymbiont Genome
Wernegreen, J. J., & Funk, D. J. (2004) · Journal of Molecular Evolution · doi:10.1007/s00239-003-0192-z · Cited by 36
Patro, J. N., Haraguchi, K., Delaney, M. O., & Greenberg, M. M. (2004) · Biochemistry · doi:10.1021/bi049035s · Cited by 36
Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases
Basu, A. K., & Essigmann, J. M. (2022) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.2c00155 · Cited by 36
Self-citationTremblay, S., & Wagner, J. R. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm1013 · Cited by 35
Effect of predator stress and malathion on tadpoles of Indian skittering frog
Giri, A., Yadav, S. S., Giri, S., & Sharma, G. D. (2011) · Aquatic Toxicology · doi:10.1016/j.aquatox.2011.11.008 · Cited by 35
Effects of Peroxynitrite Dose and Dose Rate on DNA Damage and Mutation in thesupFShuttle Vector
Kim, M. Y., Dong, M., Dedon, P. C., & Wogan, G. N. (2004) · Chemical Research in Toxicology · doi:10.1021/tx049777m · Cited by 35
Chao, M., Kim, M. Y., Ye, W., Ge, J., Trudel, L. J., Belanger, C. L., Skipper, P. L., Engelward, B. P., Tannenbaum, S. R., & Wogan, G. N. (2012) · Toxicological Sciences · doi:10.1093/toxsci/kfs229 · Cited by 34
Redrejo‐Rodríguez, M., Rodríguez, J. M., Suárez, C., Salas, J., & Salas, M. L. (2013) · Journal of Virology · doi:10.1128/jvi.01173-13 · Cited by 34
Protein−RNA Cross-Linking in the Ribosomes of Yeast under Oxidative Stress
Mirzaei, H., & Regnier, F. E. (2006) · Journal of Proteome Research · doi:10.1021/pr060337l · Cited by 34
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Förster, S., & Plantenberg, T. (2002) · Angewandte Chemie · doi:10.1002/1521-3757(20020301)114:5 · Cited by 73
Nilov, D. I., Komarov, D. Y., Panov, M. S., Karabaeva, K. E., Mereshchenko, A. S., Tarnovsky, A. N., & Wilson, R. M. (2013) · Journal of the American Chemical Society · doi:10.1021/ja3068148 · Cited by 32
Soares, N. P., Santos, A. C. S. D., Costa, E. C., Azevedo, G. D., Damasceno, D. C., Fayh, A. P. T., & Lemos, T. M. A. M. (2016) · Annals of Nutrition and Metabolism · doi:10.1159/000444130 · Cited by 31
Kobets, T., Iatropoulos, M. J., & Williams, G. M. (2018) · Toxicology Research · doi:10.1039/c8tx00250a · Cited by 31
Effect of caloric restriction on Hprt lymphocyte mutation in aging rats
Aidoo, A., Mittelstaedt, R. A., Bishop, M. E., Lyn‐Cook, L. E., Chen, Y., Duffy, P. H., & Heflich, R. H. (2003) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(03)00072-1 · Cited by 31
Jiang, Y. L., Wiederholt, C. J., Patro, J. N., Haraguchi, K., & Greenberg, M. M. (2004) · The Journal of Organic Chemistry · doi:10.1021/jo048253o · Cited by 31
Matić, S. L., Stanić, S., Bogojević, D., Vidaković, M., Grdović, N., Јovanović, J. A., Dinić, S., Uskoković, A. S., Poznanović, G., Solujić, S., et al. (2011) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y11-043 · Cited by 30
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Whitehall, J. C., & Greaves, L. C. (2019) · Biogerontology · doi:10.1007/s10522-019-09853-y · Cited by 34
Wang, Y. (2002) · Chemical Research in Toxicology · doi:10.1021/tx0155855 · Cited by 30
Hydrogen peroxide induced mutations at the HPRT locus in primary human T-lymphocytes
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Patro, J. N., Urban, M., & Kuchta, R. D. (2009) · Biochemistry · doi:10.1021/bi900777s · Cited by 29
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Cabrera, G., Cabrejos, M. E., Morassutti, A. L., Cabezón, C., Orellana, J., Hellman, U., Zaha, A., & Galanti, N. (2008) · Journal of Cellular Physiology · doi:10.1002/jcp.21418 · Cited by 29
Ji, F., Wang, W., Xia, Z., Zheng, Y., Qiu, Y. L., Wu, F., Miao, W., Jin, R. F., Qian, J., Li, J., et al. (2010) · Carcinogenesis · doi:10.1093/carcin/bgq015 · Cited by 29
Rössner, P., Uhlířová, K., Beskid, O., Rössnerová, A., Švecová, V., & Šrám, R. J. (2011) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2011.06.001 · Cited by 28
[15] Ultraviolet A- and singlet oxygen-induced mutation spectra
Stary, A., & Sarasin, A. R. (2000) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(00)19017-2 · Cited by 29
Singha, U., Pandey, N., Boro, F., Giri, S., Giri, A., & Biswas, S. (2014) · Chemosphere · doi:10.1016/j.chemosphere.2014.04.076 · Cited by 28
Experimental evolution of extremophile resistance to ionizing radiation
Bruckbauer, S. T., & Cox, M. M. (2021) · Trends in Genetics · doi:10.1016/j.tig.2021.04.011 · Cited by 28
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Rajapakse, K., Drobne, D., Kastelec, D., & Marinšek-Logar, R. (2012) · Nanotoxicology · doi:10.3109/17435390.2012.696735 · Cited by 27
The Significance of 8-oxoGsn in Aging-Related Diseases
Zhang, X., & Li, L. (2020) · Aging and Disease · doi:10.14336/ad.2019.1021 · Cited by 28
Kim, J. C., Weledji, Y. N., & Greenberg, M. M. (2004) · The Journal of Organic Chemistry · doi:10.1021/jo049033d · Cited by 27
Barg, M., Rezin, G. T., Leffa, D. D., Balbinot, F., Gomes, L. M., Carvalho‐Silva, M., Vuolo, F. S., Petronilho, F. C., Dal‐Pizzol, F., STRECK, E. L., et al. (2013) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2013.11.028 · Cited by 27
Reduktiver Elektronentransfer und Transport von Überschusselektronen in DNA
Wagenknecht, H. (2003) · Angewandte Chemie · doi:10.1002/ange.200301629 · Cited by 27
Kahl, V. F. S., Reyes, J. M., Sarmento, M. D. S., & da Silva, J. (2012) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2012.01.008 · Cited by 26
Cabrera, G., Barría, C. S., Fernández, C., Sepúlveda, S., Valenzuela-Pérez, L., Kemmerling, U., & Galanti, N. (2011) · Journal of Cellular Biochemistry · doi:10.1002/jcb.23138 · Cited by 26
Lopez, C. M. R., Bravo, H. S., Wetten, A. C., & Wilkinson, M. J. (2009) · Molecular Breeding · doi:10.1007/s11032-009-9348-x · Cited by 26
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Joosen, A. M. C. P., Lecommandeur, E., Kuhnle, G., Aspinall, S. M., Kap, L., & Rodwell, S. A. (2010) · Mutagenesis · doi:10.1093/mutage/gep070 · Cited by 26
Boone, E. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.3.830 · Cited by 25
Peritz, A. E., & Gasparro, F. P. (1999) · Journal of Investigative Dermatology Symposium Proceedings · doi:10.1038/sj.jidsp.5640174 · Cited by 24
Ghude, P., Schallenberger, M. A., Fleming, A. M., Muller, J. G., & Burrows, C. J. (2010) · Inorganica Chimica Acta · doi:10.1016/j.ica.2010.12.063 · Cited by 24
Treatment of Ribonucleoside Solution With Atmospheric‐Pressure Plasma
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Oxidation of DNA Followed by Conformational Change after OH Radical Attack
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Ji, D., Beharry, A. A., Ford, J. M., & Kool, E. T. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.6b02895 · Cited by 24
Ultrafast charge transfer dynamics in 2-aminopurine modified double helical DNA
Parameswaran, M., Min, C., Aravindakumar, C. T., & Joo, T. (2008) · Chemical Physics · doi:10.1016/j.chemphys.2008.07.005 · Cited by 26
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Wen, S., Aki, T., Funakoshi, T., Unuma, K., & Uemura, K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23105418 · Cited by 25
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Lee, K. J., Kim, D. S., Kim, J., Jo, S., Kang, S., Choi, H., & Ha, B. (2016) · Molecular Genetics and Genomics · doi:10.1007/s00438-016-1183-2 · Cited by 23
Molecular mechanisms of lead toxicity
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Gasparutto, D., Muller, E., Boiteux, S., & Cadet, J. (2008) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2008.10.001 · Cited by 24
Moderate G6PD deficiency increases mutation rates in the brain of mice
Felix, K., Rockwood, L. D., Pretsch, W., Nair, J., Bartsch, H., Bornkamm, G.-W., & Janz, S. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00756-6 · Cited by 22
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Grąziewicz, M.-A., Zastawny, T. H., Oliński, R., & Tudek, B. (1999) · Mutation Research/DNA Repair · doi:10.1016/s0921-8777(99)00012-9 · Cited by 22
Kinetics and dynamics of oligonucleotide hybridization
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Prunkl, C., Berndl, S., Wanninger‐Weiß, C., Barbaric, J., & Wagenknecht, H. (2009) · Physical Chemistry Chemical Physics · doi:10.1039/b914487k · Cited by 22
Abedin, Z. R., Sen, S., & Field, J. M. (2011) · Chemical Research in Toxicology · doi:10.1021/tx200272v · Cited by 22
Electrocatalytic oxidation of nucleobases by TiO2 nanobelts
Cui, J., Sun, D., Zhou, W., Liu, H., Hu, P., Ren, N., Qin, H., Huang, Z., Lin, J., & Ma, H. (2011) · Physical Chemistry Chemical Physics · doi:10.1039/c1cp20082h · Cited by 21
Suzuki, T., Wang, X., Miyata, Y., Saeki, K., Kohara, A., Kawazoe, Y., Hayashi, M., & Sofuni, T. (2000) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(00)00128-7 · Cited by 21
2'-Deoxyribonolactone lesion produces G->A transitions in Escherichia coli
Faure, V. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh622 · Cited by 21
Wolf, P., Kreimer-Erlacher, H., Seidl, H., Bäck, B., Soyer, H. P., & Kerl, H. (2004) · Journal of Investigative Dermatology · doi:10.1046/j.0022-202x.2004.22118.x · Cited by 21
Preferential Protection of Genetic Fidelity within Open Chromatin by the Mismatch Repair Machinery
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Zhang, J., Guo, F., Wei, J., Xian, M., Tang, S., Zhao, Y., Liu, M., Song, L., Geng, Y., Yang, H., et al. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.07.002 · Cited by 20
iMARS—Mutation analysis reporting software: An analysis of spontaneous cII mutation spectra
Morgan, C., & Lewis, P. D. (2005) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2005.09.010 · Cited by 20
Adam, W., Arnold, M. A., & Saha‐Möller, C. R. (2000) · The Journal of Organic Chemistry · doi:10.1021/jo0056491 · Cited by 20
Mutagenic fingerprint of ozone in human cells
Jorge, S. (2002) · DNA repair · doi:10.1016/s1568-7864(02)00011-3 · Cited by 20
Gifford, C. M., Blaisdell, J. O., & Wallace, S. S. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.19.5416-5424.2000 · Cited by 20
Rebalancing redox homeostasis: A pivotal regulator of the cGAS-STING pathway in autoimmune diseases
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Küpfer, P. A., & Leumann, C. J. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr673 · Cited by 19
Failure of catalase to protect against aflatoxin B1-induced mouse lung tumorigenicity
Guindon, K. A., Foley, J. F., Maronpot, R. R., & Massey, T. E. (2007) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2007.10.015 · Cited by 19
UV-inducible base excision repair of oxidative damaged DNA in human cells
Kassam, S. N., & Rainbow, A. J. (2008) · Mutagenesis · doi:10.1093/mutage/gen054 · Cited by 19
Slade, P. G., Priestley, N. D., & Sugden, K. D. (2007) · Organic Letters · doi:10.1021/ol701667t · Cited by 20
Gasparutto, D., Dhérin, C., Boiteux, S., & Cadet, J. (2002) · DNA repair · doi:10.1016/s1568-7864(02)00016-2 · Cited by 20
Shane, B. S., Smith-Dunn, D. L., deBoer, J. G., Glickman, B. W., & Cunningham, M. L. (2000) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(00)00002-6 · Cited by 19
Oxidative Damage on RNA Nucleobases
Küpfer, P. A., & Leumann, C. J. (2014) · RNA technologies · doi:10.1007/978-3-642-54452-1_5 · Cited by 19
Zhang, J., Geng, Y., Guo, F., Zhang, F., Liu, M.-W., Song, L., Ma, Y., Li, D., Zhang, Y., Xu, H., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-10131-5 · Cited by 18
Tajai, P., Fedeles, B. I., Suriyo, T., Navasumrit, P., Kanitwithayanun, J., Essigmann, J. M., & Satayavivad, J. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.12.035 · Cited by 18
Self-citation
Metadata
- Authors
- Wang, D., Kreutzer, D. A., & Essigmann, J. M.
- Affiliations
- Massachusetts Institute of Technology (US)
- Corresponding author
- Essigmann, John M.
- Venue
- Mutation research. Fundamental and molecular mechanisms of mutagenesis
- Publisher
- Elsevier BV
- Published
- 1998-05
- Volume
- 400
- Issue
- 1-2
- Pages
- 99-115
- ISSN
- 0027-5107 (ISSN-L)
- 1386-1964
- OpenAlex
- W2009187135
- Cited by
- 464
- References
- 179
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 5 · 2023: 5 · 2022: 8 · 2021: 8 · 2020: 9 · 2019: 11 · 2018: 10 · 2017: 15 · 2016: 14 · 2015: 19 · 2014: 21 · 2013: 21 · 2012: 22
- FWCI
- 6.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Mutation research. Fundamental and molecular mechanisms of mutagenesis (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Carcinogens and Genotoxicity Assessment
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA and Nucleic Acid Chemistry
- Keywords
- oxidative DNA damage, mutagenicity, DNA repair, reactive oxygen species, mutational spectra, G:C to T:A transversions, G:C to A:T transitions, DNA adducts, mutational specificity, carcinogenesis, aging
- MeSH terms
- Animals, DNA Damage, DNA Mutational Analysis, DNA Repair, Humans, Oxidation-Reduction, Mutagenesis, Site-Directed, Reactive Oxygen Species, DNA Adducts
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