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The Heme Catabolic Pathway and its Protective Effects on Oxidative Stress‐Mediated Diseases

·2007·Advances in Clinical Chemistry

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  1. Schwertner, 1994, Association of low serum concentration of bilirubin with increased risk of coronary artery disease, Clin Chem, 40, 18, 10.1093/clinchem/40.1.18 · DOI · Paper page
  2. Stocker, 1987, Bilirubin is an antioxidant of possible physiological importance, Science, 235, 1043, 10.1126/science.3029864 · DOI · Paper page
  3. Neuzil, 1994, Free and albumin‐bound bilirubin are efficient co‐antioxidants for α‐tocopherol, inhibiting plasma and low density lipoprotein lipid peroxidation, J Biol Chem, 269, 16712, 10.1016/S0021-9258(19)89449-8 · DOI · Paper page
  4. Wu, 1996, Antioxidation of human low density lipoprotein by unconjugated and conjugated bilirubins, Biochem Pharmacol, 51, 859, 10.1016/0006-2952(95)02395-X · DOI · Paper page
  5. Willis, 1996, Heme oxygenase: A novel target for the modulation of the inflammatory response, Nature Med, 2, 87, 10.1038/nm0196-87 · DOI · Paper page
  6. Nakagami, 1993, A beneficial role of bile pigments as an endogenous tissue protector: Anticomplement effects of biliverdin and conjugated bilirubin, Biochim Biophys Acta, 1158, 189, 10.1016/0304-4165(93)90013-X · DOI · Paper page
  7. Rigato, 2005, Bilirubin and the risk of common non‐hepatic diseases, Trends Mol Med, 11, 277, 10.1016/j.molmed.2005.04.008 · DOI
  8. Kapitulnik, 2004, Bilirubin: An endogenous product of heme degradation with both cytotoxic and cytoprotective properties, Mol Pharmacol, 66, 773, 10.1124/mol.104.002832 · DOI · Paper page
  9. Abraham, 2005, Heme oxygenase and the cardiovascular‐renal system, Free Radic Biol Med, 39, 1, 10.1016/j.freeradbiomed.2005.03.010 · DOI · Paper page
  10. Maines, 1997, The heme oxygenase system: A regulator of second messenger gases, Annu Rev Pharmacol Toxicol, 37, 517, 10.1146/annurev.pharmtox.37.1.517 · DOI · Paper page
  11. Rodgers, 1990, Developmental biology of heme oxygenase, Clin Perinatol, 17, 275, 10.1016/S0095-5108(18)30568-2 · DOI
  12. Nath, 1994, The functional significance of induction of heme oxygenase by oxidant stress, J Lab Clin Med, 123, 461
  13. Valaes, 1990, Pharmacologic approaches to the prevention and treatment of neonatal hyperbilirubinemia, Clin Perinatol, 17, 245, 10.1016/S0095-5108(18)30567-0 · doi:10.1016/s0095-5108(18)30567-0
  14. Pannen, 1998, Differential regulation of hepatic arterial and portal venous vascular resistance by nitric oxide and carbon monoxide in rats, Life Sci, 62, 2025, 10.1016/S0024-3205(98)00174-X · DOI
  15. Leffler, 1999, Carbon monoxide and cerebral microvascular tone in newborn pigs, Am J Physiol, 276, H1641
  16. Amersi, 1999, Upregulation of heme oxygenase‐1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury, J Clin Invest, 104, 1631, 10.1172/JCI7903 · DOI · Paper page
  17. Coito, 2002, Heme oxygenase‐1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia‐reperfusion injury, Transplantation, 74, 96, 10.1097/00007890-200207150-00017 · DOI
  18. Raju, 1999, Chamber‐specific regulation of heme oxygenase‐1 (heat shock protein 32) in right‐sided congestive heart failure, J Mol Cell Cardiol, 31, 1581, 10.1006/jmcc.1999.0995 · DOI
  19. Sharma, 1996, Coordinated expression of heme oxygenase‐1 and ubiquitin in the porcine heart subjected to ischemia and reperfusion, Mol Cell Biochem, 157, 111, 10.1007/BF00227888 · DOI
  20. Raju, 1996, Renal ischemia/reperfusion up‐regulates heme oxygenase‐1 (HSP32) expression and increases cGMP in rat heart, J Pharmacol Exp Ther, 277, 1814, 10.1016/S0022-3565(25)13138-8 · DOI
  21. Attuwaybi, 2004, Heme oxygenase‐1 induction by hemin protects against gut ischemia/reperfusion injury, J Surg Res, 118, 53, 10.1016/j.jss.2004.01.010 · DOI
  22. Ishizaka, 1997, Angiotensin II‐induced hypertension increases heme oxygenase‐1 expression in rat aorta, Circulation, 96, 1923, 10.1161/01.CIR.96.6.1923 · DOI
  23. Yang, 2004, Heme oxygenase‐1 gene expression modulates angiotensin II‐induced increase in blood pressure, Hypertension, 43, 1221, 10.1161/01.hyp.0000126287.62060.e6 · DOI
  24. Sharma, 1985, Serum unconjugated bilirubin and free fatty acids in acute myocardial infarction and angina, J Assoc Physicians India, 33, 473
  25. Dohi, 2003, Transient elevation of serum bilirubin (a heme oxygenase‐1 metabolite) level in hemorrhagic stroke: Bilirubin is a marker of oxidant stress, Acta Neurochir Suppl, 86, 247
  26. Dohi, 2005, Elevated plasma levels of bilirubin in patients with neurotrauma reflect its pathophysiological role in free radical scavenging, In Vivo, 19, 855
  27. Wang, 1998, Expression of heme oxygenase‐1 in atherosclerotic lesions, Am J Pathol, 152, 711
  28. Ishikawa, 1997, Induction of heme oxygenase‐1 inhibits the monocyte transmigration induced by mildly oxidized LDL, J Clin Invest, 100, 1209, 10.1172/JCI119634 · DOI · Paper page
  29. Abraham, 1995, Transfection of the human gene heme oxygenase gene into rabbit coronary microvessel endothelial cells: Protective effect against heme and hemoglobin toxicity, Proc Natl Acad Sci USA, 92, 6798, 10.1073/pnas.92.15.6798 · DOI · Paper page
  30. Balla, 1991, Hemin: A possible physiological mediator of low density lipoprotein oxidation and endothelial injury, Arterioscler Thromb, 11, 1700, 10.1161/01.ATV.11.6.1700 · DOI · Paper page
  31. Hanckock, 1998, Antibody‐induced transplant arteriosclerosis is prevented by graft expression of antioxidant and antiapoptotic genes, Nat Med, 4, 1392, 10.1038/3982 · DOI · Paper page
  32. Soares, 1998, Expression of heme oxygenase‐1 can determine cardiac xenograft survival, Nat Med, 4, 1073, 10.1038/2063 · DOI · Paper page
  33. Tsui, 2003, Prevention of chronic deterioration of heart allograft by recombinant adeno‐associated virus‐mediated heme oxygenase‐1 gene transfer, Circulation, 107, 2623, 10.1161/01.CIR.0000066911.03770.8D · DOI
  34. Braudeau, 2004, Induction of long‐term cardiac allograft survival by heme oxygenase‐1 gene transfer, Gene Ther, 11, 701, 10.1038/sj.gt.3302208 · DOI
  35. Sato, 2001, Carbon monoxide generated by heme oxygenase‐1 suppresses the rejection of mouse‐to‐rat cardiac transplants, J Immunol, 166, 4185, 10.4049/jimmunol.166.6.4185 · DOI · Paper page
  36. Araujo, 2003, Systemic rather than local heme oxygenase‐1 overexpression improves cardiac allograft outcomes in a new transgenic mouse, J Immunol, 171, 1572, 10.4049/jimmunol.171.3.1572 · DOI
  37. Bouchet, 2002, Inhibition of graft arteriosclerosis development in rat aortas following heme oxygenase‐1 gene transfer, Transpl Immunol, 9, 235, 10.1016/S0966-3274(02)00037-0 · DOI
  38. Kato, 2003, Bilirubin rinse: A simple protectant against the rat liver graft injury mimicking heme oxygenase‐1 preconditioning, Hepatology, 38, 364, 10.1053/jhep.2003.50300 · DOI
  39. Ke, 2003, Cytoprotective and antiapoptotic effects of IL‐13 in hepatic cold ischemia/reperfusion injury are heme oxygenase‐1 dependent, Am J Transplant, 3, 1076, 10.1034/j.1600-6143.2003.00147.x · DOI
  40. Ishikawa, 2001, Heme oxygenase‐1 inhibits atherosclerotic lesion formation in LDL‐receptor knockout mice, Circ Res, 88, 506, 10.1161/01.RES.88.5.506 · DOI · Paper page
  41. Ishikawa, 2001, Heme oxygenase‐1 inhibits atherogenesis in Watanabe heritable hyperlipidemic rabbits, Circulation, 104, 1831, 10.1161/hc3901.095897 · DOI
  42. Juan, 2001, Adenovirus‐mediated heme oxygenase‐1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E‐deficient mice, Circulation, 104, 1519, 10.1161/hc3801.095663 · DOI · Paper page
  43. Nakayama, 2001, Increased expression of heme oxygenase‐1 and bilirubin accumulation in foam cells of rabbit atherosclerotic lesions, Arterioscler Thromb Vasc Biol, 21, 1373, 10.1161/hq0801.093592 · DOI
  44. Duckers, 2001, Heme oxygenase‐1 protects against vascular constriction and proliferation, Nat Med, 7, 693, 10.1038/89068 · DOI · Paper page
  45. Tsui, 2005, rAAV‐mediated stable expression of heme oxygenase‐1 in stellate cells: A new approach to attenuate liver fibrosis in rats, Hepatology, 42, 335, 10.1002/hep.20803 · DOI
  46. Otterbein, 1999, Exogenous administration of heme oxygenase‐1 by gene transfer provides protection against hyperoxia‐induced lung injury, J Clin Invest, 103, 1047, 10.1172/JCI5342 · DOI · Paper page
  47. Yang, 1999, Retrovirus‐mediated HO gene transfer into endothelial cells protects against oxidant‐induced injury, Am J Physiol, 277, L127
  48. Wang, 2001, Protective role of heme oxygenase‐1 on trinitrobenzene sulfonic acid‐induced colitis in rats, Am J Physiol Gastrointest Liver Physiol, 281, G586, 10.1152/ajpgi.2001.281.2.G586 · DOI
  49. Berberat, 2005, Heme‐oxygenase‐1‐generated biliverdin ameliorates experimental murine colitis, Inflamm Bowel Dis, 11, 350, 10.1097/01.MIB.0000164017.06538.8a · DOI
  50. Guo, 2003, Expression and activities of three inducible enzymes in the healing of gastric ulcers in rats, World J Gastroenterol, 9, 1767, 10.3748/wjg.v9.i8.1767 · DOI
  51. Lee, 2002, Heme oxygenase‐1 mediates the anti‐inflammatory effect of interleukin‐10 in mice, Nat Med, 8, 240, 10.1038/nm0302-240 · DOI · Paper page
  52. Balla, 1992, Ferritin: A cytoprotective antioxidant stratagem of endothelium, J Biol Chem, 267, 18148, 10.1016/S0021-9258(19)37165-0 · DOI · Paper page
  53. Exner, 2004, The role of heme oxygenase‐1 promoter polymorphisms in human disease, Free Radic Biol Med, 37, 1097, 10.1016/j.freeradbiomed.2004.07.008 · DOI · Paper page
  54. Okinaga, 1996, Regulation of human heme oxygenase‐1 gene expression under thermal stress, Blood, 87, 5074, 10.1182/blood.V87.12.5074.bloodjournal87125074 · DOI
  55. Chen, 2002, Microsatellite polymorphism in promoter of heme‐oxygenase‐1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients, Hum Genet, 111, 1, 10.1007/s00439-002-0769-4 · DOI · Paper page
  56. Hirai, 2003, Microsatellite polymorphism in heme oxygenase‐1 gene promoter is associated with susceptibility to oxidant‐induced apoptosis in lymphoblastoid cell lines, Blood, 102, 1619, 10.1182/blood-2002-12-3733 · DOI · Paper page
  57. Yamada, 2000, Microsatellite polymorphism in the heme oxygenase‐1 gene promoter is associated with susceptibility to emphysema, Am J Hum Genet, 66, 187, 10.1086/302729 · DOI · Paper page
  58. Yamaya, 2003, Relationship between microsatellite polymorphism in the haem oxygenase‐1 gene promoter and longevity of the normal Japanese population, J Med Genet, 40, 146, 10.1136/jmg.40.2.146 · DOI
  59. He, 2002, Antioxidant gene polymorphisms and susceptibility to a rapid decline in lung function in smokers, Am J Respir Crit Care Med, 166, 323, 10.1164/rccm.2111059 · DOI · Paper page
  60. Schillinger, 2002, Heme oxygenase‐1 gene promoter polymorphism is associated with abdominal aortic aneurysm, Thromb Res, 106, 131, 10.1016/S0049-3848(02)00100-7 · DOI
  61. Exner, 2001, Heme oxygenase‐1 microsatellite gene promoter polymorphism is associated with restenosis after percutaneous transluminal angioplasty, J Endovasc Ther, 8, 433, 10.1177/152660280100800501 · DOI · Paper page
  62. Schillinger, 2004, Heme oxygenase‐1 genotype and restenosis after balloon angioplasty: A novel vascular protective factor, J Am Coll Cardiol, 43, 950, 10.1016/j.jacc.2003.09.058 · DOI
  63. Funk, 2004, The effect of a promoter polymorphism in the heme oxygenase‐1 gene on the risk of ischaemic cerebrovascular events: The influence of other vascular risk factors, Thromb Res, 113, 217, 10.1016/j.thromres.2004.03.003 · doi:10.1016/j.thromres.2004.03.003
  64. Endler, 2004, A microsatellite polymorphism in the heme oxygenase‐1 gene promoter is associated with increased bilirubin and HDL levels but not with coronary artery disease, Thromb Haemost, 91, 155, 10.1160/TH03-05-0291 · DOI
  65. Dick, 2005, Haem oxygenase‐1 genotype and cardiovascular adverse events in patients with peripheral artery disease, Eur J Clin Invest, 35, 731, 10.1111/j.1365-2362.2005.01580.x · DOI
  66. Kaneda, 2002, Heme oxygenase‐1 gene promoter polymorphism is associated with coronary artery disease in Japanese patients with coronary risk factors, Arterioscler Thromb Vasc Biol, 22, 1680, 10.1161/01.ATV.0000033515.96747.6F · DOI
  67. Chen, 2004, Heme oxygenase‐1 gene promotor microsatellite polymorphism is associated with angiographic restenosis after coronary stenting, Eur Heart J, 25, 39, 10.1016/j.ehj.2003.10.009 · DOI
  68. Gulesserian, 2005, Clinical restenosis after coronary stent implantation is associated with the heme oxygenase‐1 gene promoter polymorphism and the heme oxygenase‐1 +99G/C variant, Clin Chem, 51, 1661, 10.1373/clinchem.2005.051581 · DOI
  69. Li, 2005, Inflammatory response to coronary artery bypass surgery: Does the heme‐oxygenase‐1 gene microsatellite polymorphism play a role?, Chin Med J, 118, 1285
  70. Li, 2005, The microsatellite polymorphism of heme oxygenase‐1 is associated with baseline plasma IL‐6 level but not with restenosis after coronary in‐stenting, Chin Med J, 118, 1525
  71. Baan, 2004, Fundamental role for HO‐1 in the self‐protection of renal allografts, Am J Transpl, 4, 811, 10.1111/j.1600-6143.2004.00420.x · DOI
  72. Exner, 2004, Donor heme oxygenase‐1 genotype is associated with renal allograft function, Transplantation, 77, 538, 10.1097/01.TP.0000113467.36269.F8 · DOI
  73. Ullrich, 2005, Microsatellite polymorphism in the heme oxygenase‐1 gene promoter and cardiac allograft vasculopathy, J Heart Lung Transplant, 24, 1600, 10.1016/j.healun.2004.11.009 · DOI
  74. Ono, 2003, Association of a promoter variant of the haeme oxygenase‐1 gene with hypertension in women, J Hypertens, 21, 1497, 10.1097/00004872-200308000-00013 · DOI
  75. Ono, 2004, A promoter variant of heme oxygenase‐1 gene may reduce the incidence of ischemic heart disease in Japanese, Atherosclerosis, 173, 315, 10.1016/j.atherosclerosis.2003.11.021 · DOI
  76. Takeda, 2005, Microsatellite polymorphism in the heme oxygenase‐1 gene promoter is associated with susceptibility to cerebral malaria in Myanmar, Jpn J Infect Dis, 58, 268, 10.7883/yoken.JJID.2005.268 · DOI
  77. Shibahara, 2003, The heme oxygenase dilemma in cellular homeostasis: New insights for the feedback regulation of heme catabolism, Tohoku J Exp Med, 200, 167, 10.1620/tjem.200.167 · DOI
  78. Kanai, 2003, Neonatal hyperbilirubinemia in Japanese neonates: Analysis of the heme oxygenase‐1 gene and fetal hemoglobin composition in cord blood, Pediatr Res, 54, 165, 10.1203/01.PDR.0000072329.56635.35 · doi:10.1203/01.pdr.0000072329.56635.35
  79. Baranano, 2002, Biliverdin reductase: A major physiologic cytoprotectant, Proc Natl Acad Sci USA, 99, 16093, 10.1073/pnas.252626999 · DOI · Paper page
  80. Denschlag, 2004, The size of a microsatellite polymorphism of the haem oxygenase 1 gene is associated with idiopathic recurrent miscarriage, Mol Hum Reprod, 10, 211, 10.1093/molehr/gah024 · DOI
  81. Kanai, 2003, Polymorphisms of heme oxygenase‐1 and bilirubin UDP‐glucuronosyltransferase genes are not associated with Kawasaki disease susceptibility, Tohoku J Exp Med, 200, 155, 10.1620/tjem.200.155 · doi:10.1620/tjem.200.155
  82. Kimpara, 1997, Microsatellite polymorphism in the human heme oxygenase‐1 gene promoter and its application in association studies with Alzheimer and Parkinson disease, Hum Genet, 100, 145, 10.1007/s004390050480 · DOI · Paper page
  83. Aizawa, 2001, Differential effects of angiotensin II and catecholamine on renal cell apoptosis and proliferation in rats, Kidney Int, 59, 645, 10.1046/j.1523-1755.2001.059002645.x · DOI
  84. Lee, 1996, Overexpression of heme oxygenase‐1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia, Proc Natl Acad Sci USA, 93, 10393, 10.1073/pnas.93.19.10393 · DOI · Paper page
  85. Kikuchi, 2005, Association of susceptibility to the development of lung adenocarcinoma with heme oxygenase‐1 gene promoter polymorphism, Hum Genet, 116, 354, 10.1007/s00439-004-1162-2 · DOI
  86. Tsuji, 1999, Heme oxygenase‐1 expression in oral squamous cell carcinoma as involved in lymph node metastasis, Cancer Lett, 138, 53, 10.1016/S0304-3835(98)00372-3 · DOI
  87. Yanagawa, 2004, Heme oxygenase‐1 expression predicts cervical lymph node metastasis of tongue squamous cell carcinomas, Oral Oncol, 40, 21, 10.1016/S1368-8375(03)00128-3 · DOI
  88. Chang, 2004, Polymorphism in heme oxygenase‐1 (HO‐1) promoter is related to the risk of oral squamous cell carcinoma occurring on male areca chewers, Br J Cancer, 91, 1551, 10.1038/sj.bjc.6602186 · DOI
  89. Durante, 2003, Heme oxygenase‐1 in growth control and clinical application to vascular disease, J Cell Physiol, 195, 373, 10.1002/jcp.10274 · DOI
  90. Fang, 2004, Antiapoptotic role of heme oxygenase (HO) and the potential of HO as a target in anticancer treatment, Apoptosis, 9, 27, 10.1023/B:APPT.0000012119.83734.4e · DOI · Paper page
  91. Abraham, 2003, Human heme oxygenase: Cell cycle‐dependent expression and DNA microarray identification of multiple gene responses after transduction of endothelial cells, J Cell Biochem, 90, 1098, 10.1002/jcb.10736 · DOI
  92. Furchgott, 1991, Endothelium‐dependent and independent vasodilatation involving cyclic GMP: Relaxation induced by nitric oxide, carbon monoxide and light, Blood Vessel, 28, 52
  93. Brune, 1987, Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase, Mol Pharmacol, 32, 497, 10.1016/S0026-895X(25)13029-0 · DOI · Paper page
  94. Morita, 1995, Endothelial cell expression of vasoconstrictors and growth factors is regulated by smooth muscle cell‐derived carbon monoxide, J Clin Invest, 96, 2676, 10.1172/JCI118334 · DOI · Paper page
  95. Soares, 2002, Modulation of endothelial cell apoptosis by heme oxygenase‐1‐derived carbon monoxide, Antioxid Redox Signal, 4, 321, 10.1089/152308602753666370 · DOI
  96. Song, 2004, Carbon monoxide inhibits T lymphocyte proliferation via caspase‐dependent pathway, J Immunol, 172, 1220, 10.4049/jimmunol.172.2.1220 · DOI
  97. Stanford, 2003, Heme oxygenase is expressed in human pulmonary artery smooth muscle where carbon monoxide has an anti‐proliferative role, Eur J Pharmacol, 473, 135, 10.1016/S0014-2999(03)02001-6 · DOI
  98. Song, 2002, Carbon monoxide inhibits human airway smooth muscle cell proliferation via mitogen‐activated protein kinase pathway, Am J Respir Cell Mol Biol, 27, 603, 10.1165/rcmb.4851 · DOI
  99. Amersi, 2002, Ex vivo exposure to carbon monoxide prevents hepatic ischemia/reperfusion injury through p38 MAP kinase pathway, Hepatology, 35, 815, 10.1053/jhep.2002.32467 · DOI · Paper page
  100. Liu, 1998, Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5′ enhancer, J Biol Chem, 273, 15257, 10.1074/jbc.273.24.15257 · DOI · Paper page
  101. Morse, 2003, Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP‐1, J Biol Chem, 278, 36993, 10.1074/jbc.M302942200 · DOI · Paper page
  102. Chauveau, 2002, Gene transfer of heme oxygenase‐1 carbon monoxide delivery inhibit chronic rejection, Am J Transplant, 2, 581, 10.1034/j.1600-6143.2002.20702.x · DOI
  103. Otterbein, 2003, Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury, Nat Med, 9, 183, 10.1038/nm817 · DOI · Paper page
  104. Ke, 2002, Heme oxygenase 1 gene transfer prevents CD95/Fas ligand‐mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway, Hum Gene Ther, 13, 1189, 10.1089/104303402320138970 · DOI
  105. Henningsson, 1999, Heme oxygenase and carbon monoxide: Regulatory roles in islet hormone release: A biochemical, immunohistochemical, and confocal microscopic study, Diabetes, 48, 66, 10.2337/diabetes.48.1.66 · DOI
  106. Paredi, 1999, Exhaled carbon monoxide levels elevated in diabetes and correlated with glucose concentration in blood: A new test for monitoring the disease?, Chest, 116, 1007, 10.1378/chest.116.4.1007 · DOI
  107. Zayasu, 1997, Increased carbon monoxide in exhaled air of asthmatic patients, Am J Respir Crit Care Med, 156, 1140, 10.1164/ajrccm.156.4.96-08056 · DOI · Paper page
  108. Paredi, 1999, Increased carbon monoxide in exhaled air of patients with cystic fibrosis, Thorax, 54, 917, 10.1136/thx.54.10.917 · DOI
  109. Scharte, 2000, Increased carbon monoxide in exhaled air of critically ill patients, Biochem Biophys Res Commun, 267, 423, 10.1006/bbrc.1999.1936 · DOI
  110. Song, 2003, Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti‐inflammatory and anti‐apoptotic effects, Am J Pathol, 163, 231, 10.1016/S0002-9440(10)63646-2 · DOI · Paper page
  111. Gunther, 2002, Carbon monoxide protects pancreatic beta‐cells from apoptosis and improves islet function/survival after transplantation, Diabetes, 51, 994, 10.2337/diabetes.51.4.994 · DOI
  112. Wang, 2005, Donor treatment with carbon monoxide can yield islet allograft survival and tolerance, Diabetes, 54, 1400, 10.2337/diabetes.54.5.1400 · DOI
  113. Neto, 2004, Protection of transplant‐induced renal ischemia‐reperfusion injury with carbon monoxide, Am J Physiol Renal Physiol, 287, F979, 10.1152/ajprenal.00158.2004 · DOI · Paper page
  114. Neto, 2006, Low‐dose carbon monoxide inhalation prevents development of chronic allograft nephropathy, Am J Physiol Renal Physiol, 290, F324, 10.1152/ajprenal.00026.2005 · DOI
  115. Nakao, 2005, Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both, Am J Transplant, 5, 282, 10.1111/j.1600-6143.2004.00695.x · DOI · Paper page
  116. Sass, 2003, Heme oxygenase‐1 and its reaction product, carbon monoxide, prevent inflammation‐related apoptotic liver damage in mice, Hepatology, 38, 909
  117. Sass, 2004, Cooperative effect of biliverdin and carbon monoxide on survival of mice in immune‐mediated liver injury, Hepatology, 40, 1128, 10.1002/hep.20450 · DOI
  118. Abraham, 2003, Is smoking an indirect risk factor for the development of ulcerative colitis? An age‐ and sex‐matched case‐control study, J Gastroenterol Hepatol, 18, 139, 10.1046/j.1440-1746.2003.02953.x · doi:10.1046/j.1440-1746.2003.02953.x
  119. Mitchell, 2002, Cigarette smoking, appendectomy, and tonsillectomy as risk factors for the development of primary sclerosing cholangitis: A case control study, Gut, 51, 567, 10.1136/gut.51.4.567 · DOI
  120. Conde‐Agudelo, 1999, Cigarette smoking during pregnancy and risk of preeclampsia: A systematic review, Am J Obstet Gynecol, 181, 1026, 10.1016/S0002-9378(99)70341-8 · DOI · Paper page
  121. Allam, 2003, Parkinson's disease, smoking and family history: Meta‐analysis, Eur J Neurol, 10, 59, 10.1046/j.1468-1331.2003.00512.x · DOI
  122. Otterbein, 1999, Carbon monoxide provides protection against hyperoxic lung injury, Am J Physiol, 276, L688
  123. Fujita, 2001, Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis, Nat Med, 7, 598, 10.1038/87929 · DOI · Paper page
  124. Nakao, 2003, Carbon monoxide inhalation protects rat intestinal grafts from ischemia/reperfusion injury, Am J Pathol, 163, 1587, 10.1016/S0002-9440(10)63515-8 · DOI · Paper page
  125. Zhou, 2005, Carbon monoxide suppresses bleomycin‐induced lung fibrosis, Am J Pathol, 166, 27, 10.1016/S0002-9440(10)62229-8 · DOI
  126. Kyokane, 2001, Carbon monoxide from heme catabolism protects against hepatobiliary dysfunction in endotoxin‐treated rat liver, Gastroenterology, 120, 1227, 10.1053/gast.2001.23249 · DOI · Paper page
  127. Sarady, 2004, Carbon monoxide protection against endotoxic shock involves reciprocal effects on iNOS in the lung and liver, FASEB J, 18, 854, 10.1096/fj.03-0643fje · DOI · Paper page
  128. Moore, 2003, Inhaled carbon monoxide suppresses the development of postoperative ileus in the murine small intestine, Gastroenterology, 124, 377, 10.1053/gast.2003.50060 · DOI
  129. Moore, 2005, Brief inhalation of low‐dose carbon monoxide protects rodents and swine from postoperative ileus, Crit Care Med, 33, 1317, 10.1097/01.CCM.0000166349.76514.40 · DOI
  130. Nakao, 2003, Immunomodulatory effects of inhaled carbon monoxide on rat syngeneic small bowel graft motility, Gut, 52, 1278, 10.1136/gut.52.9.1278 · DOI
  131. Zuckerbraun, 2005, Carbon monoxide protects against the development of experimental necrotizing enterocolitis, Am J Physiol Gastrointest Liver Physiol, 289, G607, 10.1152/ajpgi.00055.2005 · DOI
  132. Motterlini, 2002, Carbon monoxide‐releasing molecules: Characterization of biochemical and vascular activities, Circ Res, 90, E17, 10.1161/hh0202.104530 · DOI · Paper page
  133. Foresti, 2004, Vasoactive properties of CORM‐3, a novel water‐soluble carbon monoxide‐releasing molecule, Br J Pharmacol, 142, 453, 10.1038/sj.bjp.0705825 · DOI · Paper page
  134. Clark, 2003, Cardioprotective actions by a water‐soluble carbon monoxide‐releasing molecule, Circ Res, 93, e2, 10.1161/01.RES.0000084381.86567.08 · DOI · Paper page
  135. Guo, 2004, Administration of a CO‐releasing molecule at the time of reperfusion reduces infarct size in vivo, Am J Physiol Heart Circ Physiol, 286, H1649, 10.1152/ajpheart.00971.2003 · DOI · Paper page
  136. Stein, 2005, Administration of a CO‐releasing molecule induces late preconditioning against myocardial infarction, J Mol Cell Cardiol, 38, 127, 10.1016/j.yjmcc.2004.10.006 · DOI
  137. Vera, 2005, Protective effect of carbon monoxide‐releasing compounds in ischemia‐induced acute renal failure, J Am Soc Nephrol, 16, 950, 10.1681/ASN.2004090736 · DOI
  138. Maines, 2005, New insights into biliverdin reductase functions: Linking heme metabolism to cell signaling, Physiology, 20, 382, 10.1152/physiol.00029.2005 · DOI
  139. Kravets, 2004, Biliverdin reductase, a novel regulator for induction of activating transcription factor‐2 and heme oxygenase‐1, J Biol Chem, 279, 19916, 10.1074/jbc.M314251200 · DOI
  140. Maines, 2001, Nuclear localization of biliverdin reductase in the rat kidney: Response to nephrotoxins that induce heme oxygenase‐1, J Pharmacol Exp Ther, 296, 1091, 10.1016/S0022-3565(24)38855-X · DOI
  141. Ahmad, 2002, Human biliverdin reductase is a leucine zipper‐like DNA‐binding protein and functions in transcriptional activation of heme oxygenase‐1 by oxidative stress, J Biol Chem, 277, 9226, 10.1074/jbc.M108239200 · DOI
  142. Lerner‐Marmarosh, 2005, Human biliverdin reductase: A member of the insulin receptor substrate family with serine/threonine/tyrosine kinase activity, Proc Natl Acad Sci USA, 102, 7109, 10.1073/pnas.0502173102 · DOI · Paper page
  143. Salim, 2001, Human biliverdin reductase is autophosphorylated, and phosphorylation is required for bilirubin formation, J Biol Chem, 276, 10929, 10.1074/jbc.M010753200 · DOI
  144. Liu, 2006, Biliverdin reductase, a major physiologic cytoprotectant, suppresses experimental autoimmune encephalomyelitis, Free Radic Biol Med, 40, 960, 10.1016/j.freeradbiomed.2005.07.021 · DOI
  145. Colpaert, 2002, Immunohistochemical localization of the antioxidant enzymes biliverdin reductase and heme oxygenase‐2 in human and pig gastric fundus, Free Radic Biol Med, 32, 630, 10.1016/S0891-5849(02)00754-2 · DOI
  146. Ewing, 1993, Biliverdin reductase is heat resistant and coexpressed with constitutive and heat shock forms of heme oxygenase in brain, J Neurochem, 61, 1015, 10.1111/j.1471-4159.1993.tb03615.x · DOI
  147. Magnusson, 2000, Heme oxygenase‐1, heme oxygenase‐2 and biliverdin reductase in peripheral ganglia from rat, expression and plasticity, Neuroscience, 95, 821, 10.1016/S0306-4522(99)00466-2 · doi:10.1016/s0306-4522(99)00466-2
  148. Phelan, 1998, Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin, Arch Biochem Biophys, 357, 155, 10.1006/abbi.1998.0814 · DOI · Paper page
  149. Puga, 2002, Role of the aryl hydrocarbon receptor in cell cycle regulation, Toxicology, 181–182, 171, 10.1016/S0300-483X(02)00276-7 · DOI
  150. Bernard, 1954, Über eine biologische bedeutung der gallenfarbstoffe: Bilirubin und biliverdin als antioxydantien für das vitamin A und die essentiellen Fettsäuren, Helv Chim Acta, 37, 306, 10.1002/hlca.19540370139 · DOI
  151. Beer, 1959, Einfluss von bilirubin und vitamin E auf die oxidation ungesättigter Fettsäuren durch UV‐bestrahlung, Chimia, 13, 291, 10.2533/chimia.1959.291 · doi:10.2533/chimia.1959.291
  152. Onishi, 1971, Photochemical and photobiological studies on the light‐treated newborn infant, Perinatology, 1, 373
  153. Onishi, 1988, Pathophysiological significance of bilirubin in neonatal jaundice as a defense mechanism against active oxygen during perinatal period, Tanpakushitsu Kakusan Koso, 33, 3005
  154. Onishi, 1989, Effect of the binding of bilirubin to either the first class or the second class of binding sites of the human serum albumin molecule on its photochemical reaction, Biochem J, 257, 711, 10.1042/bj2570711 · doi:10.1042/bj2570711
  155. McDonagh, 1971, The role of singlet oxygen in bilirubin photo‐oxidation, Biochem Biophys Res Commun, 44, 1306, 10.1016/S0006-291X(71)80228-0 · doi:10.1016/s0006-291x(71)80228-0
  156. McDonagh, 1972, Evidence for singlet oxygen quenching by biliverdin IX‐alpha dimethyl ester and its relevance to bilirubin photo‐oxidation, Biochem Biophys Res Commun, 48, 408, 10.1016/S0006-291X(72)80066-4 · doi:10.1016/s0006-291x(72)80066-4
  157. Stevens, 1976, The photoperoxidation of unsaturated organic molecules XV, Oxygen (O21 delta g) quenching by bilirubin and biliverdin. Photochem Photobiol, 23, 33
  158. Robertson, 1982, A reaction of the superoxide radical with tetrapyrroles, Arch Biochem Biophys, 213, 353, 10.1016/0003-9861(82)90560-4 · DOI
  159. Brodersen, 1969, Enzymatic oxidation of bilirubin, Eur J Biochem, 10, 468, 10.1111/j.1432-1033.1969.tb00712.x · doi:10.1111/j.1432-1033.1969.tb00712.x
  160. Bliuger, 1985, Role of bilirubin as a natural antioxidant in regulation of the intensity of lipid peroxidation in acute virus hepatitis, Biull Exp Biol Med, 99, 193, 10.1007/BF00798666 · doi:10.1007/bf00798666
  161. Stocker, 1987, Antioxidant activity of albumin‐bound bilirubin, Proc Natl Acad Sci USA, 84, 5918, 10.1073/pnas.84.16.5918 · DOI · Paper page
  162. Stocker, 1990, Antioxidant activities of bile pigments: Biliverdin and bilirubin, Methods Enzymol, 186, 301, 10.1016/0076-6879(90)86123-D · DOI · Paper page
  163. Stocker, 1989, Antioxidant properties of conjugated bilirubin and biliverdin: Biologically relevant scavenging of hypochlorous acid, Free Radic Res Commun, 6, 57, 10.3109/10715768909073428 · DOI
  164. Stocker, 1989, Synergistic interaction between vitamin E and the bile pigments bilirubin and biliverdin, Biochim Biophys Acta, 1002, 238, 10.1016/0005-2760(89)90293-2 · DOI
  165. Hulea, 1995, Inhibition of metal catalyzed oxidation of low‐density lipoprotein by free and albumin bound bilirubin, Biochim Biophys Acta, 1259, 29, 10.1016/0005-2760(95)00125-V · DOI
  166. Wu, 1994, Unconjugated bilirubin inhibits the oxidation of human low density lipoprotein better than Trolox, Life Sci, 54, 477, 10.1016/0024-3205(94)90140-6 · doi:10.1016/0024-3205(94)90140-6
  167. Neuzil, 1993, Bilirubin attenuates radical‐mediated damage to serum albumin, FEBS Lett, 331, 281, 10.1016/0014-5793(93)80353-V · DOI · Paper page
  168. Farrera, 1994, The antioxidant role of bile pigments evaluated by chemical tests, Bioorg Med Chem, 2, 181, 10.1016/S0968-0896(00)82013-1 · DOI
  169. Wu, 1991, Albumin‐bound bilirubins protect human ventricular myocytes against oxyradical damage, Biochem Cell Biol, 69, 683, 10.1139/o91-102 · DOI
  170. Wu, 1991, The cytoprotective effects of bilirubin and biliverdin on rat hepatocytes and human erythrocytes and the impact of albumin, Biochem Cell Biol, 69, 828, 10.1139/o91-123 · doi:10.1139/o91-123
  171. Kwak, 1991, Bilirubin inhibits the activation of superoxide‐producing NADPH oxidase in a neutrophil cell‐free system, Biochim Biophys Acta, 1076, 369, 10.1016/0167-4838(91)90478-I · DOI · Paper page
  172. Clark, 2000, Dynamics of haem oxygenase‐1 expression and bilirubin production in cellular protection against oxidative stress, Biochem J, 348, 615, 10.1042/bj3480615 · doi:10.1042/bj3480615 · Paper page
  173. Clark, 2000, Heme oxygenase‐1‐derived bilirubin ameliorates postischemic myocardial dysfunction, Am J Physiol Heart Circ Physiol, 278, H643, 10.1152/ajpheart.2000.278.2.H643 · DOI · Paper page
  174. Wang, 2002, Bilirubin ameliorates bleomycin‐induced pulmonary fibrosis in rats, Am J Respir Crit Care Med, 165, 406, 10.1164/ajrccm.165.3.2003149 · DOI
  175. Hammerman, 2002, Protective effect of bilirubin in ischemia‐reperfusion injury in the rat intestine, J Pediatr Gastroenterol Nutr, 35, 344
  176. Dore, 1999, Bilirubin, formed by activation of heme oxygenase‐2 protects neurons against oxidative stress injury, Proc Natl Acad Sci USA, 96, 2445, 10.1073/pnas.96.5.2445 · DOI · Paper page
  177. Arriaga, 1999, Inhibitory effect of bilirubin on complement‐mediated hemolysis, Biochim Biophys Acta, 1473, 329, 10.1016/S0304-4165(99)00201-9 · DOI
  178. Arraiga, 2002, In vivo anti‐complement effect of bilirubin‐IXalpha, Biochem Pharmacol, 64, 741, 10.1016/S0006-2952(02)01215-7 · doi:10.1016/s0006-2952(02)01215-7
  179. Tögl‐Leimuller, 1986, Albumin as a one way transport vehicle into sites of inflammation, Exp Pathol, 30, 91, 10.1016/S0232-1513(86)80066-4 · doi:10.1016/s0232-1513(86)80066-4
  180. Wang, 2004, Bilirubin inhibits iNOS expression and NO production in response to endotoxin in rats, Hepatology, 40, 424, 10.1002/hep.20334 · DOI · Paper page
  181. Hayashi, 1999, Induction of heme oxygenase‐1 suppresses venular leukocyte adhesion elicited by oxidative stress: Role of bilirubin generated by the enzyme, Circ Res, 85, 663, 10.1161/01.RES.85.8.663 · DOI · Paper page
  182. Keshavan, 2005, Unconjugated bilirubin inhibits VCAM‐1‐mediated transendothelial leukocyte migration, J Immunol, 174, 3709, 10.4049/jimmunol.174.6.3709 · DOI · Paper page
  183. Olinescu, 1999, The levels of bilirubin may be related to an inflammatory condition in patients with coronary heart disease, Rom J Intern Med, 37, 239
  184. Kawamura, 2005, Bilirubin from heme oxygenase‐1 attenuates vascular endothelial activation and dysfunction, Arterioscler Thromb Vasc Biol, 25, 155, 10.1161/01.ATV.0000148405.18071.6a · DOI · Paper page
  185. Soares, 2004, Heme oxygenase‐1 modulates the expression of adhesion molecules associated with endothelial cell activation, J Immunol, 172, 3553, 10.4049/jimmunol.172.6.3553 · DOI · Paper page
  186. Jones, 1995, Adhesion molecules in inflammatory bowel disease, Gut, 36, 724, 10.1136/gut.36.5.724 · DOI · Paper page
  187. Ciprandi, 2002, VCAM‐1 in conjunctival inflammation, Allergy, 57, 961, 10.1034/j.1398-9995.2002.23832_6.x · doi:10.1034/j.1398-9995.2002.23832_6.x
  188. Mrowka, 1999, VCAM‐1, ICAM‐1, and E‐selectin in IgA nephropathy and Schonlein‐Henoch syndrome: Differences between tissue expression and serum concentration, Nephron, 81, 256, 10.1159/000045290 · doi:10.1159/000045290
  189. Carter, 2001, Vascular cell adhesion molecule 1 (CD106): A multifaceted regulator of joint inflammation, Arthritis Rheum, 44, 985, 10.1002/1529-0131(200105)44:5<985::AID-ANR176>3.0.CO;2-P · DOI
  190. Mrowka, 1995, Detection of circulating adhesion molecules ICAM‐1, VCAM‐1 and E‐selectin in Wegener's granulomatosis, systemic lupus erythematosus and chronic renal failure, Clin Nephrol, 43, 288
  191. Mrowka, 1994, Circulating adhesion molecules ICAM‐1, VCAM‐1 and E‐selectin in systemic vasculitis: Marked differences between Wegener's granulomatosis and systemic lupus erythematosus, Clin Investig, 72, 762, 10.1007/BF00180543 · doi:10.1007/bf00180543
  192. Velikova, 1997, Circulating soluble adhesion molecules E‐cadherin, E‐selectin, intercellular adhesion molecule‐1 (ICAM‐1) and vascular cell adhesion molecule‐1 (VCAM‐1) in patients with gastric cancer, Br J Cancer, 76, 1398, 10.1038/bjc.1997.569 · doi:10.1038/bjc.1997.569
  193. Velikova, 1998, Serum concentrations of soluble adhesion molecules in patients with colorectal cancer, Br J Cancer, 77, 1857, 10.1038/bjc.1998.309 · DOI
  194. Vachharajani, 2000, Heme oxygenase modulates selectin expression in different regional vascular beds, Am J Physiol Heart Circ Physiol, 278, H1613, 10.1152/ajpheart.2000.278.5.H1613 · DOI
  195. Nakao, 2004, Biliverdin protects the functional integrity of a transplanted syngeneic small bowel, Gastroenterology, 127, 595, 10.1053/j.gastro.2004.05.059 · DOI · Paper page
  196. Mori, 1991, In vitro anti‐human immunodeficiency virus type 1 activity of biliverdin, a bile pigment, Jpn J Cancer Res, 82, 755, 10.1111/j.1349-7006.1991.tb02698.x · doi:10.1111/j.1349-7006.1991.tb02698.x
  197. Nakagami, 1992, Antiviral activity of a bile pigment, biliverdin, against human herpesvirus 6 (HHV‐6) in vitro, Microbiol Immunol, 36, 381, 10.1111/j.1348-0421.1992.tb02037.x · doi:10.1111/j.1348-0421.1992.tb02037.x
  198. Wang, 2006, Bilirubin can induce tolerance to islets allografts, Endocrinology, 147, 762, 10.1210/en.2005-0632 · DOI
  199. Ribeiro, 2003, Heme oxygenase‐1 fused to a TAT peptide transduces and protects pancreatic beta‐cells, Biochem Biophys Res Commun, 305, 876, 10.1016/S0006-291X(03)00856-8 · DOI
  200. Schwertner, 2004, Low serum bilirubin concentrations and risk of rheumatoid arthritis and lupus nephropathy (abstract), Clin Chem, 50, A53

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Metadata

Venue
Advances in Clinical Chemistry
Publisher
Elsevier
Published
2007
Volume
43
Pages
1-57
ISSN
0065-2423 (ISSN-L)
OpenAlex
W1504634754
Cited by
209
References
6
FWCI
17.41
Type
book chapter
Language
en
Open access
closed
Licence
  • www.elsevier.com/tdm/userlicense/1.0/ (tdm)
  • www.elsevier.com/legal/tdmrep-license (tdm)

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The Heme Catabolic Pathway and its Protective Effects on Oxidative Stress‐Mediated Diseases. (2007). Advances in Clinical Chemistry. https://doi.org/10.1016/s0065-2423(06)43001-8

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