Cited by 166Reproductive tract infections researchPreterm Birth and ChorioamnionitisNeonatal and Maternal Infections

Sexually transmitted diseases and adverse outcomes of pregnancy

Goldenberg, Robert L., Andrews, William W., Yuan, Amy C., MacKay, H. Trent, Louis, Michael E. St.·1997·Clinics in Perinatology

Abstract

We emphasize again that the prevalence of maternal infections may vary in different populations, and others might arrive at different estimates about the percentage of infants colonized and, concerning those infants colonized, about the percentage with adverse outcomes. Additionally, many women are colonized or infected simultaneously with several of the organisms discussed in this review, and this may result in different projections of morbidity and mortality rates than those presented here. We realize also that new information is generated continually describing the relationship between various maternal colonizations and preterm birth, and that screening and treatment protocols for several diseases may reduce the prevalence of adverse outcomes reported here. Therefore, we emphasize that the prevalences of various adverse pregnancy outcomes, as presented in this article, are only approximations and may change as new information becomes available. Nevertheless, we believe it is reasonable to estimate the relative effect of various maternal sexually transmitted diseases on adverse pregnancy outcome as we have done in this article. By comparing the effect of direct transmission of sexually transmitted organisms on adverse outcomes with the effect on overall outcome through an increase in the rate of preterm births, we should be able to use this type of analysis to establish some basis for allocation of resources to future research as well as intervention programs aimed at reducing sexually transmitted disease-related adverse outcomes of pregnancy. Finally, the appreciation of the effect of bacterial vaginosis on outcomes of pregnancy associated with preterm birth gives bacterial vaginosis a greater public health importance than has been attributed to it in the past as the subject of sexually transmitted disease research and prevention.

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Crossref · 10.1016/s0095-5108(18)30182-9

Cites

122 of 122 references verified0 citation errors · 0 not checkable

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  • Vaginal group B streptococcus, U urealyticum, and M hominus colonisations are not associated with increased risk of preterm birth.

    “Vaginal group B streptococcus, U urealyticum, and M hominus colonisations are not associated with increased risk of preterm birth.103, 104”

    From Epidemiology and causes of preterm birth (2008) · cites this paper as [104]

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Authors
Goldenberg, R. L., Andrews, W. W., Yuan, A. C., MacKay, H. T., & Louis, M. E. S.
Affiliations
  • University of Alabama at Birmingham (US)
  • Centers for Disease Control and Prevention (US)
Corresponding author
Goldenberg, Robert L.
Venue
Clinics in Perinatology
Publisher
Elsevier BV
Published
1997-03
Volume
24
Issue
1
Pages
23-41
ISSN
0095-5108 (ISSN-L)
OpenAlex
W1567981394
Cited by
166
References
127
Citations by year
2026: 1 · 2024: 3 · 2023: 4 · 2021: 3 · 2019: 2 · 2018: 1 · 2017: 3 · 2016: 3 · 2015: 3 · 2014: 8 · 2013: 2 · 2012: 5
FWCI
6.33
Type
journal article
Language
en
Open access
closed
Locations
  • Clinics in Perinatology (publishedVersion)
  • PubMed (publishedVersion)
Funders
U.S. Public Health Service (290-92-0055)
Topics
  • Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
  • Health Sciences › Medicine › Epidemiology › Preterm Birth and Chorioamnionitis
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Neonatal and Maternal Infections
Keywords
sexually transmitted infections, adverse pregnancy outcomes, preterm birth, maternal infection, bacterial vaginosis, vertical transmission, neonatal colonization, screening and treatment, resource allocation
MeSH terms
Female, Humans, Infant, Newborn, Obstetric Labor, Premature, Mass Screening, Pregnancy, Pregnancy Complications, Infectious, Pregnancy Outcome, Sexually Transmitted Diseases, Prevalence, Vaginosis, Bacterial, Infectious Disease Transmission, Vertical

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