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Suicide and suicidal behaviour
Open accessAbstract
Suicide is a complex public health problem of global importance. Suicidal behaviour differs between sexes, age groups, geographic regions, and sociopolitical settings, and variably associates with different risk factors, suggesting aetiological heterogeneity. Although there is no effective algorithm to predict suicide in clinical practice, improved recognition and understanding of clinical, psychological, sociological, and biological factors might help the detection of high-risk individuals and assist in treatment selection. Psychotherapeutic, pharmacological, or neuromodulatory treatments of mental disorders can often prevent suicidal behaviour; additionally, regular follow-up of people who attempt suicide by mental health services is key to prevent future suicidal behaviour.
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“some clinical factors that may influence the transition from suicidal ideation to suicide attempt include anxiety disorders, impulse-control disorders, post-traumatic stress disorder, eating disorders, previous self-harm, exposure to suicidal behaviour in others, and alcohol and drug abuse or dependence 6,7,88 .”
From Suicide and suicide risk (2019) · cites this paper as [6]
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“Critically, distal factors appear to be indirectly linked to suicide risk via intermediate phenotypes, like personality traits, negative affect, impulsive-aggression, or cognitive deficits (Turecki et al., 2014, 2016, 2019).”
From Toward objective characterizations of suicide risk: A narrative review of laboratory-based cognitive and behavioral tasks (2023) · cites this paper as Turecki et al., 2016
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“its relationship with suicidal behaviour is evident [2,62]”
From The integrated motivational–volitional model of suicidal behaviour (2018) · cites this paper as [2]
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“One such example is the biopsychosocial model for suicide (Figure 4) 6,29,30 , which describes the interactions of genetic, experiential, psychological, clinical, sociological and environmental factors in the development of suicide risk.”
From Suicide and suicide risk (2019) · cites this paper as [6]
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“In fact, they define the criterion exclusively in terms of treatment options for the underlying psychiatric condition.(12, 33)”
From Psychiatric euthanasia, suicide and the role of gender (2022) · cites this paper as [12]
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“Currently, guidelines are silent on whether suicidal ideation and behavior should play a role in how “irremediability” is defined, potentially exacerbating the risk for error.”
From Psychiatric euthanasia, suicide and the role of gender (2022) · cites this paper as [12]
Experimental — accuracy not yet measuredIn the citing paper
“These age ranges coincide with increased prevalence of suicidal behaviour (though not suicide death) in younger and older adults compared to other age groups”
From Loneliness as a predictor of suicidal ideation and behaviour: a systematic review and meta-analysis of prospective studies (2020) · cites this paper as Turecki and Brent, 2016
In the citing paper
“Despite the apparent heritability of suicidal behavior, risk genes have not been identified.39”
From Suicide (2020) · cites this paper as [39]
In the citing paper
“Twin studies have yielded estimates of the genetic contribution to the risk of suicidal behavior that range from 30 to 50%.39”
From Suicide (2020) · cites this paper as [39]
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Citations
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Structural brain abnormalities in patients with type I bipolar disorder and suicidal behavior
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Metadata
- Authors
- Turecki, G., & Brent, D. A.
- Affiliations
- Douglas Mental Health University Institute (CA)
- Corresponding author
- Turecki, Gustavo
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2016-03
- Volume
- 387
- Issue
- 10024
- Pages
- 1227-1239
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- PMC
- PMC5319859
- OpenAlex
- W1721687418
- Cited by
- 2,338
- References
- 147
- Citations by year
- 2026: 205 · 2025: 222 · 2024: 222 · 2023: 206 · 2022: 341 · 2021: 261 · 2020: 352 · 2019: 167 · 2018: 213 · 2017: 83 · 2016: 45
- FWCI
- 16.75
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Canadian Institute of Health Research (MOP93775, MOP11260, MOP119429, and MOP119430)
- US National Institutes of Health (1R01DA033684)
- US National Institutes of Mental Health (MH056612, MH100451, and MH104311)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- suicide, suicidal behavior, suicide risk factors, suicide prevention, suicide attempts, mental illness, psychotherapy, pharmacotherapy, neuromodulation, high-risk individuals
- MeSH terms
- Suicide Prevention, Brain, Humans, Models, Psychological, Psychotherapy, Risk Factors, Suicide, Case Management, Suicidal Ideation
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