Causal attribution of human papillomavirus genotypes to invasive cervical cancer worldwide: a systematic analysis of the global literature
Abstract
Background Understanding the proportion of invasive cervical cancer (ICC) caused by different human papillomavirus (HPV) genotypes can inform primary (ie, vaccination) and secondary (ie, screening) prevention efforts that target specific HPV genotypes. However, using the global literature to estimate population attributable fractions (AFs) requires a methodological framework to address HPV genotype-specific causality from aggregated data. We aimed to estimate the proportion of ICC caused by different HPV genotypes at the global, regional, and national level. Methods This systematic review identified studies reporting HPV genotype-specific prevalence in ICC or people with normal cervical cytology. We searched PubMed, Embase, Scopus, and Web of Science up to Feb 29, 2024, using the search terms "cervix" and "HPV", with no language restrictions. Odds ratios (ORs) were estimated by comparing HPV genotype-specific prevalence between HPV-positive ICC and normal cervical cytology with logistic regression models, adjusting for region, year of paper publication, and HPV primer or test. HPV genotypes with a lower bound to the 95% CI of the OR greater than 1·0 were judged as causal to ICC. Corresponding regional genotype-specific AFs were calculated as regional HPV prevalence in ICC multiplied by (1 - [1 / OR]) and were proportionally adjusted to total 100%. Global AFs were calculated from regional AFs weighted by number of regional ICC cases in 2022 (GLOBOCAN). Findings The systematic…
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A recent analysis highlighted the need to identify the eight most carcinogenic types in HPV-based screening.
“A recent analysis highlighted the need to identify the eight most carcinogenic types in HPV-based screening.39 53”
Cites
de Sanjose, S., Quint, W. G., Alemany, L., Geraets, D. T., Klaustermeier, J. E., Lloveras, B., Tous, S., Felix, A., Bravo, L. E., Shin, H.-R., et al. (2010) · The Lancet Oncology · doi:10.1016/s1470-2045(10)70230-8 · Cited by 2,728 · see citing works
Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis
de Martel, C., Georges, D., Bray, F., Ferlay, J., & Clifford, G. M. (2020) · The Lancet Global Health · doi:10.1016/s2214-109x(19)30488-7 · Cited by 2,475 · see citing works
Self-citationMuñóz, N., Bosch, F. X., Castellsagué, X., Díaz, M., de Sanjosé, S., Hammouda, D., Shah, K. V., & Meijer, C. J. L. M. (2004) · International Journal of Cancer · doi:10.1002/ijc.20244 · Cited by 1,095 · see citing works
Li, N., Franceschi, S., Howell‐Jones, R., Snijders, P. J. F., & Clifford, G. M. (2010) · International Journal of Cancer · doi:10.1002/ijc.25396 · Cited by 1,067 · see citing works
Self-citationPROPORTION OF DISEASE CAUSED OR PREVENTED BY A GIVEN EXPOSURE, TRAIT OR INTERVENTION1
MIETTINEN, O. S. (1974) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a121617 · Cited by 1,036 · see citing works
Guan, P., Howell‐Jones, R., Li, N., Bruni, L., de Sanjosé, S., Franceschi, S., & Clifford, G. M. (2012) · International Journal of Cancer · doi:10.1002/ijc.27485 · Cited by 927 · see citing works
Self-citationSCHIFFMAN, M. H., Clifford, G. M., & Buonaguro, L. (2009) · Infectious Agents and Cancer · doi:10.1186/1750-9378-4-8 · Cited by 451 · see citing works
Self-citationOne virus, one lesion—individual components of CIN lesions contain a specific HPV type
Quint, W. G. V., Jenkins, D., Molijn, A. C., Struijk, L., van de Sandt, M. M., Doorbar, J., Mols, J., HOOF, C. V., Hardt, K., Struyf, F., et al. (2011) · The Journal of Pathology · doi:10.1002/path.3970 · Cited by 196 · see citing works
Clifford, G. M., Tully, S., & Franceschi, S. (2017) · Clinical Infectious Diseases · doi:10.1093/cid/cix135 · Cited by 196 · see citing works
Self-citationWentzensen, N., SCHIFFMAN, M. H., Dunn, T., Zuna, R. E., Gold, M. A., Allen, R. A., Zhang, R., Sherman, M. E., Wacholder, S., Walker, J. L., et al. (2009) · International Journal of Cancer · doi:10.1002/ijc.24528 · Cited by 186 · see citing works
Human papillomavirus in a necessary cause of invasive cervical cancer worldwide
(1999) · Pure Amsterdam UMC · doi:10.1002/(sici)1096-9896(199909)189:1 · Cited by 140 · see citing works
Biological activity of probable/possible high‐risk human papillomavirus types in cervical cancer
Halec, G., Schmitt, M., Dondog, B., Sharkhuu, E., Wentzensen, N., Gheit, T., Tommasino, M., Kommoss, F., Bosch, F. X., Franceschi, S., et al. (2012) · International Journal of Cancer · doi:10.1002/ijc.27605 · Cited by 136 · see citing works
Self-citationEffect of HIV Infection on Human Papillomavirus Types Causing Invasive Cervical Cancer in Africa
Clifford, G. M., Vuyst, H. D., Tenet, V., Plummer, M., Tully, S., & Franceschi, S. (2016) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000001113 · Cited by 111 · see citing works
Self-citationHPV infection in women with and without cervical cancer in Conakry, Guinea
Keita, N., Clifford, G. M., Koulibaly, M., Douno, K., Kabba, I. S., Haba, M., Sylla, B. S., van Kemenade, F. J., Snijders, P. J. F., Meijer, C. J. L. M., et al. (2009) · British Journal of Cancer · doi:10.1038/sj.bjc.6605140 · Cited by 100 · see citing works
Self-citationHuman papillomavirus infection in women with and without cervical cancer in Warsaw, Poland
Bardin, A., Vaccarella, S., Clifford, G. M., Lissowska, J., Rekosz, M., Bobkiewicz, P., Kupryjańczyk, J., Krynicki, R., Jońska‐Gmyrek, J., Dańska-Bidzińska, A., et al. (2008) · European Journal of Cancer · doi:10.1016/j.ejca.2007.12.001 · Cited by 98 · see citing works
Self-citationA cohort study of cervical screening using partial HPV typing and cytology triage
SCHIFFMAN, M. H., Hyun, N., Raine‐Bennett, T. R., Katki, H. A., Fetterman, B. J., Gage, J. C., Cheung, L. C., Befano, B., Poitras, N. E., Lorey, T. S., et al. (2016) · International Journal of Cancer · doi:10.1002/ijc.30375 · Cited by 82 · see citing works
Cervical carcinoma in Algiers, Algeria: Human papillomavirus and lifestyle risk factors
Hammouda, D., Muñóz, N., Herrero, R., Arslan, A., Bouhadef, A., Oublil, M., Djedeat, B., Fontanière, B., Snijders, P. J. F., Meijer, C. J. L. M., et al. (2004) · International Journal of Cancer · doi:10.1002/ijc.20600 · Cited by 75 · see citing works
Bonjour, M., Charvat, H., Franco, E. L., Piñeros, M., Clifford, G. M., Bray, F., & Baussano, I. (2021) · The Lancet Public Health · doi:10.1016/s2468-2667(21)00046-3 · Cited by 73 · see citing works
Self-citationKhalil, A. I., Mpunga, T., Wei, F., Baussano, I., de Martel, C., Bray, F., Stelzle, D., Dryden‐Peterson, S., Jaquet, A., Horner, M., et al. (2021) · International Journal of Cancer · doi:10.1002/ijc.33841 · Cited by 71 · see citing works
Self-citationKalantari, M., García-Carrancá, A. M., Morales-Vazquez, C. D., Zuna, R. E., Pérez‐Montiel, D., Calleja-Macias, I. E., Johansson, B., Andersson, S., & Bernard, H. (2009) · Virology · doi:10.1016/j.virol.2009.05.006 · Cited by 58 · see citing works
Human papillomavirus infection in women with and without cervical cancer in Nepal
Sherpa, A. T., Clifford, G. M., Vaccarella, S., Shrestha, S., Nygård, M., Karki, B. M. S., Snijders, P. J. F., Meijer, C. J. L. M., & Franceschi, S. (2009) · Cancer Causes & Control · doi:10.1007/s10552-009-9467-z · Cited by 56 · see citing works
Self-citationThe evolving definition of carcinogenic human papillomavirus
Castle, P. E. (2009) · Infectious Agents and Cancer · doi:10.1186/1750-9378-4-7 · Cited by 43 · see citing works
Mpunga, T., Umulisa, M. C., Tenet, V., Rugwizangoga, B., Milner, D. A., Munyanshongore, C., Heideman, D. A. M., Bleeker, M. C. G., Tommasino, M., Franceschi, S., et al. (2019) · International Journal of Cancer · doi:10.1002/ijc.32491 · Cited by 42 · see citing works
Self-citationImpact of cervical screening by human papillomavirus genotype: Population-based estimations
Wang, J., Elfström, K. M., Lagheden, C., Eklund, C., Sundström, K., Sparén, P., & Dillner, J. (2023) · PLoS Medicine · doi:10.1371/journal.pmed.1004304 · Cited by 36 · see citing works
Inturrisi, F., de Sanjosé, S., Desai, K. T., Dagnall, C. L., Egemen, D., Befano, B., Rodríguez, A. C., Jerónimo, J., Zuna, R. E., Hoffman, A., et al. (2023) · International Journal of Cancer · doi:10.1002/ijc.34698 · Cited by 33 · see citing works
Mix, J. M., Saraiya, M., Hallowell, B. D., Befano, B., Cheung, L. C., Unger, E. R., Gargano, J. W., Markowitz, L. E., Castle, P. E., Raine‐Bennett, T. R., et al. (2022) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djac034 · Cited by 30 · see citing works
Palmer, M., Katanoda, K., Saito, E., Martellucci, C. A., Tanaka, S., Ikeda, S., Sakamoto, H., Machelek, D., Brotherton, J. M. L., & Hocking, J. S. (2022) · Vaccine · doi:10.1016/j.vaccine.2022.07.052 · Cited by 13 · see citing works
Laser Capture Microdissection and PCR for Analysis of Human Papilloma Virus Infection
Chew, K., Rooney, P. H., Cruickshank, M. E., & Murray, G. I. (2005) · Humana Press eBooks · doi:10.1385/1-59259-853-6:295 · Cited by 8 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Roles of human papillomavirus in cancers: oncogenic mechanisms and clinical use
Zhang, Y., Qiu, K., Ren, J., Zhao, Y. Q., & Cheng, P. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-02083-w · Cited by 125 · see citing works
Global HPV vaccination programs and coverage rates: a systematic review
Jingjing, H., Zhang, L., Chen, Y., Zhang, Y., Wang, L., Cai, R., Li, M., Dai, Y., Dang, L., Chen, H., et al. (2025) · EClinicalMedicine · doi:10.1016/j.eclinm.2025.103290 · Cited by 118 · see citing works
Human papilloma virus (HPV) mediated cancers: an insightful update
Baba, S. K., Alblooshi, S. S. E., Yaqoob, R., Behl, S., Saleem, M. A., Rakha, E. A., Malik, F. A., Singh, M. K., Macha, M. A., Akhtar, K., et al. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06470-x · Cited by 90 · see citing works
Massad, L. S., Clarke, M. A., Perkins, R. B., García, F., Chelmow, D. P., Cheung, L. C., Darragh, T. M., Egemen, D., Lorey, T. S., Nayar, R., et al. (2025) · Journal of Lower Genital Tract Disease · doi:10.1097/lgt.0000000000000865 · Cited by 71 · see citing works
Wang, J., Elfström, K. M., & Dillner, J. (2024) · The Lancet Public Health · doi:10.1016/s2468-2667(24)00218-4 · Cited by 63 · see citing works
Cancer of the cervix uteri: 2025 update
Bhatla, N., Aoki, D., Sharma, D. N., & Sankaranarayanan, R. (2025) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.70277 · Cited by 58 · see citing works
Noninferiority of One HPV Vaccine Dose to Two Doses
Kreimer, A. R., Porras, C., Liu, D., Hildesheim, A., Carvajal, L. J., Ocampo, R., Romero, B., Gail, M. H., Cortés, B., Sierra, M. S., et al. (2025) · New England Journal of Medicine · doi:10.1056/nejmoa2506765 · Cited by 54 · see citing works
Advances and prospects of precision nanomedicine in personalized tumor theranostics
Mao, Y., Xie, J., Yang, F., Luo, Y., Du, J., & Xiang, H. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1514399 · Cited by 36 · see citing works
Population-Based Age-Period-Cohort Analysis of Declining Human Papillomavirus Prevalence
Gray, P. G., Wang, J., Kleppe, S. N., Elfström, M. K., & Dillner, J. (2025) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaf032 · Cited by 32 · see citing works
Malvi, S. G., Esmy, P. O., Muwonge, R., Joshi, S., Poli, U. R., Lucas, E., Verma, Y., Lucksom, P. G., Shah, A., Patel, B. M., et al. (2024) · JNCI Monographs · doi:10.1093/jncimonographs/lgae042 · Cited by 30 · see citing works
Son, Y., Hong, S., Jang, W., Kim, S., Lee, H., Lee, S., Kang, J., Smith, L., & Yon, D. K. (2025) · International Journal of Gynecological Cancer · doi:10.1016/j.ijgc.2025.102751 · Cited by 28 · see citing works
El‐Zein, M., & Franco, E. L. (2025) · Expert Review of Molecular Diagnostics · doi:10.1080/14737159.2025.2486653 · Cited by 19 · see citing works
Dong, B., Lü, Z., Yang, T., Wang, J., Zhang, Y., Tuo, X., Wang, J., Lin, S., Cai, H., Huan, C., et al. (2025) · The Lancet Regional Health - Western Pacific · doi:10.1016/j.lanwpc.2025.101480 · Cited by 20 · see citing works
Befano, B., Kalpathy–Cramer, J., Egemen, D., Inturrisi, F., Jerónimo, J., Rodríguez, A. C., Campos, N. G., Cremer, M., Ribeiro, A. K. D. C., Ajenifuja, K. O., et al. (2025) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djaf054 · Cited by 17 · see citing works
Hanzala, A., Akter, T., & Rahman, M. S. (2025) · Array · doi:10.1016/j.array.2025.100434 · Cited by 16 · see citing works
Kamzayeva, N., Bapayeva, G., Terzić, M., Primbetov, B., Imankulova, B., Kim, Y., Sultanova, A., Kongrtay, K., Kadroldinova, N., & Ukybassova, T. (2025) · Life · doi:10.3390/life15030367 · Cited by 19 · see citing works
Kayar, İ., Göç, G., Çetin, F., & Birge, Ö. (2025) · Medicina · doi:10.3390/medicina61020235 · Cited by 15 · see citing works
Population-Level Effectiveness and Herd Protection 17 Years After HPV Vaccine Introduction
DeSieghardt, A., Ding, L., Ermel, A. C., Franco, E. L., Dagnall, C. L., Brown, D. R., Yao, S., & Kahn, J. A. (2025) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2025.3568 · Cited by 14 · see citing works
The Epithelial Immune Response to Human Papillomavirus Infection
Roy-Biswas, S., & Hibma, M. H. (2025) · Pathogens · doi:10.3390/pathogens14050464 · Cited by 16 · see citing works
Shao, D., Wu, P., Jiang, H., & Wang, Z. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1702186 · Cited by 13 · see citing works
Cancer burden and control in China: landscape, trends and challenges
Xia, C., Li, H., Chen, W., & Chen, W. (2026) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-026-01165-8 · Cited by 13 · see citing works
Brotherton, J. M. L., Vajdic, C. M., & Nightingale, C. E. (2025) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1080/14737167.2025.2451732 · Cited by 14 · see citing works
Cancer Development and Progression Through a Vicious Cycle of DNA Damage and Inflammation
Kawanishi, S., Wang, G., Ma, N., & Murata, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26073352 · Cited by 12 · see citing works
Global status of HPV vaccination two decades in: effective, safe and preventing cancer
Brotherton, J. M. L., LaMontagne, D. S., & Bloem, P. N. (2025) · Expert Review of Vaccines · doi:10.1080/14760584.2025.2609869 · Cited by 12 · see citing works
Sexually transmitted human papillomavirus and related sequelae
Hanft, W., Karita, H. C. S., Khorsandi, N., Vohra, P., & Plotzker, R. E. (2025) · Clinical Microbiology Reviews · doi:10.1128/cmr.00085-23 · Cited by 15 · see citing works
Ramírez, A. T., Clifford, G. M., Dillner, J., Kuhn, L., Arbyn, M., Bhatla, N., Wentzensen, N., Sasieni, P. D., Abraham, P., Rol, M. L., et al. (2025) · Journal of Medical Virology · doi:10.1002/jmv.70310 · Cited by 10 · see citing works
Self-citationMiddeldorp, M., Brouwer, J. G. M., Duijster, J. W., Knol, M. J., van Kemenade, F. J., Siebers, A. G., Berkhof, J. H., & de Melker, H. E. (2025) · The Lancet Regional Health - Europe · doi:10.1016/j.lanepe.2025.101327 · Cited by 11 · see citing works
Deng, Z., Mao, X., Yang, Y., Wu, G., Meng, H., Hou, J., Yu, X., Zhou, W., Mao, G., & Ma, Y. (2025) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2025.117960 · Cited by 11 · see citing works
Guo, Y., Xiao, Y., Zhang, C., Wang, Y., Cao, G., Tse, K. Y., Han, Z., Li, F., & Zhi, Y. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1574511 · Cited by 11 · see citing works
Tota, J. E., Shing, J. Z., Roberts, J. N., Anderson, E. M., Saah, A. J., Harari, A., Franco, E. L., Kohn, M. A., & Kjær, S. K. (2025) · International Journal of Cancer · doi:10.1002/ijc.70119 · Cited by 10 · see citing works
Pedersen, K., Silvestre, J. D., Sy, S., Portnoy, A., Castle, P. E., Kim, J. J., & Burger, E. A. (2026) · Annals of Internal Medicine · doi:10.7326/annals-25-03192 · Cited by 11 · see citing works
Sekyere, J. O., Trama, J. P., Adelson, M. E., Trikannad, C., DiBlasi, D., Schuster, R., Yang, J., & Mordechai, E. (2025) · iScience · doi:10.1016/j.isci.2025.113473 · Cited by 12 · see citing works
Xie, F., Du, K., Li, J., Zhong, S., Fan, C., Bi, Z., Zhang, Q., Chen, J., Ma, S., & Zhang, D. (2025) · Vaccine · doi:10.1016/j.vaccine.2025.127015 · Cited by 9 · see citing works
HPV Infection in Children and Adolescents—A Comprehensive Review
Tomecka, P., Karwowska, A., Kuźnicki, J., Skinderowicz, K., Wojno, A., Markut, K., Typek, P., Ciesielska, U., Kulbacka, J., & Drąg‐Zalesińska, M. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14072425 · Cited by 8 · see citing works
van den Borst, E., Bell, M., de Beeck, K. O., Camp, G. V., Keer, S. V., & Vorsters, A. (2025) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djaf118 · Cited by 10 · see citing works
Cationic nanogel–based nasal therapeutic HPV vaccine prevents the development of cervical cancer
Nakahashi-Ouchida, R., Mori, H., Yuki, Y., Machita, T., Katakai, Y., Umemoto, S., Uchida, Y., Yamanoue, T., Sawada, S., Ishige, K., et al. (2025) · Science Translational Medicine · doi:10.1126/scitranslmed.ado8840 · Cited by 10 · see citing works
Happel, A., Budiawan, E., Onono, M. A., Innes, S., Palanee‐Phillips, T., Heuvel, J., Rakiep, A., Kellow-Webb, S., Ongere, J. A., Wakhungu, I., et al. (2024) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofae690 · Cited by 7 · see citing works
Adebamowo, C., Rossi, P. G., & Castle, P. E. (2025) · American Society of Clinical Oncology Educational Book · doi:10.1200/edbk-25-473702 · Cited by 12 · see citing works
Human papillomavirus 16 mitigates Sneathia vaginalis -induced damage to cervical keratinocytes
Bridy, P. V., Cruz, J. C., Covington, J. L., Islam, T. I., Hadley, C. E., Tran, K., Fry, R., Sheffield, B. A., Serrano, M. G., Buck, G. A., et al. (2025) · mSphere · doi:10.1128/msphere.00152-25 · Cited by 7 · see citing works
Kęczkowska, E., Wrotyńska-Barczyńska, J., Bałabas, A., Piątkowska, M., Dąbrowska, M., Czarnowski, P., Hennig, E. E., Brązert, M., Olcha, P., Ciebiera, M., et al. (2025) · Biology · doi:10.3390/biology14081081 · Cited by 7 · see citing works
Zhou, X., Ma, J., He, L., & Li, H. (2025) · Infectious Agents and Cancer · doi:10.1186/s13027-025-00698-4 · Cited by 7 · see citing works
Genotype and age shape the risk of persistent high-risk human papillomavirus infections
Numminen, E., Leino, A., Qiang, K., Veronika, F., Seiskari, T., Paloniemi, M., Kholová, I., Kares, S., & Louvanto, K. (2026) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2026.02.038 · Cited by 7 · see citing works
Opportunities to advance cervical cancer prevention and care
Brooke, G., Wendel, S. O., Banerjee, A., & Wallace, N. A. (2024) · Tumour Virus Research · doi:10.1016/j.tvr.2024.200292 · Cited by 7 · see citing works
Man, I., Georges, D., Basu, P. S., & Baussano, I. (2024) · JNCI Monographs · doi:10.1093/jncimonographs/lgae035 · Cited by 7 · see citing works
Self-citationGao, D., Zhao, G., Wang, X., Juan, J., Shi, Y., Xu, T., Wang, Y., Wang, L., & Zhang, X. (2025) · China CDC Weekly · doi:10.46234/ccdcw2025.053 · Cited by 7 · see citing works
Vahteristo, M., Heinävaara, S. H., Dillner, J., Kalliala, I. E. J., Nieminen, P., Sarkeala, T. M., & Leinonen, M. K. (2025) · International Journal of Cancer · doi:10.1002/ijc.70123 · Cited by 6 · see citing works
Machalek, D. A., Nyemba, D. C., Travill, D., Petoumenos, K., Mbulawa, Z. Z. A., Naidoo, I., Motshwane, F. M. M., Bamford, L., Rees, H., Kaldor, J. M., et al. (2026) · The Lancet Global Health · doi:10.1016/s2214-109x(25)00525-x · Cited by 6 · see citing works
do Nascimento, G. R., Santos, A. C. D. S., Silva, N. N. T., Guimarães, N. S., Lima, A. A., & Coura‐Vital, W. (2025) · BMC Infectious Diseases · doi:10.1186/s12879-025-10520-6 · Cited by 6 · see citing works
Bose, S., Mandal, R., Banerjee, D., Vernekar, M., Siddiqi, M., Chakrabarti, J., Sankaranarayanan, R., Lucas, E., Muwonge, R., & Basu, P. S. (2025) · Cancer Epidemiology · doi:10.1016/j.canep.2025.102776 · Cited by 6 · see citing works
Ad‐E6/7‐HR vaccine improves the prophylactic and therapeutic efficacy in HPV‐associated cancers
Zhang, Y., Qiu, K., Ai, J., Xu, M., Wang, B., Alu, A., Ye, C., Huang, X., Zhang, Y. L., Zhou, Y., et al. (2025) · Clinical and Translational Medicine · doi:10.1002/ctm2.70305 · Cited by 6 · see citing works
van den Borst, E., Broeck, D. V., Sutter, P. D., Donders, G. G. G., Doyen, J., Tjalma, W. A. A., Weyers, S., Arbyn, M., Keer, S. V., & Latsuzbaia, A. (2025) · Gynecologic Oncology · doi:10.1016/j.ygyno.2025.08.018 · Cited by 6 · see citing works
Molina-Castillo, G., Monroy-García, A., García‐Rocha, R., Weiss‐Steider, B., Montesinos, J. J., Hernández‐Montes, J., Don‐López, C. A., Castro-Manrreza, M. E., Escobar, M. L., & Mora‐García, M. D. L. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26062413 · Cited by 5 · see citing works
Human papillomavirus (HPV) as the main cause of cervical and other related cancers: a review
Moosa-Battey, R., Masuku, P., & Mayimele, N. N. (2025) · SA pharmaceutical journal. · doi:10.36303/sapj.1164 · Cited by 5 · see citing works
Emerging Therapeutic Strategies for HPV-Related Cancers: From Gene Editing to Precision Oncology
Çakır, M. O., Kayhan, G., Yilmaz, B., Özdoğan, M., & Ashrafi, G. H. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47090759 · Cited by 8 · see citing works
Chen, Q., Wang, S., Lin, Q., & Zhang, G. (2025) · BMC Public Health · doi:10.1186/s12889-025-24323-6 · Cited by 5 · see citing works
A Field‐Deployable RotEx‐LAMP‐LFA Platform for Molecular Triage of HPV‐Driven Oncogenesis
Gao, Y., Wen, Q., Qiao, S., Deng, L., Li, K., Shao, Z., Liu, X., Zhu, T., Zhang, C., Han, D., et al. (2025) · Advanced Science · doi:10.1002/advs.202509468 · Cited by 5 · see citing works
Tahir, M., Mohammed, D., & Sadiq, C. H. (2025) · Virology Journal · doi:10.1186/s12985-025-03021-0 · Cited by 5 · see citing works
Nonboe, M. H., Napolitano, G. M., Schroll, J. B., Andersen, B. S., Christiansen, S., Frandsen, A. P., Pedersen, H., Lynge, E., Bonde, J. H., & Høgdall, E. V. S. (2025) · Vaccine · doi:10.1016/j.vaccine.2025.128142 · Cited by 5 · see citing works
Global burden of cancer attributable to infections in 2024: a worldwide incidence analysis
Rumgay, H., Georges, D., Huang, Y., Hirabayashi, M., Shah, R., de Martel, C., Park, J. Y., Soerjomataram, I., & Clifford, G. M. (2026) · The Lancet Oncology · doi:10.1016/s1470-2045(26)00307-4 · Cited by 5 · see citing works
Self-citationAccuracy of Liferiver HarmoniaHPV and VenusHPV Assays on Urine and Vaginal Self‐Samples
Latsuzbaia, A., Keer, S. V., Broeck, D. V., Weyers, S., Donders, G. G. G., Sutter, P. D., Tjalma, W. A. A., Doyen, J., Vorsters, A., & Arbyn, M. (2025) · Journal of Medical Virology · doi:10.1002/jmv.70273 · Cited by 5 · see citing works
The challenging approach to the management of male partners of HPV-positive women
Bornstein, J., Vieira‐Baptista, P., Stockdale, C. K., Preti, M., Joura, E. A., & Schejter, E. (2025) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2025.2515753 · Cited by 5 · see citing works
Plisko, O., Žodžika, J., Jermakova, I., Pčolkina, K., Prusakevica, A., Liepniece‐Karele, I., Zarina, M., Storoženko, J., & Rezeberga, D. (2024) · PLoS ONE · doi:10.1371/journal.pone.0313004 · Cited by 4 · see citing works
Dema, E., Shing, J. Z., Checchi, M., Beddows, S. A., Liu, D., Sierra, M. S., Haas, C. B., Soldan, K., Field, N. M., Kreimer, A. R., et al. (2025) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-24-1775 · Cited by 4 · see citing works
Kacperczyk-Bartnik, J. P., Hajj, H. E., Tóth, I., Bizzarri, N., Tóth, R., Razumova, Z., Zwimpfer, T. A., Taumberger, N., Bilir, E., Strojna, A. N., et al. (2025) · International Journal of Gynecological Cancer · doi:10.1016/j.ijgc.2025.101902 · Cited by 4 · see citing works
Palena, G., Stilo, I., Sorrentino, M., Fiorilla, C., & Palladino, R. (2025) · PLoS ONE · doi:10.1371/journal.pone.0326694 · Cited by 4 · see citing works
Jing, Y., Chen, J., Lin, F., Huang, X., Liu, Y., Zhao, M., Ye, C., Zhao, L., Liu, X., & Yang, J. (2025) · Virology Journal · doi:10.1186/s12985-025-02904-6 · Cited by 4 · see citing works
Mboumba-Mboumba, M., Mouinga‐Ondémé, A., Moussavou-Boundzanga, P., Engone-Ondo, J. D., Mourimarodi, R. M., Diane, A., Ayoumi, C. O., Bélec, L., Bouassa, R. M., & Mfouo-Tynga, I. S. (2025) · Diseases · doi:10.3390/diseases13080260 · Cited by 4 · see citing works
Chen, Z., Lin, E., Chen, M., Wang, S., Lin, Q., Chen, Q., Xue, H., & Zhang, G. (2025) · JMIR Public Health and Surveillance · doi:10.2196/70507 · Cited by 4 · see citing works
Waheed, D.-E.-N., Bolio, A., Burdier, F. R., Guillaume, D., Biey, J., Ndiaye, C., Karafillakis, E., Kouassi, K. S., Vorsters, A., & Morgan, C. (2025) · Vaccine · doi:10.1016/j.vaccine.2025.128030 · Cited by 4 · see citing works
Exceeding expectations: factors contributing to the potency of human papillomavirus vaccines
Schiller, J. T., Kines, R. C., Day, P. M., Çuburu, N., Kreimer, A. R., & Lowy, D. R. (2026) · The Lancet Microbe · doi:10.1016/j.lanmic.2026.101401 · Cited by 4 · see citing works
The rational design of cervical cancer prevention strategies
Schiffman, M., & de Sanjose, S. (2024) · The Lancet · doi:10.1016/s0140-6736(24)01547-2 · Cited by 4 · see citing works
Edvardsson, H., & Dillner, J. (2025) · Acta Cytologica · doi:10.1159/000544988 · Cited by 4 · see citing works
Zhong, G., Bi, Z., Chu, K., Zhang, L., Chen, L., Zhu, K., Quan, J., Nie, C., Chen, Q., Qiu, L., et al. (2025) · The Lancet Regional Health - Western Pacific · doi:10.1016/j.lanwpc.2025.101671 · Cited by 4 · see citing works
Ye, C., Liu, Y., Huang, H., Chen, R., Li, Y., Zhang, X., Fu, Y., Feng, L., & Li, X. (2025) · Journal of Medical Virology · doi:10.1002/jmv.70404 · Cited by 3 · see citing works
Yu, J., Ju, Y., Kim, D., Qian, A., Du, B., Liu, N., & Wei, Z. (2025) · Journal of Medical Virology · doi:10.1002/jmv.70424 · Cited by 3 · see citing works
Chen, M., Lhamo, Y., Chödrön, K., & Chen, L. (2025) · Virology Journal · doi:10.1186/s12985-025-02909-1 · Cited by 3 · see citing works
HPV Integration: Moving From Carcinogenesis Mechanisms to Clinical Applications
Lai, S., Liu, H., Chu, T., & Cao, C. (2025) · Med Research · doi:10.1002/mdr2.70026 · Cited by 3 · see citing works
Yordanov, A. D., Damyanova, P., Vasileva‐Slaveva, M., Karakadieva, K., Kostov, S. G., & Shivarov, V. S. (2025) · Biomedicines · doi:10.3390/biomedicines13092206 · Cited by 3 · see citing works
Solis-Ponce, L., Stosic, M. S., Curicó, G., Espetia, S., Sanchez-Grandez, H., Hassan, S. S., Basiletti, J. A., Søreng, K., Acuña, M., Huarca, L., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-18455-3 · Cited by 3 · see citing works
The role of extrachromosomal DNA in tumorigenesis and progression
Ma, X., Yu, X., Wu, C., & Song, L. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1665024 · Cited by 3 · see citing works
Zhang, Y., Ma, S., & He, Z. (2025) · BMC Infectious Diseases · doi:10.1186/s12879-025-11590-2 · Cited by 3 · see citing works
Aliabadi, N., Hosseini, M., Doustfatemeh, S., Marandi, N. H., Joukar, M., Faramarzi, H., Asmarian, N., & Namazi, N. (2025) · Health Science Reports · doi:10.1002/hsr2.71624 · Cited by 3 · see citing works
Mabika-Obanda, A. K. F., Ledaga, N. A., Ngou-Milama, K. M. M., Obame, V. Z., Emane, A. K. A., Sanon, A., Ndong-Ella, C., Loemba, H., Bélec, L., Ngou, J. P. N. M., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-67777-3 · Cited by 3 · see citing works
Sardinha, T. G., Vale, D. B., Discacciati, M. G., Triglia, R. D. M., Coelho, R. M. R. D. S., Jundurian, M., Campos, C. S., Zeferino, L. C., & Teixeira, J. C. (2025) · International Journal of Gynecological Cancer · doi:10.1016/j.ijgc.2025.104451 · Cited by 3 · see citing works
Kumar, S., Yadav, P., Maurya, A., Yadav, S. C., & Prasad, T. (2026) · ChemistrySelect · doi:10.1002/slct.202505590 · Cited by 3 · see citing works
Quan, J., Chen, Q., Lan, L., Zhang, B., Hu, Y., Zhao, F., Wang, X., Wang, X., Huang, J., Zhong, G., et al. (2026) · International Journal of Cancer · doi:10.1002/ijc.70337 · Cited by 3 · see citing works
Morel, D. R., Parvu, V., Andrews, J., Stephenson, P., Bull, J., Woodward, A., & Vaughan, L. M. (2026) · Gynecologic Oncology · doi:10.1016/j.ygyno.2026.02.016 · Cited by 3 · see citing works
Li, X., Sun, Y., Lun, X., Liang, Y., Jin, R., & Liu, J. (2026) · Journal of Infection · doi:10.1016/j.jinf.2026.106732 · Cited by 3 · see citing works
Kapp, P., Siemens, W., Gorenflo, L., Schulz, H., Chi, Y., Röbl-Mathieu, M., Askar, M., Brotons, M., Andersen, P. H., Konopnicki, D., et al. (2026) · EClinicalMedicine · doi:10.1016/j.eclinm.2026.103865 · Cited by 3 · see citing works
Oncogenic infections: targets highly amenable to cancer prevention
Alberts, C. J., Georges, D., Franceschi, S., Baussano, I., Park, J. Y., Rumgay, H., Basu, P. S., & Clifford, G. M. (2025) · JNCI Monographs · doi:10.1093/jncimonographs/lgaf040 · Cited by 3 · see citing works
Self-citationGenotypic analysis of human papillomavirus in cervical exfoliated cells from women in Zigong
Ma, X., Wu, C., Wu, T., Yu, X., & Song, L. (2025) · Virology Journal · doi:10.1186/s12985-025-02652-7 · Cited by 3 · see citing works
Chen, Z., Cheng, Q., Zhang, X., Tao, F., Li, N., Liu, G., Mu, X., Zhang, M., Dong, Z., & Li, Q. (2025) · Virology Journal · doi:10.1186/s12985-025-02688-9 · Cited by 3 · see citing works
Li, Q., Cheng, Q., Tian, D., An, Z., Li, L., Yang, F., Zhang, M., Liu, G., Peixin, A., Yang, Y. F., et al. (2025) · Virology Journal · doi:10.1186/s12985-025-02752-4 · Cited by 3 · see citing works
Xu, J., Ji, Q., Kong, Q., Lv, L., Bo, Z., Huang, X., Chen, Z., Xu, P., Li, X., Yin, W., et al. (2025) · Cell Reports Medicine · doi:10.1016/j.xcrm.2025.102149 · Cited by 3 · see citing works
Sustova, P., Engesæter, B. Ø., Øvestad, I. T., Gudlaugsson, E. G., Ghiasvand, R., Skaland, I., Baak, J. P. A., Tropé, A., Janssen, E. A. M., & Munk, A. C. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26115205 · Cited by 3 · see citing works
Ngân, L. T. K., Ba, H. V., Kim, D. H. T., Khoa, D. T. D., Hùng, N. T., Tram, P. T. B., Trang, N. T. T., Khiêm, N. H., Thảo, P. T., Hien, T. D., et al. (2025) · Infectious Agents and Cancer · doi:10.1186/s13027-025-00685-9 · Cited by 3 · see citing works
China adds HPV shot as first new immunisation programme vaccine in 17 years
Murphy, F. (2025) · BMJ · doi:10.1136/bmj.r1985 · Cited by 3 · see citing works
Arévalos, A., Valenzuela, A., Mongelós, P., Barrios, H., Rodríguez-Riveros, M. I., Báez, R., Centurión, C., Vester, J. M., Soilán, A. M., Ortega, M., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0312947 · Cited by 3 · see citing works
Chen, Z., Li, X., Tian, D., Liu, J. J., Bai, X., Feng, T., Chen, S., Chen, L., & Li, Q. (2024) · Virology Journal · doi:10.1186/s12985-024-02582-w · Cited by 3 · see citing works
Discontinuation of cervical cancer screening for HPV ‐vaccinated women?
Bonde, J. H., & Hammer, A. (2024) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.14978 · Cited by 3 · see citing works
- Authors
- Wei, F., Georges, D., Man, I., Baussano, I., & Clifford, G. M.
- Affiliations
- Centre international de recherche sur le cancer (FR)
- Corresponding author
- Clifford, Gary M
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2024-08
- Volume
- 404
- Issue
- 10451
- Pages
- 435-444
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W4401206220
- Cited by
- 317
- References
- 28
- Citations by year
- 2026: 158 · 2025: 144 · 2024: 15
- FWCI
- 96.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Funders
- European Union
- Topics
- Health Sciences › Medicine › Epidemiology › Cervical Cancer and HPV Research
- Health Sciences › Medicine › Otorhinolaryngology › Head and Neck Cancer Studies
- Health Sciences › Medicine › Surgery › Genital Health and Disease
- Keywords
- human papillomavirus, HPV genotypes, invasive cervical cancer, population attributable fraction, causal attribution, HPV16, HPV 18, HPV45, HPV 33, HPV58, HPV 31, HPV52, HPV51, HPV35, HPV 59, HPV39, HPV 56, HPV73
- MeSH terms
- Human Papillomavirus Viruses, Uterine Cervical Neoplasms, Female, Genotype, Humans, Global Health, Prevalence, Papillomaviridae, Papillomavirus Infections
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