ISLET-CELL ANTIBODIES IN DIABETES MELLITUS WITH AUTOIMMUNE POLYENDOCRINE DEFICIENCIES
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Franco Bottazzo was the first to successfully visualize islet cell antibodies using indirect immunofluorescence, confirming the presence of antibodies reactive to the islet.
“In a now famous ‘eureka’ moment, in 1974, Franco Bottazzo, a research fellow in Deborah Doniach’s laboratory in London, was the first to successfully visualize islet cell antibodies using indirect immunofluorescence, thereby confirming the presence of antibodies reactive to the islet.”
From 100 years of insulin: celebrating the past, present and future of diabetes therapy (2021) · cites this paper as [5]
Cited by
Sorted by citations
Type 1 diabetes: new perspectives on disease pathogenesis and treatment
Atkinson, M. A., & Eisenbarth, G. S. (2001) · The Lancet · doi:10.1016/s0140-6736(01)05415-0 · Cited by 1,491 · see citing works
The Role of Inflammation in Diabetes: Current Concepts and Future Perspectives
Tsalamandris, S., Antonopoulos, A. S., Oikonomou, E., Papamikroulis, G.-A., Vogiatzi, G., Papaioannou, S., Deftereos, S., & Tousoulis, D. (2019) · European Cardiology Review · doi:10.15420/ecr.2018.33.1 · Cited by 1,381 · see citing works
Turner, R., Stratton, I., Horton, V., Manley, S., Zimmet, P., Mackay, I. R., Shattock, M., Bottazzo, G. F., & Holman, R. (1997) · The Lancet · doi:10.1016/s0140-6736(97)03062-6 · Cited by 779 · see citing works
Self-citationFeutren, G., Assan, R., Karsenty, G., Du Rostu, H., Sirmai, J., Papoz, L., Vialettes, B., Vexiau, P., Rodier, M., Lallemand, A., et al. (1986) · The Lancet · doi:10.1016/s0140-6736(86)91943-4 · Cited by 448 · see citing works
100 years of insulin: celebrating the past, present and future of diabetes therapy
Sims, E. K., Carr, A. L. J., Oram, R. A., DiMeglio, L. A., & Evans-Molina, C. (2021) · Nature Medicine · doi:10.1038/s41591-021-01418-2 · Cited by 270 · see citing works
New frontiers in the treatment of type 1 diabetes
Warshauer, J. T., Bluestone, J. A., & Anderson, M. S. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2019.11.017 · Cited by 259 · see citing works
Orban, T., Sosenko, J. M., Cuthbertson, D., Krischer, J. P., Skyler, J. S., Jackson, R., Yu, L., Palmer, J. P., Schatz, D., Eisenbarth, G., et al. (2009) · Diabetes Care · doi:10.2337/dc09-0934 · Cited by 260 · see citing works
Parikka, V., Näntö-Salonen, K., Saarinen, M., Simell, T., Ilonen, J., Hyöty, H., Veijola, R., Knip, M., & Simell, O. (2012) · Diabetologia · doi:10.1007/s00125-012-2523-3 · Cited by 235 · see citing works
T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins
Roep, B. O., Arden, S. D., de vries, R. R. P., & Hutton, J. C. (1990) · Nature · doi:10.1038/345632a0 · Cited by 185 · see citing works
Evidence of islet cell autoimmunity in elderly patients with type 2 diabetes.
Pietropaolo, M., Barinas-Mitchell, E., Pietropaolo, S. L., Kuller, L. H., & Trucco, M. (2000) · Diabetes · doi:10.2337/diabetes.49.1.32 · Cited by 159 · see citing works
Palmer, J. P., Hampe, C. S., Chiu, H., Goel, A., & Brooks-Worrell, B. M. (2005) · Diabetes · doi:10.2337/diabetes.54.suppl_2.s62 · Cited by 136 · see citing works
Islet cell autoantigens in insulin-dependent diabetes
Atkinson, M. A., & Maclaren, N. K. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116745 · Cited by 129 · see citing works
The World Health Organization International Collaborative Study for islet cell antibodies
Mire-Sluis, A. R., Gaines Das, R., & Lernmark, &. (2000) · Diabetologia · doi:10.1007/s001250051524 · Cited by 122 · see citing works
Jones, A. G., McDonald, T. J., Shields, B. M., Hagopian, W., & Hattersley, A. T. (2021) · Diabetes Care · doi:10.2337/dc20-2834 · Cited by 122 · see citing works
Phenotypic and genetic classification of diabetes
Deutsch, A. J., Ahlqvist, E., & Udler, M. S. (2022) · Diabetologia · doi:10.1007/s00125-022-05769-4 · Cited by 108 · see citing works
Remission of subclinical adrenocortical failure in subjects with adrenal autoantibodies.
De Bellis, A., Bizzarro, A., Rossi, R., Paglionico, V. A., Criscuolo, T., Lombardi, G., & Bellastella, A. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.76.4.8473373 · Cited by 106 · see citing works
β-Cell failure in type 2 diabetes
Leibowitz, G., Kaiser, N., & Cerasi, E. (2011) · Journal of Diabetes Investigation · doi:10.1111/j.2040-1124.2010.00094.x · Cited by 78 · see citing works
Tsirogianni, A., Pipi, E., & Soufleros, K. (2009) · Autoimmunity Reviews · doi:10.1016/j.autrev.2009.02.019 · Cited by 56 · see citing works
Andersson, C., Kolmodin, M., Ivarsson, S.-A., Carlsson, A., Forsander, G., Lindblad, B., Ludvigsson, J., Kockum, I., Marcus, C., Samuelsson, U., et al. (2014) · Pediatric Diabetes · doi:10.1111/pedi.12093 · Cited by 44 · see citing works
Combination immunotherapy for type 1 diabetes
Bone, R. N., & Evans-Molina, C. (2017) · Current Diabetes Reports · doi:10.1007/s11892-017-0878-z · Cited by 41 · see citing works
The kidney as a new target for antidiabetic drugs: SGLT2 inhibitors
Cangoz, S., Chang, Y.-Y., Chempakaseril, S. J., Guduru, R. C., Huynh, L. M., John, J. S., John, S. T., Joseph, M. E., Judge, R., Kimmey, R., et al. (2013) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1111/jcpt.12077 · Cited by 35 · see citing works
Baker, P. R., Baschal, E. E., Fain, P. R., Triolo, T. M., Nanduri, P., Siebert, J. C., Armstrong, T. K., Babu, S. R., Rewers, M. J., Gottlieb, P. A., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-0508 · Cited by 35 · see citing works
Siljander, H., Härkönen, T., Hermann, R., Simell, S., Hekkala, A., Salonsaari, R., Simell, T., Simell, O., Ilonen, J., Veijola, R., et al. (2009) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.998 · Cited by 30 · see citing works
Immunomodulation with human recombinant autoantigens
Lernmark, Å., & Agardh, C.-D. (2005) · Trends in Immunology · doi:10.1016/j.it.2005.08.015 · Cited by 24 · see citing works
- Authors
- Bottazzo, G., Florin-Christensen, A., & Doniach, D.
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1974-11
- Volume
- 304
- Issue
- 7892
- Pages
- 1279-1283
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2019972832
- Cited by
- 1,469
- References
- 0
- Citations by year
- 2026: 16 · 2025: 24 · 2024: 21 · 2023: 20 · 2022: 24 · 2021: 44 · 2020: 19 · 2019: 25 · 2018: 14 · 2017: 19 · 2016: 22 · 2015: 40 · 2014: 40 · 2013: 30 · 2012: 32
- FWCI
- 20.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- The Lancet
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Health Sciences › Medicine › Surgery › Pancreatic function and diabetes
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Keywords
- islet cell antibodies, type 1 diabetes, organ-specific autoimmunity, insulitis, complement fixation, IgG
- MeSH terms
- Addison Disease, Adolescent, Adrenal Cortex, Adult, Aged, Antibody Specificity, Antibodies, Antinuclear, Autoantibodies, Autoimmune Diseases, Diabetes Mellitus, Diabetes Mellitus, Type 1, Endocrine System Diseases, Female, Fluorescent Antibody Technique, Humans, Immunoglobulin G, Insulin, Islets of Langerhans, Male, Middle Aged, Myxedema, Pancreas, Stomach, Thyroid Gland, Thyroiditis, Diabetes Complications
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
