Cited by 253Smoking Behavior and CessationPharmacogenetics and Drug MetabolismNeurotransmitter Receptor Influence on Behavior

Monoamine oxidase and cigarette smoking

Fowler, Joanna S., Logan, Jean, Wang, Gene-Jack, Volkow, Nora D.·2003·NeuroToxicology

Abstract

Current cigarette smokers have reduced monoamine oxidase (MAO) and there is evidence that this is a pharmacological effect of tobacco smoke exposure rather than a biological characteristic of smokers. This article summarizes human and animal studies documenting the inhibitory effects of tobacco smoke on MAO and discusses MAO inhibition in the context of smoking epidemiology, MAO inhibitor compounds in tobacco, reinvestigations of low platelet MAO in psychiatric disorders and smoking cessation.

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Crossref · 10.1016/s0161-813x(02)00109-2

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74 of 74 references verified0 citation errors · 0 not checkable

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Authors
Fowler, J. S., Logan, J., Wang, G.-J., & Volkow, N. D.
Affiliations
Brookhaven National Laboratory (US)
Corresponding author
Fowler, Joanna S.
Venue
NeuroToxicology
Publisher
Elsevier BV
Published
2003-01
Volume
24
Issue
1
Pages
75-82
ISSN
0161-813X (ISSN-L)
OpenAlex
W2138349568
Cited by
251
References
73
Citations by year
2026: 1 · 2025: 5 · 2024: 5 · 2023: 4 · 2022: 9 · 2021: 5 · 2020: 29 · 2019: 5 · 2018: 9 · 2017: 9 · 2016: 9 · 2015: 9 · 2014: 13 · 2013: 9 · 2012: 8
FWCI
5.59
Type
journal article
Language
en
Open access
closed
Locations
  • NeuroToxicology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • U.S. Department of Energy
  • National Institute on Drug Abuse
  • Brookhaven National Laboratory
Topics
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacogenetics and Drug Metabolism
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords
monoamine oxidase, cigarette smoking, tobacco smoke, monoamine oxidase inhibition, tobacco smoke constituents, smoking cessation, mental illness
MeSH terms
Animals, Mental Disorders, Brain, Humans, Monoamine Oxidase, Monoamine Oxidase Inhibitors, Smoking, Smoking Cessation

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