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Effect of aging on the blood-brain barrier
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Cites
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
Kang, J., Lemaire, H.-G., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K.-H., Multhaup, G., Beyreuther, K., & Müller-Hill, B. (1987) · Nature · doi:10.1038/325733a0 · Cited by 4,619
Carrier-mediated blood-brain barrier transport of short-chain monocarboxylic organic acids
Oldendorf, W. (1973) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1973.224.6.1450 · Cited by 463
Blood-Brain Glucose Transfer: Repression in Chronic Hyperglycemia
Gjedde, A., & Crone, C. (1981) · Science · doi:10.1126/science.7027439 · Cited by 235
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Cerebral microvascular pathology in aging and Alzheimer's disease
Farkas, E., & Luiten, P. G. M. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00068-x · Cited by 1,102
Is Breakdown of the Blood-Brain Barrier Responsible for Lacunar Stroke, Leukoaraiosis, and Dementia?
Wardlaw, J. M., Sandercock, P. A. G., Dennis, M. S., & Starr, J. (2003) · Stroke · doi:10.1161/01.str.0000058480.77236.b3 · Cited by 628
Identification and localization of Chlamydia pneumoniae in the Alzheimer's brain
Balin, B. J., Gérard, H. C., Arking, E. J., Appelt, D. M., Branigan, P. J., Abrams, J. T., Whittum-Hudson, J. A., & Hudson, A. P. (1998) · Medical Microbiology and Immunology · doi:10.1007/s004300050071 · Cited by 506
Shi, Y., Zhang, L., Pu, H., Mao, L., Hu, X., Jiang, X., Xu, N., Stetler, R. A., Zhang, F., Liu, X., et al. (2016) · Nature Communications · doi:10.1038/ncomms10523 · Cited by 431
Reduced Glucose Transporter at the Blood‐Brain Barrier and in Cerebral Cortex in Alzheimer Disease
Kalaria, R. N., & Harik, S. I. (1989) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1989.tb07399.x · Cited by 338
Brown, R. C., Morris, A. P., & O'Neil, R. G. (2007) · Brain Research · doi:10.1016/j.brainres.2006.10.083 · Cited by 291
Mechanisms of mitochondrial dysfunction and energy deficiency in Alzheimer’s disease
Atamna, H., & Frey, W. H. (2007) · Mitochondrion · doi:10.1016/j.mito.2007.06.001 · Cited by 278
Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues
Chen, M. B., Yang, A. C., Yousef, H., Lee, D., Chen, W., Schaum, N., Lehallier, B., Quake, S. R., & Wyss-Coray, T. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.03.012 · Cited by 233
“Indeed, while age-related BBB dysfunction has been probed with a diverse toolkit of tracers (Bien-Ly et al., 2015; Marques et al., 2013; Montagne et al., 2015; Mooradian, 1988), the transcriptional response of vessel segment-specific BECs to aging and changes in the systemic environment have not yet been explored in-d…”
Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy
Blair, L. J., Frauen, H. D., Zhang, B., Nordhues, B. A., Bijan, S., Lin, Y.-C., Zamudio, F., Hernandez, L. D., Sabbagh, J. J., Selenica, M.-L. B., et al. (2015) · Acta Neuropathologica Communications · doi:10.1186/s40478-015-0186-2 · Cited by 193
Zimmerman, B., Rypma, B., Gratton, G., & Fabiani, M. (2021) · Psychophysiology · doi:10.1111/psyp.13796 · Cited by 179
Inflammatory processes in the aging mouse brain: Participation of dendritic cells and T-cells
Stichel, C. C., & Luebbert, H. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.07.022 · Cited by 151
ApoE deficiency leads to a progressive age-dependent blood-brain barrier leakage
Hafezi-Moghadam, A., Thomas, K. L., & Wagner, D. D. (2007) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00563.2005 · Cited by 149
Lipid Transport and Metabolism at the Blood-Brain Interface: Implications in Health and Disease
Pifferi, F., Laurent, B., & Plourde, M. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.645646 · Cited by 148
Pan, Y., & Nicolazzo, J. A. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.04.009 · Cited by 131
Kovacs, G. G., Robinson, J. L., Xie, S. X., Lee, E. B., Grossman, M., Wolk, D. A., Irwin, D. J., Weintraub, D., Kim, C. F., Schuck, T., et al. (2017) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlx007 · Cited by 132
Blood-brain barrier leakage in Alzheimer’s disease: From discovery to clinical relevance
Nehra, G., Bauer, B., & Hartz, A. M. S. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108119 · Cited by 127
Acharya, N. K., Levin, E. C., Clifford, P. M., Han, M., Tourtellotte, R., Chamberlain, D., Pollaro, M., Coretti, N. J., Kosciuk, M. C., Nagele, E. P., et al. (2013) · Journal of Alzheimer's Disease · doi:10.3233/jad-122254 · Cited by 121
Add Alzheimer's disease to the list of autoimmune diseases
D’Andrea, M. R. (2005) · Medical Hypotheses · doi:10.1016/j.mehy.2004.08.024 · Cited by 113
Understanding Immune‐Driven Brain Aging by Human Brain Organoid Microphysiological Analysis Platform
Ao, Z., Song, S., Tian, C., Cai, H., Li, X., Miao, Y., Wu, Z., Krzesniak, J., Ning, B., Gu, M., et al. (2022) · Advanced Science · doi:10.1002/advs.202200475 · Cited by 77
Role of pattern recognition receptors of the neurovascular unit in inflamm-aging
Wilhelm, I., Nyúl-Tóth, Á., Kozma, M., Farkas, A. E., & Krizbai, I. A. (2017) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00106.2017 · Cited by 56
The increasing role of Kappa free light chains in the diagnosis of multiple sclerosis
Konen, F. F., Schwenkenbecher, P., Jendretzky, K. F., Gingele, S., Sühs, K.-W., Tumani, H., Süße, M., & Skripuletz, T. (2021) · Cells · doi:10.3390/cells10113056 · Cited by 47
Metadata
- Authors
- Mooradian, A. D.
- Venue
- Neurobiology of Aging
- Publisher
- Elsevier BV
- Published
- 1988-01
- Volume
- 9
- Issue
- 1
- Pages
- 31-39
- ISSN
- 0197-4580 (ISSN-L)
- OpenAlex
- W2069335131
- Cited by
- 296
- References
- 3
- FWCI
- 10.99
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
