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Cited by 43Connexins and lens biologyCircadian rhythm and melatoninEstrogen and related hormone effects

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Effects of estrogen and progesterone on the expression of connexin-36 mRNA in the suprachiasmatic nucleus of female rats

Shinohara, Kazuyuki, Funabashi, Toshiya, Nakamura, Takahiro J., Kimura, Fukuko·2001·Neuroscience Letters
DOI 10.1016/s0304-3940(01)02022-5
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Abstract

To determine the effects of ovarian steroid hormones on gap junction communication in the suprachiasmatic nucleus (SCN), we examined the effects of estrogen and/or progesterone on the expression of connexin-36 mRNA in the SCN and cerebral cortex (CX) of female rats. Ovariectomized adult rats were injected with 20 microg 17beta-Estradiol or sesame oil 48 h before sacrifice and further injected with 1.5 mg progesterone or sesame oil 24 h before sacrifice. Northern blot revealed that estrogen significantly increased the expression of connexin-36 mRNA in the SCN and this increase was inhibited by progesterone. On the other hand, the connexin-36 mRNA level in the CX was not affected by estrogen or progesterone. These results suggest that the gap junction with connexin-36 in the SCN is specifically regulated by ovarian steroid hormones of female rats.

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Crossref · 10.1016/s0304-3940(01)02022-5

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19 of 19 references verified0 citation errors · 0 not checkable

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  • Estrogen enhances electrical intercellular coupling by increasing the number of gap junctions in the SCN, in a manner opposed by progesterone.

    “Estrogen enhances electrical intercellular coupling by increasing the number of gap junctions in the SCN, [175, 176] in a manner that is opposed by progesterone [176].”

    From The neuroendocrine control of the circadian system: Adolescent chronotype (2012) · cites this paper as [176]

  • Estrogen enhances electrical intercellular coupling by increasing the number of gap junctions in the SCN, in a manner opposed by progesterone.

    “Estrogen enhances electrical intercellular coupling by increasing the number of gap junctions in the SCN, [175, 176] in a manner that is opposed by progesterone [176].”

    From The neuroendocrine control of the circadian system: Adolescent chronotype (2012) · cites this paper as [175]

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Metadata

Authors
Shinohara, K., Funabashi, T., Nakamura, T. J., & Kimura, F.
Affiliations
  • Dokkyo University (JP)
  • Yokohama City University (JP)
Corresponding author
Shinohara, Kazuyuki
ORCID
Venue
Neuroscience Letters
Publisher
Elsevier BV
Published
2001-08
Volume
309
Issue
1
Pages
37-40
ISSN
0304-3940 (ISSN-L)
DOI
10.1016/s0304-3940(01)02022-5
OpenAlex
W2014349217
Cited by
43
References
19
Citations by year
2024: 1 · 2021: 2 · 2020: 1 · 2019: 1 · 2017: 3 · 2016: 2 · 2015: 2 · 2014: 2 · 2013: 2 · 2012: 3
FWCI
0.69
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Neuroscience Letters (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Connexins and lens biology
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
Keywords
estrogen, progesterone, connexin 36, suprachiasmatic nucleus, gap junctional intercellular communication, ovarian steroids, estradiol, cerebral cortex, mRNA expression, female rats
MeSH terms
Gap Junction delta-2 Protein, Animals, Biological Clocks, Cell Communication, Cerebral Cortex, Circadian Rhythm, Estrogens, Estrus, Eye Proteins, Female, Gene Expression Regulation, Neurons, Progesterone, RNA, Messenger, Suprachiasmatic Nucleus, Rats, Wistar, Gap Junctions, Connexins, Reverse Transcriptase Polymerase Chain Reaction, Rats

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