PET study of the localization and laterality of lingual somatosensory processing in humans
Abstract
Regional cerebral blood flow (rCBF) was measured using positron emission tomography (PET) during four tasks in right-handed volunteers with eyes closed: resting, protruding the tongue, stroking the left side of the protruding tongue, and stroking the right side of the protruding tongue. The primary somatosensory tongue representation (S1) mapped to the contralateral central sulcus (Brodmann (BA) 3/4) at approximately 28 mm above the intercommissural plane. Of note, stimulation of the left side of the tongue produced also an ipsilateral S1 response. Analysis of variance (ANOVA) of rCBF at S1 across all four conditions yielded only a significant effect for tongue stimulation, with no effect of laterality; the usually large asymmetries (contralateral >> ipsilateral) in S1 did not surface. We hypothesize that this atypical activation pattern arises from the tongue's specialization for language.
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Tongue movement activation is bilateral rather than left lateralized.
“Contrary to previous findings, activation was observed bilaterally rather than being left lateralized.”
From A review and synthesis of the first 20years of PET and fMRI studies of heard speech, spoken language and reading (2012) · cites this paper as Pardo et al., 1997
The control of the tongue is localized in the central sulcus (BA 3/4) at approximately 28 mm above the intercommissural plane.
“The control of the tongue was localized in the central sulcus (BA 3/4) at approximately 28 mm above the intercommissural plane (Pardo et al., 1997).”
From A review and synthesis of the first 20years of PET and fMRI studies of heard speech, spoken language and reading (2012) · cites this paper as Pardo et al., 1997
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- Authors
- Pardo, J. V., Wood, T. D., Costello, P. A., Pardo, P. J., & Lee, J. T.
- Affiliations
- University of Minnesota (US)
- Corresponding author
- Pardo, José V
- ORCID
- Pardo, José V
- Venue
- Neuroscience Letters
- Publisher
- Elsevier BV
- Published
- 1997-09
- Volume
- 234
- Issue
- 1
- Pages
- 23-26
- ISSN
- 0304-3940 (ISSN-L)
- OpenAlex
- W1967726693
- Cited by
- 64
- References
- 18
- Citations by year
- 2024: 2 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 1 · 2019: 1 · 2016: 3 · 2015: 3 · 2013: 2 · 2012: 3
- FWCI
- 0.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroscience Letters (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (P30DK050456, P30 DK50456-02)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hemispheric Asymmetry in Neuroscience
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Keywords
- primary somatosensory cortex, regional cerebral blood flow, tongue stimulation, contralateral activation, ipsilateral activation, hemispheric lateralization, central sulcus, language lateralization, tongue protrusion
- MeSH terms
- Adolescent, Adult, Analysis of Variance, Cerebrovascular Circulation, Female, Humans, Functional Laterality, Male, Mental Processes, Reference Values, Somatosensory Cortex, Tomography, Emission-Computed, Tongue
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