Cited by 64Tactile and Sensory InteractionsHemispheric Asymmetry in NeuroscienceNeurobiology of Language and Bilingualism

PET study of the localization and laterality of lingual somatosensory processing in humans

Pardo, José V, Wood, Timothy D, Costello, Patricia A, Pardo, Patricia J, Lee, Joel T·1997·Neuroscience Letters

Abstract

Regional cerebral blood flow (rCBF) was measured using positron emission tomography (PET) during four tasks in right-handed volunteers with eyes closed: resting, protruding the tongue, stroking the left side of the protruding tongue, and stroking the right side of the protruding tongue. The primary somatosensory tongue representation (S1) mapped to the contralateral central sulcus (Brodmann (BA) 3/4) at approximately 28 mm above the intercommissural plane. Of note, stimulation of the left side of the tongue produced also an ipsilateral S1 response. Analysis of variance (ANOVA) of rCBF at S1 across all four conditions yielded only a significant effect for tongue stimulation, with no effect of laterality; the usually large asymmetries (contralateral >> ipsilateral) in S1 did not surface. We hypothesize that this atypical activation pattern arises from the tongue's specialization for language.

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Crossref · 10.1016/s0304-3940(97)00650-2

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Authors
Pardo, J. V., Wood, T. D., Costello, P. A., Pardo, P. J., & Lee, J. T.
Affiliations
University of Minnesota (US)
Corresponding author
Pardo, José V
Venue
Neuroscience Letters
Publisher
Elsevier BV
Published
1997-09
Volume
234
Issue
1
Pages
23-26
ISSN
0304-3940 (ISSN-L)
OpenAlex
W1967726693
Cited by
64
References
18
Citations by year
2024: 2 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 1 · 2019: 1 · 2016: 3 · 2015: 3 · 2013: 2 · 2012: 3
FWCI
0.68
Type
journal article
Language
en
Open access
closed
Locations
  • Neuroscience Letters (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Diabetes and Digestive and Kidney Diseases (P30DK050456, P30 DK50456-02)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Hemispheric Asymmetry in Neuroscience
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
Keywords
primary somatosensory cortex, regional cerebral blood flow, tongue stimulation, contralateral activation, ipsilateral activation, hemispheric lateralization, central sulcus, language lateralization, tongue protrusion
MeSH terms
Adolescent, Adult, Analysis of Variance, Cerebrovascular Circulation, Female, Humans, Functional Laterality, Male, Mental Processes, Reference Values, Somatosensory Cortex, Tomography, Emission-Computed, Tongue

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