Participation of the prefrontal cortices in prospective memory: evidence from a PET study in humans
Abstract
Prospective memory is a memory feature in humans which involves activities for remembering to do something in the future. The present study provides functional neuroanatomy of prospective memory for the first time. We used positron emission tomography (PET) and found several localized brain activations in relation to a prospective memory task required to retain and remember a planned action while performing an ongoing routine activity. Activations were identified in the right dorsolateral and ventrolateral prefrontal cortices, the left frontal pole and anterior cingulate gyrus, the left parahippocampal gyrus, and midline medial frontal lobe. We attributed these activations to several cognitive processes involved in prospective memory, such as holding an intention toward future behavior, checking target items within presented stimuli, and dividing attention between the planned action and the routine activity.
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Performance of unaided tasks requiring the fulfilment of delayed intentions has been linked to signal change in rostral prefrontal cortex.
“performance of unaided tasks requiring the fulfilment of delayed intentions has been linked to signal change in rostral prefrontal cortex (Burgess, Quayle, & Frith, 2001; Gilbert, 2011; Okuda et al., 1998)”
From Strategic offloading of delayed intentions into the external environment (2015) · cites this paper as Okuda et al., 1998
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Ecological prospective memory assessment in patients with traumatic brain injury
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Neural substrates of implicit cueing effect on prospective memory
Hashimoto, T., Umeda, S., & Kojima, S. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.07.047 · Cited by 49 · see citing works
Prospective memory in schizophrenia: Further clarification of nature of impairment
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Prospective memory in schizophrenia: The impact of varying retrospective-memory load
Altgassen, M., Kliegel, M., Rendell, P. G., Henry, J. D., & Zöllig, J. (2008) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390701779552 · Cited by 46 · see citing works
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- Authors
- Okuda, J., Fujii, T., Yamadori, A., Kawashima, R., Tsukiura, T., Fukatsu, R., Suzuki, K., Ito, M., & Fukuda, H.
- Affiliations
- Tohoku University (JP)
- Corresponding author
- Okuda, Jiro
- Venue
- Neuroscience Letters
- Publisher
- Elsevier BV
- Published
- 1998-09
- Volume
- 253
- Issue
- 2
- Pages
- 127-130
- ISSN
- 0304-3940 (ISSN-L)
- OpenAlex
- W2046071456
- Cited by
- 263
- References
- 21
- Citations by year
- 2025: 2 · 2024: 5 · 2023: 6 · 2022: 5 · 2021: 4 · 2020: 8 · 2019: 4 · 2018: 5 · 2017: 6 · 2016: 13 · 2015: 11 · 2014: 14 · 2013: 12 · 2012: 14
- FWCI
- 6.05
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroscience Letters (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Education, Culture, Sports, Science and Technology (JSPS-RFTF97L00202)
- Japan Society for the Promotion of Science
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Keywords
- prospective memory, prefrontal cortex, dorsolateral prefrontal cortex, ventrolateral prefrontal cortex, frontal pole, anterior cingulate cortex, parahippocampal gyrus, medial frontal lobe, divided attention, functional neuroanatomy
- MeSH terms
- Adult, Attention, Brain Mapping, Frontal Lobe, Gyrus Cinguli, Humans, Male, Memory, Motor Activity, Task Performance and Analysis, Tomography, Emission-Computed, Prefrontal Cortex
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