Paroxysmal supraventricular tachycardia in the general population
Open accessAbstract
Objectives We sought to determine the epidemiology and clinical significance of paroxysmal supraventricular tachycardia (PSVT) in the general population.Background Current knowledge of PSVT has been derived primarily from otherwise healthy patients referred to specialized centers.Methods We used the resources of the Marshfield Epidemiologic Study Area, a region covering practically all medical care received by its 50,000 residents. A review of 1,763 records identified prevalent cases as of July 1, 1991 and all new cases of PSVT diagnosed from that day until June 30, 1993. A mean follow-up period of 2 years was completed in all incident patients. Patients without other cardiovascular disease were labeled as having "lone PSVT."Results The prevalence was 2.25/1,000 persons and the incidence was 35/100,000 person-years (95% confidence interval, 23 to 47/100,000). Other cardiovascular disease was present in 90% of males and 48% of females (p = 0.0495). Compared with patients with other cardiovascular disease, those with lone PSVT were younger (mean 37 vs. 69 years, p = 0.0002), had a faster PSVT heart rate (mean 186 vs. 155 beats/min, p = 0.0006) and were more likely to have their condition first documented in the emergency room (69% vs. 30%, p = 0.0377). The onset of symptoms occurred during the childbearing years in 58% of females with lone PSVT versus 9% of females with other cardiovascular disease (p = 0.0272).Conclusions There are approximately 89,000 new cases/year and 570,000 persons with PSVT in the United States. In the general population, there are two distinct subsets of patients with PSVT: those with other cardiovascular disease and those with lone PSVT. Our data suggest etiologic heterogeneity in the pathogenesis of PSVT and the need for more population-based research on this common condition.
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Compared with patients with other cardiovascular disease, those with lone paroxysmal SVT had a faster paroxysmal SVT heart rate (mean 186 vs 155 beats/min).
“had a faster paroxysmal SVT heart rate (mean 186 vs. 155 beats/min)”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [4]
Females had a 2-fold greater relative risk of paroxysmal SVT than males.
“Overall, females had 2-fold greater relative risk (RR) of paroxysmal SVT compared with males.”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [4]
Compared with patients with other cardiovascular disease, those with lone paroxysmal SVT were younger (mean 37 vs 69 years).
“Compared with patients with other cardiovascular disease, those with lone paroxysmal SVT were younger (mean 37 vs. 69 years)”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [4]
In the Marshfield Epidemiologic Study Area, among a 3.5% sample of medical records, paroxysmal SVT prevalence was 2.25 per 1000 persons and incidence was 35 per 100,000 person-years.
“In a 3.5% sample of medical records in the Marshfield (Wisconsin) Epidemiologic Study Area (MESA) the prevalence of paroxysmal SVT was 2.25/1000 persons, and the incidence was 35/100 000 person-years. 4”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [4]
From those older MESA data, an estimated 89,000 new paroxysmal SVT cases occur annually and 570,000 patients have paroxysmal SVT in the USA.
“Based on these old data, it was estimated that there are 89 000 new cases per year, and 570 000 patients with paroxysmal SVT in the USA.”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [4]
In MESA, other cardiovascular disease was present in 90% of males and 48% of females with paroxysmal SVT.
“In MESA, other cardiovascular disease was present in 90% of males, and 48% of females.”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [4]
Onset of symptoms occurred during childbearing years in 58% of females with lone paroxysmal SVT versus 9% of females with other cardiovascular disease.
“The onset of symptoms occurred during the childbearing years in 58% of females with lone paroxysmal SVT, vs. 9% of females with other cardiovascular disease.”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [4]
Compared with patients with other cardiovascular disease, those with lone paroxysmal SVT were more likely to have their condition first documented in the emergency room (69% vs 30%).
“and were more likely to have their condition first documented in the emergency room (69% vs. 30%).”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [4]
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Diagnosis and management of supraventricular tachycardia
Whinnett, Z. I., Sohaib, S. M. A., & Davies, D. W. (2012) · BMJ · doi:10.1136/bmj.e7769 · Cited by 47 · see citing works
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Cost-Effectiveness of Radiofrequency Ablation for Supraventricular Tachycardia in Guatemala
Rodriguez, B. C., Leal, S., Calvimontes, G., & Hutton, D. (2015) · Value in Health Regional Issues · doi:10.1016/j.vhri.2015.06.002 · Cited by 11 · see citing works
- Authors
- Orejarena, L. A., Vidaillet, H., DeStefano, F., Nordstrom, D. L., Vierkant, R. A., Smith, P. N., & Hayes, J. J.
- Affiliations
- Marshfield Clinic (US)
- Corresponding author
- Hayes, John J
- ORCID
- Vierkant, Robert A
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 1998-01
- Volume
- 31
- Issue
- 1
- Pages
- 150-157
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2103695603
- Cited by
- 432
- References
- 57
- Citations by year
- 2026: 18 · 2025: 11 · 2024: 26 · 2023: 23 · 2022: 13 · 2021: 25 · 2020: 29 · 2019: 26 · 2018: 25 · 2017: 32 · 2016: 26 · 2015: 28 · 2014: 9 · 2013: 20 · 2012: 16
- FWCI
- 3.28
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Keywords
- paroxysmal supraventricular tachycardia, prevalence, incidence, cardiovascular comorbidity, etiologic heterogeneity, emergency department presentation, heart rate
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Female, Humans, Infant, Male, Middle Aged, Tachycardia, Paroxysmal, Tachycardia, Supraventricular, Wisconsin, Incidence, Prevalence
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