Excess hospital admissions during the July 1995 heat wave in Chicago
Abstract
Introduction This study describes medical conditions treated in all 47 non-VA hospitals in Cook County, IL during the 1995 heat wave. We characterize the underlying diseases of the susceptible population, with the goal of tailoring prevention efforts.Methods Primary and secondary discharge diagnoses made during the heat wave and comparison periods were obtained from computerized inpatient hospital discharge data to determine reasons for hospitalization, and comorbid conditions, respectively.Results During the week of the heat wave, there were 1072 (11%) more hospital admissions than average for comparison weeks and 838 (35%) more than expected among patients aged 65 years and older. The majority of this excess (59%) were treatments for dehydration, heat stroke, and heat exhaustion; with the exception of acute renal failure no other primary discharge diagnoses were significantly elevated. In contrast, analysis of comorbid conditions revealed 23% (p = 0.019) excess admissions of underlying cardiovascular diseases, 30% (p = 0.033) of diabetes, 52% (p = 0.011) of renal diseases, and 20% (p = 0.027) of nervous system disorders. Patient admissions for emphysema (p = 0.007) and epilepsy (p = 0.009) were also significantly elevated during the heat wave week.Conclusions The majority of excess hospital admissions were due to dehydration, heat stroke, and heat exhaustion, among people with underlying medical conditions. Short-term public health interventions to reduce heat-related morbidity should be directed toward these individuals to assure access to air conditioning and adequate fluid intake. Long-term prevention efforts should aim to improve the general health condition of people at risk through, among other things, regular physician-approved exercise.
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People with diabetes mellitus have lower skin blood flow and dysregulated thermoregulatory responses during heat exposure.
“Furthermore, people with DM have been reported to have lower skin blood flow and dysregulated thermoregulatory responses during heat exposure, which is associated with dysregulated thermal, cardiovascular, and glycemic control6–8.”
From Sleep and temperature data from wearable devices support noninvasive detection of diabetes mellitus in a large-scale, retrospective analysis (2026) · cites this paper as [7]
Cites
Heat-Related Deaths during the July 1995 Heat Wave in Chicago
Semenza, J. C., Rubin, C., Falter, K. H., Selanikio, J., Flanders, W. D., Howe, H. L., & Wilhelm, J. (1996) · New England Journal of Medicine · doi:10.1056/nejm199607113350203 · Cited by 1,381 · see citing works
Self-citationReduced Thirst after Water Deprivation in Healthy Elderly Men
Phillips, P. A., Rolls, B. J., Ledingham, J. G. G., Forsling, M. L., Morton, J. J., Crowe, M. J., & Wollner, L. (1984) · New England Journal of Medicine · doi:10.1056/nejm198409203111202 · Cited by 780 · see citing works
Human Circulation: Regulation During Physical Stress
Rowell, L. B. (1986) · Medical Entomology and Zoology · Cited by 672 · see citing works
Mortality in Chicago attributed to the July 1995 heat wave.
Whitman, S., Good, G., Donoghue, E. R., Benbow, N., Shou, W., & Mou, S. (1997) · American Journal of Public Health · doi:10.2105/ajph.87.9.1515 · Cited by 507 · see citing works
Keatinge, W. R., Coleshaw, S., Easton, J. C., Cotter, F. E., Mattock, M. B., & Chelliah, R. (1986) · The American Journal of Medicine · doi:10.1016/0002-9343(86)90348-7 · Cited by 400 · see citing works
Morbidity and Mortality Associated With the July 1980 Heat Wave in St Louis and Kansas City, Mo
Jones, T. (1982) · JAMA · doi:10.1001/jama.1982.03320490025030 · Cited by 315 · see citing works
Risk factors for heatstroke. A case-control study
Kilbourne, E. M. (1982) · JAMA · doi:10.1001/jama.247.24.3332 · Cited by 306 · see citing works
Mortality from heat illness and heat-aggravated illness in the United States
Ellis, F. P. (1972) · Environmental Research · doi:10.1016/0013-9351(72)90019-9 · Cited by 187 · see citing works
Some effects of the urban structure on heat mortality
Clarke, J. F. (1972) · Environmental Research · doi:10.1016/0013-9351(72)90023-0 · Cited by 185 · see citing works
Age-related decline in left ventricular filling at rest and exercise
Schulman, S. P., Lakatta, E. G., Fleg, J. L., Lakatta, L. E., Becker, L. C., & Gerstenblith, G. (1992) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1992.263.6.h1932 · Cited by 181 · see citing works
Reduced osmotic thirst in healthy elderly men
Phillips, P. A., Bretherton, M., Johnston, C. I., et al. (1991) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1991.261.1.r166 · Cited by 173 · see citing works
Air-conditioning and Mortality in Hot Weather
Rogot, E., Sorlie, P. D., & Backlund, E. (1992) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116413 · Cited by 154 · see citing works
Schuman, S. H. (1972) · Environmental Research · doi:10.1016/0013-9351(72)90020-5 · Cited by 152 · see citing works
Ambient Temperature and Mortality From Unintentional Cocaine Overdose
Marzuk, P. M. (1998) · JAMA · doi:10.1001/jama.279.22.1795 · Cited by 136 · see citing works
Reliability of Information Abstracted from Patients?? Medical Records
Demlo, L. K., Campbell, P. M., & Brown, S. S. (1978) · Medical Care · doi:10.1097/00005650-197812000-00003 · Cited by 134 · see citing works
Control of heat-induced cutaneous vasodilatation in relation to age
Kenney, W. L. (1988) · European Journal of Applied Physiology · doi:10.1007/bf00691250 · Cited by 118 · see citing works
Maximal skin vascular conductance in subjects aged 5-85 yr
Martin, H. L., Loomis, J. L., & Kenney, W. L. (1995) · Journal of Applied Physiology · doi:10.1152/jappl.1995.79.1.297 · Cited by 108 · see citing works
Age and hypohydration independently influence the peripheral vascular response to heat stress
Kenney, W. L., Tankersley, C. G., Newswanger, D. L., Hyde, D. E., Puhl, S. M., & Turner, N. L. (1990) · Journal of Applied Physiology · doi:10.1152/jappl.1990.68.5.1902 · Cited by 108 · see citing works
Age alters regional distribution of blood flow during moderate-intensity exercise
Kenney, W. L., & Ho, C. W. (1995) · Journal of Applied Physiology · doi:10.1152/jappl.1995.79.4.1112 · Cited by 103 · see citing works
Analysis of the 1980 Heat Wave in Memphis*
Applegate, W. B., Runyan, J. W., Kuder, L. B., Williams, M. L., Konigsberg, C., & Fouche, C. (1981) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1981.tb01238.x · Cited by 102 · see citing works
3 Thermoregulation at Rest and during Exercise in Healthy Older Adults
Kenney, W. L. (1997) · Exercise and Sport Sciences Reviews · doi:10.1249/00003677-199700250-00005 · Cited by 102 · see citing works
Dye curves: The theory and practice of indicator dilution
Bloomfield, D. A. (1975) · American Heart Journal · doi:10.1016/0002-8703(75)90175-1 · Cited by 94 · see citing works
The effete in the heat: heat‐related hospital presentations during a ten day heat wave
Faunt, J., WILKINSON, T. J., Aplin, P., Henschke, P. J., Webb, M., & Penhall, R. K. (1995) · Australian and New Zealand Journal of Medicine · doi:10.1111/j.1445-5994.1995.tb02822.x · Cited by 85 · see citing works
Aging and human heat tolerance
PANDOLF, K. B. (1997) · Experimental Aging Research · doi:10.1080/03610739708254027 · Cited by 84 · see citing works
Effects of drinking on thirst and vasopressin in dehydrated elderly men
Phillips, P. A., Bretherton, M., Risvanis, J., et al. (1993) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1993.264.5.r877 · Cited by 77 · see citing works
Shen, T., Howe, H. L., Alo, C. J., & Moolenaar, R. L. (1998) · American Journal of Forensic Medicine & Pathology · doi:10.1097/00000433-199806000-00003 · Cited by 75 · see citing works
Maximal skin blood flow is decreased in elderly men
Rooke, G. A., Savage, M. V., & Brengelmann, G. L. (1994) · Journal of Applied Physiology · doi:10.1152/jappl.1994.77.1.11 · Cited by 67 · see citing works
Activation of coagulation during therapeutic whole body hyperthermia
Strother, S. V., Bull, J. M., & Branham, S. (1986) · Thrombosis Research · doi:10.1016/0049-3848(86)90155-6 · Cited by 63 · see citing works
Mortality and Morbidity in Birmingham during the 1976 Heatwave
Ellis, F. P., PRINCÉ, H. P., LOVATT, G., & Whittington, R. M. (1980) · QJM · doi:10.1093/oxfordjournals.qjmed.a067600 · Cited by 63 · see citing works
Langlois, J. A., Buechner, J. S., O’Connor, E., et al. (1995) · American Journal of Public Health · doi:10.2105/ajph.85.9.1261 · Cited by 58 · see citing works
Dye curves: The theory and practice of indicator dilution
Bloomfield, D. A. (1974) · Cited by 57 · see citing works
Acclimatization of older men to work in heat
Robinson, S., Belding, H. S., Consolazio, F. C., et al. (1965) · Journal of Applied Physiology · doi:10.1152/jappl.1965.20.4.583 · Cited by 47 · see citing works
Morbidity and mortality associated with the July 1980 heat wave in St Louis and Kansas City, Mo
Jones, T. S. (1982) · JAMA · doi:10.1001/jama.247.24.3327 · Cited by 45 · see citing works
Epidemiology of Successive Heat Waves in Michigan in 1962 and 1963
Schuman, S. H., Anderson, C. P., & Oliver, J. T. (1964) · JAMA · doi:10.1001/jama.1964.03070100027005 · Cited by 39 · see citing works
Geographic Distribution of Heat-Related Deaths Among Elderly Persons
Martinez, B. (1989) · JAMA · doi:10.1001/jama.1989.03430160068032 · Cited by 31 · see citing works
HEATWAVE MORBIDITY AND MORTALITY IN OLD AGE
FISH, P. D., Bennett, G. C. J., & Millard, P. H. (1985) · Age and Ageing · doi:10.1093/ageing/14.4.243 · Cited by 24 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Mapping community determinants of heat vulnerability
Reid, C. E., O’Neill, M. S., Gronlund, C. J., Brines, S. J., Brown, D. G., Diez-Roux, A. V., & Schwartz, J. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0900683 · Cited by 805 · see citing works
Ambient Temperature and Morbidity: A Review of Epidemiological Evidence
Ye, X., Wolff, R., Yu, W., Vaneckova, P., Pan, X., & Tong, S. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1003198 · Cited by 660 · see citing works
McGeehin, M. A., & Mirabelli, M. (2001) · Environmental Health Perspectives · doi:10.1289/ehp.109-1240665 · Cited by 669 · see citing works
Anatomy and Physiology of the Skin
Kolarsick, P. A. J., Kolarsick, M. A., & Goodwin, C. (2011) · Journal of the Dermatology Nurses' Association · doi:10.1097/jdn.0b013e3182274a98 · Cited by 578 · see citing works
Heat waves in the United States: definitions, patterns and trends
Smith, T. T., Zaitchik, B. F., & Gohlke, J. M. (2013) · Climatic Change · doi:10.1007/s10584-012-0659-2 · Cited by 396 · see citing works
Temperature extremes and health: impacts of climate variability and change in the United States
O’Neill, M. S., & Ebi, K. L. (2009) · Journal of Occupational & Environmental Medicine · doi:10.1097/jom.0b013e318173e122 · Cited by 297 · see citing works
Body temperature regulation in diabetes
Kenny, G. P., Sigal, R. J., & McGinn, R. (2016) · Temperature · doi:10.1080/23328940.2015.1131506 · Cited by 297 · see citing works
“In fact, individuals with type 2 diabetes have up to a 56% greater risk for hospitalization and/or mortality during a heat wave.(106) One recent study assessed the influence of age and type 2 diabetes during passive heat exposure in a room set at 43 C for 3 hours.”
BackgroundGubernot, D. M., Anderson, G. B., & Hunting, K. L. (2015) · American Journal of Industrial Medicine · doi:10.1002/ajim.22381 · Cited by 259 · see citing works
Tapia, C., Abajo, B., Feliu, E., Mendizabal, M., Martinez, J. A., Fernández, J. G., Laburu, T., & Lejarazu, A. (2017) · Ecological Indicators · doi:10.1016/j.ecolind.2017.02.040 · Cited by 238 · see citing works
Wang, X., Lavigne, E., Ouellette-kuntz, H., & Chen, B. E. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.10.042 · Cited by 215 · see citing works
Vanos, J., Guzman-Echavarria, G., Baldwin, J. W., Bongers, C., Ebi, K. L., & Jay, O. (2023) · Nature Communications · doi:10.1038/s41467-023-43121-5 · Cited by 206 · see citing works
Kinney, P. L., O’Neill, M. S., Bell, M. L., & Schwartz, J. (2008) · Environmental Science & Policy · doi:10.1016/j.envsci.2007.08.001 · Cited by 194 · see citing works
Children's health and vulnerability in outdoor microclimates: a comprehensive review
Vanos, J. K. (2015) · Environment International · doi:10.1016/j.envint.2014.11.016 · Cited by 184 · see citing works
Kjellstrom, T., Butler, A. J., Lucas, R. M., & Bonita, R. (2010) · International Journal of Public Health · doi:10.1007/s00038-009-0090-2 · Cited by 159 · see citing works
Time-series analysis of weather and mortality patterns in Nairobi's informal settlements
Egondi, T., Kyobutungi, C., Kovats, S., Muindi, K., Ettarh, R., & Rocklöv, J. (2012) · Global Health Action · doi:10.3402/gha.v5i0.19065 · Cited by 119 · see citing works
Montero, J. C., Mirón, I. J., Criado-Álvarez, J. J., Linares, C., & Díaz, J. (2012) · Science of The Total Environment · doi:10.1016/j.scitotenv.2011.10.009 · Cited by 83 · see citing works
Heat and emergency room admissions in the Netherlands
van Loenhout, J. A. F., Delbiso, T. D., Kiriliouk, A., Rodriguez-Llanes, J. M., Segers, J., & Guha-Sapir, D. (2018) · BMC Public Health · doi:10.1186/s12889-017-5021-1 · Cited by 58 · see citing works
Zuhra, S. S., Tabinda, A. B., & Yasar, A. (2019) · International Journal of Biometeorology · doi:10.1007/s00484-019-01784-0 · Cited by 40 · see citing works
Medical evaluation for exposure extremes: Heat
Pryor, R. R., Bennett, B. L., O’Connor, F. G., Young, J. M. J., & Asplund, C. A. (2015) · Wilderness & Environmental Medicine · doi:10.1016/j.wem.2015.09.009 · Cited by 32 · see citing works
Potential Impacts of Extreme Heat and Bushfires on Dementia
Farugia, T. L., Cuni-Lopez, C., & White, A. R. (2021) · Journal of Alzheimer’s Disease · doi:10.3233/jad-201388 · Cited by 29 · see citing works
Heat waves: a hot topic in climate change research
Marx, W., Haunschild, R., & Bornmann, L. (2021) · Theoretical and Applied Climatology · doi:10.1007/s00704-021-03758-y · Cited by 1 · see citing works
Viswanath, V. K., Navaneethan, S., Burks, J. H., Soltani, S., Kasl, P., Hartogensis, W., Dilchert, S., Hecht, F. M., Mason, A. E., Wang, E. J., et al. (2026) · Communications Medicine · doi:10.1038/s43856-026-01501-0
- Authors
- Semenza, J.
- Affiliations
- Centers for Disease Control and Prevention (US)
- Corresponding author
- Semenza, J
- ORCID
- Semenza, J
- Venue
- American Journal of Preventive Medicine
- Publisher
- Elsevier BV
- Published
- 1999-05
- Volume
- 16
- Issue
- 4
- Pages
- 269-277
- ISSN
- 0749-3797 (ISSN-L)
- OpenAlex
- W2074485797
- Cited by
- 619
- References
- 37
- Citations by year
- 2026: 12 · 2025: 25 · 2024: 29 · 2023: 29 · 2022: 29 · 2021: 33 · 2020: 25 · 2019: 35 · 2018: 30 · 2017: 37 · 2016: 47 · 2015: 39 · 2014: 33 · 2013: 40 · 2012: 24
- FWCI
- 3.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Preventive Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Climate Change and Health Impacts
- Health Sciences › Medicine › Physiology › Thermoregulation and physiological responses
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Effects of Environmental Stressors on Livestock
- Keywords
- heatstroke, heat exhaustion, dehydration, comorbidities, older adults, cardiovascular disease, diabetes mellitus, kidney disease, neurological disorders, emphysema, epilepsy, vulnerable populations
- MeSH terms
- Mental Disorders, Cardiovascular Diseases, Chicago, Diabetes Mellitus, Endocrine System Diseases, Female, Hot Temperature, Hospitalization, Humans, Kidney Diseases, Male, Nervous System Diseases, Registries, Respiratory Tract Diseases, Risk Factors, Weather, Comorbidity, Incidence, Heat Stress Disorders
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