Hypothesis: the mitochondrial NO(*) signaling pathway, and the transduction of nitrosative to oxidative cell signals: an alternative function for cytochrome c oxidase

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

Liu, X., Kim, C. N., Yang, J., Jemmerson, R., & Wang, X. (1996) · Cell · doi:10.1016/s0092-8674(00)80085-9 · Cited by 5,167

The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

Boveris, A., & Chance, B. (1973) · Biochemical Journal · doi:10.1042/bj1340707 · Cited by 2,626

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

Li, Y., Huang, T.-T., Carlson, E. J., Melov, S., Ursell, P. C., Olson, J. L., Noble, L. J., Yoshimura, M. P., Berger, C., Chan, P. H., et al. (1995) · Nature Genetics · doi:10.1038/ng1295-376 · Cited by 1,789

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

Fleury, C., Neverova, M., Collins, S., Raimbault, S., Champigny, O., Lévi-Meyrueis, C., Bouillaud, F., Seldin, M. F., Surwit, R. S., Ricquier, D., et al. (1997) · Nature Genetics · doi:10.1038/ng0397-269 · Cited by 1,630

Oxidants as Stimulators of Signal Transduction

Suzuki, Y. J., Forman, H. J., & Sevanian, A. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00275-4 · Cited by 1,370

Untitled work

Stamler (2001) · doi:10.1016/s0092-8674(01)00495-0 · Cited by 1,261

Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide: Implications for neurodegenerative diseases

Cleeter, M. W. J., Cooper, J. M., Darley-Usmar, V. M., Moncada, S., & Schapira, A. H. V. (1994) · FEBS Letters · doi:10.1016/0014-5793(94)00424-2 · Cited by 1,241

Subcellular Distribution of Superoxide Dismutases (SOD) in Rat Liver

Okado‐Matsumoto, A., & Fridovich, I. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105395200 · Cited by 1,036

Superoxide production by the mitochondrial respiratory chain

Turrens, J. F. (1997) · Bioscience Reports · doi:10.1023/a:1027374931887 · Cited by 903

Superoxide Dismutase

Weisiger, R. A., & Fridovich, I. (1973) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)43969-0 · Cited by 895

Calcium, ATP, and ROS: a mitochondrial love-hate triangle

Brookes, P. S., Yoon, Y., Robotham, J. L., Anders, M. W., & Sheu, S.-S. (2004) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00139.2004 · Cited by 2,575

Deoxymyoglobin Is a Nitrite Reductase That Generates Nitric Oxide and Regulates Mitochondrial Respiration

Shiva, S., Huang, Z., Grubina, R., Sun, J., Ringwood, L. A., MacArthur, P. H., Xu, X., Murphy, E., Darley-Usmar, V. M., & Gladwin, M. T. (2007) · Circulation Research · doi:10.1161/01.res.0000260171.52224.6b · Cited by 599

Mitochondrial Signaling in Mammalian Cells Activated by Red and Near‐IR Radiation

Karu, T. I. (2008) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2008.00394.x · Cited by 575

Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

Shiva, S., Sack, M. N., Greer, J. J., Duranski, M., Ringwood, L. A., Burwell, L., Wang, X., MacArthur, P. H., Shoja, A., Raghavachari, N., et al. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20070198 · Cited by 555

Mitochondrial reactive oxygen species production in excitable cells: Modulators of mitochondrial and cell function

Stowe, D. F., & Camara, A. K. S. (2009) · Antioxidants & Redox Signaling · doi:10.1089/ars.2008.2331 · Cited by 471

Crosstalk signaling between mitochondrial Ca2+ and ROS

Robert, F. F. (2009) · Frontiers in bioscience · doi:10.2741/3303 · Cited by 448

Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury

Hendgen-Cotta, U. B., Merx, M. W., Shiva, S., Schmitz, J., Becher, S., Klare, J. P., Steinhoff, H.-J., Goedecke, A., Schrader, J., Gladwin, M. T., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801336105 · Cited by 418

Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent

King, A. L., Polhemus, D. J., Bhushan, S., Otsuka, H., Kondo, K., Nicholson, C. K., Bradley, J., Islam, K. N., Calvert, J. W., Tao, Y., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1321871111 · Cited by 368

Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions

Mailloux, R. J., Jin, X., & Willmore, W. G. (2013) · Redox Biology · doi:10.1016/j.redox.2013.12.011 · Cited by 321

Mitochondria: regulators of signal transduction by reactive oxygen and nitrogen species

Brookes, P. S., Levonen, A.-L., Shiva, S., Sarti, P., & Darley-Usmar, V. M. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00901-2 · Cited by 298

Absorption of monochromatic and narrow band radiation in the visible and near IR by both mitochondrial and non-mitochondrial photoacceptors results in photobiomodulation

Passarella, S., & Кару, Т. Й. (2014) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2014.07.021 · Cited by 279

Direct evidence for S-nitrosation of mitochondrial complex I

Burwell, L. S., Nadtochiy, S. M., Tompkins, A. J., Young, S., & Brookes, P. S. (2006) · Biochemical Journal · doi:10.1042/bj20051435 · Cited by 274

The generation and inactivation mechanism of oxidation–reduction potential of electrolyzed oxidizing water

Liao, L. B., Chen, W. M., & Xiao, X. (2006) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2006.01.004 · Cited by 262

Mitochondria: a hub of redox activities and cellular distress control

Kakkar, P., & Singh, B. K. (2007) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-007-9520-8 · Cited by 255

Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling

Ghouleh, I. A., Khoo, N. K. H., Knaus, U. G., Griendling, K. K., Touyz, R. M., Thannickal, V. J., Barchowsky, A., Nauseef, W. M., Kelley, E. E., Bauer, P. M., et al. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.06.011 · Cited by 252

Nitric oxide inhibition of respiration involves both competitive (heme) and noncompetitive (copper) binding to cytochrome c oxidase

Mason, M. G., Nicholls, P., Wilson, M. T., & Cooper, C. E. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506562103 · Cited by 233

Oxidative Stress and Carbonyl Lesions in Ulcerative Colitis and Associated Colorectal Cancer

Wang, Z., Li, S., Cao, Y. W., Tian, X., Zeng, R., Liao, D., & Cao, D. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/9875298 · Cited by 228

Mitochondrial Ca2+ and regulation of the permeability transition pore

Hurst, S., Hoek, J. B., & Sheu, S. (2016) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-016-9672-x · Cited by 227

Role of the anion nitrite in ischemia-reperfusion cytoprotection and therapeutics

DEZFULIAN, C., RAAT, N., SHIVA, S., & GLADWIN, M. (2007) · Cardiovascular Research · doi:10.1016/j.cardiores.2007.05.001 · Cited by 198

A Novel Mitochondrial Signaling Pathway Activated by Visible-to-near Infrared Radiation¶

Karu, T. I., Pyatibrat, L. V., & Afanasyeva, N. I. (2004) · Photochemistry and Photobiology · doi:10.1562/2004-03-25-ra-123 · Cited by 197

Mitochondrial signaling pathways: A receiver/integrator organelle

Goldenthal, M. J., & Marín-García, J. (2004) · Molecular and Cellular Biochemistry · doi:10.1023/b:mcbi.0000038228.85494.3b · Cited by 184

miR-181c Regulates the Mitochondrial Genome, Bioenergetics, and Propensity for Heart Failure In Vivo

Das, S., Bedja, D., Campbell, N. R., Dunkerly-Eyring, B. L., Chenna, V., Maitra, A., & Steenbergen, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096820 · Cited by 186

Nanotransducers in cellular redox signaling: modification of thiols by reactive oxygen and nitrogen species

Cooper, C. E., Patel, R. P., Brookes, P. S., & Darley-Usmar, V. M. (2002) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(02)02191-6 · Cited by 180

The Complex Interplay between Mitochondria, ROS and Entire Cellular Metabolism

Kuznetsov, A. V., Margreiter, R., Ausserlechner, M. J., & Hagenbuchner, J. (2022) · Antioxidants · doi:10.3390/antiox11101995 · Cited by 182

Mcl-1 promotes lung cancer cell migration by directly interacting with VDAC to increase mitochondrial Ca2+ uptake and reactive oxygen species generation

Huang, H., Shah, K., Bradbury, N. A., Li, C., & White, C. (2014) · Cell Death and Disease · doi:10.1038/cddis.2014.419 · Cited by 174

Marine invertebrate mitochondria and oxidative stress

Abele, D. (2006) · Frontiers in bioscience · doi:10.2741/2115 · Cited by 162

Mitochondria, nitric oxide, and cardiovascular dysfunction

Ramachandran, A., Levonen, A., Brookes, P. S., CEASER, E. K., Shiva, S., Barone, M. C., & Darley-Usmar, V. M. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01142-5 · Cited by 149

Oxidized LDL induces mitochondrially associated reactive oxygen/nitrogen species formation in endothelial cells

Żmijewski, J. W., Moellering, D. R., Goffe, C. L., Landar, A. L., Ramachandran, A., & Darley-Usmar, V. M. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00015.2005 · Cited by 149

Ketamine-Induced Neuronal Damage and Altered N-Methyl-d-Aspartate Receptor Function in Rat Primary Forebrain Culture

Liu, F., Patterson, T. A., Sadovova, N., Zhang, X., Liu, S., Zou, X., Hanig, J. P., Paule, M. G., Slikker, W., & Wang, C. (2012) · Toxicological Sciences · doi:10.1093/toxsci/kfs296 · Cited by 154

Role of Nitric Oxide in Neurodegeneration: Function, Regulation, and Inhibition

Tewari, D., Sah, A. N., Bawari, S., Nabavi, S. F., Dehpour, A. R., Shirooie, S., Braidy, N., Fiebich, B. L., Vacca, R. A., & Nabavi, S. M. (2020) · Current Neuropharmacology · doi:10.2174/1570159x18666200429001549 · Cited by 132

From Mitochondria to Disease: Role of the Renin-Angiotensin System

de Cavanagh, E. M. V., Inserra, F., Ferder, M., & Ferder, L. (2007) · American Journal of Nephrology · doi:10.1159/000107757 · Cited by 124

Renal mitochondrial dysfunction in spontaneously hypertensive rats is attenuated by losartan but not by amlodipine

de Cavanagh, E. M. V., Toblli, J. E., Ferder, L., Piotrkowski, B., Stella, I., & Inserra, F. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00615.2005 · Cited by 120

Control of Mitochondrial Respiration by NO., Effects of Low Oxygen and Respiratory State

Brookes, P. S., Kraus, D. W., Shiva, S., Doeller, J. E., Barone, M.-C., Patel, R. P., Lancaster, J. R., & Darley-Usmar, V. M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211784200 · Cited by 118

The role of iNOS in alcohol-dependent hepatotoxicity and mitochondrial dysfunction in mice

Venkatraman, A., Shiva, S., Wigley, A., Ulasova, E., Chhieng, D., Bailey, S. M., & Darley-Usmar, V. M. (2004) · Hepatology · doi:10.1002/hep.20326 · Cited by 117

Inorganic nitrite therapy: historical perspective and future directions

Kevil, C. G., Kolluru, G. K., Pattillo, C. B., & Giordano, T. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.04.042 · Cited by 113

Role of Endothelial Nitric Oxide Synthase in Diabetic Nephropathy: Lessons from Diabetic eNOS Knockout Mice

Takahashi, T., & Harris, R. C. (2014) · Journal of Diabetes Research · doi:10.1155/2014/590541 · Cited by 116

Estrogen, mitochondria, and growth of cancer and non-cancer cells.

Felty, Q. H., & Roy, D. (2005) · Journal of Carcinogenesis · doi:10.1186/1477-3163-4-1 · Cited by 123

Nitroxia: The pathological consequence of dysfunction in the nitric oxide–cytochrome c oxidase signaling pathway

Shiva, S., Oh, J.-Y., Landar, A. L., Ulasova, E., Venkatraman, A., Bailey, S. M., & Darley-Usmar, V. M. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.10.037 · Cited by 112

Cell signalling by oxidized lipids and the role of reactive oxygen species in the endothelium

Zmijewski, J. W., Landar, A., Watanabe, N., Dickinson, D. A., Noguchi, N., & Darley-Usmar, V. M. (2005) · Biochemical Society Transactions · doi:10.1042/bst20051385 · Cited by 112

Merkel cell carcinoma: combined surgery and radiation therapy.

Cotlar, A. M., Gates, J., & Gibbs, F. A. (1986) · PubMed · Cited by 106

Nitric oxide-induced persistent inhibition and nitrosylation of active site cysteine residues of mitochondrial cytochrome-c oxidase in lung endothelial cells

Zhang, J., Jin, B., Li, L., Block, E. R., & Patel, J. M. (2005) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00325.2004 · Cited by 102

Reactive oxygen species and α,β‐unsaturated aldehydes as second messengers in signal transduction

Forman, H. J. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05551.x · Cited by 96

Reversal of Cyanide Inhibition of Cytochrome c Oxidase by the Auxiliary Substrate Nitric Oxide

Pearce, L. L., Bominaar, E. L., Hill, B. C., & Peterson, J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m310359200 · Cited by 95

Low-Level Laser Effect on Proliferation, Migration, and Antiapoptosis of Mesenchymal Stem Cells

Yin, K., Zhu, R., Wang, S., & Zhao, R. C. (2017) · Stem Cells and Development · doi:10.1089/scd.2016.0332 · Cited by 92

Mitochondria as metabolizers and targets of nitrite

Shiva, S. (2010) · Nitric Oxide · doi:10.1016/j.niox.2009.09.002 · Cited by 87

Review of RyR1 pathway and associated pathomechanisms

Witherspoon, J. W., & Meilleur, K. G. (2016) · Acta Neuropathologica Communications · doi:10.1186/s40478-016-0392-6 · Cited by 94

Bioenergetic Differences in the Airway Epithelium of Lean Versus Obese Asthmatics Are Driven by Nitric Oxide and Reflected in Circulating Platelets

Winnica, D., Corey, C. G., Mullett, S. J., Reynolds, M. J., Hill, G., Wendell, S. L., Que, L. G., Holguín, F., & Shiva, S. (2019) · Antioxidants and Redox Signaling · doi:10.1089/ars.2018.7627 · Cited by 81

Interactions of Mitochondrial Thiols with Nitric Oxide

Costa, N. J., Dahm, C. C., Hurrell, F., Taylor, E. R., & Murphy, M. P. (2003) · Antioxidants and Redox Signaling · doi:10.1089/152308603322110878 · Cited by 77

Modulation of GSH levels in ABCC1 expressing tumor cells triggers apoptosis through oxidative stress

Laberge, R.-M., Karwatsky, J., Lincoln, M. C., Leimanis, M. L., & Georges, E. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.02.005 · Cited by 75

Nitric oxide and the respiratory enzyme

Brunori, M., Forte, E., Arese, M., Mastronicola, D., Giuffrè, A., & Sarti, P. (2006) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2006.05.011 · Cited by 77

Mitochondria-targeted agents: Future perspectives of mitochondrial pharmaceutics in cardiovascular diseases

Ajith, T. A. (2014) · World Journal of Cardiology · doi:10.4330/wjc.v6.i10.1091 · Cited by 73

Mitochondria-targeted heme oxygenase-1 decreases oxidative stress in renal epithelial cells

Bolisetty, S., Traylor, A., Zarjou, A., Johnson, M. S., Benavides, G. A., Ricart, K. C., Boddu, R., Moore, R. D., Landar, A. L., Barnes, S., et al. (2013) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00160.2013 · Cited by 68

Chronic exposure to nitric oxide alters the free iron pool in endothelial cells: Role of mitochondrial respiratory complexes and heat shock proteins

Ramachandran, A., CEASER, E. K., & Darley-Usmar, V. M. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0304653101 · Cited by 67

Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism

Wende, A. R., Young, M. E., Chatham, J. C., Zhang, J., Rajasekaran, N. S., & Darley-Usmar, V. M. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.05.022 · Cited by 66

Melatonin and Nitric Oxide: Two Required Antagonists for Mitochondrial Homeostasis

Acuña-Castroviejo, D., Escames, G., López, L. C., Hitos, A. B., & León, J. (2005) · Endocrine · doi:10.1385/endo:27:2:159 · Cited by 65

Thioredoxin reduces post‐ischemic myocardial apoptosis by reducing oxidative/nitrative stress

Tao, L., Gao, E., Hu, A., Coletti, C., Wang, Y., Christopher, T. A., Lopez, B. L., Koch, W. J., & L, X. (2006) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706853 · Cited by 64

Interactions between NO and O2 in the microcirculation: a mathematical analysis

Lamkin-Kennard, K. A., Buerk, D. G., & Jaron, D. (2004) · Microvascular Research · doi:10.1016/j.mvr.2004.03.001 · Cited by 64

Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats

Xin, H., Zhang, B., Wu, Z., Hang, X., Xu, W., Ni, W., Zhang, R., & Miao, X. (2014) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-014-2024-4 · Cited by 63

Mitochondrial Protection by PARP Inhibition

Gallyas, F., & Sümegi, B. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21082767 · Cited by 58

Mitochondrial Ca2+flux and respiratory enzyme activity decline are early events in cardiomyocyte response to H2O2

LONG, X. (2004) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2004.04.001 · Cited by 58

Keeping the heart in balance: the functional interactions of myoglobin with nitrogen oxides

Flögel, U., Fago, A., & Rassaf, T. (2010) · Journal of Experimental Biology · doi:10.1242/jeb.041681 · Cited by 57

Nitrative thioredoxin inactivation as a cause of enhanced myocardial ischemia/reperfusion injury in the aging heart

Zhang, H., Tao, L., Jiao, X., Gao, E., Lopez, B. L., Christopher, T. A., Koch, W. J., & Ma, X. L. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.03.016 · Cited by 56

Nitric Oxide Inactivation Mechanisms in the Brain: Role in Bioenergetics and Neurodegeneration

Santos, R. M., Lourenço, C. F., Ledo, A., Barbosa, R. M., & Laranjinha, J. A. N. (2012) · International Journal of Cell Biology · doi:10.1155/2012/391914 · Cited by 54

Nitric oxide and cell signaling; modulation of redox tone and protein modification

Landar, A. L., & Darley-Usmar, V. M. (2003) · Amino Acids · doi:10.1007/s00726-003-0019-7 · Cited by 50

Thioredoxin-1 attenuates post-ischemic neuronal apoptosis via reducing oxidative/nitrative stress

Ma, Y., Su, N., Chao, X. D., Zhang, Y. Q., Zhang, L., Han, F., Luo, P., Fei, Z., & Qu, Y. (2012) · Neurochemistry International · doi:10.1016/j.neuint.2012.01.029 · Cited by 49

Kinetic model of the inhibition of respiration by endogenous nitric oxide in intact cells

Aguirre, E., Rodríguez-Juárez, F., Bellelli, A., Gnaiger, E., & Cadenas, S. (2010) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2010.01.033 · Cited by 47

Competitive, reversible, physiological? Inhibition of mitochondrial cytochrome oxidase by nitric oxide

Cooper, C. (2003) · IUBMB Life · doi:10.1080/15216540310001628663 · Cited by 46

A highlight of myoglobin diversity: the nitrite reductase activity during myocardial ischemia–reperfusion

Hendgen-Cotta, U. B., Kelm, M., & Rassaf, T. (2010) · Nitric Oxide · doi:10.1016/j.niox.2009.10.003 · Cited by 46

Mitochondria and Nitric Oxide: Chemistry and Pathophysiology

Sarti, P., Arese, M., Forte, E., Giuffrè, A., & Mastronicola, D. (2011) · Advances in experimental medicine and biology · doi:10.1007/978-94-007-2869-1_4 · Cited by 46

The detection of the nitrite reductase and NO-generating properties of haemoglobin by mitochondrial inhibition

Shiva, S., Rassaf, T., Patel, R. P., & Gladwin, M. T. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq327 · Cited by 48

Kidney Mitochondrial Nitric Oxide Synthase

Boveris, A., Valdez, L. B., Álvarez, S., Zaobornyj, T., Boveris, A. D., & Navarro, A. (2003) · Antioxidants and Redox Signaling · doi:10.1089/152308603322110841 · Cited by 45

Red and near infra-red signaling: Hypothesis and perspectives

Kreslavski, V. D., Fomina, I. R., Los, D. A., Carpentier, R., Kuznetsov, V. V., & Allakhverdiev, S. I. (2012) · Journal of Photochemistry and Photobiology C Photochemistry Reviews · doi:10.1016/j.jphotochemrev.2012.01.002 · Cited by 44

Pollution induced nitrative stress and heat shock protein 70 overexpression in fish liver mitochondria

Padmini, E., Geetha, B., & Rani, M. U. (2008) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2008.09.038 · Cited by 46

Mitochondrial signals to nucleus regulate estrogen-induced cell growth

Felty, Q. H., & Roy, D. (2004) · Medical Hypotheses · doi:10.1016/j.mehy.2003.12.056 · Cited by 42

Redox signalling: from nitric oxide to oxidized lipids

Shiva, S., Moellering, D. R., Ramachandran, A., Levonen, A., Landar, A. L., Venkatraman, A., CEASER, E. K., Ulasova, E., Crawford, J. H., Brookes, P. S., et al. (2004) · Biochemical Society Symposia · doi:10.1042/bss0710107 · Cited by 41

Reperfusion Cardiac Injury: Receptors and the Signaling Mechanisms

Маслов, Л. Н., Popov, S. V., Mukhomedzyanov, А. V., Naryzhnaya, N. V., Воронков, Н. С., Ryabov, V. V., Boshchenko, A. A., Khaliulin, I., Prasad, N. R., Fu, F., et al. (2022) · Current Cardiology Reviews · doi:10.2174/1573403x18666220413121730 · Cited by 41

Reductive Gas-Phase Chemiluminescence and Flow Injection Analysis for Measurement of the Nitric Oxide Pool in Biological Matrices

Hendgen-Cotta, U. B., Grau, M., Rassaf, T., Gharini, P. P. R., Kelm, M., & Kleinbongard, P. (2008) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(08)01216-0 · Cited by 40

Preclinical Assessment of Ketamine

Wang, C., Liu, F., Patterson, T. A., Paule, M. G., & Slikker, W. (2013) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12079 · Cited by 38

A Novel Mitochondrial Signaling Pathway Activated by Visible‐to‐near Infrared Radiation ¶

Karu, T. I., Pyatibrat, L. V., & Afanasyeva, N. I. (2004) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2004.tb00097.x · Cited by 39

Roles of NADPH oxidase and mitochondria in flow‐induced vasodilation of human adipose arterioles: ROS ‐induced ROS release in coronary artery disease

Zinkevich, N. S., Fancher, I. S., Gutterman, D. D., & Phillips, S. A. (2017) · Microcirculation · doi:10.1111/micc.12380 · Cited by 37

Cardioprotective actions of nitrite therapy and dietary considerations

Nathan, S. B. (2009) · Frontiers in bioscience · doi:10.2741/3568 · Cited by 34

Measurement of mitochondrial respiratory thresholds and the control of respiration by nitric oxide

Brookes, P. S., Shiva, S., Patel, R. P., & Darley-Usmar, V. M. (2002) · Methods in Enzymology · doi:10.1016/s0076-6879(02)59194-1 · Cited by 33

Selenite Activates Caspase-Independent Necrotic Cell Death in Jurkat T Cells and J774.2 Macrophages by Affecting Mitochondrial Oxidant Generation

Shilo, S., & Tirosh, O. (2003) · Antioxidants and Redox Signaling · doi:10.1089/152308603322110850 · Cited by 33

Effects of α-mangostin on mitochondrial energetic metabolism

Abundis, E. M., Garcı́a, N., Correa, F., Hernández‐Reséndiz, S., Pedraza‐Chaverrí, J., & Zazueta, C. (2009) · Mitochondrion · doi:10.1016/j.mito.2009.12.140 · Cited by 32

Effects of oxidative challenge and calcium on ATP-levels in neuronal cells

Teepker, M., Anthes, N., Fischer, S., Krieg, J.-C., & Vedder, H. (2006) · NeuroToxicology · doi:10.1016/j.neuro.2006.06.001 · Cited by 32

The Adenosine A3 Receptor Agonist Cl-IB-MECA Induces Cell Death Through Ca2+/ROS-Dependent Down Regulation of ERK and Akt in A172 Human Glioma Cells

Kim, T. H., Kim, Y. K., & Woo, J. S. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0855-5 · Cited by 32

Cardioprotection by Sulfaphenazole, a Cytochrome P450 Inhibitor: Mitigation of Ischemia-Reperfusion Injury by Scavenging of Reactive Oxygen Species

Khan, M., Mohan, I. K., Kutala, V. K., Kumbala, D. R., & Kuppusamy, P. (2007) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.129486 · Cited by 32

Mitochondrial function and nitric oxide metabolism are modified by enalapril treatment in rat kidney

Piotrkowski, B., Fraga, C. G., & de Cavanagh, E. M. V. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00540.2006 · Cited by 30

Pathway of Programmed Cell Death and Oxidative Stress Induced by β-Hydroxybutyrate in Dairy Cow Abomasum Smooth Muscle Cells and in Mouse Gastric Smooth Muscle

Tian, W., Wei, T., Li, B., Wang, Z., Zhang, N., & Xie, G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096775 · Cited by 29

Relationship between intracellular Ca2+ and ROS during fluoride‐induced injury in SH‐SY5Y cells

Xu, Z., Xu, B., Xia, T., He, W., Gao, P., Guo, L., Wang, Z., Niu, Q., & Wang, A. (2011) · Environmental Toxicology · doi:10.1002/tox.20721 · Cited by 28

Down's syndrome astrocytes have greater antioxidant capacity than euploid astrocytes

Sebastià, J., Cristòfol, R. M., Pertusa, M., Vı́lchez, D., Torán, N., Barambio, S., Rodrı́guez-Farré, E., & Sanfeliu, C. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03686.x · Cited by 25

The Ligand Binding Battle at Cytochrome c Oxidase

Gladwin, M. T., & Shiva, S. (2009) · Circulation Research · doi:10.1161/circresaha.109.198911 · Cited by 25

The Nitrate–Nitrite–Nitric Oxide Pathway in Mammals

Lundberg, J. O., Weitzberg, E., Shiva, S., & Gladwin, M. T. (2011) · Humana Press eBooks · doi:10.1007/978-1-60761-616-0_3 · Cited by 26

Hydrogen Peroxide: The Good, The Bad, and The Ugly

Forman, H. J. (2008) · Springer eBooks · doi:10.1007/978-1-4020-8399-0_1 · Cited by 24

Mitochondria and Cancer

Owens, K. M., Modica-Napolitano, J. S., & Singh, K. K. (2008) · Springer eBooks · doi:10.1007/978-0-387-84835-8_1 · Cited by 21

Embryotrophic effects of ethylenediaminetetraacetic acid and hemoglobin on in vitro porcine embryos development

Kim, J. H., Lee, S. H., Kim, S., Jeong, Y. W., Koo, O. J., Hashem, M., Park, S. M., Lee, E. G., Hossein, M. S., Kang, S. K., et al. (2006) · Theriogenology · doi:10.1016/j.theriogenology.2005.12.008 · Cited by 20

The Intrinsic Antimicrobial Activity of Bamboo Salt against Salmonella enteritidis

Moon, J.-H., Shin, H. A., Rha, Y., & Om, A. (2009) · Molecular & Cellular Toxicology · Cited by 19

Ciglitazone induces apoptosis via activation of p38 MAPK and AIF nuclear translocation mediated by reactive oxygen species and Ca2+ in opossum kidney cells

Kwon, C. H., Park, J., Kim, T. H., Woo, J. S., & Kim, Y. K. (2008) · Toxicology · doi:10.1016/j.tox.2008.11.019 · Cited by 17

Mitochondria-Nucleus Interactions: Evidence for Mitochondrial Retrograde Communication in Plant Cells

Rhoads, D. M., & Vanlerberghe, G. C. (2004) · Advances in photosynthesis and respiration · doi:10.1007/978-1-4020-2400-9_5 · Cited by 16

In vitroeffect of hydrostatic pressure exposure on hydroxyl radical production in fish red muscle

Amérand, A., Vettier, A., Sebert, P., & Cann-Moisan, C. (2005) · Redox Report · doi:10.1179/135100005x21589 · Cited by 16

Control of the Nitric Oxide‐Cytochrome c Oxidase Signaling Pathway under Pathological and Physiological Conditions

Shiva, S. S., & Darley-Usmar, V. M. (2003) · IUBMB Life · doi:10.1080/152165430310001640489 · Cited by 27

Nitric oxide signaling gone awry

Landar, A. L., & Darley-Usmar, V. M. (2005) · Hepatology · doi:10.1002/hep.20699 · Cited by 3

Mitochondria: regulators of signal transduction by reactive oxygen and nitrogen species

Brookes, P. S., Levonen, A.-L., Shiva, S., Sarti, P., & Darley-Usmar, V. M. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00901-2 · Cited by 298

Nitric Oxide and Mitochondrial Signaling: From Physiology to Pathophysiology

Erusalimsky, J. D., & Moncada, S. (2007) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.107.151167 · Cited by 336

Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: Implications for oxygen sensing and hypoxic signaling in eukaryotes

Castello, P. R., David, P. S., McClure, T., Crook, Z., & Poyton, R. O. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.02.011 · Cited by 495