Plasma protein (albumin) catabolism by the tumor itself—implications for tumor metabolism and the genesis of cachexia

Cancer: Principles and Practice of Oncology.

(1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-9-819_4 · Cited by 8,524 · see citing works

Principles of biochemistry

(1978) · Biochemical Education · doi:10.1016/0307-4412(78)90049-3 · Cited by 5,073 · see citing works

The metabolism of tumors in the body

Warburg, O., Wind, F., & Negelein, E. (1927) · Journal of General Physiology · doi:10.1085/jgp.8.6.519 · Cited by 4,416 · see citing works

All About Albumin: Biochemistry, Genetics, and Medical Applications

Peters, T. (1995) · Thammasat University Digital Collections · Cited by 3,089 · see citing works

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules.

Rock, K. L., Gramm, C., Rothstein, L., Clark, K., Stein, R., Dick, L., Hwang, D., & Goldberg, A. L. (1994) · Cell · doi:10.1016/s0092-8674(94)90462-6 · Cited by 2,524 · see citing works

Serum Albumin

Peters, T. (1985) · Advances in protein chemistry · doi:10.1016/s0065-3233(08)60065-0 · Cited by 2,183 · see citing works

Lysosomes in biology and pathology

(1977) · Food and Cosmetics Toxicology · doi:10.1016/s0015-6264(77)80214-9 · Cited by 1,974 · see citing works

THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION

Hershko, A., & Ciechanover, A. J. (1992) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.61.070192.003553 · Cited by 1,419 · see citing works

Determinants of tumor blood flow: a review.

Jain, R. K. (1988) · PubMed · Cited by 1,364 · see citing works

Transport of molecules in the tumor interstitium: a review.

Jain, R. K. (1987) · PubMed · Cited by 1,357 · see citing works

Starvation in Man

Sherwood, L. M., Parris, E. E., & Cahill, G. F. (1970) · New England Journal of Medicine · doi:10.1056/nejm197003192821209 · Cited by 1,253 · see citing works

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.

Reitzer, L. J., Wice, B. M., & Kennell, D. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)30124-2 · Cited by 1,240 · see citing works

Virus-associated hemophagocytic syndromeA benign histiocytic proliferation distinct from malignant histiocytosis

Risdall, R. J., McKenna, R. W., Nesbit, M. E., Krivit, W. A., Balfour, H. H., Simmons, R. L., & Brunning, R. D. (1979) · Cancer · doi:10.1002/1097-0142(197909)44:3 · Cited by 1,037 · see citing works

Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements.

Vaupel, P. W., Schlenger, K., Knoop, C., & Höckel, M. (1991) · PubMed · Cited by 952 · see citing works

Principles of biochemistry

(1994) · International Journal of Biochemistry · doi:10.1016/0020-711x(94)90020-5 · Cited by 941 · see citing works

Ubiquitin, proteasomes, and the regulation of intracellular protein degradation

Hochstrasser, M. (1995) · Current Opinion in Cell Biology · doi:10.1016/0955-0674(95)80031-x · Cited by 895 · see citing works

Untitled work

(1990) · PubMed · Cited by 757 · see citing works

Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure.

Jain, R. K., & Baxter, L. T. (1988) · PubMed · Cited by 710 · see citing works

Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors.

Jain, R. K. (1990) · PubMed · Cited by 574 · see citing works

Delivery of Novel Therapeutic Agents in Tumors: Physiological Barriers and Strategies

Jain, R. K. (1989) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/81.8.570 · Cited by 564 · see citing works

Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse.

Boucher, Y., & Jain, R. K. (1992) · PubMed · Cited by 510 · see citing works

Microvascular architecture in a mammary carcinoma: branching patterns and vessel dimensions.

Less, J. R., Skalak, T. C., Sevick, E., & Jain, R. K. (1991) · PubMed · Cited by 508 · see citing works

Vascular and interstitial barriers to delivery of therapeutic agents in tumors

Jain, R. K. (1990) · Cancer and Metastasis Reviews · doi:10.1007/bf00046364 · Cited by 493 · see citing works

Structure and ligand binding properties of human serum albumin.

Kragh‐Hansen, U. (1990) · PubMed · Cited by 454 · see citing works

Recombinant human interleukin‐6 (IL‐6/BSF‐2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes

Castell, J. V., Gómez-Lechón, M. J., David, M., Hirano, T., Kishimoto, T., & Heinrich, P. C. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)80766-x · Cited by 452 · see citing works

Serum albumin

Rothschild, M. A., Oratz, M., & Schreiber, S. S. (1988) · Hepatology · doi:10.1002/hep.1840080234 · Cited by 439 · see citing works

Pressure Sores Among Hospitalized Patients

Allman, R. M., Laprade, C. A., Noel, L. B., et al. (1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-105-3-337 · Cited by 423 · see citing works

Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice.

Tsujinaka, T., Fujita, J., Ebisui, C., Yano, M., Kominami, E., Suzuki, K., Tanaka, K., Katsume, A., Ohsugi, Y., Shiozaki, H., et al. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118398 · Cited by 421 · see citing works

The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme.

Moreadith, R. W., & Lehninger, A. L. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)82128-0 · Cited by 415 · see citing works

Proteases and protein degradation inEscherichia coli

Maurizi, M. R. (1992) · Cellular and Molecular Life Sciences · doi:10.1007/bf01923511 · Cited by 406 · see citing works

Metabolic acidosis stimulates muscle protein degradation by activating the adenosine triphosphate-dependent pathway involving ubiquitin and proteasomes.

Mitch, W. E., Medina, R., Grieber, S., May, R. C., England, B. K., Price, S. R., Bailey, J. L., & Goldberg, A. L. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117208 · Cited by 405 · see citing works

Serum alpha-fetoprotein, albumin, and gamma-G-globulin in the human conceptus.

Gitlin, D., & Boesman, M. I. (1966) · Journal of Clinical Investigation · doi:10.1172/jci105486 · Cited by 404 · see citing works

Proteasomes: destruction as a programme

Hilt, W., & Wolf, D. H. (1996) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(96)10012-8 · Cited by 373 · see citing works

Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting

Wing, S. S., & Goldberg, A. L. (1993) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1993.264.4.e668 · Cited by 345 · see citing works

The proteasome (multicatalytic protease) is a component of the 1500-kDa proteolytic complex which degrades ubiquitin-conjugated proteins.

Driscoll, J. J., & Goldberg, A. L. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)34041-4 · Cited by 325 · see citing works

A radioiodinated, intracellularly trapped ligand for determining the sites of plasma protein degradation in vivo

Pittman, R. C., Carew, T. E., Glass, C. K., Green, S. R., Taylor, C. A., & Attie, A. (1983) · Biochemical Journal · doi:10.1042/bj2120791 · Cited by 318 · see citing works

Proteases as prognostic markers in cancer.

Duffy, M. J. (1996) · PubMed · Cited by 317 · see citing works

Albumin Synthesis

Rothschild, M. A., Oratz, M., & Schreiber, S. S. (1972) · New England Journal of Medicine · doi:10.1056/nejm197204062861404 · Cited by 314 · see citing works

Proteasomes: protein degradation machines of the cell

Peters, J. (1994) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(94)90115-5 · Cited by 311 · see citing works

Role of different proteolytic systems in the degradation of muscle proteins during denervation atrophy.

Furuno, K., Goodman, M. N., & Goldberg, A. L. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38923-9 · Cited by 300 · see citing works

Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy

Medina, R., Wing, S. S., & Goldberg, A. L. (1995) · Biochemical Journal · doi:10.1042/bj3070631 · Cited by 294 · see citing works

Uncomplicated starvation versus cancer cachexia.

Brennan, M. F. (1977) · PubMed · Cited by 292 · see citing works

Uptake of Protein by Mammalian Cells: An Underdeveloped Area

Ryser, H. J. ‐. (1968) · Science · doi:10.1126/science.159.3813.390 · Cited by 288 · see citing works

Sites of Serum α-Fetoprotein Synthesis in the Human and in the Rat*

Gitlin, D., & Boesman, M. I. (1967) · Journal of Clinical Investigation · doi:10.1172/jci105590 · Cited by 284 · see citing works

Reviews: Role of Albumin in Human Physiology and Pathophysiology

Doweiko, J. P., & Nompleggi, D. J. (1991) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607191015002207 · Cited by 281 · see citing works

Synthesis of Serum Albumin, Prealbumin, α-Foetoprotein, α1-Antitrypsin and Transferrin by the Human Yolk Sac

Gitlin, D., & Perricelli, A. (1970) · Nature · doi:10.1038/228995a0 · Cited by 277 · see citing works

Albumin-Deficient Rat Mutant

Nagase, S., Shimamune, K., & Shumiya, S. (1979) · Science · doi:10.1126/science.451621 · Cited by 277 · see citing works

Activation of the ATP-ubiquitin-proteasome pathway in skeletal muscle of cachectic rats bearing a hepatoma.

Baracos, V., DeVivo, C., Hoyle, D., & Goldberg, A. (1995) · American Journal of Physiology · doi:10.1152/ajpendo.1995.268.5.e996 · Cited by 275 · see citing works

MEMBRANE PARTITIONING DURING CELL DIVISION

Warren, G. (1993) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.62.070193.001543 · Cited by 271 · see citing works

Transcytosis of albumin in capillary endothelium.

Milici, A. J., Watrous, N. E., Stukenbrok, H., & Palade, G. E. (1987) · The Journal of Cell Biology · doi:10.1083/jcb.105.6.2603 · Cited by 269 · see citing works

Deviant energetic metabolism of glycolytic cancer cells

Baggetto, L. G. (1992) · Biochimie · doi:10.1016/0300-9084(92)90016-8 · Cited by 268 · see citing works

The cancer anorexia-cachexia syndrome.

Nelson, K. A., Walsh, D., & Sheehan, F. (1994) · Journal of Clinical Oncology · doi:10.1200/jco.1994.12.1.213 · Cited by 265 · see citing works

Cancer cachexia

Kern, K. A., & Norton, J. (1988) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607188012003286 · Cited by 265 · see citing works

Cachexia, the Metabolic Component of Neoplastic Diseases

Costa, G. (2015) · Progress in tumor research · doi:10.1159/000385967 · Cited by 259 · see citing works

Reviews: The Role of Albumin in Human Physiology and Pathophysiology, Part III: Albumin and Disease States

Doweiko, J. P., & Nompleggi, D. J. (1991) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607191015004476 · Cited by 258 · see citing works

über den Stoffwechsel der Carcinomzelle

Warburg, O. H. (1925) · Journal of Molecular Medicine · doi:10.1007/bf01726151 · Cited by 257 · see citing works

Therapeutic attack of hypoxic cells of solid tumors: presidential address.

Sartorelli, A. C. (1988) · PubMed · Cited by 255 · see citing works

Role of endogenous tumor necrosis factor alpha and interleukin 1 for experimental tumor growth and the development of cancer cachexia.

Gélin, J., Moldawer, L. L., Lönnroth, C., Sherry, B. A., Chizzonite, R., & Lundholm, K. (1991) · PubMed · Cited by 251 · see citing works

Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids.

Tiao, G. M., Fagan, J. M., Roegner, V., Lieberman, M. A., Wang, J. J., Fischer, J. E., & Hasselgren, P. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118421 · Cited by 248 · see citing works

Untitled work

(1992) · PubMed · Cited by 247 · see citing works

A comparative study of central nervous system irradiation and intensive chemotherapy early in remission of childhood acute lymphocytic leukemia

Aur, R. J. A., Simone, J. V., Hustu, H. O., & Verzosa, M. S. (1972) · Cancer · doi:10.1002/1097-0142(197202)29:2 · Cited by 241 · see citing works

Proteases and proteolysis in the lysosome

Bohley, P., & Seglen, P. O. (1992) · Cellular and Molecular Life Sciences · doi:10.1007/bf01923508 · Cited by 236 · see citing works

Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca2+ -activated, and ubiquitin-proteasome proteolytic pathways.

Voisin, L., Breuillé, D., Combaret, L., Pouyet, C., Taillandier, D., AUROUSSEAU, E., Obled, C., & Attaix, D. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118586 · Cited by 225 · see citing works

Increase in ubiquitin-protein conjugates concomitant with the increase in proteolysis in rat skeletal muscle during starvation and atrophy denervation

Wing, S. S., Haas, A. L., & Goldberg, A. L. (1995) · Biochemical Journal · doi:10.1042/bj3070639 · Cited by 222 · see citing works

Direct access to serum macromolecules by intraerythrocytic malaria parasites

Pouvelle, B., Spiegel, R. J., Hsiao, L. L., Howard, R. J., Morris, R., Thomas, A. P., & Taraschi, T. F. (1991) · Nature · doi:10.1038/353073a0 · Cited by 218 · see citing works

Increased ATP-ubiquitin-dependent proteolysis in skeletal muscles of tumor-bearing rats.

Temparis, S., Asensi, M., Taillandier, D., AUROUSSEAU, E., Larbaud, D., Obled, A., Béchet, D., Ferrara, M., Estrela, J. M., & Attaix, D. (1994) · PubMed · Cited by 214 · see citing works

DIAGNOSTIC INDEX FOR PREMYXŒDEMA

Ikram, H., Banim, S. O., & Fowler, P. B. S. (1974) · The Lancet · doi:10.1016/s0140-6736(74)92533-1 · Cited by 211 · see citing works

THE REGULATION OF PINOCYTOSIS IN MOUSE MACROPHAGES

Cohn, Z. A., & Parks, E. (1967) · The Journal of Experimental Medicine · doi:10.1084/jem.125.2.213 · Cited by 207 · see citing works

Endocytosis: what goes in and how?

Watts, C. K. W., & Marsh, M. (1992) · Journal of Cell Science · doi:10.1242/jcs.103.1.1a · Cited by 180 · see citing works

Implications of Interferon-Induced Tryptophan Catabolism in Cancer, Autoimmune Diseases and Aids

Brown, R. R., Ozaki, Y., Datta, S. P., Borden, E. C., Sondel, P. M., & Malone, D. G. (1991) · Advances in experimental medicine and biology · doi:10.1007/978-1-4684-5952-4_39 · Cited by 174 · see citing works

EFFECT OF HYPOPROTEINEMIA ON WOUND DISRUPTION

THOMPSON, W. D. (1938) · Archives of Surgery · doi:10.1001/archsurg.1938.01190210129008 · Cited by 171 · see citing works

THE UPTAKE AND DIGESTION OF IODINATED HUMAN SERUM ALBUMIN BY MACROPHAGES IN VITRO

Ehrenreich, B. A., & Cohn, Z. A. (1967) · The Journal of Experimental Medicine · doi:10.1084/jem.126.5.941 · Cited by 170 · see citing works

Substrate balances across colonic carcinomas in humans.

Holm, E., Hagmüller, E., Staedt, U., Schlickeiser, G., Günther, H.-J., Leweling, H., TOKUS, M., & Kollmar, H. B. (1995) · PubMed · Cited by 169 · see citing works

Intracellular trafficking and the parasitophorous vacuole of Leishmania mexicana-infected macrophages

Russell, D. G., Xu, S., & Chakraborty, P. (1992) · Journal of Cell Science · doi:10.1242/jcs.103.4.1193 · Cited by 169 · see citing works

Glutamine nutrition and metabolism: Where do we go from here?

Neu, J., Shenoy, V. B., & Chakrabarti, R. (1996) · The FASEB Journal · doi:10.1096/fasebj.10.8.8666159 · Cited by 165 · see citing works

The mechanisms and treatment of weight loss in cancer

Fearon, K. C. H. (1992) · Proceedings of The Nutrition Society · doi:10.1079/pns19920036 · Cited by 165 · see citing works

CANCER CACHEXIA AND PROTEIN METABOLISM

Jeevanandam, M., Lowry, S., Horowitz, G. D., et al. (1984) · The Lancet · doi:10.1016/s0140-6736(84)91929-9 · Cited by 162 · see citing works

The turnover of amniotic fluid protein in the human conceptus

Gitlin, D., Kumate, J., Morales, C. R., et al. (1972) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(72)90632-1 · Cited by 155 · see citing works

Tumor necrosis factor-alpha inhibits albumin gene expression in a murine model of cachexia.

Brenner, D. A., Buck, M., Feitelberg, S. P., & Chojkier, M. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114419 · Cited by 155 · see citing works

Metabolic Approaches to Cancer Cachexia

Lawson, D. H., Richmond, A. J., Nixon, D. W., et al. (1982) · Annual Review of Nutrition · doi:10.1146/annurev.nu.02.070182.001425 · Cited by 155 · see citing works

The metabolic events of starvation

Saudek, C. D., & Felig, P. (1976) · The American Journal of Medicine · doi:10.1016/0002-9343(76)90540-4 · Cited by 153 · see citing works

Amino acid, glucose, and lactic acid utilization in vivo by rat tumors.

Sauer, L. A., Stayman, J. W., & Dauchy, R. T. (1982) · PubMed · Cited by 152 · see citing works

Placental transfer of proteins in human gestation

Dancis, J., Lind, J., Oratz, M., et al. (1961) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(16)36111-7 · Cited by 137 · see citing works

The role of cathepsin D in the invasiveness of human breast cancer cells.

Johnson, M. D., Torri, J. A., Lippman, M. E., et al. (1993) · PubMed · Cited by 134 · see citing works

Amino Acid Regulation of Albumin Synthesis

Rothschild, M. A., Oratz, M., Mongelli, J., et al. (1969) · Journal of Nutrition · doi:10.1093/jn/98.4.395 · Cited by 133 · see citing works

Uptake of protein from solution by Amoeba proteus

Schumaker, V. N. (1958) · Experimental Cell Research · doi:10.1016/0014-4827(58)90033-8 · Cited by 131 · see citing works

Skeletal muscle and liver contain a soluble ATP + ubiquitin-dependent proteolytic system

Fagan, J. M., Waxman, L., & Goldberg, A. L. (1987) · Biochemical Journal · doi:10.1042/bj2430335 · Cited by 131 · see citing works

Tumor Necrosis Factor Not Detectable in Patients With Clinical Cancer Cachexia

Socher, S. H., Martínez, D., Craig, J. B., et al. (1988) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/80.8.595 · Cited by 130 · see citing works

Glucose uptake, lactate release, ketone body turnover, metabolic micromilieu, and pH distributions in human breast cancer xenografts in nude rats.

Kallinowski, F., Vaupel, P. W., Runkel, S., Berg, G., Fortmeyer, H. P., Baessler, K. H., Wagner, K., Mueller‐Klieser, W., & Walenta, S. (1988) · PubMed · Cited by 128 · see citing works

A comparative study of the influence of malignant tumor on host metabolism in mice and man.Evaluation of an experimental model

Lundholm, K., Edström, S., Ekman, L. G., Karlberg, I. H., Bylund, A., & Scherstén, T. (1978) · Cancer · doi:10.1002/1097-0142(197808)42:2 · Cited by 127 · see citing works

The price of liberty.

Leys, D., Penrose, M., Hodgson, H., et al. (1980) · PubMed · Cited by 122 · see citing works

Parabiotic transfer of cancer anorexia/cachexia in male rats.

Norton, J. A., Moley, J. F., Green, M. V., Carson, R. E., & Morrison, S. D. (1985) · PubMed · Cited by 122 · see citing works

Activation of the ubiquitin-ATP-dependent proteolytic system in skeletal muscle during fasting and denervation atrophy.

Medina, R., Wing, S. S., Haas, A., & Goldberg, A. L. (1991) · PubMed · Cited by 119 · see citing works

Enzymatic Synthesis of the Methyl Group of Methionine

Hatch, F. T., Larrabee, A. R., Cathou, R. E., et al. (1961) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64248-6 · Cited by 118 · see citing works

Overexpression and localization of cathepsin B during the progression of human gliomas

Sivaparvathi, M., Sawaya, R. A., Wang, S. W., et al. (1995) · Clinical & Experimental Metastasis · doi:10.1007/bf00144018 · Cited by 115 · see citing works

Protein transfer in tumor-bearing rats.

Babson, A. L., & Winnick, T. (1954) · PubMed · Cited by 112 · see citing works

The transport systems of mammalian lysosomes

Pisoni, R. L., & Thoene, J. G. (1991) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(91)90002-e · Cited by 112 · see citing works

Plasma Protein Synthesis in the Human Fetus and Placenta1

Dancis, J., Braverman, N., & Lind, J. (1957) · Journal of Clinical Investigation · doi:10.1172/jci103436 · Cited by 111 · see citing works

The Role of Cytokines in Cancer Cachexia

Moldawer, L. L., Rogy, M. A., & Lowry, S. F. (1992) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/014860719201600602 · Cited by 109 · see citing works

The antimalarial action of desferal involves a direct access route to erythrocytic (Plasmodium falciparum) parasites.

Loyevsky, M., Lytton, S. D., Mester, B., Libman, J., Shanzer, A., & Cabantchik, Z. I. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116174 · Cited by 108 · see citing works

The roles of gamma-interferon and tumor necrosis factor alpha in an experimental rat model of cancer cachexia.

Hn, L., Doherty, G. M., Fraker, D. L., Buresh, C. M., & Norton, J. A. (1991) · PubMed · Cited by 108 · see citing works

Stage-specific increases in cathepsin B messenger RNA content in human colorectal carcinoma.

Murnane, M. J., Sheahan, K. D., Özdemirli, M., & Shuja, S. (1991) · PubMed · Cited by 106 · see citing works

Muscle wasting associated with cancer cachexia is linked to an important activation of the atp‐dependent ubiquitin‐mediated proteolysis

Llovera, M., Garcia‐Martínez, C., Agell, N., et al. (1995) · International Journal of Cancer · doi:10.1002/ijc.2910610123 · Cited by 103 · see citing works

Albumin Synthesis

Rothschild, M. A., Oratz, M., & Schreiber, S. S. (1972) · New England Journal of Medicine · doi:10.1056/nejm197204132861505 · Cited by 103 · see citing works

The metabolic environment of cancer

Argilés, J. M. A., & Azcón‐Bieto, J. (1988) · Molecular and Cellular Biochemistry · doi:10.1007/bf00225648 · Cited by 100 · see citing works

Measurement of albumin synthesis in humans: a new approach employing stable isotopes

Ballmer, P. E., McNurlan, M. A., Milne, E., Heys, S. D., Buchan, V., Calder, A. G., & Garlick, P. J. (1990) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1990.259.6.e797 · Cited by 100 · see citing works

Burn injury stimulates multiple proteolytic pathways in skeletal muscle, including the ubiquitin-energy-dependent pathway.

Fang, C., Tiao, G. M., James, H. J., Ogle, C., Fischer, J. E., & Hasselgren, P. (1995) · PubMed · Cited by 100 · see citing works

Cytokines and Their Role in the Pathophysiology of Cancer Cachexia

McNamara, M. J., Alexander, H. R., & Norton, J. A. (1992) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/014860719201600603 · Cited by 98 · see citing works

Intracellular catabolism of radiolabeled anti-mu antibodies by malignant B-cells.

Geissler, F. T., Anderson, S. K., Venkatesan, P., et al. (1992) · PubMed · Cited by 98 · see citing works

PINOCYTOSIS IN ACANTHAMOEBA CASTELLANII

Bowers, B., & Olszewski, T. E. (1972) · The Journal of Cell Biology · doi:10.1083/jcb.53.3.681 · Cited by 98 · see citing works

Lysosomal Proteases Cathepsins D, B, H, L and Their Inhibitors Stefins A and B in Head and Neck Cancer

Kos, J., Šmid, A., Krašovec, M., et al. (1995) · Biological Chemistry Hoppe-Seyler · doi:10.1515/bchm3.1995.376.7.401 · Cited by 95 · see citing works

Pathophysiology of cancer cachexia: current understanding and areas for future research.

DeWys, W. D. (1982) · PubMed · Cited by 94 · see citing works

Tumour necrosis factor and cachexia: a current perspective

Espat, N. J., Copeland, E. M., & Moldawer, L. L. (1994) · Surgical Oncology · doi:10.1016/0960-7404(94)90027-2 · Cited by 90 · see citing works

Blood Flow, Oxygen Consumption and Tissue Oxygenation of Human Tumors

Vaupel, P. W., Kallinowski, F., & Okunieff, P. G. (1990) · Advances in experimental medicine and biology · doi:10.1007/978-1-4684-8181-5_103 · Cited by 87 · see citing works

Metabolic Imaging in Microregions of Tumors and Normal Tissues With Bioluminescence and Photon Counting

Mueller-Klieser, W., Walenta, S., Paschen, W., et al. (1988) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/80.11.842 · Cited by 82 · see citing works

Radioiodination of proteins and lipoproteins using N-bromosuccinimide as oxidizing agent

Sinn, H. J., Schrenk, H. H., Friedrich, E. A., et al. (1988) · Analytical Biochemistry · doi:10.1016/0003-2697(88)90107-8 · Cited by 80 · see citing works

Growth of carcinoma implants in fed and fasted rats.

LePage, G. A., POTTER, V. R., Busch, H., Heidelberger, C., & Hurlbert, R. B. (1952) · PubMed · Cited by 79 · see citing works

Measurement of capillary filtration coefficient in a solid tumor.

Sevick, E., & Jain, R. K. (1991) · PubMed · Cited by 79 · see citing works

Multiple binding of type 3 streptococcal M protein to human fibrinogen, albumin and fibronectin

Schmidt, K., Mann, K., Cooney, J. C., & hler, W. K. ̄. ⁄. (1993) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.1993.tb00392.x · Cited by 79 · see citing works

Sialic acid storage diseases. A multiple lysosomal transport defect for acidic monosaccharides.

Mancini, G. M. S., Beerens, C. E. M. T., Aula, P., et al. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115136 · Cited by 78 · see citing works

Role of thiols, pH and cathepsin D in the lysosomal catabolism of serum albumin

Mego, J. L. (1984) · Biochemical Journal · doi:10.1042/bj2180775 · Cited by 76 · see citing works

Pinocytotic uptake of fluorescein-labelled proteins by various tissue cells

Holter, H., & Holtzer, H. (1959) · Experimental Cell Research · doi:10.1016/0014-4827(59)90033-3 · Cited by 76 · see citing works

Establishment and characterization of cachexia‐inducing and ‐non‐inducing clones of murine colon 26 carcinoma

Fujimoto-Ouchi, K., Tamura, S., Mori, K., Tanaka, Y., & Ishitsuka, H. (1995) · International Journal of Cancer · doi:10.1002/ijc.2910610416 · Cited by 76 · see citing works

Tumor blood flow: The principal modulator of oxidative and glycolytic metabolism, and of the metabolic micromilieu of human tumor xenografts in vivo

Kallinowski, F., Schlenger, K., Kloes, M., et al. (1989) · International Journal of Cancer · doi:10.1002/ijc.2910440214 · Cited by 75 · see citing works

Post‐transcriptional control of negative acute phase genes by transforming growth factor beta.

Morrone, G., Cortese, R., & Sorrentino, V. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08553.x · Cited by 74 · see citing works

Metabolic effects of cancer

Douglas, R. G., & Shaw, J. H. F. (1990) · British journal of surgery · doi:10.1002/bjs.1800770305 · Cited by 71 · see citing works

Recent developments in the radiolabeling of antibodies with iodine, indium, and technetium

Hnatowich, D. J. (1990) · Seminars in Nuclear Medicine · doi:10.1016/s0001-2998(05)80178-3 · Cited by 71 · see citing works

Plasma and CSF tryptophan in cancer anorexia

Cangiano, C., Cascino, A., Ceci, F., Laviano, A., Mulieri, M., Muscaritoli, M., & Fanelli, F. R. (1990) · Journal of Neural Transmission · doi:10.1007/bf01245044 · Cited by 71 · see citing works

Cathepsin D maturation and its stimulatory effect on metastasis are prevented by addition of KDEL retention signal.

Liaudet, E., Garcia, M., & Rochefort, H. (1994) · PubMed · Cited by 71 · see citing works

Plasma tryptophan and anorexia in human cancer

Fanelli, F. R., Cangiano, C., Ceci, F., Cellerino, R., Franchi, F., Menichetti, E., Muscaritoli, M., & Cascino, A. (1986) · European Journal of Cancer and Clinical Oncology · doi:10.1016/0277-5379(86)90346-9 · Cited by 70 · see citing works

Über einen Fall von kompletter Analbuminaemie ohne wesentliche klinische Krankheitszeichen

Bennhold, H., Peters, H., & Roth, E. (1954) · Verhandlungen der Deutschen Gesellschaft für Innere Medizin · doi:10.1007/978-3-642-53819-3_139 · Cited by 70 · see citing works

Identification of the sites of IgG catabolism in the rat

Henderson, L. A., Baynes, J., & Thorpe, S. R. (1982) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(82)90272-7 · Cited by 69 · see citing works

Design of compounds having an enhanced tumour uptake, using serum albumin as a carrier. Part I

Sinn, H., Schrenk, H. H., Friedrich, E. A., et al. (1990) · International Journal of Radiation Applications and Instrumentation Part B Nuclear Medicine and Biology · doi:10.1016/0883-2897(90)90031-u · Cited by 68 · see citing works

Comparison of pinocytosis and phagocytosis in Acanthamoeba castellanii

Bowers, B. (1977) · Experimental Cell Research · doi:10.1016/0014-4827(77)90307-x · Cited by 67 · see citing works

Lysosomes, Lysosomal Enzymes, and Cancer

Boyer, M. J., & Tannock, I. F. (1992) · Advances in cancer research · doi:10.1016/s0065-230x(08)60828-3 · Cited by 66 · see citing works

Effects of radiolabeling monoclonal antibodies with a residualizing iodine radiolabel on the accretion of radioisotope in tumors.

Stein, R., Goldenberg, D. M., Thorpe, S. R., et al. (1995) · PubMed · Cited by 65 · see citing works

Cathepsins B, H and L in human breast carcinoma.

Gabrijelčič, D., Svetic, B., Spaic, D., et al. (1992) · PubMed · Cited by 65 · see citing works

Blood flow and venous pH of tissue-isolated Walker 256 carcinoma during hyperglycemia.

Sevick, E., & Jain, R. K. (1988) · PubMed · Cited by 64 · see citing works

Ubiquitin Gene Expression in Skeletal Muscle Is Increased During Sepsis: Involvement of TNF-α but Not IL-1

Garcia‐Martínez, C., Llovera, M., Agell, N., López-Soriano, F. J., & Argilés, J. M. A. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.2848 · Cited by 64 · see citing works

Cancer cachexia

Norton, J. A., Peacock, J. L., Morrison, S. D., & Popp, M. B. (1987) · Critical Reviews in Oncology/Hematology · doi:10.1016/s1040-8428(87)80003-3 · Cited by 64 · see citing works

Autoradiographic evaluation of the intra-tumoral distribution of 2-deoxy-D-glucose and monoclonal antibodies in xenografts of human ovarian adenocarcinoma.

Brown, R. S., Fisher, S. J., & Wahl, R. L. (1993) · PubMed · Cited by 60 · see citing works

Suppression of muscle protein turnover and amino acid degradation by dietary protein deficiency

Tawa, N. E., & Goldberg, A. L. (1992) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1992.263.2.e317 · Cited by 59 · see citing works

A nucleotide insertion and frameshift cause analbuminemia in an Italian family.

Watkins, S., Madison, J., Galliano, M., et al. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.6.2275 · Cited by 59 · see citing works

Identification of metabolites of 111In-diethylenetriaminepentaacetic acid-monoclonal antibodies and antibody fragments in vivo.

Rogers, B. E., Franano, F. N., Duncan, J. R., et al. (1995) · PubMed · Cited by 58 · see citing works

THE MEASUREMENT OF I131-SERUM ALBUMIN UPTAKE BY TUMOR CELLS IN TISSUE CULTURE.

Ryser, H. J. ‐. (1963) · PubMed · Cited by 58 · see citing works

Cancer cachexia

Tisdale, M. (1991) · British Journal of Cancer · doi:10.1038/bjc.1991.80 · Cited by 57 · see citing works

Protein turnover in the human fetus studied at term using stable isotope tracer amino acids

CHIEN, P. F. W., Smith, K., Watt, P., et al. (1993) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1993.265.1.e31 · Cited by 56 · see citing works

The design and application of residualizing labels for studies of protein catabolism

Thorpe, S. R., Baynes, J., & Chroneos, Z. C. (1993) · The FASEB Journal · doi:10.1096/fasebj.7.5.8462781 · Cited by 55 · see citing works

Interstitial Fluid Concentrations of Albumin and Immunoglobulin G in Normal Men

Poulsen, H. L. (1974) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365517409050824 · Cited by 55 · see citing works

Bioenergetics of tumor cells: Glutamine metabolism in tumor cell mitochondria

Matsuno, T. (1987) · International Journal of Biochemistry · doi:10.1016/0020-711x(87)90002-4 · Cited by 54 · see citing works

Culture media for human cells?RPMI 1603, RPMI 1634, RPMI 1640 and GEM 1717

Moore, G. E., & Woods, L. K. (1977) · Methods in Cell Science · doi:10.1007/bf00918753 · Cited by 52 · see citing works

The Utilization of Proteins by Cultured Human Cells

Eagle, H., & Piez, K. A. (1960) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69485-2 · Cited by 51 · see citing works

Interstitial Fluid Concentrations of Albumin and Immunoglobulin G in Normal Men

Poulsen, H. L. (1974) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365517409050824 · Cited by 50 · see citing works

Anorexia and cancer in animals and man

Garattini, S. K., Bizzi, A., Donelli, M. G., GUAITANI, A., SAMANIN, R., & Spreafico, F. (1980) · Cancer Treatment Reviews · doi:10.1016/s0305-7372(80)80027-2 · Cited by 49 · see citing works

Protein Content in Lymph and Edema Fluids in Congestive Heart Failure

Witte, C. L., Witte, M. H., Dumont, A. E., et al. (1969) · Circulation · doi:10.1161/01.cir.40.5.623 · Cited by 49 · see citing works

Mechanism of Early Tumor Anorexia

Muscaritoli, M., Meguid, M. M., Beverly, J. L., et al. (1996) · Journal of Surgical Research · doi:10.1006/jsre.1996.0064 · Cited by 49 · see citing works

Design of compounds having enhanced tumour uptake, using serum albumin as a carrier—part II. In vivo studies

Schilling, U., Friedrich, E. A., Sinn, H., et al. (1992) · International Journal of Radiation Applications and Instrumentation Part B Nuclear Medicine and Biology · doi:10.1016/0883-2897(92)90103-6 · Cited by 48 · see citing works

The Early Cancer Anorexia Paradigm: Changes in Plasma Free Tryptophan and Feeding Indexes

Meguid, M. M., Muscaritoli, M., Beverly, J. L., et al. (1992) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/014860719201600604 · Cited by 48 · see citing works

Gluconeogenesis in the Tumor-Influenced Rat Hepatocyte: Importance of Tumor Burden, Lactate, Insulin, and Glucagon

Inculet, R., Peacock, J. L., Gorschboth, C. M., & Norton, J. A. (1987) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/79.5.1039 · Cited by 47 · see citing works

Uptake of Proteins by Malignant Cells

GHOSE, T., Nairn, R. C., & Fothergill, J. E. (1962) · Nature · doi:10.1038/1961108b0 · Cited by 46 · see citing works

Studies on the metabolism of plasma proteins in tumorbearing rats.

Busch, H., & Greene, H. S. N. (1955) · PubMed · Cited by 45 · see citing works

Identification of fibroblasts as a major site of albumin catabolism in peripheral tissues.

Strobel, J. L., Cady, S. G., Borg, T. K., et al. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)57500-7 · Cited by 45 · see citing works

[3H]Raffinose, a novel radioactive label for determining organ sites of catabolism of proteins in the circulation.

Zile, J. V., Henderson, L. A., Baynes, J., et al. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50796-1 · Cited by 45 · see citing works

Studies on the metabolism of radioactive albumin in tumor-bearing rats.

Busch, H., Fujiwara, E., & Firszt, D. C. (1961) · PubMed · Cited by 45 · see citing works

Cancer cachexia

Tisdale, M. J. (1993) · Anti-Cancer Drugs · doi:10.1097/00001813-199304000-00001 · Cited by 45 · see citing works

Mechanism of action of diet as a carcinogen

Weisburger, J. H. (1979) · Cancer · doi:10.1002/1097-0142(197905)43:5+ · Cited by 44 · see citing works

Identification of tissue sites for increased albumin degradation in sarcoma-bearing mice

Andersson, C., Iresjö, B., & Lundholm, K. (1991) · Journal of Surgical Research · doi:10.1016/0022-4804(91)90240-m · Cited by 43 · see citing works

Correlation of Tumor Cytosol Cathepsin D with Differentiation and Invasiveness of Endometrial Adenocarcinoma

Nazeer, T., Malfetano, J. H., ROSANO, T. G., et al. (1992) · American Journal of Clinical Pathology · doi:10.1093/ajcp/97.6.764 · Cited by 43 · see citing works

Cathepsin D assay in ovarian cancer: correlation with pathological features and receptors for oestrogen, progesterone and epidermal growth factor

Scambia, G., Benedetti, P. D., Ferrandina, G., et al. (1991) · British Journal of Cancer · doi:10.1038/bjc.1991.266 · Cited by 41 · see citing works

Cytokines, tryptophan and anorexia in cancer patients before and after surgical tumor ablation.

Cangiano, C., Testa, U., Muscaritoli, M., Mm, M., Mulieri, M., Laviano, A., Cascino, A., Preziosa, I., Conversano, L., & Fanelli, F. R. (1994) · PubMed · Cited by 41 · see citing works

Regulation of ATP-ubiquitin-dependent proteolysis in muscle wasting

Attaix, D., Taillandier, D., Temparis, S., Larbaud, D., AUROUSSEAU, E., Combaret, L., & Voisin, L. (1994) · annales de biologie animale biochimie biophysique · doi:10.1051/rnd:19940605 · Cited by 39 · see citing works

Coated Vesicles from the Protozoan Parasite Trypanosoma brucei: Purification and Characterization

Shapiro, S. Z., & Webster, P. C. (1989) · The Journal of Protozoology · doi:10.1111/j.1550-7408.1989.tb05524.x · Cited by 39 · see citing works

Loci of catabolism of beta-very low density lipoprotein in vivo delineated with a residualizing label, 125I-dilactitol tyramine.

Daugherty, A., Thorpe, S. R., Lange, L. G., Sobel, B. E., & Schonfeld, G. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38605-2 · Cited by 38 · see citing works

THE EFFECT OF STARVATION, INFECTION, AND INJURY ON THE METABOLIC PROCESSES AND BODY COMPOSITION*

Abbott, W. E., & Albertsen, K. (1963) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1963.tb15812.x · Cited by 38 · see citing works

Lipolytic Factors Associated With Murine and Human Cancer cachexia

Beck, S., Mulligan, H. D., & Tisdale, M. J. (1990) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/82.24.1922 · Cited by 37 · see citing works

Hyperammonemia in Multiple Myeloma

Matsuzaki, H., Uchiba, M., Yoshimura, K., Yoshida, M., Akahoshi, Y., Okazaki, K., & Takatsuki, K. (2009) · Acta Haematologica · doi:10.1159/000205049 · Cited by 37 · see citing works

Solute translocation across the mammalian lysosome membrane

Forster, S. H., & Lloyd, J. B. (1988) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(88)90004-4 · Cited by 37 · see citing works

Albumin Metabolism in Neoplastic Diseases

Rossing, N. (1968) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365516809166491 · Cited by 37 · see citing works

In vivo nutrient uptake by head and neck cancers.

Richtsmeier, W. J., Dauchy, R. T., & Sauer, L. A. (1987) · PubMed · Cited by 36 · see citing works

Analbuminemia

Russi, E. W., & Weigand, K. (1983) · Journal of Molecular Medicine · doi:10.1007/bf01486843 · Cited by 36 · see citing works

Lactate-induced inhibition of tumor cell proliferation

Marx, E., Mueller‐Klieser, W., & Vaupel, P. W. (1988) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/0360-3016(88)90017-x · Cited by 34 · see citing works

Extravascular Albumin

Rothschild, M. A., Oratz, M., & Schreiber, S. S. (1979) · New England Journal of Medicine · doi:10.1056/nejm197908303010909 · Cited by 34 · see citing works

Increased plasma free tryptophan levels in human cancer: a tumor related effect?

Cascino, A., Cangiano, C., Ceci, F., Franchi, F., Mineo, T. C., Mulieri, M., Muscaritoli, M., & Fanelli, F. R. (1991) · PubMed · Cited by 33 · see citing works

The Uptake of Proteins by Normal and Tumour Cells In Vitro

Easty, G. C., Yarnell, M. M., & Andrews, R. (1964) · British Journal of Cancer · doi:10.1038/bjc.1964.41 · Cited by 32 · see citing works

Plasma protein metabolism and transfer to the fetus during pregnancy in the rat

Masters, C. L., Bignold, L. P., & Morgan, E. (1969) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1969.216.4.876 · Cited by 32 · see citing works

Study of Albumin Synthesis in Relation to Urea Synthesis

Oratz, M., Schreiber, S. S., & Rothschild, M. A. (1973) · Gastroenterology · doi:10.1016/s0016-5085(19)33047-1 · Cited by 32 · see citing works

Protein turnover in pulmonary macrophages Utilization of amino acids derived from protein degradation

Hammer, J. A., & Rannels, D. E. (1981) · Biochemical Journal · doi:10.1042/bj1980053 · Cited by 32 · see citing works

The GA module, a mobile albumin‐binding bacterial domain, adopts a three‐helix‐bundle structure

Johansson, M. U., de Château, M., Björck, L., et al. (1995) · FEBS Letters · doi:10.1016/0014-5793(95)01121-t · Cited by 31 · see citing works

Regulation of protein degradation rates in eukaryotes

Olson, T. S., & Dice, J. F. (1989) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(89)80071-7 · Cited by 31 · see citing works

Clinical significance of cathepsin D in primary ovarian cancer

Scambia, G., Panici, P. B., Ferrandina, G., et al. (1994) · European Journal of Cancer · doi:10.1016/0959-8049(94)90118-x · Cited by 31 · see citing works

Protein metabolism in human colon carcinomas: in vivo investigations using a modified tracer technique with L-[1-13C]leucine.

Hagmüller, E., Kollmar, H. B., Günther, H.-J., et al. (1995) · PubMed · Cited by 30 · see citing works

Defective internalization of low density lipoprotein in epidermoid cervical cancer cells.

Gal, D., Simpson, E. R., Porter, J. C., et al. (1982) · The Journal of Cell Biology · doi:10.1083/jcb.92.3.597 · Cited by 30 · see citing works

Pinocytosis and intracellular degradation of exogenous protein: modulation by amino acids.

Besterman, J. M., Airhart, J., Low, R. B., et al. (1983) · The Journal of Cell Biology · doi:10.1083/jcb.96.6.1586 · Cited by 30 · see citing works

Lipid metabolism in cancer cachexia

Mulligan, H., Beck, S., & Tisdale, M. (1992) · British Journal of Cancer · doi:10.1038/bjc.1992.216 · Cited by 30 · see citing works

Nitrogen metabolism in cancer patients.

Brennan, M. F., & Burt, M. E. (1981) · PubMed · Cited by 30 · see citing works

On the mechanisms of maternofetal transfer of human albumin and γG globulin in the mouse

Gitlin, D., & Koch, C. (1968) · Journal of Clinical Investigation · doi:10.1172/jci105809 · Cited by 29 · see citing works

Giardia duodenalis: a freeze-fracture, fracture-flip and cytochemistry study

Kattenbach, W. M., Pimenta, P. F. P., de Souza, W., & da Silva, P. P. (1991) · Parasitology Research · doi:10.1007/bf00928678 · Cited by 28 · see citing works

Immunohistochemical study of the uptake of serum proteins by neoplastic liver cells.

Cohen, S., Beiser, S. M., & Hsu, K. C. (1961) · PubMed · Cited by 28 · see citing works

Cathepsin D in primary squamous laryngeal tumors: correlation with clinico-pathological parameters and receptor status

Ferrandina, G., Scambia, G., Panici, P. B., et al. (1992) · Cancer Letters · doi:10.1016/0304-3835(92)90136-j · Cited by 27 · see citing works

Binding of fibronectin and albumin to Enterococcus (Streptococcus) faecalis

Shorrock, P. J., & Lambert, P. A. (1989) · Microbial Pathogenesis · doi:10.1016/0882-4010(89)90008-9 · Cited by 27 · see citing works

Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles

Kratz, F. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.05.010 · Cited by 2,151 · see citing works

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

Commisso, C., Davidson, S. M., Soydaner-Azeloglu, R. G., Parker, S. J., Kamphorst, J. J., Hackett, S., Grabocka, E., Nofal, M., Drebin, J. A., Thompson, C. B., et al. (2013) · Nature · doi:10.1038/nature12138 · Cited by 1,683 · see citing works

Hypoalbuminemia: Pathogenesis and Clinical Significance

Soeters, P. B., Wolfe, R. R., & Shenkin, A. (2019) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.1451 · Cited by 1,448 · see citing works

Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein

Kamphorst, J. J., Nofal, M., Commisso, C., Hackett, S. R., Lu, W., Grabocka, E., Vander Heiden, M. G., Miller, G., Drebin, J. A., Bar-Sagi, D., et al. (2015) · Cancer Research · doi:10.1158/0008-5472.can-14-2211 · Cited by 893 · see citing works

Nutrient acquisition strategies of mammalian cells

Palm, W., & Thompson, C. B. (2017) · Nature · doi:10.1038/nature22379 · Cited by 388 · see citing works

A pan-cancer dye for solid-tumour screening, resection and wound monitoring via short-wave and near-infrared fluorescence imaging

Mc Larney, B. E., Sonay, A. Y., Apfelbaum, E., Mostafa, N., Monette, S., Goerzen, D., Aguirre, N., Exner, R. M., Habjan, C., Isaac, E., et al. (2024) · Nature Biomedical Engineering · doi:10.1038/s41551-024-01248-w · Cited by 28 · see citing works

Lithiated tolunitriles: Preparation and reactions

Kaiser, E. M., & Petty, J. D. (1976) · Journal of Organometallic Chemistry · doi:10.1016/s0022-328x(00)91538-9 · Cited by 19 · see citing works

Directed Metalation of 1-Ester-Substituted Indolizines: Base/Electrophile-Controlled Regioselective Functionalization

Amaral, M. F. Z. J., Baumgartner, A. A., Vessecchi, R., et al. (2014) · Organic Letters · doi:10.1021/ol503288e · Cited by 60 · see citing works

Binding of thioridazine and some of its metabolites to human serum protein and human albumin.

Fm, B., Fa, V., & Mg, B. (1975) · PubMed · Cited by 10 · see citing works

Biosensor Analysis of the Interaction between Immobilized Human Serum Albumin and Drug Compounds for Prediction of Human Serum Albumin Binding Levels

Frostell‐Karlsson, Å., Remaeus, A., Roos, H., Andersson, K., Borg, P., Hämäläinen, M., & Karlsson, R. (2000) · Journal of Medicinal Chemistry · doi:10.1021/jm991174y · Cited by 307 · see citing works

Studies on Drug – Human Serum Albumin Binding: The Current State of the Matter

Zhivkova, Z. D. (2015) · Current Pharmaceutical Design · doi:10.2174/1381612821666150302113710 · Cited by 112 · see citing works