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Systemic inflammation in glucocerebrosidase-deficient mice with minimal glucosylceramide storage.

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Systemic inflammation in glucocerebrosidase-deficient mice with minimal glucosylceramide storage

Mizukami, H., Mi, Y., Wada, R., Kono, M., Yamashita, T., Liu, Y., Werth, N., Sandhoff, R., Sandhoff, K., & Proia, R. L. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0214530 · Cited by 125 · see citing works

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Liao, J., Tao, J., Lin, G., & Liu, D. (2005) · Tetrahedron · doi:10.1016/j.tet.2005.02.075 · Cited by 116 · see citing works

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G2A Plays Proinflammatory Roles in Human Keratinocytes under Oxidative Stress as a Receptor for 9-Hydroxyoctadecadienoic Acid

Hattori, T., Obinata, H., Ogawa, A., Kishi, M., Tatei, K., Ishikawa, O., & Izumi, T. (2007) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5701172 · Cited by 114 · see citing works

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Frasch, S. C., Berry, K. A. Z., Fernandez-Boyanapalli, R. F., Jin, H.-S., Leslie, C. C., Henson, P. M., Murphy, R. C., & Bratton, D. L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m807047200 · Cited by 113 · see citing works

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Silliman, C. C., Elzi, D. J., Ambruso, D. R., Musters, R. J. P., Hamiel, C. R., Harbeck, R. J., Paterson, A. J., Bjornsen, A. J., Wyman, T. H., Kelher, M. R., et al. (2003) · Journal of Leukocyte Biology · doi:10.1189/jlb.0402179 · Cited by 110 · see citing works

Abnormalities in Osteoclastogenesis and Decreased Tumorigenesis in Mice Deficient for Ovarian Cancer G Protein-Coupled Receptor 1

Li, H., Wang, D., Singh, L. S., Berk, M. P., Tan, H., Zhao, Z., Steinmetz, R. W., Kirmani, K., Wei, G., & Xu, Y. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005705 · Cited by 108 · see citing works

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Prostaglandin I2 Production and cAMP Accumulation in Response to Acidic Extracellular pH through OGR1 in Human Aortic Smooth Muscle Cells

Tomura, H., Wang, J.-Q., Komachi, M., Damirin, A., Mogi, C., Tobo, M., Kon, J., Misawa, N., Sato, K., & Okajima, F. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m505287200 · Cited by 103 · see citing works

Signaling via Macrophage G2A Enhances Efferocytosis of Dying Neutrophils by Augmentation of Rac Activity

Frasch, S. C., Fernandez-Boyanapalli, R. F., Berry, K. A. Z., Leslie, C. C., Bonventre, J. V., Murphy, R. C., Henson, P. M., & Bratton, D. L. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.181800 · Cited by 102 · see citing works

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Peng, Y., Kowalewski, R., Kim, S., & Elkon, K. B. (2005) · Molecular Immunology · doi:10.1016/j.molimm.2004.07.045 · Cited by 100 · see citing works

Lysophospholipids of Different Classes Mobilize Neutrophil Secretory Vesicles and Induce Redundant Signaling through G2A

Frasch, S. C., Berry, K. A. Z., Murphy, R. C., Borregaard, N., Henson, P. M., & Bratton, D. L. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.10.6540 · Cited by 94 · see citing works

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Kono, D. H., & Theofilopoulos, A. N. (2006) · Springer Seminars in Immunopathology · doi:10.1007/s00281-006-0030-7 · Cited by 88 · see citing works

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Wang, L., Radu, C. G., Yang, L. V., Bentolila, L. A., Riedinger, M., & Witte, O. N. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-12-1044 · Cited by 88 · see citing works

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Visciano, M. L., Tagliamonte, M., Tornesello, M. L., Buonaguro, L., & Buonaguro, L. (2012) · Journal of Translational Medicine · doi:10.1186/1479-5876-10-4 · Cited by 82 · see citing works

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Bolick, D. T., Skaflen, M. D., Johnson, L. E., Kwon, S., Howatt, D. A., Daugherty, A., Ravichandran, K. S., & Hedrick, C. C. (2008) · Circulation Research · doi:10.1161/circresaha.108.181131 · Cited by 78 · see citing works

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Girkontaitė, I., Sakk, V., Wagner, M., Borggrefe, T., Tedford, K., Chun, J. J. M., & Fischer, K. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20041483 · Cited by 78 · see citing works

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Park, D. W., Kwak, D. S., Park, Y. Y., Chang, Y., Huh, J. W., Lim, C., Koh, Y., Song, D., & Hong, S. (2014) · Journal of Critical Care · doi:10.1016/j.jcrc.2014.05.003 · Cited by 75 · see citing works

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Radu, C. G., Cheng, D., Nijagal, A., Riedinger, M., McLaughlin, J., Yang, L. V., Johnson, J., & Witte, O. N. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.26.2.668-677.2006 · Cited by 74 · see citing works

Responses to Toll‐Like Receptor Ligands in Children Living in Areas Where Schistosome Infections Are Endemic

van der Kleij, D., van den Biggelaar, A. H. J., Kruize, Y. C. M., Retra, K., Fillié, Y. E., Schmitz, M. G. J., Kremsner, P. G., Tielens, A. G. M., & Yazdanbakhsh, M. (2004) · The Journal of Infectious Diseases · doi:10.1086/382089 · Cited by 73 · see citing works

Expression of G2A, a Receptor for Lysophosphatidylcholine, by Macrophages in Murine, Rabbit, and Human Atherosclerotic Plaques

Rikitake, Y., Hirata, K., Yamashita, T., Iwai, K., Kobayashi, S., Itoh, H., Ozaki, M., Ejiri, J., Shiomi, M., Inoue, N., et al. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000040598.18570.54 · Cited by 73 · see citing works

Dysregulation of Signaling Pathways Due to Differentially Expressed Genes From the B-Cell Transcriptomes of Systemic Lupus Erythematosus Patients – A Bioinformatics Approach

Kumar, S. U., Kumar, D. T., Ramamoorthy, S., Doss, C. G. P., Younes, S. N., Younes, N., Sidenna, M., & Zayed, H. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00276 · Cited by 71 · see citing works

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Apoptotic Cells at the Crossroads of Tolerance and Immunity

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Lysophosphatidylcholine induces glial cell activation: Role of rho kinase

Sheikh, A. M., Nagai, A., Ryu, J. K., McLarnon, J. G., Kim, S. U., & Masuda, J. (2008) · Glia · doi:10.1002/glia.20815 · Cited by 66 · see citing works

Deficiency of the Cyclin Kinase Inhibitor p21(WAF-1/CIP-1) Promotes Apoptosis of Activated/Memory T Cells and Inhibits Spontaneous Systemic Autoimmunity

Lawson, B. R., Baccalà, R., Song, J. J., Croft, M., Kono, D. H., & Theofilopoulos, A. N. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20031685 · Cited by 65 · see citing works

The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity

Hohmann, S. W., Angioni, C., Tunaru, S., Lee, S., Woolf, C. J., Offermanns, S., Geißlinger, G., Scholich, K., & Sisignano, M. (2017) · Scientific Reports · doi:10.1038/s41598-017-00591-0 · Cited by 64 · see citing works

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Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132

Lahvic, J. L., Ammerman, M., Li, P., Blair, M. C., Stillman, E., Fast, E. M., Robertson, A. L., Christodoulou, C., Perlin, J. R., Yang, S. P., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1806077115 · Cited by 62 · see citing works

A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands

Kostenis, E. (2004) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2004.04.005 · Cited by 61 · see citing works

Macrophage PPARγ inhibits Gpr132 to mediate the anti-tumor effects of rosiglitazone

Cheng, W. Y., Huynh, H., Chen, P., Peña‐Llopis, S., & Wan, Y. (2016) · eLife · doi:10.7554/elife.18501 · Cited by 60 · see citing works

Efferocytosis in the Central Nervous System

Zhao, J., Zhang, W., Wu, T., Wang, H., Mao, J., Liu, J., Zhou, Z., Lin, X., Yan, H., & Wang, Q. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.773344 · Cited by 56 · see citing works

Clinical significance of enzymatic lysophosphatidylcholine (LPC) assay data in patients with sepsis

Cho, W. H., Park, T., Park, Y.-Y., Huh, J. W., Lim, C., Koh, Y., Song, D., & Hong, S.-B. (2011) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-011-1505-6 · Cited by 57 · see citing works

The essential role of G protein-coupled receptor (GPCR) signaling in regulating T cell immunity

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Sphingosine 1-phosphate pathway therapeutics: a lipid ligand–receptor paradigm

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NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation

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Positron emission tomography imaging analysis of G2A as a negative modifier of lymphoid leukemogenesis initiated by the BCR-ABL oncogene

Le, L. Q., Kabarowski, J. H. S., Wong, S., Nguyen, K., Gambhir, S. S., & Witte, O. N. (2002) · Cancer Cell · doi:10.1016/s1535-6108(02)00058-2 · Cited by 56 · see citing works

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Im, D. (2004) · Journal of Lipid Research · doi:10.1194/jlr.r300006-jlr200 · Cited by 57 · see citing works

Lpa2 Is a Negative Regulator of Both Dendritic Cell Activation and Murine Models of Allergic Lung Inflammation

Emo, J. A., Meednu, N., Chapman, T. J., Rezaee, F., Balys, M. M., Randall, T. D., Rangasamy, T., & Georas, S. N. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1102956 · Cited by 56 · see citing works

Redirection of B cell responsiveness by transforming growth factor β receptor

Roes, J., Choi, B. K., & Cazac, B. B. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0731875100 · Cited by 53 · see citing works

Lysophosphatidic acid enhances interleukin-13 gene expression and promoter activity in T cells

Rubenfeld, J., Guo, J., Sookrung, N., Chen, R., Chaicumpa, W., Casolaro, V., Zhao, Y., Natarajan, V., & Georas, S. N. (2005) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00473.2004 · Cited by 53 · see citing works

The Push-Me Pull-You of T Cell Activation

Carson, M. J., & Lo, D. D. (2001) · Science · doi:10.1126/science.1063516 · Cited by 53 · see citing works

The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed Tissue

Kern, K., Schäfer, S. M. G., Cohnen, J., Pierre, S. C., Osthues, T., Tarighi, N., Hohmann, S., Ferreirós, N., Brüne, B., Weigert, A., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02261 · Cited by 52 · see citing works

Lysophosphatidylcholine potentiates Ca2+ influx, pore formation and p44/42 MAP kinase phosphorylation mediated by P2X7 receptor activation in mouse microglial cells

Takenouchi, T., Sato, M., & Kitani, H. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04570.x · Cited by 51 · see citing works

Scent of dying cells: The role of attraction signals in the clearance of apoptotic cells and its immunological consequences

Munoz, L. E., Peter, C., i, M. H., Wesselborg, S., & Lauber, K. (2009) · Autoimmunity Reviews · doi:10.1016/j.autrev.2009.11.016 · Cited by 49 · see citing works

Receptor Linked to an Autoimmune Disease

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Deletion of the G2A receptor fails to attenuate experimental autoimmune encephalomyelitis

Osmers, I., Smith, S. S., Parks, B. W., Yu, S., Srivastava, R., Wohler, J. E., Barnum, S. R., & Kabarowski, J. H. S. (2009) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2008.11.008 · Cited by 18 · see citing works

Mice Lacking the p53-Effector Gene Gadd45a Develop a Lupus-Like Syndrome

Salvador, J. M., Hollander, M. C., Nguyen, A. T., Kopp, J. B., Barisoni, L. M. C., Moore, J. K., Ashwell, J. D., & Fornace, A. J. (2002) · Immunity · doi:10.1016/s1074-7613(02)00302-3 · Cited by 188 · see citing works

#91 Immune and autoimmune effects of the environmental antiandrogen, DDE

Lubinski, A. L., Kluka, E., Webb, A., & Viselli, S. M. (2005) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2005.10.098

Inhibition of abnormal T cell development and autoimmunity in gld mice by transgenic T cell receptor β chain

Yui, K., Bhandoola, A., Komori, S., Katsumata, M., Greene, M. I., & Radic, M. Z. (1992) · European Journal of Immunology · doi:10.1002/eji.1830220705 · Cited by 11 · see citing works