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Magnetite nanoparticles for medical MR imaging
Open accessAbstract
Nanotechnology has given scientists new tools for the development of advanced materials for the detection and diagnosis of disease. Iron oxide nanoparticles (SPIONs) in particular have been extensively investigated as novel magnetic resonance imaging (MRI) contrast agents due to a combination of favorable superparamagnetic properties, biodegradability, and surface properties of easy modification for improved in vivo kinetics and multifunctionality. This review discusses the basics of MR imaging, the origin of SPION's unique magnetic properties, recent developments in MRI acquisition methods for detection of SPIONs, synthesis and post-synthesis processes that improve SPION's imaging characteristics, and an outlook on the translational potential of SPIONs.
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Cites
Cancer nanotechnology: opportunities and challenges
Ferrari, M. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1566 · Cited by 4,558
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Noninvasive detection of clinically occult lymph-node metastases in prostate cancer
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Cited by
Superparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriers
Wahajuddin, & Arora (2012) · International Journal of Nanomedicine · doi:10.2147/ijn.s30320 · Cited by 1,117
Nanoparticles in magnetic resonance imaging: from simple to dual contrast agents
Busquets, M. A., Estelrich, J., & Sánchez-Martín, M. J. (2015) · International Journal of Nanomedicine · doi:10.2147/ijn.s76501 · Cited by 622
Li, S., Chen, H., Liu, H., Liu, L., Yuan, Y., Mao, C., Zhang, W., Zhang, X., Guo, W., Lee, C.-S., et al. (2020) · ACS Nano · doi:10.1021/acsnano.0c05885 · Cited by 60
Tapeinos, C., Tomatis, F., Battaglini, M., Larrañaga, A., Marino, A., Telleria, I. A., Angelakeris, M., Debellis, D., Drago, F., Brero, F., et al. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201900612 · Cited by 54
Yue, N.-N., Xu, H.-M., Xu, J., Zhu, M.-Z., Zhang, Y., Tian, C.-M., Nie, Y.-Q., Yao, J., Liang, Y.-J., Li, D.-F., et al. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s413141 · Cited by 46
Metadata
- Authors
- Stephen, Z. R., Kievit, F. M., & Zhang, M.
- Venue
- Materials Today
- Publisher
- Elsevier BV
- Published
- 2011-07
- Volume
- 14
- Issue
- 7-8
- Pages
- 330-338
- ISSN
- 1369-7021 (ISSN-L)
- OpenAlex
- W2073608260
- Cited by
- 432
- References
- 6
- FWCI
- 8.93
- Type
- journal article
- Language
- en
- Open access
- hybrid
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