Cited by 182Bone Tissue Engineering MaterialsTissue Engineering and Regenerative MedicineBone health and osteoporosis research

Bone tissue engineering: from bench to bedside

Open access
Woodruff, Maria A., Lange, Claudia, Reichert, Johannes, Berner, Arne, Chen, Fulen, Fratzl, Peter, Schantz, Jan-Thorsten, Hutmacher, Dietmar W.·2012·Materials Today

Abstract

The drive to develop bone grafts for the filling of major gaps in the skeletal structure has led to a major research thrust towards developing biomaterials for bone engineering. Unfortunately, from a clinical perspective, the promise of bone tissue engineering which was so vibrant a decade ago has so far failed to deliver the anticipated results of becoming a routine therapeutic application in reconstructive surgery. Here we describe our bench to bedside concept, the first clinical results and a detailed analysis of long-term bone regeneration studies in preclinical animal models, exploiting methods of micro- and nano analysis of biodegradable composite scaffolds.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/s1369-7021(12)70194-3

Cites

41 of 41 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

1 of the 42 references couldn’t be matched to a known paper.

Research works printed but not linked: 1

  1. Reichert, J. C., et al. Sci Transl Med (2012) 4(141), 141.

Cited by

Sorted by citations

Authors
Woodruff, M. A., Lange, C., Reichert, J., Berner, A., Chen, F., Fratzl, P., Schantz, J.-T., & Hutmacher, D. W.
Affiliations
  • Queensland University of Technology (AU)
  • Max Planck Society (DE)
  • University of Würzburg (DE)
  • University of Regensburg (DE)
  • Air Force Medical University (CN)
  • TUM Klinikum (DE)
  • Georgia Institute of Technology (US)
Corresponding author
Hutmacher, Dietmar W.
Venue
Materials Today
Publisher
Elsevier BV
Published
2012-10
Volume
15
Issue
10
Pages
430-435
ISSN
1369-7021 (ISSN-L)
OpenAlex
W2089789987
Cited by
182
References
42
Citations by year
2026: 5 · 2025: 11 · 2024: 11 · 2023: 12 · 2022: 14 · 2021: 17 · 2020: 20 · 2019: 12 · 2018: 11 · 2017: 23 · 2016: 15 · 2015: 9 · 2014: 12 · 2013: 10
FWCI
5.65
Type
journal article
Language
en
Open access
Locations
  • Materials Today (publishedVersion, cc-by-nc-nd)
  • Max Planck Institute for Plasma Physics (submittedVersion)
  • Max Planck Digital Library (submittedVersion)
  • MPG.PuRe (Max Planck Society) (submittedVersion, other-oa)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
  • Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
Keywords
bone tissue engineering, bone grafting, biomaterials, bone regeneration, preclinical animal models, clinical translation, reconstructive surgery

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review