The role of oxytocin in parturition

BLANKS, A

doi:10.1016/s1470-0328(03)00024-7

Cited by 296Maternal and Perinatal Health InterventionsNeuroendocrine regulation and behaviorPreterm Birth and Chorioamnionitis

The role of oxytocin in parturition

BLANKS, A·2003·BJOG: An International Journal of Obstetrics and Gynaecology

DOI 10.1016/s1470-0328(03)00024-7

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Abstract

Oxytocin and the oxytocin receptor have two important roles in labour. Evidence in all mammalian species suggests that neurohypophysical oxytocin plays a role in the expulsive phase and, although there are less supporting data, a role for oxytocin in the initiation of labour is likely. The initiation of labour may be mediated in women and rhesus monkeys by paracrine rather than endocrine mechanisms. Although initial characterisation of the oxytocin knockout mouse suggested that oxytocin is not important in this species, subsequent investigations have demonstrated that oxytocin is important for the precise timing of the onset of labour. Studies in knockout mice also confirm important interrelationships between oxytocin and prostaglandins. Oxytocin stimulates prostaglandin release in many species, mainly in the decidua/uterine epithelium. The effects of oxytocin are mediated by tissue-specific oxytocin receptor expression, which leads directly to contraction in the myometrium and prostaglandin formation in the decidua. There is a dramatic increase in oxytocin receptor expression in these tissues in late pregnancy and pharmacological inhibition delays delivery, which suggests that, in contrast to oxytocin, the oxytocin receptor is essential for normal labour.

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Oxytocin has peripheral effects on parturition and lactation.
“Oxytocin is a mammalian neurohormone composed of nine amino acids, known for its peripheral effects on parturition and lactation (5–7), as well as its central neuromodulatory effects on social behaviors such as affiliative, aggressive, and parental behaviors (8, 9).”
From Oxytocin during Development: Possible Organizational Effects on Behavior (2015) · cites this paper as [5]

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Patano, N., Marinaccio, M., Vimercati, A., Camerino, C., Mancini, L., Selvaggi, L. E., & Zallone, A. Z. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.06.126 · Cited by 1 · see citing works
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Paúl, J. (2017) · Human Endocrinology · doi:10.24966/he-9640/100008 · Cited by 1 · see citing works
Relação entre os padrões de secreção central e periférica de ocitocina: implicações sobre produção de leite em ovelhas
Bochini, J. C. (2008) · doi:10.11606/d.10.2008.tde-18112008-153251
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You, S. (2016) · doi:10.23860/thesis-you-sangmin-2016
Uterine contractile activity and fetal outcome in rats treated with vitamin C during late gestational variable stress exposure
Salami, S. A., Salahdeen, H. M., Obafemi, A. E., & Murtala, B. A. (2021) · Journal of Complementary and Integrative Medicine · doi:10.1515/jcim-2020-0276
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Díaz, C. G. (2021) · doi:10.6035/14112.2021.403202
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Pires, J. H. D. S. D. (2022) · doi:10.5463/thesis.35
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Dias, J. H. (2022) · doi:10.47328/ufvbbt.2022.404
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Johnson, J. L., Johnson, M., & Buisman‐Pijlman, F. T. A. (2017) · Royal Society of Chemistry eBooks · doi:10.1039/9781782621577-00346
The ontogeny of kisspeptin, leptin and adiponectin
Schaffer, A. (2023) · doi:10.14232/phd.11414
Uterine fibroids
Don, E. E. (2023) · doi:10.5463/thesis.409
Role Of Bilateral Uterine Artery Ligation In Reducing Incidence Of Postpartum Hemorrhage In Cesarean Section In Patients At Risk Of Uterine Atony A Randomized Controlled Trial
Mostafa, W. A. E.-A. M., El-Omda, F. A. A., & El-Fattah, A. T. A. (2023) · Al-Azhar International Medical Journal /Al-Azhar International Medical Journal · doi:10.58675/2682-339x.1994
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Berkhout, J. B., Trender, S., Krabichler, Q., Podpecan, Y., Franke, F., Schubert, T., Burbach, J. P. H., Grinevich, V., Adan, R. A. H., Fröhlich, H., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.10.658830
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Buslowicz, J. T., Brüggmann, D., Naimi, A. A., et al. (2026) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-026-08391-6
Restauration de l’agrosystème de la plaine alsacienne à travers la protection d’une espèce emblématique ; le hamster commun
Gérard, T. (2024) · doi:10.70675/cc3b068ez5bdcz4948z8552z09a64e0863d6

Authors: BLANKS, A.
ORCID: BLANKS, A
Venue: BJOG: An International Journal of Obstetrics and Gynaecology
Publisher: Wiley
Published: 2003-04
Volume: 110
Issue: s20
Pages: 46-51
ISSN: 0306-5456 (ISSN-L)
1470-0328
DOI: 10.1016/s1470-0328(03)00024-7
OpenAlex: W2027958963
Cited by: 296
References: 0
Citations by year: 2026: 3 · 2025: 3 · 2024: 13 · 2023: 14 · 2022: 13 · 2021: 16 · 2020: 12 · 2019: 11 · 2018: 6 · 2017: 72 · 2016: 12 · 2015: 10 · 2014: 11 · 2013: 6 · 2012: 10
FWCI: 10.89
Type: journal article
Language: en
Open access: closed
Licence: doi.wiley.com/10.1002/tdm_license_1 (tdm, 4536 d)
Locations: BJOG An International Journal of Obstetrics & Gynaecology (publishedVersion)
PubMed (publishedVersion)
Funders: University Hospitals Coventry and Warwickshire NHS Trust
Topics: Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
Health Sciences › Medicine › Epidemiology › Preterm Birth and Chorioamnionitis
Keywords: oxytocin, oxytocin receptor, childbirth, labor onset, expulsive phase, myometrial contraction, prostaglandins, decidua, paracrine mechanisms, rhesus monkeys, neurohypophysis, late pregnancy
MeSH terms: Animals, Female, Humans, Labor, Obstetric, Lactation, Oxytocin, Pregnancy, Swine, Receptors, Oxytocin, Parturition, Mice

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The role of oxytocin in parturition

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