The DOI matches its Crossref record; 137 of the 137 references it cites were found in a registry or an index.
Gluten sensitivity: from gut to brain
Abstract
Gluten sensitivity is a systemic autoimmune disease with diverse manifestations. This disorder is characterised by abnormal immunological responsiveness to ingested gluten in genetically susceptible individuals. Coeliac disease, or gluten-sensitive enteropathy, is only one aspect of a range of possible manifestations of gluten sensitivity. Although neurological manifestations in patients with established coeliac disease have been reported since 1966, it was not until 30 years later that, in some individuals, gluten sensitivity was shown to manifest solely with neurological dysfunction. Furthermore, the concept of extraintestinal presentations without enteropathy has only recently become accepted. In this Personal View, we review the range of neurological manifestations of gluten sensitivity and discuss recent advances in the diagnosis and understanding of the pathophysiological mechanisms underlying neurological dysfunction related to gluten sensitivity.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The autoimmune target in neurologic gluten sensitivity is TG6 rather than TG2, which is the target for autoantibodies measured in commercial tests.47”
From The Gut Microbiome and the Brain (2014) · cites this paper as [47]
Citations
Cites
Identification of tissue transglutaminase as the autoantigen of celiac disease
Dieterich, W., Ehnis, T., Bauer, M., Donner, P., Volta, U., Riecken, E. O., & Schuppan, D. (1997) · Nature Medicine · doi:10.1038/nm0797-797 · Cited by 2,021
Marsh, M. N. (1992) · PubMed · Cited by 1,985
Gluten, major histocompatibility complex, and the small intestine
Marsh, M. N. (1992) · Gastroenterology · doi:10.1016/0016-5085(92)91819-p · Cited by 1,692
Molberg, Ø., McAdam, S. N., Körner, R., Quarsten, H., Kristiansen, C., Madsen, L. S., Fugger, L. H., Scott, H., Norén, O., Roepstorff, P., et al. (1998) · Nature Medicine · doi:10.1038/nm0698-713 · Cited by 1,166
Autoimmune T cell responses in the central nervous system
Goverman, J. M. (2009) · Nature reviews. Immunology · doi:10.1038/nri2550 · Cited by 1,057
Newly identified genetic risk variants for celiac disease related to the immune response
Hunt, K. A., Zhernakova, A., Turner, G., Heap, G., Franke, L., Bruinenberg, M., Romanos, J., Dinesen, L. C., Ryan, A. W., Panesar, D., et al. (2008) · Nature Genetics · doi:10.1038/ng.102 · Cited by 685
Self-citationvan Heel, D. A., Franke, L., Hunt, K. A., Gwilliam, R., Zhernakova, A., Inouye, M., Wapenaar, M. C., Barnardo, M., Bethel, G., Holmes, G. K. T., et al. (2007) · Nature Genetics · doi:10.1038/ng2058 · Cited by 662
Self-citationFollicular B helper T cells in antibody responses and autoimmunity
Vinuesa, C. G., Tangye, S. G., Moser, B., & Mackay, C. R. (2005) · Nature reviews. Immunology · doi:10.1038/nri1714 · Cited by 646
Karell, K., Louka, A. S., Moodie, S. J., Ascher, H., Clot, F., Greco, L., Ciclitira, P. J., Sollid, L. M., & Partanen, J. (2003) · Human Immunology · doi:10.1016/s0198-8859(03)00027-2 · Cited by 612
Epidermal Transglutaminase (TGase 3) Is the Autoantigen of Dermatitis Herpetiformis
Sárdy, M., Kárpáti, S., Merkl, B., Paulsson, M., & Smyth, N. R. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20011299 · Cited by 515
Research works printed but not linked: 4
- Gee, 1888, On the coeliac affection, St Bartholomews Hosp Rep, 24, 17
- Hadjivassiliou M, Aeschlimann P, Sanders DS, et al. Antibodies against TG6 as the only serological marker of gluten ataxia. Proceedings of the 13th International Coeliac Disease Symposium. Amsterdam; April 6–8, 2009. 09.1.
- Rao, 2007, Sensory neuronopathy due to gluten sensitivity, Ann Indian Acad Neurol, 10, 16
- Hadjivassiliou, 2005, Glutamic acid decarboxylase as a target antigen in gluten sensitivity: the link to neurological manifestations?, J Neurol Neurosurg Psychiatry Proceedings of the Association of British Neurologists Meeting, 76, 150
Cited by
Sorted by citations
The Oslo definitions for coeliac disease and related terms
Ludvigsson, J. F., Leffler, D. A., Bai, J. C., Biagi, F., Fasano, A., Green, P. H. R., Hadjivassiliou, M., Kaukinen, K., Kelly, C. P., Leonard, J. N., et al. (2013) · Gut · doi:10.1136/gutjnl-2011-301346 · Cited by 1,721
Self-citationMedicine & science in sports & exercise
Walle, J. M. L., Solá, I. B., Castillo, I., & Rodríguez, J. L. T. (1994) · Journal of the American Dietetic Association · doi:10.1016/0002-8223(94)92575-5 · Cited by 1,309
The Gut Microbiome and the Brain
Galland, L. (2014) · Journal of Medicinal Food · doi:10.1089/jmf.2014.7000 · Cited by 648
Sapone, A., Lammers, K. M., Casolaro, V., Cammarota, M., Giuliano, M. T., De Rosa, M., Stefanile, R., Mazzarella, G., Tolone, C., Russo, M. I., et al. (2011) · BMC Medicine · doi:10.1186/1741-7015-9-23 · Cited by 452
Fasano, A., Sapone, A., Zevallos, V. F., & Schuppan, D. (2015) · Gastroenterology · doi:10.1053/j.gastro.2014.12.049 · Cited by 331
Advances in Diagnosis and Management of Celiac Disease
Kelly, C. P., Bai, J. C., Liu, E., & Leffler, D. A. (2015) · Gastroenterology · doi:10.1053/j.gastro.2015.01.044 · Cited by 322
Hollon, J. R., Puppa, E. L., Greenwald, B. D., Goldberg, E., Guerrerio, A. L., & Fasano, A. (2015) · Nutrients · doi:10.3390/nu7031565 · Cited by 221
The Epidemiologic Evidence Linking Autoimmune Diseases and Psychosis
Benros, M. E., Eaton, W. W., & Mortensen, P. B. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.09.023 · Cited by 196
Autoimmune diseases and infections as risk factors for schizophrenia
Benros, M. E., Mortensen, P. B., & Eaton, W. W. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2012.06638.x · Cited by 199
Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias
Mitoma, H., Adhikari, K., Aeschlimann, D. P., Chattopadhyay, P. P., Hadjivassiliou, M., Hampe, C. S., Honnorat, J., Joubert, B., Kakei, S., Lee, J., et al. (2015) · The Cerebellum · doi:10.1007/s12311-015-0664-x · Cited by 185
Self-citationAutoimmune diseases associated with Neuromyelitis Optica Spectrum Disorders: A literature review
Shahmohammadi, S., Doosti, R., Shahmohammadi, A., Mohammadianinejad, S. E., Sahraian, M. A., Azimi, A. R., Harirchian, M. H., Asgari, N., & Moghadasi, A. N. (2018) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2018.11.008 · Cited by 185
Coeliac disease and gluten sensitivity
Troncone, R., & Jabrì, B. (2011) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2011.02385.x · Cited by 174
Transglutaminase 6 antibodies in the diagnosis of gluten ataxia
Hadjivassiliou, M., Aeschlimann, P. C., Sanders, D. S., Mäki, M., Kaukinen, K., Grünewald, R. A., Bandmann, O., Woodroofe, M. N., Haddock, G., & Aeschlimann, D. P. (2013) · Neurology · doi:10.1212/wnl.0b013e3182919070 · Cited by 159
Self-citationIyer, A., Elsone, L., Appleton, R. E., & Jacob, A. (2014) · Autoimmunity · doi:10.3109/08916934.2014.883501 · Cited by 145
Brain-Reactive Antibodies and Disease
Diamond, B., Honig, G., Mader, S., Brimberg, L., & Volpe, B. T. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-075041 · Cited by 138
Movement disorders in autoimmune diseases
Baizabal‐Carvallo, J. F., & Jankovic, J. J. (2012) · Movement Disorders · doi:10.1002/mds.25011 · Cited by 125
Lis, D. M., Stellingwerff, T., Shing, C. M., Ahuja, K. D. K., & Fell, J. W. (2015) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2013-0247 · Cited by 121
The gluten‐free diet and its current application in coeliac disease and dermatitis herpetiformis
Ciacci, C., Ciclitira, P. J., Hadjivassiliou, M., Kaukinen, K., Ludvigsson, J. F., McGough, N., Sanders, D. S., Woodward, J. M., Leonard, J. N., & Swift, G. L. (2014) · United European Gastroenterology Journal · doi:10.1177/2050640614559263 · Cited by 115
Self-citationAdverse Reactions to Wheat or Wheat Components
Brouns, F. J. P. H., van Rooy, G., Shewry, P. R., Rustgi, S., & Jonkers, D. M. A. E. (2019) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12475 · Cited by 113
Martin, V. T., & Vij, B. (2016) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12953 · Cited by 113
Transglutaminase 6: a protein associated with central nervous system development and motor function
Thomas, H., Beck, K., Adamczyk, M., Aeschlimann, P. C., Langley, M. S., Oita, R. C., Thiebach, L., Hils, M., & Aeschlimann, D. P. (2011) · Amino Acids · doi:10.1007/s00726-011-1091-z · Cited by 104
Self-citationGluten-Related Disorders: Gluten Ataxia
Hadjivassiliou, M., Sanders, D. D., & Aeschlimann, D. P. (2015) · Digestive Diseases · doi:10.1159/000369509 · Cited by 103
Self-citationExtra-intestinal manifestations of non-celiac gluten sensitivity: An expanding paradigm
Losurdo, G., Principi, M., Iannone, A., Amoruso, A., Ierardi, E., Leo, A. D., & Barone, M. (2018) · World Journal of Gastroenterology · doi:10.3748/wjg.v24.i14.1521 · Cited by 102
Neurological Manifestations of Neuropathy and Ataxia in Celiac Disease: A Systematic Review
Mearns, E. S., Taylor, A., Craig, K. J. T., Puglielli, S. M., Cichewicz, A. B., Leffler, D. A., Sanders, D. S., Lebwohl, B., & Hadjivassiliou, M. (2019) · Nutrients · doi:10.3390/nu11020380 · Cited by 98
Self-citationGwathmey, K. G. (2015) · Muscle & Nerve · doi:10.1002/mus.24943 · Cited by 93
Irish, A. K., Erickson, C., Wahls, T. L., Snetselaar, L. G., & Darling, W. G. (2017) · Degenerative Neurological and Neuromuscular Disease · doi:10.2147/dnnd.s116949 · Cited by 90
Stamnæs, J., Dørum, S., Fleckenstein, B. T., Aeschlimann, D. P., & Sollid, L. M. (2010) · Amino Acids · doi:10.1007/s00726-010-0554-y · Cited by 88
Self-citationSystemic and neurologic autoimmune disorders associated with seizures or epilepsy
Vincent, A. C., & Crino, P. B. (2011) · Epilepsia · doi:10.1111/j.1528-1167.2011.03030.x · Cited by 87
Antibodies in celiac disease: implications beyond diagnostics
Caja, S., Mäki, M., Kaukinen, K., & Lindfors, K. (2011) · Cellular and Molecular Immunology · doi:10.1038/cmi.2010.65 · Cited by 86
Julio-Pieper, M., Bravo, J. A., Aliaga, E., & Gotteland, M. (2014) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12950 · Cited by 84
Al-Toma, A. A., Zingone, F., Branchi, F., Schiepatti, A., Malamut, G., Canova, C., Rosato, I., Ocagli, H., Trott, N., Elli, L., et al. (2025) · United European Gastroenterology Journal · doi:10.1002/ueg2.70119 · Cited by 87
Self-citationLaatikainen, R., Koskenpato, J., Hongisto, S.-M., Loponen, J., Poussa, T., Huang, X., Sontag-Strohm, T., Salmenkari, H., & Korpela, R. (2017) · Nutrients · doi:10.3390/nu9111215 · Cited by 82
Immune Development and Intestinal Microbiota in Celiac Disease
Pozo-Rubio, T., Olivares, M., Nova, E., De Palma, G., Mujico, J. R., Ferrer, M. D., Marcos, A., & Sanz, Y. (2012) · Clinical and Developmental Immunology · doi:10.1155/2012/654143 · Cited by 82
The spectrum of noncoeliac gluten sensitivity
Aziz, I., Hadjivassiliou, M., & Sanders, D. S. (2015) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2015.107 · Cited by 82
Self-citationPrevalence of celiac disease in multiple sclerosis
Rodrigo, L., Hernández‐Lahoz, C., Fuentes, D., Alvarez, N., López‐Vázquez, A., & Gonzalez, S. R. (2011) · BMC Neurology · doi:10.1186/1471-2377-11-31 · Cited by 80
Celiac Disease and Neurological Manifestations: From Gluten to Neuroinflammation
Giuffrè, M., Gazzin, S., Zoratti, C., Llido, J. P., Lanza, G., Tiribelli, C., & Moretti, R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232415564 · Cited by 85
Sensory ganglionopathy due to gluten sensitivity
Hadjivassiliou, M., Rao, D. G., Wharton, S. B., Sanders, D. S., Grünewald, R. A., & Davies‐Jones, A. G. B. (2010) · Neurology · doi:10.1212/wnl.0b013e3181f25ee0 · Cited by 78
Self-citationManagement of celiac disease in daily clinical practice
Elli, L., Ferretti, F., Orlando, S., Vecchi, M. L., Monguzzi, E., Roncoroni, L., & Schuppan, D. (2018) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2018.11.012 · Cited by 77
Celiac disease and health-related quality of life
Kurppa, K., Collin, P., Mäki, M., & Kaukinen, K. (2011) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/egh.10.81 · Cited by 76
Sensitization to Gliadin Induces Moderate Enteropathy and Insulitis in Nonobese Diabetic-DQ8 Mice
Galipeau, H. J., Rulli, N. E., Jury, J., Huang, X., Araya, R. E., Murray, J. A., David, C. S., Chirdo, F. G., McCoy, K. D., & Verdu, E. F. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1100854 · Cited by 76
Gluten‐induced cognitive impairment (“brain fog”) in coeliac disease
Yelland, G. W. (2017) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.13706 · Cited by 75
No Effects of a Short-Term Gluten-free Diet on Performance in Nonceliac Athletes
Lis, D. M., Stellingwerff, T., Kitic, C. M., Ahuja, K., & Fell, J. W. (2015) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000699 · Cited by 72
Neurophysiology of the “Celiac Brain”: Disentangling Gut-Brain Connections
Pennisi, M., Bramanti, A., Cantone, M., Pennisi, G., Bella, R., & Lanza, G. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00498 · Cited by 71
Gluten Psychosis: Confirmation of a New Clinical Entity
Lionetti, E., Leonardi, S., Franzonello, C., Mancardi, M. M., Ruggieri, M., & Catassi, C. (2015) · Nutrients · doi:10.3390/nu7075235 · Cited by 70
Effect of gluten-free diet on cerebellar MR spectroscopy in gluten ataxia
Hadjivassiliou, M., Grünewald, R. A., Sanders, D. S., Shanmugarajah, P. D., & Hoggard, N. (2017) · Neurology · doi:10.1212/wnl.0000000000004237 · Cited by 70
Self-citationMitoma, H., Manto, M. U., & Hadjivassiliou, M. (2021) · Journal of Movement Disorders · doi:10.14802/jmd.20040 · Cited by 69
Self-citationAziz, I., Branchi, F., Pearson, K., Priest, J., & Sanders, D. S. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000335 · Cited by 68
Self-citationExtraintestinal Manifestations of Celiac Disease
Pinto-Sánchez, M. I., Berčík, P., Verdu, E. F., & Bai, J. C. (2015) · Digestive Diseases · doi:10.1159/000369541 · Cited by 70
Review article: coeliac disease in later life must not be missed
Collin, P., Vilppula, A., Luostarinen, L., Holmes, G. K. T., & Kaukinen, K. (2018) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.14490 · Cited by 68
Immunological consequences of ischemic stroke
Vogelgesang, A., Becker, K. J., & Dressel, A. (2013) · Acta Neurologica Scandinavica · doi:10.1111/ane.12165 · Cited by 65
The neurologic significance of celiac disease biomarkers
McKeon, A. B., Lennon, V. A., Pittock, S. J., Kryzer, T. J., & Murray, J. A. (2014) · Neurology · doi:10.1212/wnl.0000000000000970 · Cited by 63
Autism spectrum disorder and celiac disease: no evidence for a link
Batista, I. C., Gandolfi, L., Nóbrega, Y. K. D. M., de Almeida, R. C., Almeida, L. M., Campos, D., & Pratesi, R. (2012) · Arquivos de Neuro-Psiquiatria · doi:10.1590/s0004-282x2012000100007 · Cited by 63
Lee, J. E., Bisht, B., Hall, M. J., Rubenstein, L. M., Louison, R. R., Klein, D. T., & Wahls, T. L. (2017) · Journal of the American College of Nutrition · doi:10.1080/07315724.2016.1255160 · Cited by 61
Transglutaminase-2 Interaction with Heparin
Lortat‐Jacob, H., Burhan, I., Scarpellini, A., Thomas, A. M., Imberty, A., Vivès, R. R., Johnson, T. S., Gutiérrez, A., & Verderio, E. A. M. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.337089 · Cited by 62
Makharia, G. K., Mulder, C. J. J., Goh, K., Ahuja, V., Bai, J. C., Catassi, C., Green, P. H. R., Gupta, S. D., Lundin, K. E. A., Ramakrishna, B., et al. (2014) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.12514 · Cited by 58
Non-celiac gluten sensitivity: All wheat attack is not celiac
Igbinedion, S. O., Ansari, J., Vasikaran, A., Gavins, F. N. E., Jordan, P., Boktor, M., & Alexander, J. S. (2017) · World Journal of Gastroenterology · doi:10.3748/wjg.v23.i40.7201 · Cited by 58
Lowrie, M. L., Garden, O. A., Hadjivassiliou, M., Harvey, R. J., Sanders, D. S., Powell, R., & GAROSI, L. S. (2015) · Journal of Veterinary Internal Medicine · doi:10.1111/jvim.13643 · Cited by 57
Self-citationGluten‐Free Diet in Nonceliac Disease
El‐Chammas, K. I., & Danner, E. (2011) · Nutrition in Clinical Practice · doi:10.1177/0884533611405538 · Cited by 57
Cystamine and cysteamine as inhibitors of transglutaminase activity in vivo
Jeitner, T. M., Pinto, J. T., & Cooper, A. J. L. (2018) · Bioscience Reports · doi:10.1042/bsr20180691 · Cited by 57
Currie, S., Hadjivassiliou, M., Clark, M. J. R., Sanders, D. S., Wilkinson, I. D., Griffiths, P. D., & Hoggard, N. (2012) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2012-303281 · Cited by 56
Self-citationNon-celiac gluten sensitivity: A work-in-progress entity in the spectrum of wheat-related disorders
Volta, U., Caio, G., GIORGIO, R. D., Henriksen, C., Skodje, G. I., & Lundin, K. E. A. (2015) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2015.04.006 · Cited by 55
Asrani, P., Ali, A., & Tiwari, K. (2022) · Food Reviews International · doi:10.1080/87559129.2021.2012790 · Cited by 54
Lindfors, K., Mäki, M., & Kaukinen, K. (2010) · Autoimmunity Reviews · doi:10.1016/j.autrev.2010.06.003 · Cited by 53
Gluten sensitivity and epilepsy: a systematic review
Julian, T. H., Hadjivassiliou, M., & Zis, P. (2018) · Journal of Neurology · doi:10.1007/s00415-018-9025-2 · Cited by 53
Self-citationExcitability of the Motor Cortex in De Novo Patients with Celiac Disease
Pennisi, G., Lanza, G., Giuffrida, S., Vinciguerra, L., Puglisi, V., Cantone, M., Pennisi, M., D’Agate, C. C., Naso, P., Aprile, G., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102790 · Cited by 52
Gluten-related neurologic dysfunction
Hadjivassiliou, M., Duker, A. P., & Sanders, D. S. (2013) · Handbook of clinical neurology · doi:10.1016/b978-0-7020-4087-0.00041-3 · Cited by 51
Self-citationWhat the Gut Can Teach Us About Migraine
Hindiyeh, N. A., & Aurora, S. K. (2015) · Current Pain and Headache Reports · doi:10.1007/s11916-015-0501-4 · Cited by 52
Autoimmune Encephalopathy for Psychiatrists: When to Suspect Autoimmunity and What to Do Next
Oldham, C. M. (2017) · Psychosomatics · doi:10.1016/j.psym.2017.02.014 · Cited by 50
Transglutaminase 6 antibodies in gluten neuropathy
Zis, P., Rao, D. G., Sarrigiannis, P. G., Aeschlimann, P. C., Aeschlimann, D. P., Sanders, D. S., Grünewald, R. A., & Hadjivassiliou, M. (2017) · Digestive and Liver Disease · doi:10.1016/j.dld.2017.08.019 · Cited by 50
Self-citationMakhlouf, S., Messelmani, M., Zaouali, J., & Mrissa, R. (2017) · Acta Neurologica Belgica · doi:10.1007/s13760-017-0870-z · Cited by 50
Neuropathic Pain in Neurologic Disorders: A Narrative Review
Mitsikostas, D. D., Μoka, Ε., Orrillo, E., Aurilio, C., Vadalouca, A., Paladini, A., & Varrassi, G. (2022) · Cureus · doi:10.7759/cureus.22419 · Cited by 53
The Bowel and Migraine: Update on Celiac Disease and Irritable Bowel Syndrome
Cady, R. K., Farmer, K. U., Dexter, J., & Hall, J. (2012) · Current Pain and Headache Reports · doi:10.1007/s11916-012-0258-y · Cited by 49
Pennisi, M., Lanza, G., Cantone, M., Ricceri, R., Ferri, R., D’Agate, C. C., Pennisi, G., Lazzaro, V. D., & Bella, R. (2017) · PLoS ONE · doi:10.1371/journal.pone.0177560 · Cited by 49
Redox Mechanisms in Migraine: Novel Therapeutics and Dietary Interventions
Ferroni, P., Barbanti, P., Della‐Morte, D., Palmirotta, R., Jirillo, E., & Guadagni, F. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7260 · Cited by 50
Anti-NMDA-Rezeptor-Enzephalitis
Prüß, H., Dalmau, J. O., Arolt, V., & Wandinger, K.-P. (2010) · Der Nervenarzt · doi:10.1007/s00115-009-2908-9 · Cited by 48
Sensory Neuronopathy and Autoimmune Diseases
Martínez, A., Nunes, M. B., Nucci, A., & França, M. C. (2012) · Autoimmune Diseases · doi:10.1155/2012/873587 · Cited by 48
Do we need to worry about eating wheat?
Shewry, P. R., & Hey, S. J. (2016) · Nutrition Bulletin · doi:10.1111/nbu.12186 · Cited by 48
Magnetic resonance spectroscopy of the brain
Prichard, J. W. (1992) · Clinica Chimica Acta · doi:10.1016/0009-8981(92)90012-f · Cited by 47
Magnetic resonance spectroscopy of the brain
Currie, S., Hadjivassiliou, M., Craven, I., Wilkinson, I. D., Griffiths, P. D., & Hoggard, N. (2012) · Postgraduate Medical Journal · doi:10.1136/postgradmedj-2011-130471 · Cited by 47
Self-citationLanza, G., Bella, R., Cantone, M., Pennisi, G., Ferri, R., & Pennisi, M. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19082243 · Cited by 47
Celiac disease: diagnosis and management.
Pelkowski, T. D., & Viera, A. J. (2014) · PubMed · Cited by 47
An Update on the Diagnostics of Celiac Disease
Lindfors, K., Koskinen, O., & Kaukinen, K. (2011) · International Reviews of Immunology · doi:10.3109/08830185.2011.595854 · Cited by 46
Cossu, G., Carta, M. G., Contu, F., Mela, Q., Demelia, L., Elli, L., & Dell’Osso, B. M. (2017) · International Review of Psychiatry · doi:10.1080/09540261.2017.1314952 · Cited by 46
Effect of a Gluten-Free Diet on Cortical Excitability in Adults with Celiac Disease
Bella, R., Lanza, G., Cantone, M., Giuffrida, S., Puglisi, V., Vinciguerra, L., Pennisi, M., Ricceri, R., D’Agate, C. C., Malaguarnera, G., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0129218 · Cited by 45
Increased Prevalence of Transglutaminase 6 Antibodies in Sera From Schizophrenia Patients
Cascella, N. G., Santora, D., Gregory, P., Kelly, D. L., Fasano, A., & Eaton, W. W. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs064 · Cited by 45
Transglutaminase 2 and Transglutaminase 2 Autoantibodies in Celiac Disease: a Review
Rauhavirta, T., Hietikko, M., Salmi, T. T., & Lindfors, K. (2016) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-016-8557-4 · Cited by 45
Treatable causes of cerebellar ataxia
Ramirez‐Zamora, A., Zeigler, G., Desai, N., & Biller, J. (2015) · Movement Disorders · doi:10.1002/mds.26158 · Cited by 45
Transglutaminase 6 Antibodies in the Serum of Patients With Amyotrophic Lateral Sclerosis
Gadoth, A., Nefussy, B., Bleiberg, M., Klein, T., Artman, I., & Drory, V. E. (2015) · JAMA Neurology · doi:10.1001/jamaneurol.2015.48 · Cited by 44
Risk of Dementia in Patients with Celiac Disease: A Population-Based Cohort Study
Lebwohl, B., Luchsinger, J. A., Freedberg, D. E., Green, P. H. R., & Ludvigsson, J. F. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-150388 · Cited by 42
Gluten Sensitivity Presenting as a Neuropsychiatric Disorder
Genuis, S. J., & Lobo, R. A. (2014) · Gastroenterology Research and Practice · doi:10.1155/2014/293206 · Cited by 42
Real, A., Comino, I., Moreno, M. D. L., López‐Casado, M. Á., Lorite, P., Torres, M. I., Cebolla, Á., & Sousa, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100917 · Cited by 41
Bernardo, D., & Peña, A. S. (2011) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2011.09.016 · Cited by 41
Casella, S., Zanini, B., Lanzarotto, F., Ricci, C., Marengoni, A., Romanelli, G., & Lanzini, A. (2012) · Digestive and Liver Disease · doi:10.1016/j.dld.2012.03.008 · Cited by 40
Haro, C., Villatoro, M., Vaquero, L. M., Pastor, J., Giménez, M. J., Ozuna, C. V., Sánchez‐León, S., García-Molina, M. D., Segura, V., Comino, I., et al. (2018) · Nutrients · doi:10.3390/nu10121964 · Cited by 45
From coeliac disease to noncoeliac gluten sensitivity; should everyone be gluten free?
Aziz, I., Dwivedi, K., & Sanders, D. S. (2016) · Current Opinion in Gastroenterology · doi:10.1097/mog.0000000000000248 · Cited by 40
Self-citationRozenberg, O., Lerner, A., Pacht, A., Grinberg, M., Reginashvili, D., Henig, C., & Barak, M. (2011) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-010-8250-y · Cited by 39
The role of gluten in multiple sclerosis: A systematic review
Thomsen, H. L., Jessen, E. B., Passali, M., & Frederiksen, J. L. (2018) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2018.10.019 · Cited by 38
Gluten neuropathy: prevalence of neuropathic pain and the role of gluten-free diet
Zis, P., Sarrigiannis, P. G., Rao, D. G., & Hadjivassiliou, M. (2018) · Journal of Neurology · doi:10.1007/s00415-018-8978-5 · Cited by 37
Self-citationNon-coeliac gluten sensitivity: A review of the literature
Henggeler, J. C., Veríssimo, M. T., & Ramos, F. (2017) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2017.05.018 · Cited by 36
Aquaporin 4 molecular mimicry and implications for neuromyelitis optica
Vaishnav, R. A., Liu, R., Chapman, J., Roberts, A. M., Ye, H., Rebolledo-Mendez, J. D., Tabira, T., Fitzpatrick, A. H., Achiron, A., Running, M. P., et al. (2013) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2013.04.015 · Cited by 36
Metadata
- Authors
- Hadjivassiliou, M., Sanders, D. S., Grünewald, R. A., Woodroofe, N., Boscolo, S., & Aeschlimann, D.
- Affiliations
- Royal Hallamshire Hospital (GB)
- University of Trieste (IT)
- Cardiff University (GB)
- Corresponding author
- Hadjivassiliou, Marios
- Venue
- The Lancet Neurology
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 9
- Issue
- 3
- Pages
- 318-330
- ISSN
- 1474-4422 (ISSN-L)
- OpenAlex
- W1992303087
- Cited by
- 404
- References
- 137
- Citations by year
- 2026: 16 · 2025: 18 · 2024: 16 · 2023: 15 · 2022: 15 · 2021: 24 · 2020: 21 · 2019: 21 · 2018: 17 · 2017: 29 · 2016: 23 · 2015: 37 · 2014: 39 · 2013: 30 · 2012: 36
- FWCI
- 5.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet Neurology (publishedVersion)
- PubMed (publishedVersion)
- SHURA (Sheffield Hallam University Research Archive) (Sheffield Hallam University) (submittedVersion)
- Funders
- Ryder Briggs Neuroscience Research Fund
- Topics
- Health Sciences › Medicine › Gastroenterology › Celiac Disease Research and Management
- Health Sciences › Medicine › Clinical Neurology › Autoimmune Neurological Disorders and Treatments
- Health Sciences › Medicine › Clinical Neurology › Peripheral Neuropathies and Disorders
- Keywords
- gluten sensitivity, celiac disease, neurological symptoms, autoimmune disease, pathophysiology, diagnosis
- MeSH terms
- Animals, Brain Diseases, Celiac Disease, Gastrointestinal Diseases, Glutens, Humans, Nervous System Diseases, Diet, Gluten-Free
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
