Ageing and multiple sclerosis

DNA methylation-based biomarkers and the epigenetic clock theory of ageing

Horvath, S., & Raj, K. (2018) · Nature Reviews Genetics · doi:10.1038/s41576-018-0004-3 · Cited by 3,095

Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis

Montalban, X., Hauser, S. L., Kappos, L., Arnold, D. L., Bar-Or, A., Comi, G., de Seze, J., Giovannoni, G., Hartung, H.-P., Hemmer, B., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1606468 · Cited by 1,905

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

Villeda, S. A., Luo, J., Mosher, K. I., Zou, B., Britschgi, M., Bieri, G., Stan, T. M., Fainberg, N., Ding, Z., Eggel, A., et al. (2011) · Nature · doi:10.1038/nature10357 · Cited by 1,763

Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection

Blackburn, E. H., Epel, E. S., & Lin, J. (2015) · Science · doi:10.1126/science.aab3389 · Cited by 1,596

Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology

Magliozzi, R., Howell, O. W., Vora, A., Serafini, B., Nicholas, R. S., Puopolo, M., Reynolds, R., & Aloisi, F. (2006) · Brain · doi:10.1093/brain/awm038 · Cited by 1,486

Microglial control of astrocytes in response to microbial metabolites

Rothhammer, V., Borucki, D. M., Tjon, E. C., Takenaka, M. C., Chao, C.-C., Ardura-Fabregat, A., de Lima, K. A., Gutiérrez-Vázquez, C., Hewson, P., Staszewski, O., et al. (2018) · Nature · doi:10.1038/s41586-018-0119-x · Cited by 1,051

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

Kappos, L., Bar-Or, A., Cree, B. A. C., Fox, R. J., Giovannoni, G., Gold, R., Vermersch, P., Arnold, D. L., Arnould, S., Scherz, T., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)30475-6 · Cited by 942

Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine

Haghikia, A., Jörg, S., Duscha, A., Berg, J., Manzel, A., Waschbisch, A., Hammer, A., Lee, D.-H., May, C., Wilck, N., et al. (2015) · Immunity · doi:10.1016/j.immuni.2015.09.007 · Cited by 927

Review: microglia of the aged brain: primed to be activated and resistant to regulation

Norden, D. M., & Godbout, J. P. (2013) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2012.01306.x · Cited by 792

A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis

Absinta, M., Maric, D., Gharagozloo, M., Garton, T., Smith, M. D., Jin, J., Fitzgerald, K. C., Song, A., Liu, P., Lin, J.-P., et al. (2021) · Nature · doi:10.1038/s41586-021-03892-7 · Cited by 768

Neuroinflammation: An astrocyte perspective

Lee, H., Lee, J.-H., Flausino, L. E., & Quintana, F. J. (2023) · Science Translational Medicine · doi:10.1126/scitranslmed.adi7828 · Cited by 253

Smouldering‐Associated Worsening in Multiple Sclerosis: An International Consensus Statement on Definition, Biology, Clinical Implications, and Future Directions

Scalfari, A., Traboulsee, A. L., Oh, J., Airas, L. M., Bittner, S., Calabrese, M., García‐Domínguez, J. M., Granziera, C., Greenberg, B. M., Hellwig, K., et al. (2024) · Annals of Neurology · doi:10.1002/ana.27034 · Cited by 107

Current and future role of MRI in the diagnosis and prognosis of multiple sclerosis

Rocca, M. A., Preziosa, P., Barkhof, F., Brownlee, W. J., Calabrese, M., Stefano, N. D., Granziera, C., Ropele, S., Toosy, A., Vidal‐Jordana, Á., et al. (2024) · The Lancet Regional Health - Europe · doi:10.1016/j.lanepe.2024.100978 · Cited by 94

Mechanosensitive Piezo1 channel in physiology and pathophysiology of the central nervous system

Zong, B., Yu, F., Zhang, X., Pang, Y., Zhao, W., Sun, P., & Li, L. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102026 · Cited by 82

Fabrication of MOF-based Nanozyme sensor arrays and their application in disease diagnosis

Wang, M., Zhang, H., Yan, S., Zhou, Y., Guo, X., An, D., Zhong, W., & Zhang, Y. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216506 · Cited by 79

Impact of aging on treatment considerations for multiple sclerosis patients

Macaron, G., Larochelle, C., Arbour, N., Galmard, M., Girard, M., Prat, A., & Duquette, P. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1197212 · Cited by 71

Senescent-like microglia limit remyelination through the senescence associated secretory phenotype

Gross, P. S., Durán-Laforet, V., Ho, L. T., Melchor, G. S., Zia, S., Manavi, Z., Barclay, W. E., Lee, S. H., Shults, N., Selva, S., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-57632-w · Cited by 62

Clinical Characteristics and Long-Term Outcomes of Late-Onset Multiple Sclerosis

Mouresan, E. F., Mentesidou, E., Berglund, A., McKay, K. A., Hillert, J. A., & Iacobaeus, E. (2024) · Neurology · doi:10.1212/wnl.0000000000208051 · Cited by 61

Increasing age of multiple sclerosis onset from 1920 to 2022: a population-based study

Habbestad, A., Willumsen, J. S., Aarseth, J. H., Grytten, N., Midgard, R., Wergeland, S., Myhr, K., & Torkildsen, Ø. (2023) · Journal of Neurology · doi:10.1007/s00415-023-12047-9 · Cited by 65

The ageing central nervous system in multiple sclerosis: the imaging perspective

Filippi, M., Preziosa, P., Barkhof, F., Ciccarelli, O., Cossarizza, A., Stefano, N. D., Gasperini, C., Geraldes, R., Granziera, C., Haider, L., et al. (2024) · Brain · doi:10.1093/brain/awae251 · Cited by 56

The Role of IL-6 in Neurodegenerative Disorders

Shan, C., Zhang, C., & Zhang, C. (2024) · Neurochemical Research · doi:10.1007/s11064-023-04085-6 · Cited by 52

The epigenetic modification of DNA methylation in neurological diseases

Li, L., Chen, R., Zhang, H., Li, J., Huang, H., Weng, J., Tan, H., Guo, T., Wang, M., & Xie, J. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1401962 · Cited by 54

Mechanisms of Demyelination and Remyelination Strategies for Multiple Sclerosis

Zhao, X., & Jacob, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076373 · Cited by 46

Integrating artificial intelligence with nanodiagnostics for early detection and precision management of neurodegenerative diseases

Hassan, Y. M., Wanas, A., Ali, A. A., & El-Sayed, W. M. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03719-x · Cited by 51

Discontinuation of First-Line Disease-Modifying Therapy in Patients With Stable Multiple Sclerosis

Coerver, E. M. E., Fung, W. H., de Beukelaar, J., Bouvy, W. H., Canta, L. R., Gerlach, O. H. H., Hoitsma, E., Hoogervorst, E. L. J., de Jong, B. A., Kalkers, N. F., et al. (2024) · JAMA Neurology · doi:10.1001/jamaneurol.2024.4164 · Cited by 43

Recent Advances in Aging and Immunosenescence: Mechanisms and Therapeutic Strategies

Wang, S., Huo, T., Lu, M., Zhao, Y., Zhang, J., He, W., & Chen, H. (2025) · Cells · doi:10.3390/cells14070499 · Cited by 47

Advancing multiple sclerosis management in older adults

van der Walt, A., Strijbis, E. M. M., Bridge, F., Coetzee, T., Graves, J., Brownlee, W. J., Butzkueven, H., Marrie, R. A., Hua, L. H., Lampe, A., et al. (2025) · Nature Reviews Neurology · doi:10.1038/s41582-025-01115-5 · Cited by 41

Comparing the Pathology, Clinical, and Demographic Characteristics of Younger and Older‐Onset Multiple Sclerosis

Knowles, S., Middleton, R., Cooze, B., Farkas, I., Leung, Y. Y., Allen, K., Winslade, M., Owen, D. R., Magliozzi, R., Reynolds, R., et al. (2023) · Annals of Neurology · doi:10.1002/ana.26843 · Cited by 39

Association Between Anti-CD20 Therapies and COVID-19 Severity Among Patients With Relapsing-Remitting and Progressive Multiple Sclerosis

Januel, É., Hajage, D., Labauge, P. M., Maillart, É., Seze, J. D., Zéphir, H., Pelletier, J., Guilloton, L., Bensa, C., Heinzlef, O., et al. (2023) · JAMA Network Open · doi:10.1001/jamanetworkopen.2023.19766 · Cited by 39

Physiological aging and inflammation-induced cellular senescence may contribute to oligodendroglial dysfunction in MS

Windener, F., Grewing, L., Thomas, C., Dorion, M., Otteken, M., Kular, L., Jagodic, M., Antel, J. P., Albrecht, S., & Kuhlmann, T. (2024) · Acta Neuropathologica · doi:10.1007/s00401-024-02733-x · Cited by 36

Efficacy and safety of mesenchymal stromal cell transplantation in the treatment of autoimmune and rheumatic immune diseases: a systematic review and meta-analysis of randomized controlled trials

Zeng, L., Liu, C., Wu, Y., Liu, S., Zheng, Y., Hao, W., Wang, D., & Sun, L. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04184-x · Cited by 37

Senolytic treatment diminishes microglia and decreases severity of experimental autoimmune encephalomyelitis

Drake, S., Zaman, A., Gianfelice, C., Hua, E. M.-L., Heale, K., Afanasiev, E., Klément, W., Stratton, J. A., Prat, A., Zandee, S., et al. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03278-2 · Cited by 38

Evaluation of Cell-Specific Epigenetic Age Acceleration in People With Multiple Sclerosis

Maltby, V. E., Xavier, A., Ewing, E., Campagna, M. P., Sampangi, S., Scott, R. J., Butzkueven, H., Jokubaitis, V., Kular, L., Bos, S. D., et al. (2023) · Neurology · doi:10.1212/wnl.0000000000207489 · Cited by 37

CCR5 and inflammatory storm

Lin, Y., Liu, S., Sun, Y., Chen, C., Yang, S., Pei, G., Lin, M., Yu, J., Liu, X., Wang, H., et al. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102286 · Cited by 33

CRISPR-edited human ES-derived oligodendrocyte progenitor cells improve remyelination in rodents

Wagstaff, L. J., Bestard-Cuche, N., Kaczmarek, M., Fidanza, A., McNeil, L., Franklin, R. J. M., & Williams, A. C. (2024) · Nature Communications · doi:10.1038/s41467-024-52444-w · Cited by 30

Disease-modifying therapies for Parkinson disease: lessons from multiple sclerosis

Kalia, L. V., Asis, A., Arbour, N., Bar‐Or, A., Bove, R. M., Luca, D. G. D., Fon, E. A., Fox, S. H., Gan‐Or, Z., Gommerman, J. L., et al. (2024) · Nature Reviews Neurology · doi:10.1038/s41582-024-01023-0 · Cited by 35

The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance

Doghish, A. S., Elazazy, O. E., Mohamed, H. H., Mansour, R. M., Ghanem, A., Faraag, A. H. I., Elballal, M. S., Elrebehy, M. A., Elesawy, A. E., Mageed, S. S. A., et al. (2023) · Pathology - Research and Practice · doi:10.1016/j.prp.2023.154880 · Cited by 23

Disability trajectories by progression independent of relapse activity status differ in pediatric, adult and late-onset multiple sclerosis

Simone, M., Lucisano, G., Guerra, T., Paolicelli, D., Rocca, M. A., Morra, V. B., Patti, F., Annovazzi, P. O. L., Gasperini, C., Luca, G. D., et al. (2024) · Journal of Neurology · doi:10.1007/s00415-024-12638-0 · Cited by 21

Disentangling Neurodegeneration From Aging in Multiple Sclerosis Using Deep Learning

Pontillo, G., Prados, F., Colman, J., Kanber, B., Abdel‐Mannan, O., Al‐Araji, S., Bellenberg, B., Bianchi, A., Bisecco, A., Brownlee, W. J., et al. (2024) · Neurology · doi:10.1212/wnl.0000000000209976 · Cited by 26

Immunosenescence in autoimmune diseases

Hu, H., Zhang, G., Chen, T., Liu, Y., Meng, L., Holmdahl, R., Dai, L., & Zhao, Y. C. (2025) · Autoimmunity Reviews · doi:10.1016/j.autrev.2025.103805 · Cited by 30

MS treatment de-escalation: review and commentary

Selmaj, K. W., Hartung, H., Mycko, M. P., Selmaj, I., & Cross, A. H. (2024) · Journal of Neurology · doi:10.1007/s00415-024-12584-x · Cited by 22

Association between age and inflammatory disease activity on magnetic resonance imaging in relapse onset multiple sclerosis during long‐term follow‐up

Coerver, E. M. E., Janssens, S., Ahmed, A., Wessels, M. H., van Kempen, Z. L. E., Jasperse, B., Barkhof, F., Koch, M. W., Mostert, J. P., Uitdehaag, B. M. J., et al. (2023) · European Journal of Neurology · doi:10.1111/ene.15862 · Cited by 22

Remyelination in animal models of multiple sclerosis: finding the elusive grail of regeneration

Packer, D., Fresenko, E. E., & Harrington, E. P. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1207007 · Cited by 21

Late-onset multiple sclerosis: disability trajectories in relapsing–remitting patients of the Italian MS Registry

Lorefice, L., Ferraro, O. E., Fenu, G., Amato, M. P., Morra, V. B., Conte, A., Luca, G. D., Ferraro, D., Filippi, M., Gazzola, P., et al. (2024) · Journal of Neurology · doi:10.1007/s00415-023-12152-9 · Cited by 22

Overview of emerging therapies for demyelinating diseases

Medina, R., Derias, A.-M., Lakdawala, M., Speakman, S., & Lucke-Wold, B. P. (2024) · World Journal of Clinical Cases · doi:10.12998/wjcc.v12.i30.6361 · Cited by 24

From pathogenesis to precision medicine: Targeting immune imbalance in multiple sclerosis

Pithakumar, A., Basha, S., Pai, A. R., & Mahato, K. K. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102921 · Cited by 19

Immunosenescence in aging and neurodegenerative diseases: evidence, key hallmarks, and therapeutic implications

Chen, Z., Mao, Z., Tang, W., Shi, Y., Liu, J., & You, Y. (2025) · Translational Neurodegeneration · doi:10.1186/s40035-025-00517-1 · Cited by 27

More than just a number: the gut microbiota and brain function across the extremes of life

Nuzum, N. D., Deady, C., Kittel‐Schneider, S., Cryan, J. F., O’Mahony, S. M., & Clarke, G. A. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2418988 · Cited by 22

Current state and perspectives of CAR T cell therapy in central nervous system diseases

Pfeffer, L. K., Fischbach, F., Heesen, C., & Friese, M. A. (2024) · Brain · doi:10.1093/brain/awae362 · Cited by 19

Accelerated Cellular Senescence in Progressive Multiple Sclerosis: A Histopathological Study

Papadopoulos, D., Magliozzi, R., Bandiera, S., Cimignolo, I., Barusolo, E., Probert, L., Gorgoulis, V. G., Reynolds, R., & Nicholas, R. S. (2025) · Annals of Neurology · doi:10.1002/ana.27195 · Cited by 19

Microglia in Brain Aging and Age-Related Diseases: Friends or Foes?

Ishikawa, K., Fujikawa, R., Okita, K., Kimura, F., Watanabe, T., Katsurabayashi, S., & Iwasaki, K. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262311494 · Cited by 18

Menopausal transition in multiple sclerosis: relationship with disease activity and brain volume measurements

Lorefice, L., Fenu, G., Fronza, M., Murgia, F., Frau, J., Coghe, G., Barracciu, M. A., Atzori, L., Angioni, S. L., & Cocco, E. E. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1251667 · Cited by 19

Old and New Strategies in the Treatment of Pediatric Multiple Sclerosis: A Personal View for a New Treatment Approach

Ghezzi, A. (2024) · Neurology and Therapy · doi:10.1007/s40120-024-00633-6 · Cited by 17

BCAS1-positive oligodendrocytes enable efficient cortical remyelination in multiple sclerosis

Bergner, C. G., van der Meer, F., Franz, J., Vakrakou, A., Würfel, T., Nessler, S., Schäfer, L., Nau-Gietz, C., Winkler, A., Lagumersindez-Denis, N., et al. (2025) · Brain · doi:10.1093/brain/awae293 · Cited by 16

Aging is associated with reduced inflammatory disease activity independent of disease duration in relapsing multiple sclerosis trial populations

Coerver, E. M. E., Kaçar, S., Ciccarelli, O., Sormani, M. P., Barkhof, F., Arnold, D. L., Schoonheim, M. M., van Kempen, Z. L. E., Mostert, J. P., Koch, M. W., et al. (2024) · Multiple Sclerosis Journal · doi:10.1177/13524585241272938 · Cited by 18

G-protein coupled receptors in neuroinflammation, neuropharmacology, and therapeutics

Singh, A. P., Shadangi, S., & Rana, S. (2025) · Biochemical Pharmacology · doi:10.1016/j.bcp.2025.117301 · Cited by 16

Microglia activation in periplaque white matter in multiple sclerosis depends on age and lesion type, but does not correlate with oligodendroglial loss

Kessler, W., Thomas, C., & Kuhlmann, T. (2023) · Acta Neuropathologica · doi:10.1007/s00401-023-02645-2 · Cited by 17

The molecular effects underlying the pharmacological activities of daphnetin

Wei, Z., Wei, N., Su, L., & Gao, S. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1407010 · Cited by 17

A Window into New Insights on Progression Independent of Relapse Activity in Multiple Sclerosis: Role of Therapies and Current Perspective

Guerra, T., & Iaffaldano, P. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26030884 · Cited by 15

Frailty in multiple sclerosis: A scoping review

Worikat, N. A., Molaei, F., Zanotto, A., Tabatabaei, A., LYNCH, S. G., Troen, B. R., Sosnoff, J. J., & Zanotto, T. (2024) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2024.106157 · Cited by 14

The influence of menopause on multiple sclerosis

Simonsen, C. S., Flemmen, H. Ø., Broch, L., Myklebust, H., Berg‐Hansen, P., Brunborg, C., & Celius, E. G. (2024) · European Journal of Neurology · doi:10.1111/ene.16566 · Cited by 15

Senescence marker p16INK4a expression in patients with multiple sclerosis

Yang, J. H., Miner, A. E., Fair, A. E., Kinkel, R. P., & Graves, J. S. (2024) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2024.105498 · Cited by 13

Ocrelizumab use in multiple sclerosis: a real-world experience in a changing therapeutic scenario

Lorefice, L., Mellino, P., Frau, J., Coghe, G., Fenu, G., & Cocco, E. E. (2024) · Neurological Sciences · doi:10.1007/s10072-024-07449-0 · Cited by 14

Menopause Impact on Multiple Sclerosis Disability Progression

Bridge, F., Sanfilippo, P. G., Zhu, C., Skibina, O. G., Nguyen, A., Kalinčík, T., Buzzard, K. A., Taylor, B. V., Macintyre, J., Hall, L., et al. (2025) · JAMA Neurology · doi:10.1001/jamaneurol.2025.3538 · Cited by 12

Clinical and demographic characteristics of late-onset multiple sclerosis: LOMS-TR study

Sıvacı, A. Ö., Seferoğlu, M., Çınar, B. P., Uzunköprü, C., Beckmann, Y. Y., Doğan, İ. G., Tezer, D. Ç., Tunç, A., Ethemoğlu, Ö., Gümüş, H., et al. (2024) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2024.105469 · Cited by 13

Hospital‐Treated Infections and Risk of Disability Worsening in Multiple Sclerosis

Hu, Y., Frisell, T., Alping, P., Song, H., Yudi Pawitan, Y., Fang, F., & Piehl, F. (2024) · Annals of Neurology · doi:10.1002/ana.27026 · Cited by 12

Cellular Senescence in Glial Cells: Implications for Multiple Sclerosis

Maupin, E. A., & Adams, K. L. (2025) · Journal of Neurochemistry · doi:10.1111/jnc.16301 · Cited by 12

Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021

Guo, X., Liu, X., Lin, J., Huang, Z., Lin, S., Zhang, M., Xu, Z., & Lin, X. (2025) · Frontiers in Public Health · doi:10.3389/fpubh.2025.1561216 · Cited by 13

Risk of cervical pre-cancer and cancer in women with multiple sclerosis exposed to high efficacy disease modifying therapies

Bridge, F., Brotherton, J. M. L., Foong, Y. C., Butzkueven, H., Jokubaitis, V., & van der Walt, A. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1119660 · Cited by 14

Effectiveness of Disease-Modifying Therapies in Patients With Late-Onset Relapsing-Remitting Multiple Sclerosis

Al‐Araji, S., Moccia, M., Jha, A., Zhang, L., Eshaghi, A., Kanber, B., Bianchi, A., Yam, C., Abdel‐Mannan, O., Goodkin, O., et al. (2025) · Neurology · doi:10.1212/wnl.0000000000213967 · Cited by 14

The regulation of microglia by aging and autophagy in multiple sclerosis

Wang, X., Sun, Y., Yu, H., Xue, C., Pei, X., Chen, Y., & Guan, Y. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107786 · Cited by 11

The 2024 McDonald criteria show comparable sensitivity to previous criteria for late-onset multiple sclerosis

Tena‐Cucala, R., Naval‐Baudin, P., Martínez-Yélamos, A., León, I., Muñoz‐Vendrell, A., Bau, L., Matas, E., Arroyo-Pereiro, P., Puchades, A. C., Morandeira, F., et al. (2025) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2025.106658 · Cited by 11

Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives

Zhang, Q., & Sun, D. B. (2025) · Advanced Science · doi:10.1002/advs.202516592 · Cited by 15

As time goes by: Treatment challenges in elderly people with multiple sclerosis

Gelibter, S., Saraceno, L., Pirro, F., Susani, E. L., & Protti, A. (2024) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2024.578368 · Cited by 13

Brain and cervical spinal cord MRI correlates of sensorimotor impairment in patients with multiple sclerosis

Morozumi, T., Preziosa, P., Meani, A., Pessina, G., Pagani, E., Azzimonti, M., Filippi, M., & Rocca, M. A. (2024) · Multiple Sclerosis Journal · doi:10.1177/13524585241260145 · Cited by 10

Sbno1 mediates cell–cell communication between neural stem cells and microglia through small extracellular vesicles

Zhang, Y., Zhu, Z., Li, Z., Feng, J., Long, J., Deng, Y., Ahmed, W., Khan, A. A., Huang, S., Fu, Q., et al. (2024) · Cell & Bioscience · doi:10.1186/s13578-024-01296-4 · Cited by 10

Are highly active and aggressive multiple sclerosis the same entity?

Correale, J. D., Rush, C., & Barboza, A. G. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1132170 · Cited by 10

Genetically Determined Levels of mTOR-Dependent Circulating Proteins and Risk of Multiple Sclerosis

Zhang, Y., Fan, K., Wang, Q., Hu, J.-X., Wang, Q., Zhang, H., Song, S., Zhao, R., Qiao, J., & Zhang, S. (2023) · Neurology and Therapy · doi:10.1007/s40120-023-00455-y · Cited by 11

Interpretable and Intuitive Machine Learning Approaches for Predicting Disability Progression in Relapsing-Remitting Multiple Sclerosis Based on Clinical and Gray Matter Atrophy Indicators

Yan, Z., Shi, Z., Zhu, Q., Feng, J., Liu, Y., Li, Y., Zhou, F., Zhuo, Z., Ding, S., Wang, X., et al. (2024) · Academic Radiology · doi:10.1016/j.acra.2024.01.032 · Cited by 10

BrainAgeNeXt: Advancing brain age modeling for individuals with multiple sclerosis

Rosa, F. L., Silva, J. D. S., Dereskewicz, E., Invernizzi, A., Cahan, N., Galasso, J., Garcia, N., Graney, R., Levy, S. A., Verma, G., et al. (2025) · Imaging Neuroscience · doi:10.1162/imag_a_00487 · Cited by 9

Use of Disease-Modifying Therapies in Patients With Late-Onset Multiple Sclerosis

Robin, C., Rollot, F., Lefort, M., Casey, R., Vukusic, S., Mathey, G., Ciron, J., Seze, J. D., Stankoff, B., Maillart, É., et al. (2025) · Neurology · doi:10.1212/wnl.0000000000213744 · Cited by 12

Refining Prognostic Factors in Adult-Onset Multiple Sclerosis: A Narrative Review of Current Insights

Guerra, T., Copetti, M., Achille, M., Ferri, C., Simone, M., D’Alfonso, S., Pugliatti, M., & Iaffaldano, P. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26167756 · Cited by 9

Oligodendrocyte precursor cell-specific blocking of low-glucose-induced activation of AMPK ensures myelination and remyelination

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Accelerated metabolomic aging and its association with social determinants of health in multiple sclerosis

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