Effect of Ramadan fasting on some indices of insulin resistance and components of the metabolic syndrome in healthy male adults
Open accessAbstract
The purpose of the present study was to evaluate the effect of Ramadan fasting on insulin sensitivity in subjects with the metabolic syndrome. Males (n 55; age 34·1 (sd 8·9) years) with the metabolic syndrome were studied. Blood pressure, waist circumference, body weight, HDL-cholesterol (HDL-C), TAG, fasting plasma glucose (FPG), fasting blood insulin and insulin resistance indices (quantitative insulin sensitivity check index (QUICKI), homeostasis model assessment of insulin resistance (HOMA-IR) and reciprocal index of HOMA-IR (1/HOMA-IR)) were evaluated before and after 30 d of Ramadan fasting (two meals at 12 h intervals). The dietary intake was estimated by 24 h recall before and after fasting. The total daily energy intake was decreased by 234·6 (sd 88·2) kJ/d in the fasting period (P = 0·005). 1/HOMA-IR, QUICKI and HDL-C were significantly increased (P = 0·005, P = 0·001 and P = 0·004) and FPG significantly decreased (P < 0·005) after fasting. Simple linear regression analysis demonstrated that HOMA-IR, 1/HOMA-IR and QUICKI were related to waist circumference after intervention (r 0·458, P < 0·001; r − 0·396, P < 0·05; r − 0·342, P < 0·05). In conclusion, the present study showed that the combined change in the number and timing of meals and portioning of the entire intake into only two meals per d may increase insulin sensitivity in subjects with the metabolic syndrome even when the decrease in energy consumption is minimal.
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In the Islamic month of Ramadan, meal timing is restricted to the hours between sunrise and sunset for 1 month.
“in the Islamic month of Ramadan, meal timing is restricted to the hours between sunrise and sunset for 1 month (181).”
From Meal timing and its role in obesity and associated diseases (2024) · cites this paper as [181]
The Subjects and methods passage describes a 30-day period of abstaining from food between sunrise and sunset. It says participants ate before sunrise and after sunset—the opposite of the claimed meal timing. (LLM, conf=0.90)
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Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502 · see citing works
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944 · see citing works
Expert Panel on Detection, E. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.19.2486 · Cited by 26,011 · see citing works
Ford, E. S., Giles, W. H., & Dietz, W. H. (2002) · JAMA · doi:10.1001/jama.287.3.356 · Cited by 6,698 · see citing works
Katz, A., Nambi, S. S., Mather, K., Baron, A. D., Follmann, D. A., Sullivan, G., & Quon, M. J. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.7.6661 · Cited by 3,831 · cited 1× · see citing works
“((15)), with the formula QUICKI 1⁄4 1/(log (FIRI in mU/ml) þ log (FPG in mg/dl)).”
BackgroundEsposito, K., Marfella, R., Ciotola, M., Di Palo, C., Giugliano, F., Giugliano, G., D'Armiento, M., D'Andrea, F., & Giugliano, D. (2004) · JAMA · doi:10.1001/jama.292.12.1440 · Cited by 2,126 · see citing works
Increasing Prevalence of the Metabolic Syndrome Among U.S. Adults
Ford, E. S., Giles, W. H., & Mokdad, A. H. (2004) · Diabetes Care · doi:10.2337/diacare.27.10.2444 · Cited by 1,488 · see citing works
Yeni-Komshian, H., Carantoni, M., Abbasi, F., & Reaven, G. M. (2000) · Diabetes Care · doi:10.2337/diacare.23.2.171 · Cited by 414 · see citing works
Saad, M. F., Anderson, R. L., Laws, A., Watanabe, R. M., Kades, W. W., Chen, Y. D. I., Sands, R. E., Pei, D., Savage, P. J., & Bergman, R. N. (1994) · Diabetes · doi:10.2337/diab.43.9.1114 · Cited by 376 · see citing works
Heymsfield, S. B., Segal, K. R., Hauptman, J., Lucas, C. P., Boldrin, M. N., Rissanen, A., Wilding, J. P. H., & Sjöström, L. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.9.1321 · Cited by 358 · see citing works
The changes of metabolic profile and weight during Ramadan fasting.
Ziaee, V., Razaei, M., Ahmadinejad, Z., shaikh, H. A., Yousefi, R., Yarmohammadi, L., Bozorgi, F., & Behjati, M. (2006) · PubMed · Cited by 307 · see citing works
Pathophysiology of insulin resistance
Sesti, G. (2006) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2006.09.007 · Cited by 289 · see citing works
Chen, H., Sullivan, G., & Quon, M. J. (2005) · Diabetes · doi:10.2337/diabetes.54.7.1914 · Cited by 270 · see citing works
Bogdan, A., Bouchareb, B., & Touitou, Y. (2001) · Life Sciences · doi:10.1016/s0024-3205(01)00966-3 · Cited by 225 · see citing works
Yokoyama, H., Emoto, M., Fujiwara, S., Motoyama, K., Morioka, T., Komatsu, M., Tahara, H., Shoji, T., Okuno, Y., & Nishizawà, Y. (2003) · Diabetes Care · doi:10.2337/diacare.26.8.2426 · Cited by 212 · see citing works
Anderson, R. L., Hamman, R. F., Savage, P. J., Saad, M. F., Laws, A., Kades, W. W., Sands, R., & Cefalu, W. T. (1995) · American Journal of Epidemiology · doi:10.1093/aje/142.7.724 · Cited by 138 · see citing works
Richelsen, B., & Pedersen, S. B. (1995) · PubMed · Cited by 103 · see citing works
Ferrara, C. M., & Goldberg, A. P. (2001) · Diabetes Care · doi:10.2337/diacare.24.2.245 · Cited by 101 · see citing works
Metabolic and clinical effects of Ramadan fasting in patients with type II diabetes.
Yarahmadi, S. H., Larijani, B. A., Bastanhagh, M., et al. (2003) · PubMed · Cited by 85 · see citing works
The effect of Ramadan fasting on fasting serum glucose in healthy adults.
Larijani, B. A., Zahedi, F., Sanjari, M., et al. (2003) · PubMed · Cited by 81 · see citing works
Interactions between leptin, neuropeptide-Y and insulin with chronic diurnal fasting during Ramadan
Kassab, S. E., Abdul‐Ghaffar, T., Nagalla, D. S., Sachdeva, U., & Nayar, U. (2004) · Annals of Saudi Medicine · doi:10.5144/0256-4947.2004.345 · Cited by 57 · see citing works
Circadian Timing of Single Daily "Meal" Affects Survival of Mice
Nelson, W. W., Cadotte, L., & Halberg, F. (1973) · Experimental Biology and Medicine · doi:10.3181/00379727-144-37678 · Cited by 53 · see citing works
La pratique du jeûne du mois de Ramadan chez le diabétique de type 2
Bouguerra, R., Jabrane, J., Maâtki, C., Salem, L. B., Hamzaoui, J., Kadhi, A. E., Rayana, C. B., & Slama, C. B. (2006) · Annales d Endocrinologie · doi:10.1016/s0003-4266(06)72541-0 · Cited by 47 · see citing works
Minehira, K., & Tappy, L. (2002) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601645 · Cited by 43 · see citing works
The Escalating Pandemics of Obesity and Sedentary Lifestyle
Manson, J. E., Skerrett, P. J., Greenland, P., & VanItallie, T. B. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.3.249 · Cited by 32 · see citing works
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Fasting: molecular mechanisms and clinical applications
Longo, V. D., & Mattson, M. P. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2013.12.008 · Cited by 1,425 · see citing works
St-Onge, M.-P., Ard, J., Baskin, M. L., Chiuve, S. E., Johnson, H. M., Kris-Etherton, P., & Varady, K. (2017) · Circulation · doi:10.1161/cir.0000000000000476 · Cited by 728 · see citing works
Timing of food intake: identifying contributing factors to design effective interventions
Dashti, H. S., Scheer, F. A. J. L., Saxena, R., & Garaulet, M. (2019) · Advances in Nutrition · doi:10.1093/advances/nmy131 · Cited by 121 · see citing works
Domaszewski, P., Konieczny, M., Pakosz, P., Bączkowicz, D., & Sadowska-Krępa, E. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17114138 · Cited by 80 · see citing works
Meal timing and its role in obesity and associated diseases
Peters, B., Vahlhaus, J., & Pivovarova-Ramich, O. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1359772 · Cited by 72 · see citing works
“Tradition and religion have been shown to in fl uence meal timing throughout history as well as recently; for example, in the Islamic month of Ramadan, meal timing is restricted to the hours between sunrise and sunset for 1 month (181).”
BackgroundEfficacy of fasting calorie restriction on quality of life among aging men
Teng, N. I. M. F., Shahar, S., Manaf, Z. A., Das, S. K., Taha, C. S. C., & Ngah, W. Z. W. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.07.007 · Cited by 67 · see citing works
- Authors
- Shariatpanahi, Z. V., Shariatpanahi, M. V., Shahbazi, S., Hossaini, A., & Abadi, A.
- Affiliations
- Shahid Beheshti University (IR)
- Islamic Azad University, Tehran (IR)
- Iran University of Medical Sciences (IR)
- Corresponding author
- Shariatpanahi, Z. Vahdat
- Venue
- British Journal of Nutrition
- Publisher
- Cambridge University Press (CUP)
- Published
- 2008-07
- Volume
- 100
- Issue
- 1
- Pages
- 147-151
- ISSN
- 0007-1145 (ISSN-L)
- 1475-2662
- OpenAlex
- W2150475051
- Cited by
- 101
- References
- 25
- Citations by year
- 2026: 1 · 2025: 10 · 2024: 4 · 2023: 4 · 2022: 5 · 2021: 8 · 2020: 12 · 2019: 5 · 2018: 6 · 2017: 5 · 2016: 2 · 2015: 7 · 2014: 12 · 2013: 4 · 2012: 7
- FWCI
- 0.89
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- British Journal Of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Dietary Effects on Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Keywords
- Ramadan fasting, insulin resistance, metabolic syndrome, insulin sensitivity, HOMA-IR, QUICKI, fasting blood glucose, HDL cholesterol, waist circumference, energy intake, meal timing
- MeSH terms
- Adult, Blood Glucose, Blood Pressure, Energy Intake, Fasting, Homeostasis, Humans, Insulin Resistance, Islam, Cholesterol, HDL, Male, Middle Aged, Religion and Medicine, Metabolic Syndrome, Waist Circumference
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