Efficacy of fasting calorie restriction on quality of life among aging men
Abstract
Calorie restriction (CR) has been promoted to increase longevity. Previous studies have indicated that CR can negatively affect mood and therefore the effect of CR on mood and quality of life (QOL) becomes crucial when considering the feasibility of CR in humans. We conducted a three month clinical trial on CR (reduction of 300 to 500 kcal/day) combined with two days/week of Muslim sunnah fasting (FCR) to determine the effectiveness of FCR on QOL among aging men in Klang Valley, Malaysia. A total of 25 healthy Malay men (age 58.8±5.1 years), with no chronic diseases and a BMI of 23.0 to 29.9 kg/m2 were randomized to FCR (n=12) and control (n=13) groups. Body composition measurements and QOL questionnaires were ascertained at baseline, week 6 and week 12. QOL was measured using the Short-Form 36, sleep quality was determined using the Pittsburgh Sleep Quality Index, the Beck Depression Inventory II was used to measure mood and the Perceived Stress Scale was used to measure depression. The FCR group had a significant reduction in body weight, BMI, body fat percentage and depression (P<0.05). The energy component of QOL was significantly increased in FCR group (p<0.05). There were no significant changes in sleep quality and stress level between the groups as a result of the intervention. In conclusion, FCR resulted in body weight and fat loss and alleviated depression with some improvement in the QOL in our study and has the potential to be implemented on a wider scale.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Aged men on an eating plan involving 2 days of fasting each week lose weight and experienced fewer bouts of depression.
“Similarly, aged men on an eating plan involving 2 days of fasting each week lose weight and experienced fewer bouts of depression (Teng et al., 2011).”
From The Search for Antiaging Interventions: From Elixirs to Fasting Regimens (2014) · cites this paper as Teng et al., 2011
Cites
The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research
Buysse, D. J., Reynolds, C. F., Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90047-4 · Cited by 35,234 · see citing works
A Global Measure of Perceived Stress
Cohen, S., Kamarck, T., & Mermelstein, R. (1983) · Journal of Health and Social Behavior · doi:10.2307/2136404 · Cited by 32,807 · see citing works
SF-36 health survey: Manual and interpretation guide
Ware, J. (2003) · Medical Entomology and Zoology · Cited by 11,424 · see citing works
The Whoqol Group (1998) · Social Science & Medicine · doi:10.1016/s0277-9536(98)00009-4 · Cited by 3,802 · see citing works
THE BIOLOGY OF HUMAN STARVATION
Keys, A., BROŽEK, J., & Henschel, A. (1951) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1951.tb56499.x · Cited by 2,053 · see citing works
Heilbronn, L. K., de Jonge, L., Frisard, M. I., DeLany, J. P., Larson-Meyer, D. E., Rood, J., Nguyen, T., Martin, C. K., Volaufova, J., Most, M. M., et al. (2006) · JAMA · doi:10.1001/jama.295.13.1539 · Cited by 969 · see citing works
Caloric restriction improves memory in elderly humans
Witte, A. V., Fobker, M., Gellner, R., Knecht, S., & Flöel, A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808587106 · Cited by 574 · see citing works
Larson-Meyer, D. E., Heilbronn, L. K., Redman, L. M., Newcomer, B. R., Frisard, M. I., Anton, S., Smith, S. R., Alfonso, A., Ravussin, E., & the Pennington CALERIE Team (2006) · Diabetes Care · doi:10.2337/dc05-2565 · Cited by 504 · see citing works
The impact of religious fasting on human health
Trepanowski, J. F., & Bloomer, R. J. (2010) · Nutrition Journal · doi:10.1186/1475-2891-9-57 · Cited by 435 · see citing works
BLACK, A. E., Prentice, A. M., Goldberg, G. R., Jebb, S. A., Bingham, S. A., Livingstone, M. B. E., & Coward, A. (1993) · Journal of the American Dietetic Association · doi:10.1016/0002-8223(93)91820-g · Cited by 414 · see citing works
Caloric restriction and intermittent fasting: Two potential diets for successful brain aging
Martin, B., Mattson, M. P., & Maudsley, S. R. (2006) · Ageing Research Reviews · doi:10.1016/j.arr.2006.04.002 · Cited by 394 · see citing works
Heilbronn, L. K., Smith, S. R., Martin, C. K., Anton, S. D., & Ravussin, E. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.69 · Cited by 393 · see citing works
Alternate-day fasting and chronic disease prevention: a review of human and animal trials
Varady, K. A., & Hellerstein, M. K. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.1.7 · Cited by 358 · see citing works
The changes of metabolic profile and weight during Ramadan fasting.
Ziaee, V., Razaei, M., Ahmadinejad, Z., shaikh, H. A., Yousefi, R., Yarmohammadi, L., Bozorgi, F., & Behjati, M. (2006) · PubMed · Cited by 307 · see citing works
Effect of Calorie Restriction with or without Exercise on Body Composition and Fat Distribution
Redman, L. M., Heilbronn, L. K., Martin, C. K., Alfonso, A., Smith, S. R., Ravussin, E., & for the Pennington CALERIE Team (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2184 · Cited by 293 · see citing works
Estimating under-reporting of energy intake in dietary surveys using an individualised method
Rennie, K. L., Coward, A. W., & Jebb, S. A. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507433086 · Cited by 262 · see citing works
Caloric restriction in humans: Potential pitfalls and health concerns
Dirks, A. J., & Leeuwenburgh, C. (2005) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2005.09.001 · Cited by 239 · see citing works
Racette, S. B., Weiss, E. P., Villareal, D. T., Arif, H., Steger-May, K., Schechtman, K. B., Fontana, L., Klein, S., & Holloszy, J. O. (2006) · The Journals of Gerontology: Series A · doi:10.1093/gerona/61.9.943 · Cited by 237 · see citing works
Techniques for the measurement of human energy expenditure: a practical guide.
Murgatroyd, P. R., Shetty, P. S., & Prentice, A. M. (1993) · PubMed · Cited by 128 · see citing works
Ibrahim, W. H., Habib, H. M., Jarrar, A. H., & Baz, S. A. A. (2008) · Annals of Nutrition and Metabolism · doi:10.1159/000172979 · Cited by 126 · see citing works
Relation between body weight and health-related quality of life among the elderly in Spain
López‐García, E., Banegas, J. R., Gutiérrez-Fisac, J. L., Pérez-Regadera, A. G., Díez‐Gañán, L., & Rodríguez‐Artalejo, F. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.0802275 · Cited by 125 · see citing works
Research in Islamic Fasting and Health
Azizi, F. (2002) · Annals of Saudi Medicine · doi:10.5144/0256-4947.2002.186 · Cited by 117 · see citing works
Redman, L. M., Martin, C. K., Williamson, D. A., & Ravussin, É. (2008) · Physiology & Behavior · doi:10.1016/j.physbeh.2008.04.017 · Cited by 109 · see citing works
Shariatpanahi, Z. V., Shariatpanahi, M. V., Shahbazi, S., Hossaini, A., & Abadi, A. (2008) · British Journal of Nutrition · doi:10.1017/s000711450787231x · Cited by 101 · see citing works
Appetite Changes Under Free-living Conditions During Ramadan Fasting
Finch, G. M., Day, J. E. L., Razak, et al. (1998) · Appetite · doi:10.1006/appe.1998.0164 · Cited by 92 · see citing works
The Biology of Human Starvation
Tobey, J. A. (1951) · American Journal of Public Health and the Nations Health · doi:10.2105/ajph.41.2.236-b · Cited by 89 · see citing works
Effect of Ramadan Fasting on Clinical and Biochemical Parameters in Healthy Adults
Fakhrzadeh, H., Lariiani, B., Sanjari, M., Baradar-Jalili, R., & Amini, M. R. (2003) · Annals of Saudi Medicine · doi:10.5144/0256-4947.2003.223 · Cited by 87 · see citing works
Shahar, S., Earland, J., & Abdulrahman, S. (2000) · PubMed · Cited by 84 · see citing works
Self-citationEnergy and Nutrient Intakes: Findings from the Malaysian Adult Nutrition Survey (MANS).
Mirnalini, K., Zalilah, M. S., Safiah, M. Y., Tahir, A., Haslinda, M. D. S., Siti Rohana, D., My, K. Z., Hasyami, S. M., & Normah, H. (2008) · PubMed · Cited by 76 · see citing works
Weight loss and health-related quality of life: Results at 1-year follow-up
Fontaine, K. R., Barofsky, I., Bartlett, S. J., et al. (2003) · Eating Behaviors · doi:10.1016/s1471-0153(03)00059-x · Cited by 70 · see citing works
Effects of Ramadan Fasting on the Health of Muslims.
Toda, M., & Morimoto, K. (2000) · Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) · doi:10.1265/jjh.54.592 · Cited by 39 · see citing works
Bluck, L. J. C. (2008) · Nutrition Bulletin · doi:10.1111/j.1467-3010.2008.00695.x · Cited by 30 · see citing works
Neovius, M., Uddén, J., & Hemmingsson, E. (2007) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181579.38a · Cited by 28 · see citing works
Islamic Fasting: An Effective Strategy for Prevention and Control of Obesity
Khan, A., & ., M. M. A. K. (2002) · Pakistan Journal of Nutrition · doi:10.3923/pjn.2002.185.187 · Cited by 26 · see citing works
Srapyan, Z., Armenian, H. K., & Petrosyan, V. (2006) · Age and Ageing · doi:10.1093/ageing/afj039 · Cited by 20 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Fasting: molecular mechanisms and clinical applications
Longo, V. D., & Mattson, M. P. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2013.12.008 · Cited by 1,425 · see citing works
Effects of intermittent fasting on body composition and clinical health markers in humans
Tinsley, G. M., & La Bounty, P. M. (2015) · Nutrition Reviews · doi:10.1093/nutrit/nuv041 · Cited by 382 · see citing works
The Search for Antiaging Interventions: From Elixirs to Fasting Regimens
de Cabo, R., Carmona-Gutierrez, D., Bernier, M., Hall, M. N., & Madeo, F. (2014) · Cell · doi:10.1016/j.cell.2014.05.031 · Cited by 345 · see citing works
Harris, L., Hamilton, S., Azevedo, L. B., Olajide, J., De Brún, C., Waller, G., Whittaker, V., Sharp, T., Lean, M., Hankey, C., et al. (2018) · JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2016-003248 · Cited by 319 · see citing works
Seimon, R. V., Roekenes, J. A., Zibellini, J., Zhu, B., Gibson, A. A., Hills, A. P., Wood, R. E., King, N. A., Byrne, N. M., & Sainsbury, A. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.09.014 · Cited by 202 · see citing works
“16 of lean and overweight participants (51, 54-56, 59) and 3 included lean participants only (53, 57, 302 58).”
BackgroundInfluentialYao, K., Su, H., Cui, K., Gao, Y., Xu, D., Wang, Q., Ha, Z., Zhang, T., Chen, S., & Liu, T. (2024) · The Journal of nutrition, health and aging · doi:10.1016/j.jnha.2024.100165 · Cited by 25 · see citing works
- Authors
- Teng, N. I. M. F., Shahar, S., Manaf, Z. A., Das, S. K., Taha, C. S. C., & Ngah, W. Z. W.
- Affiliations
- National University of Malaysia (MY)
- Tufts University (US)
- ORCID
- Venue
- Physiology & Behavior
- Publisher
- Elsevier BV
- Published
- 2011-10
- Volume
- 104
- Issue
- 5
- Pages
- 1059-1064
- ISSN
- 0031-9384 (ISSN-L)
- OpenAlex
- W1992606502
- Cited by
- 67
- References
- 35
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 5 · 2023: 7 · 2022: 6 · 2021: 7 · 2020: 8 · 2019: 1 · 2018: 6 · 2017: 5 · 2016: 4 · 2015: 4 · 2014: 4 · 2013: 6
- FWCI
- 2.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Physiology & Behavior (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Universiti Kebangsaan Malaysia (UKM-AP-TKP-09-2009)
- Topics
- Health Sciences › Medicine › Physiology › Dietary Effects on Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Keywords
- quality of life, older men, depression, weight loss, fat loss, sleep quality, perceived stress, mood, longevity
- MeSH terms
- Aged, Aging, Analysis of Variance, Body Composition, Body Weight, Fasting, Humans, Male, Middle Aged, Quality of Life, Body Mass Index, Caloric Restriction
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review