Diet and risk of endometriosis in a population-based case–control study
Open accessAbstract
Diet plausibly has a role in the aetiology of endometriosis through effects on steroid hormone levels; however, few published studies have examined the diet and endometriosis risk. We evaluated dietary risk factors for endometriosis in a population-based case–control study. Cases were 284 Group Health (GH) enrollees aged 18–49 years with newly diagnosed, surgically confirmed endometriosis between 1996 and 2001. Controls were 660 randomly selected age-matched female GH enrollees without a history of endometriosis. Nutrients and selected food groups were assessed using the Women's Health Initiative FFQ. OR of endometriosis risk associated with dietary exposures were estimated using unconditional logistic regression and adjusted for identified covariates. Increased total fat consumption was associated with decreased endometriosis risk (fourth quartile v.lowest: OR 0·5, 95 % CI 0·2, 1·0,P-trend = 0·12). Increased β-carotene consumption and servings/d of fruit were associated with increased risk (β-carotene third quartile v.lowest: OR 1·7, 95 % CI 1·1, 2·6; fourth quartile v.lowest: OR 1·6, 95 % CI 1·0, 2·5,P-trend 0·16; fruit >2 servings/d v.< 1: OR 1·5, 95 % CI 1·0, 2·3,P-trend = 0·04). We also found a suggestion of decreased endometriosis risk associated with the consumption of dairy products (2 servings/d v.≤ 1: OR 0·6, >2 servings/d v.≤ 1: OR 0·7), but this association was not statistically significant for the highest tertile. The present study suggests that specific dietary components may be associated with endometriosis risk.
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The results indicate that specific dietary components may be associated with endometriosis risk.
“The results indicate that specific dietary components may be associated with endometriosis risk.”
From Defining Future Directions for Endometriosis Research: Workshop Report From the 2011 World Congress of Endometriosis in Montpellier, France (2013) · cites this paper as [53]
A recent study evaluated dietary risk factors for endometriosis in a population-based case-control study.
“A recent study evaluated dietary risk factors for endometriosis in a population-based case-control study.53”
From Defining Future Directions for Endometriosis Research: Workshop Report From the 2011 World Congress of Endometriosis in Montpellier, France (2013) · cites this paper as [53]
Increased total fat consumption was associated with decreased endometriosis risk and increased b-carotene consumption and servings of fruit were associated with increased risk.
“Increased total fat consumption was associated with decreased endometriosis risk and increased b-carotene consumption and servings of fruit were associated with increased risk.”
From Defining Future Directions for Endometriosis Research: Workshop Report From the 2011 World Congress of Endometriosis in Montpellier, France (2013) · cites this paper as [53]
There was also a suggestion of decreased endometriosis risk associated with the consumption of dairy products.
“There was also a suggestion of decreased endometriosis risk associated with the consumption of dairy products.”
From Defining Future Directions for Endometriosis Research: Workshop Report From the 2011 World Congress of Endometriosis in Montpellier, France (2013) · cites this paper as [53]
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- Authors
- Trabert, B., Peters, U., De Roos, A. J., Scholes, D., & Holt, V. L.
- Affiliations
- University of Washington (US)
- Group Health Cooperative (US)
- Corresponding author
- Trabert, Britton
- Venue
- British Journal of Nutrition
- Publisher
- Cambridge University Press (CUP)
- Published
- 2010-09-28
- Volume
- 105
- Issue
- 3
- Pages
- 459-467
- ISSN
- 0007-1145 (ISSN-L)
- 1475-2662
- PMC
- PMC3374872
- OpenAlex
- W2166752999
- Cited by
- 125
- References
- 29
- Citations by year
- 2026: 8 · 2025: 18 · 2024: 13 · 2023: 11 · 2022: 11 · 2021: 11 · 2020: 9 · 2019: 3 · 2018: 8 · 2017: 4 · 2016: 3 · 2015: 5 · 2014: 5 · 2013: 9 · 2012: 5
- FWCI
- 6.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- British Journal Of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01 HD33792, R01HD033792, T32HD052462)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Oncology › Cancer Risks and Factors
- Keywords
- endometriosis, diet, dietary risk factors, total fat intake, beta-carotene, fruit consumption, dairy products, steroid hormones
- MeSH terms
- Adolescent, Adult, Dairy Products, Diet, Dietary Fats, Endometriosis, Female, Fruit, Humans, Middle Aged, Surveys and Questionnaires, Risk Factors, United States, Odds Ratio, Case-Control Studies, beta Carotene, Young Adult
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