The DOI matches its Crossref record; 51 of the 52 references it cites were found in a registry or an index.
Obesity, inflammation and the immune system
Open accessAbstract
Obesity shares with most chronic diseases the presence of an inflammatory component, which accounts for the development of metabolic disease and other associated health alterations. This inflammatory state is reflected in increased circulating levels of pro-inflammatory proteins, and it occurs not only in adults but also in adolescents and children. The chronic inflammatory response has its origin in the links existing between the adipose tissue and the immune system. Obesity, like other states of malnutrition, is known to impair the immune function, altering leucocyte counts as well as cell-mediated immune responses. In addition, evidence has arisen that an altered immune function contributes to the pathogenesis of obesity. This review attempts to briefly comment on the various plausible explanations that have been proposed for the phenomenon: (1) the obesity-associated increase in the production of leptin (pro-inflammatory) and the reduction in adiponectin (anti-inflammatory) seem to affect the activation of immune cells; (2) NEFA can induce inflammation through various mechanisms (such as modulation of adipokine production or activation of Toll-like receptors); (3) nutrient excess and adipocyte expansion trigger endoplasmic reticulum stress; and (4) hypoxia occurring in hypertrophied adipose tissue stimulates the expression of inflammatory genes and activates immune cells. Interestingly, data suggest a greater impact of visceral adipose tissue and central obesity, rather than total body fat, on the inflammatory process. In summary, there is a positive feedback loop between local inflammation in adipose tissue and altered immune response in obesity, both contributing to the development of related metabolic complications.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Long‐time stress appears to also contribute to pathogenesis of other sepsis comorbidities including obesity, diabetes, asthma and immunosenescence (de Heredia et al., 2012; Epel et al., 2004; Epel et al., 2008; Rod et al., 2012; Thakur et al., 2017).”
From On race, human variation, and who gets and dies of sepsis (2022) · cites this paper as de Heredia et al., 2012
Experimental — accuracy not yet measuredIn the citing paper
“CMV reactivation might be even more frequent in obesity, because excess adiposity drives chronic systemic inflammation and oxidative stress (Aroor and DeMarco 2014; Cervellati et al. 2014; de Heredia et al. 2012; Kanneganti and Dixit 2012; Le Lay and Simard 2014), which in turn can reactivate CMV directly (Cinatl et al. 1999; Docke et al. 1994; Jaganjac et al. 2010; Prosch et al. 1995; Speir 2000;”
From Is immunosenescence influenced by our lifetime “dose” of exercise? (2016) · cites this paper as de Heredia et al. 2012
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Obesity is associated with macrophage accumulation in adipose tissue
Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041
Inflammation and metabolic disorders
Hotamisligil, G. S. (2006) · Nature · doi:10.1038/nature05485 · Cited by 9,199
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Lumeng, C. N., Bodzin, J. L., & Saltiel, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29881 · Cited by 4,664
Obesity and the Metabolic Syndrome in Children and Adolescents
Weiss, R., Dziura, J., Burgert, T. S., Tamborlane, W. V., Taksali, S. E., Yeckel, C. W., Allen, K., Lopes, M., Savoye, M., Morrison, J. A., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa031049 · Cited by 3,495
Adipocytokines: mediators linking adipose tissue, inflammation and immunity
Tilg, H., & Moschen, A. R. (2006) · Nature reviews. Immunology · doi:10.1038/nri1937 · Cited by 3,272
Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome
Wajchenberg, B. L. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.6.0415 · Cited by 2,961
Adipokines: inflammation and the pleiotropic role of white adipose tissue
Trayhurn, P., & Wood, I. S. (2004) · British Journal of Nutrition · doi:10.1079/bjn20041213 · Cited by 2,210
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
Odegaard, J. I., Ricardo-Gonzalez, R. R., Goforth, M. H., Morel, C. R., Subramanian, V., Mukundan, L., Eagle, A. R., Vats, D., Brombacher, F., Ferrante, A. W., et al. (2007) · Nature · doi:10.1038/nature05894 · Cited by 2,107
Recent advances in the relationship between obesity, inflammation, and insulin resistance.
Bastard, J., Maachi, M., Lagathu, C., Kim, M. J., Caron, M., Vidal, H., Capeau, J., & Fève, B. (2006) · PubMed · Cited by 2,090
Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome — An allostatic perspective
Virtue, S., & Vidal-Puig, A. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2009.12.006 · Cited by 1,013
Research works printed but not linked: 2
- Gorman, 2004, Health: the fires within, Time, 163, 38
- Pérez de Heredia, 2010, Lactate enhances the inflammatory response in human preadipocytes in vitro, Obes Rev, 11, 122
Cited by
Sorted by citations
Items 401–500 of 846
From pathophysiology to novel approaches for obesity-associated hypertension
Kanbay, M., Yayci, E., Genc, C., Çöpür, S., Aktaş, Ö. Y., Sarafidis, P. A., Covic, A. C., Ortíz, A., & Laffin, L. J. (2025) · Clinical Kidney Journal · doi:10.1093/ckj/sfaf218 · Cited by 10
Mechanism-Based Biomarker Prediction for Low-Grade Inflammation in Liver and Adipose Tissue
van Bilsen, J. H. M., van den Brink, W., van den Hoek, A. M., Dulos, R., Caspers, M. P. M., Kleemann, R., Wopereis, S., & Verschuren, L. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.703370 · Cited by 10
Hubert, A., Achour, D., Grare, C., Zarcone, G., Muntaner, M., Hamroun, A., Gauthier, V., Amouyel, P., Matran, R., Zerimech, F., et al. (2023) · Environment International · doi:10.1016/j.envint.2023.107913 · Cited by 10
Multivariate resting-state functional connectomes predict and characterize obesity phenotypes
Wang, J., Dong, D., Liu, Y., Yang, Y., Chen, X., He, Q., Lei, X., Feng, T., Qiu, J., & Chen, H. (2023) · Cerebral Cortex · doi:10.1093/cercor/bhad122 · Cited by 10
Irisin as a Novel Biomarker of Subclinical Atherosclerosis in Severe Obesity
Carmona‐Maurici, J., Rosa, A., Azcona-Granada, N., Peña, E., Ricart-Jané, D., Viñas, A., López-Tejero, M. D., Domingo, J. C., Miñarro, A., Baena‐Fustegueras, J. A., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24098171 · Cited by 11
COVID-19, Anxiety, and Body Mass Index Increase Leptin Levels: a Cross-sectional Multicentric Study
Réus, G. Z., Recco, K. C. C., Machado, K. M. S. H., da Silva, R. H., Arent, C. O., Amboni, G., Niero, F. S., Pedro, L. C., Borba, L. A., Bagatini, M. D., et al. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03788-9 · Cited by 10
Jungert, A., & Neuhäuser‐Berthold, M. (2019) · The Journals of Gerontology Series A · doi:10.1093/gerona/glz010 · Cited by 10
Salinas, C., Espinosa, G., Morales, N., Henríquez, C., Morán, G., Gajardo, G., & Uberti, B. (2020) · Research in Veterinary Science · doi:10.1016/j.rvsc.2020.06.013 · Cited by 10
Mitigating the Effects of Oxidative Sperm DNA Damage
Pini, T., Makloski, R., Maruniak, K., Schoolcraft, W. B., & Katz‐Jaffe, M. G. (2020) · Antioxidants · doi:10.3390/antiox9070589 · Cited by 10
Physical activity may mitigate COVID‐19 infections in people with obesity: A call to action
Economos, C. D., Dietz, W. H., Tullie, K., & Sallis, J. F. (2021) · Obesity · doi:10.1002/oby.23269 · Cited by 10
Effect of abdominal fat distribution on severity of acute pancreatitis
Beydogan, E., Gülle, S., Gezer, C., & Böyük, B. (2021) · Clinical and Experimental Hepatology · doi:10.5114/ceh.2021.109345 · Cited by 10
Cheng, Y., Liu, L., Mo, S., Gao, J., Zhang, H., Zhang, H., Zhang, C., Song, X., Li, L., & Geng, Z. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/3027708 · Cited by 10
Attractive and healthy-looking male faces do not show higher immunoreactivity
Pátková, Ž., Schwambergová, D., Fialová, J., Třebický, V., Stella, D., Kleisner, K., & Havlı́ček, J. (2022) · Scientific Reports · doi:10.1038/s41598-022-22866-x · Cited by 10
Cha, K. S., Park, C. Y., Lee, S. E., Kim, T. Y., & Han, S. N. (2020) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2020.108464 · Cited by 9
Park, T. H., Lin, J.-H., Chung, C., Zheng, Z. S., & Li, C. (2023) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2023.05.022 · Cited by 9
González-Palomo, A. K., García, J. D. C., Saldaña-Villanueva, K., Martínez, F. D. B., Méndez‐Rodríguez, K. B., Quintana, L. E. A., Álvarez, J. C. M., & Vázquez, F. J. P. (2025) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-024-02116-5 · Cited by 9
Elizagaray, S. I. R., & Soria, E. A. (2014) · Recent Patents on Inflammation & Allergy Drug Discovery · doi:10.2174/1872213x08666140619104944 · Cited by 8
Abdel-Hamid, H. M., Rizk, H., & Magdy, S. (2021) · Indian Journal of Tuberculosis · doi:10.1016/j.ijtb.2021.01.006 · Cited by 9
On race, human variation, and who gets and dies of sepsis
Brinkworth, J. F., & Shaw, J. G. (2022) · American Journal of Biological Anthropology · doi:10.1002/ajpa.24527 · Cited by 9
Effect of fasting on short‐term visual plasticity in adult humans
Animali, S., Steinwurzel, C., Dardano, A., Sancho‐Bornez, V., Prato, S. D., Morrone, M. C., Daniele, G., & Binda, P. (2022) · European Journal of Neuroscience · doi:10.1111/ejn.15873 · Cited by 9
MacDonald, C., Madkia, A.-L., Mounier‐Véhier, C., Severi, G., & Boutron‐Ruault, M. (2022) · European Journal of Nutrition · doi:10.1007/s00394-022-03053-0 · Cited by 9
Navarro‐Lomas, G., Plaza‐Florido, A., De‐la‐O, A., Castillo, M. J., & Amaro‐Gahete, F. J. (2023) · American Journal of Human Biology · doi:10.1002/ajhb.23945 · Cited by 9
Pérez-López, F. R., López-Baena, M. T., Ulloque‐Badaracco, J. R., & Benites-Zapata, V. A. (2023) · Reproductive Sciences · doi:10.1007/s43032-023-01306-9 · Cited by 9
Calorie Restriction Impairs Anti-Tumor Immune Responses in an Immunogenic Preclinical Cancer Model
Nguyen, D. T., Susukida, T., Ucche, S., He, K., Sasaki, S., Hayashi, R., & Hayakawa, Y. (2023) · Nutrients · doi:10.3390/nu15163638 · Cited by 9
Dragoumani, K., Troumbis, A. Y., Bacopoulou, F., & Chrousos, G. P. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13091322 · Cited by 11
Kaur, Y., Wang, D. X., Liu, H., & Meyre, D. (2018) · Obesity Reviews · doi:10.1111/obr.12806 · Cited by 10
Nutrigenetics of antioxidant enzymes and micronutrient needs in the context of viral infections
Birk, R. Z. (2020) · Nutrition Research Reviews · doi:10.1017/s0954422420000244 · Cited by 10
Prospective investigation of polyomavirus infection and the risk of adult glioma
Egan, K. M., Kim, Y., Bender, N., Hodge, J. M., Coghill, A. E., Smith‐Warner, S. A., Rollison, D. E. M., Teras, L. R., Grimsrud, T. K., & Waterboer, T. (2021) · Scientific Reports · doi:10.1038/s41598-021-89133-3 · Cited by 9
Bykerk, V. P., Blauvelt, A., Curtis, J. R., Gaujoux-Viala, C., Kvien, T. K., Winthrop, K. L., Tilt, N., Popova, C., Xavier Mariette, A., & Haraoui, B. P. (2021) · ACR Open Rheumatology · doi:10.1002/acr2.11259 · Cited by 9
Body Mass Index and Risk for COVID-19-Related Hospitalization in Adults Aged 50 and Older in Europe
Ohno, M., & Dzúrová, D. (2022) · Nutrients · doi:10.3390/nu14194001 · Cited by 9
Mânica-Cattani, M. F., Cadoná, F. C., de Oliveira, R., da Silva, T., Machado, A. K., Barbisan, F., Duarte, M. M. M. F., & da Cruz, I. B. M. (2012) · Open Journal of Genetics · doi:10.4236/ojgen.2012.24026 · Cited by 9
Rock, K., Hayward, R. D., & Edhayan, E. (2019) · Clinical Obesity · doi:10.1111/cob.12293 · Cited by 9
Leptin: a pleitropic factor in physiology
Almabhouh, F. A., Isyraqiah, F., Ibrahim, H., & Singh, H. (2019) · Journal of Clinical and Health Sciences · doi:10.24191/jchs.v4i2.7551 · Cited by 10
Obesity and HLA in multiple sclerosis
Marrie, R. A., & Beck, C. A. (2014) · Neurology · doi:10.1212/wnl.0000000000000195 · Cited by 9
Huang, J.-W., He, W., Zhang, Y.-T., Yang, M., Jin, N.-X., Leskinen, A., Komppula, M., Roponen, M., Lin, L., Gui, Z., et al. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.178112 · Cited by 8
Liu, Z., Li, Q., Zhao, F. Q., & Chen, J. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156602 · Cited by 8
Lv, M.-Y., Zheng, Y., Yuan, M., Zhang, E., Zheng, M., Liu, G., Gu, W., & Xu, H.-X. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1546119 · Cited by 8
Yu, L., Yuan, J. T., Meng, M., Pan, H., Ge, L., Wang, L., & Li, X. (2025) · Metabolism · doi:10.1016/j.metabol.2025.156461 · Cited by 8
Bae, N.-Y., Kim, M.-J., Kim, K.-B.-W.-R., Ahn, N.-K., Choi, Y.-U., Park, J., Park, S.-H., & Ahn, D.-H. (2015) · Journal of the Korean Society of Food Science and Nutrition · doi:10.3746/jkfn.2015.44.8.1128 · Cited by 8
Pantoja‐Arévalo, L., Gesteiro, E., Matthias, T., Urrialde, R., & González‐Gross, M. (2023) · Biomedicines · doi:10.3390/biomedicines11123335 · Cited by 8
Unveiling the impact of TREM-2+ Macrophages in metabolic disorders
Contreras, M., Matos, A. D. O., Dantas, P. H. D. S., Neto, J. R. D. C., Silva‐Sales, M., & Sales‐Campos, H. (2024) · Cellular Immunology · doi:10.1016/j.cellimm.2024.104882 · Cited by 10
Yamawaki, Y., Oue, K., Shirawachi, S., Asano, S., Harada, K., & Kanematsu, T. (2016) · Japanese Dental Science Review · doi:10.1016/j.jdsr.2016.06.001 · Cited by 8
Elffers, T. W., de Mutsert, R., Lamb, H. J., Maan, A. C., Macfarlane, P. W., van Dijk, K. W., Rosendaal, F. R., Jukema, J. W., & Trompet, S. (2017) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2017.11.030 · Cited by 8
Yang, E., Lee, C., Che, D. N., Jang, S. I., & Kim, Y. (2019) · Journal of Food Biochemistry · doi:10.1111/jfbc.12806 · Cited by 8
Influence of obesity on the risk of recurrent acute diverticulitis
Turner, G. A., O’Grady, M. J., Frizelle, F., Eglinton, T., & Sharma, P. V. (2020) · ANZ Journal of Surgery · doi:10.1111/ans.15784 · Cited by 8
Bhutani, S., & McClain, A. C. (2022) · Nutrients · doi:10.3390/nu14153178 · Cited by 7
Rate of Nutrition-Related Chronic Diseases Among a Multi-Ethnic Group of Uninsured Adults
Ajabshir, S., Stumbar, S. E., Lachica, I., Gates, K., Qureshi, Z. I., & Huffman, F. G. (2022) · Cureus · doi:10.7759/cureus.28802 · Cited by 10
COVID-19 Spotlights Connections between Disease and Multiple Lifestyle Factors
Enichen, E. J., Harvey, C., & Demmig‐Adams, B. (2022) · American Journal of Lifestyle Medicine · doi:10.1177/15598276221123005 · Cited by 10
Walther, A., Penz, M. S., Ijacic, D., & Rice, T. (2017) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2017.00207 · Cited by 8
Manning, K. F., Bakhshaie, J., Shepherd, J. M., Jones, J. G., Timpano, K. R., Viana, A. G., & Zvolensky, M. J. (2019) · Fatigue Biomedicine Health & Behavior · doi:10.1080/21641846.2019.1661942 · Cited by 8
Murugan, R., Haridevamuthu, B., Gopinath, P., Rajagopal, R., Arokiyaraj, S., & Arockiaraj, J. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.176214 · Cited by 7
Additive effects of depression and obesity on neural correlates of inhibitory control
Kaufmann, L., Custers, E., Vreeken, D., Snabel, J. M., Morrison, M. C., Kleemann, R., Wiesmann, M., Hazebroek, E. J., Aarts, E., & Kiliaan, A. J. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.06.093 · Cited by 7
He, L. R., Zhang, L., Fu, S., Wei, S., & Liu, Y. (2024) · Obesity Surgery · doi:10.1007/s11695-024-07415-x · Cited by 9
Immunometabolic Changes Following Gastric Bypass and Sleeve Gastrectomy: A Comparative Study
Rivera-Carranza, T., Azaola‐Espinosa, A., Bojalil‐Parra, R., Zúñiga-León, E., Girón, A. L.-T., Rojano‐Rodriguez, M., & Nájera-Medina, O. (2025) · Obesity Surgery · doi:10.1007/s11695-024-07598-3 · Cited by 7
Cellular Immunity in Obesity: Pathophysiological Insights and the Impact of Bariatric Surgery
Rivera-Carranza, T., Girón, A. L.-T., Gónzalez-Vázquez, R., Vázquez-Cárdenas, P., Esquivel-Campos, A. L., Mendoza‐Pérez, F., Rojano‐Rodriguez, M., Mimiaga-Hernández, C., Cifuentes-Goches, J. C., Valle, O. E. P., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26209867 · Cited by 7
Mechanism-Based Therapeutic Approaches to Cachexia
Penna, F., Bonelli, G., Baccino, F. M., & Costelli, P. (2013) · Vitamins and hormones · doi:10.1016/b978-0-12-410473-0.00011-8 · Cited by 7
Inflammatory mediators in the adipo-renal axis: leptin, adiponectin, and soluble ICAM-1
Hua, Y., Herder, C., Kalhoff, H., Buyken, A. E., Esche, J., Krupp, D., Wudy, S. A., & Remer, T. (2020) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00257.2020 · Cited by 7
The Role of Glucose–Lymphocyte Ratio in Evaluating the Severity of Coronary Artery Disease
Serhatlıoğlu, F., Çetınkaya, Z., & Yılmaz, Y. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13226711 · Cited by 7
Jungert, A., & Neuhäuser‐Berthold, M. (2018) · Experimental Gerontology · doi:10.1016/j.exger.2018.06.024 · Cited by 7
Rachmah, Q., Nindya, T. S., Aji, A. S., Pattimah, S., Rachmah, N., Maulana, N. I., Agustin, A. M., & Astina, J. (2021) · Media Gizi Indonesia · doi:10.20473/mgi.v16i3.273-279 · Cited by 7
Greasing the inflammatory pathogenesis of viral pneumonias in diabetes
Damen, M. S. M. A., Alarcon, P. C., SHAH, A. S., & Divanovic, S. (2022) · Obesity Reviews · doi:10.1111/obr.13415 · Cited by 10
Association between body fat distribution and B-lymphocyte subsets in peripheral blood
Prechtl, P., Schmitz, T., Pochert, N., Traidl‐Hoffmann, C., Linseisen, J., Meisinger, C., & Freuer, D. (2023) · Immunity & Ageing · doi:10.1186/s12979-023-00372-6 · Cited by 7
Body Mass Index Predicts Failure of Surgical Management in Benign Prostatic Hyperplasia
Willder, J. M., Walker, V. C., Halbert, G. L., Dick, C., Orange, C., Qayyum, T., Horgan, P. G., Underwood, M. A., & Edwards, J. (2012) · Urologia Internationalis · doi:10.1159/000345440 · Cited by 7
Woods, J., Iuliano-Burns, S., & Walker, K. Z. (2013) · Immunity & Ageing · doi:10.1186/1742-4933-10-32 · Cited by 7
Naderi, M., Hashemi, M. M., Dejkam, N., Bahari, G., Rezaei, M., & Taheri, M. (2017) · Acta Microbiologica et Immunologica Hungarica · doi:10.1556/030.64.2017.010 · Cited by 7
Progranulin concentration in relation to bone mineral density among obese individuals
Milajerdi, A., Maghbooli, Z., Mohammadi, F., Hosseini, B., & Mirzaei, K. (2018) · Archives of Endocrinology and Metabolism · doi:10.20945/2359-3997000000022 · Cited by 7
Chemerin predicts carotid intima‐media thickening in severe obesity
Ministrini, S., Ricci, M. A., Migliola, E. N., VUONO, S. D., D’Abbondanza, M., Paganelli, M. T., Vaudo, G., Siepi, D., & Lupattelli, G. (2020) · European Journal of Clinical Investigation · doi:10.1111/eci.13256 · Cited by 7
Hunsche, C., de Toda, I. M., Hernández, O., Jiménez, B., Díaz, L. E., Marcos, A., & la Fuente, M. D. (2020) · Free Radical Research · doi:10.1080/10715762.2020.1800004 · Cited by 7
Self-citationObesity, Inflammation and Neurological Alterations
Spinas, E., Saggini, A., Kritas, S. K., Cerulli, G. G., Caraffa, A., Antinolfi, P., Pantalone, A., Frydas, A., Tei, M. M., Speziali, A., et al. (2014) · European Journal of Inflammation · doi:10.1177/1721727x1401200302 · Cited by 7
Keshavarz, E., Ahangaran, A., Khalili, P. E., Maheronnaghsh, R., Chavoshi, M., & Rouzrokh, P. (2020) · MAEDICA – a Journal of Clinical Medicine · doi:10.26574/maedica.2020.15.1.99 · Cited by 7
Se-Jun, P. A. R. K., Kim, Y. N., Oh, B. K., & Kang, J. (2024) · Scientific Reports · doi:10.1038/s41598-024-82513-5 · Cited by 7
Psoriatic arthritis flare incidence, definition and risk factors: a systematic review
Hojeij, B., Koc, G. H., Luime, J. J., Vis, M., Coates, L. C., Kok, M. R., & Tchetverikov, I. (2025) · Lara D. Veeken · doi:10.1093/rheumatology/keaf247 · Cited by 6
Feinkohl, I., Hadzidiakos, D. A., Dschietzig, T. B., Janke, J., Heinrich, M., Slooter, A. J. C., Spies, C., Winterer, G., & Pischon, T. (2025) · Scientific Reports · doi:10.1038/s41598-025-31986-z · Cited by 6
Kim, S. J., Cho, D. H., Lee, G. Y., An, J. H., & Han, S. N. (2021) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2021.108880 · Cited by 6
Schmitz, T., Freuer, D., Meisinger, C., & Linseisen, J. (2023) · Inflammation Research · doi:10.1007/s00011-023-01777-1 · Cited by 6
Brown, G., Marchwicka, A., & Marcinkowska, E. (2024) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2023.12.001 · Cited by 7
King, S., Osei, F., & Marsh, C. A. (2024) · Reproductive Medicine · doi:10.3390/reprodmed5020010 · Cited by 6
Xiao, Z., He, Z., Nguyen, H. L. L., Thakur, R., Hammami, M. B., Narvel, H., Vegivinti, C. T. R., Townsend, N., Billett, H. H., & Murakhovskaya, I. (2024) · Annals of Hematology · doi:10.1007/s00277-024-05836-3 · Cited by 6
Skapino, E., Gonzalez-Gayan, L., Seral-Cortés, M., Sabroso‐Lasa, S., Llorente-Cereza, M. T., Leis, R., Aguilera, C. M., Gil‐Campos, M., Moreno, L. A., & Bueno, G. (2024) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2024.103811 · Cited by 7
Impact of Metabolic States on SARS-CoV-2 Vaccine Responses in Mouse Models of Obesity and Diabetes
Smith, O. A., Fujimoto, B., Wong, T. A. S., To, A., Odo, T., Ball, A. H., Haun, B. K., Muramatsu, H., Tam, Y. K., Pardi, N., et al. (2024) · COVID · doi:10.3390/covid5010002 · Cited by 7
Tunçay, A., Yılmaz, Y., Baran, O., & Keleşoğlu, Ş. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14082634 · Cited by 6
Aging effect on plasma metabolites and hormones concentrations in riding horses
Kawasumi, K., Yamamoto, M., Koide, M., Okada, Y., Mori, N., YAMAMOTO, I., & Arai, T. (2015) · Open Veterinary Journal · doi:10.5455/ovj.2015.v5.i2.p154 · Cited by 6
Grèze, C., Pereira, B., Boirie, Y., Guy, L., Garrouste, C., & Heng, A.-É. (2018) · Néphrologie & Thérapeutique · doi:10.1016/j.nephro.2018.01.002 · Cited by 6
Prevalence of Helicobacter pylori Infection in Bariatric Surgery Patients
Baillargeon, D., Greenblatt, M., Côté, M., Nadeau, M., Couture, C.-Y., Hould, F., Bouvet-Bouchard, L., Tchernof, A., & Biertho, L. D. (2023) · Obesity Surgery · doi:10.1007/s11695-023-06638-8 · Cited by 6
Abbadi, A., Gentili, S., Tsoumani, E., Brandtmuller, A., Hendel, M. K., Salomonsson, S., Calderón‐Larrañaga, A., & Vetrano, D. L. (2024) · Aging Clinical and Experimental Research · doi:10.1007/s40520-024-02808-5 · Cited by 6
Zhang, W., Chen, H., Sun, C., Wu, B., Bai, B., Liu, H., Shan, X., Liang, G., & Zhang, Y. (2019) · Molecular Medicine Reports · doi:10.3892/mmr.2019.10157 · Cited by 6
Obesity considerations during the COVID-19 outbreak
Dohet, F., Loap, S., Menzel, A., Iddir, M., Dadoun, F., Bohn, T., & Samouda, H. (2021) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831/a000695 · Cited by 6
Body mass index and vaccine responses following influenza vaccination during pregnancy
Clarke, M. F., Goodchild, L., Evans, S., Giles, L. C., Sullivan, S. G., Barr, I., Lambert, S. B., & Marshall, H. S. (2021) · Vaccine · doi:10.1016/j.vaccine.2021.06.065 · Cited by 6
Gutierrez, S. D., Da, S., Barbosa, L. P., dos Santos, P. W. D. S., Maciel, L. A., Leite, P. L. D. A., Rosa, T. D. S., Deus, L. A., Lewis, J. E., & Simões, H. G. (2021) · Journal of Clinical and Translational Research · doi:10.18053/jctres.07.202104.008 · Cited by 5
Bacillus Calmette-Guérin vaccination at birth: Effects on infant growth. A randomized clinical trial
Kjærgaard, J., Stensballe, L. G., Birk, N. M., Nissen, T. N., Thøstesen, L. M., Pihl, G. T., Nielsen, A. V., Kofoed, P., Aaby, P., Pryds, O. A., et al. (2016) · Early Human Development · doi:10.1016/j.earlhumdev.2016.05.015 · Cited by 6
Fried, E. I., & Haslbeck, J. M. B. (2019) · doi:10.31234/osf.io/5mvz4 · Cited by 6
Yang, Z., Luo, Y., He, J., Yuan, Y., Liu, Q., Guo, J., Lin, Y., Sun, L., & Fan, G. (2025) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2025.112070 · Cited by 6
Liu, C., Liao, Y., Jiang, H., Tang, Q., He, C., Wang, Y., Ren, M., Wang, C., Chen, S., Tan, L., et al. (2025) · Food Research International · doi:10.1016/j.foodres.2025.116185 · Cited by 5
Maternal adiposity moderates associations between dietary, serum, and human milk n-3 and n-6 PUFA
Zielinska-Pukos, M. A., Bryś, J., & Hamułka, J. (2025) · Scientific Reports · doi:10.1038/s41598-025-00940-4 · Cited by 5
The Glymphatic System and Obesity: A Diffusion Tensor Imaging ALPS Study
Park, K. M., Wi, J.-H., Park, B. S., Lee, D. A., & Kim, J. (2025) · Biomedicines · doi:10.3390/biomedicines13112585 · Cited by 6
Huynh, C. G., Huynh, N. X., Truong, H. B. T., Thai, T. T., & Doan, T. P. T. (2023) · Medicine · doi:10.1097/md.0000000000034222 · Cited by 5
Aging alone or combined with obesity increases white adipose tissue inflammatory status in male mice
Bournot, L., Payet, T., Sicard, F., Breniere, T., Astier, J., Roux, J., Bariohay, B., & Landrier, J. (2024) · Scientific Reports · doi:10.1038/s41598-024-67179-3 · Cited by 5
Pinho, A. C. O., Barbosa, P., Lázaro, A., Tralhão, J. G., Pereira, M. J., Paiva, A. A., Laranjeira, P., & Carvalho, E. (2024) · Immunology Letters · doi:10.1016/j.imlet.2024.106911 · Cited by 5
The evolution of immune profiling: will there be a role for nanoparticles?
Eremina, O. E., Vazquez, C., Larson, K. N., Mouchawar, A. C., Fernando, A., & Zavaleta, C. L. (2024) · Nanoscale Horizons · doi:10.1039/d4nh00279b · Cited by 5
Wang, C., Reimann, B., Nawrot, T. S., Martens, D. S., Wright, J., McEachan, R., Lepeule, J., Yuan, W. L., Chatzi, L., Vafeiadi, M., et al. (2025) · Environment International · doi:10.1016/j.envint.2025.109630 · Cited by 7
Metadata
- Authors
- de Heredia, F. P., Gómez-Martínez, S., & Marcos, A.
- Affiliations
- Consejo Superior de Investigaciones Científicas (ES)
- Venue
- Proceedings of the Nutrition Society
- Publisher
- Cambridge University Press (CUP)
- Published
- 2012-03-20
- Volume
- 71
- Issue
- 2
- Pages
- 332-338
- ISSN
- 0029-6651 (ISSN-L)
- 1475-2719
- OpenAlex
- W2001652786
- Cited by
- 845
- References
- 52
- Citations by year
- 2026: 32 · 2025: 97 · 2024: 87 · 2023: 94 · 2022: 92 · 2021: 86 · 2020: 65 · 2019: 47 · 2018: 44 · 2017: 35 · 2016: 39 · 2015: 37 · 2014: 39 · 2013: 40 · 2012: 10
- FWCI
- 5.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of The Nutrition Society (publishedVersion)
- PubMed (publishedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Keywords
- obesity, chronic inflammation, leptin, adiponectin, free fatty acids, Toll-like receptors, adipokines, endoplasmic reticulum stress, hypoxia, visceral adipose tissue, abdominal obesity, immune function, metabolic disorders, children and adolescents
- MeSH terms
- Adipose Tissue, Hypoxia, Endoplasmic Reticulum, Fatty Acids, Humans, Immune System, Inflammation, Obesity, Overnutrition, Adipokines, Endoplasmic Reticulum Stress
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
