Efficacy of meaning-centered group psychotherapy for cancer survivors: a randomized controlled trial
Open accessAbstract
BACKGROUND: The aim of this study was to assess the efficacy of meaning-centered group psychotherapy for cancer survivors (MCGP-CS) to improve personal meaning, compared with supportive group psychotherapy (SGP) and care as usual (CAU). METHOD: A total of 170 cancer survivors were randomly assigned to one of the three study arms: MCGP-CS (n = 57); SGP (n = 56); CAU (n = 57). The primary outcome measure was the Personal Meaning Profile (PMP; total score). Secondary outcome measures were subscales of the PMP, psychological well-being (Scales of Psychological Well-being; SPWB), post-traumatic growth (Posttraumatic Growth Inventory), Mental Adjustment to Cancer (MAC), optimism (Life Orientation Test-Revised), hopelessness (Beck's Hopelessness Scale), psychological distress (anxiety and depression, Hospital Anxiety and Depression Scale; HADS) and quality of life (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire; EORTC QLQ-C30). Outcome measures were assessed before randomization, post-intervention, and after 3 and 6 months of follow-up (FU). RESULTS: Linear mixed model analyses (intention-to-treat) showed significant differences between MCGP-CS, SGP and CAU on the total PMP score, and on (sub)scales of the PMP, SPWB, MAC and HADS. Post-hoc analyses showed significantly stronger treatment effects of MCGP-CS compared with CAU on personal meaning (d = 0.81), goal-orientedness (d = 1.07), positive relations (d = 0.59), purpose in life (d = 0.69); fighting spirit (d = 0.61) (post-intervention) and helpless/hopeless (d = -0.87) (3 months FU); and distress (d = -0.6) and depression (d = -0.38) (6 months FU). Significantly stronger effects of MCGP-CS compared with SGP were found on personal growth (d = 0.57) (3 months FU) and environmental mastery (d = 0.66) (6 months FU). CONCLUSIONS: MCGP-CS is an effective intervention for cancer survivors to improve personal meaning, psychological well-being and mental adjustment to cancer in the short term, and to reduce psychological distress in the long run.
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MCP was more effective in improving goal-orientedness and fighting spirit compared to the Supportive Group, as well as personal growth and environmental mastery at the 6-month follow-up.
“MCP was more effective in improving goal-orientedness and a fighting spirit compared to the Supportive Group, as well as personal growth and environmental mastery at the 6-month follow-up.”
From Spanish Adaptation of Meaning-Centered Psychotherapy for Participants With Cancer: Study Protocol of a Randomized Control Trial (2022) · cites this paper as [9]
The Results (Efficacy of MCGP-CS; page not provided) report stronger effects than the Supportive Group on personal growth at three months and environmental mastery at six months. Stronger effects on goal-orientedness and fighting spirit were reported relative to care as usual, not the Supportive Group. The claim therefore misstates both the comparator for two outcomes and the follow-up time for personal growth. (LLM, conf=0.93)
Experimental — accuracy not yet measuredAccounting for an expected 30% dropout rate, the study requires a total sample size of 118 participants (59 per condition).
“Finally, we have considered possible sample loss during the treatment program, and based on studies of interventions with MCP, we expect a 30% dropout rate (9). Therefore, taking this outcome into account, our study requires a total sample size of 118 participants (59 participants per experimental condition).”
From Spanish Adaptation of Meaning-Centered Psychotherapy for Participants With Cancer: Study Protocol of a Randomized Control Trial (2022) · cites this paper as [9]
The Methods > Sample size passage says the cited study anticipated 30% loss at follow-up, supporting the citing authors’ use of a 30% loss estimate. It does not describe 30% dropout during the treatment program; the 118-participant target is the citing authors’ own calculation, not a figure attributed to this source. (LLM, conf=0.88)
Experimental — accuracy not yet measuredIn an RCT with cancer survivors and 6-month follow-up, MCP improved personal meaning, positive relations, purpose in life, fighting spirit, hopelessness, goal-orientedness, psychological wellbeing and adjustment, and reduced psychological distress and depressive symptoms more than TAU.
“The results at the 6-month follow-up showed that the MCP treatment improved personal meaning, positive relations, purpose in life, a fighting spirit, hopelessness, goal-orientedness, and psychological wellbeing and adjustment, and it reduced psychological distress and depressive symptoms more than the TAU condition.”
From Spanish Adaptation of Meaning-Centered Psychotherapy for Participants With Cancer: Study Protocol of a Randomized Control Trial (2022) · cites this paper as [9]
The Results (Efficacy of MCGP-CS) report stronger effects than care as usual on the listed outcomes, but not all at the six-month follow-up: personal meaning, goal-orientedness, positive relations, purpose in life, and fighting spirit were reported post-intervention; helpless/hopeless at three months; and distress and depression at six months. The Results also report no significant group difference on the separate Beck’s Hopelessness Scale, so the claim’s unqualified reference to improved hopelessness is misleading. (LLM, conf=0.91)
Experimental — accuracy not yet measuredTreatment efficacy studies have found a dropout rate of 30%.
“Treatment efficacy studies have found a dropout rate of 30% (9), which can interfere with the development of the study as well as the type of statistical analysis that we can perform.”
From Spanish Adaptation of Meaning-Centered Psychotherapy for Participants With Cancer: Study Protocol of a Randomized Control Trial (2022) · cites this paper as [9]
The Methods (Sample size; page unavailable) anticipate a 30% loss to follow-up for planning purposes; they do not report a 30% dropout rate found by treatment efficacy studies. The Results (Study population; page unavailable) report that 74% completed the six-month follow-up, implying 26% did not. (LLM, conf=0.88)
Experimental — accuracy not yet measuredPrevious studies suggest that intervening in meaning in life in cancer patients can be an effective treatment to improve negative emotional states and lead to better coping with life after a cancer diagnosis.
“Therefore, previous studies suggest that intervening in meaning in life in cancer patients can be an effective treatment to improve the aforementioned negative emotional states and lead to better coping with life after a cancer diagnosis (8, 9).”
From Spanish Adaptation of Meaning-Centered Psychotherapy for Participants With Cancer: Study Protocol of a Randomized Control Trial (2022) · cites this paper as [9]
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BackgroundThe Meaning Making Model Applied to Community-Dwelling Adults with Chronic Pain
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Sharpe, L., Richmond, B., Todd, J., Dudeney, J. E., Dear, B. F., Szabó, M., Sesel, A.-L., Forrester, M. A., & Menzies, R. E. (2023) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2023.111514 · Cited by 26 · see citing works
Posttraumatic growth after cancer
Chung, M. C. (2023) · Oxford University Press eBooks · doi:10.1093/oso/9780198727323.003.0005 · Cited by 24 · see citing works
Wang, Z., Xu, D., Yu, S., Liu, Y., Han, Y., Zhao, W., & Zhang, W. (2024) · Worldviews on Evidence-Based Nursing · doi:10.1111/wvn.12752 · Cited by 23 · see citing works
Palliative care during and following allogeneic hematopoietic stem cell transplantation
Mitchell, S. A. (2018) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0000000000000327 · Cited by 23 · see citing works
Holtmaat, K., van der Spek, N., Lissenberg-Witte, B. I., Cuijpers, P. J., & Leeuw, I. M. V. (2018) · Supportive Care in Cancer · doi:10.1007/s00520-018-4325-8 · Cited by 23 · see citing works
Chen, J., Liu, L., Wang, Y., Qin, H., & Liu, C. (2024) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2024.111609 · Cited by 23 · see citing works
Marco, J. H., Llombart, P., Retes, R. R., García-Conde, A., Corral, V., Guillén, V., & Perez, D. S. (2024) · Behavior Therapy · doi:10.1016/j.beth.2024.03.005 · Cited by 26 · see citing works
Kim, C., & Choi, H. (2020) · Perspectives In Psychiatric Care · doi:10.1111/ppc.12635 · Cited by 21 · see citing works
“32,33 Frankl stated that life is meaningful whether individual lives are pleasurable or miserable and even under the most difficult conditions.”
Group Therapy for Patients With Medical Illness
Leszcz, M. (2020) · American Journal of Psychotherapy · doi:10.1176/appi.psychotherapy.20200005 · Cited by 20 · see citing works
Global Research Mapping of Psycho-Oncology Between 1980 and 2021: A Bibliometric Analysis
Ahmad, T., Ornos, E. D. B., Ahmad, S., Al-Wassia, R. K., Mushtaque, I., Shah, S. M., Al‐Omari, B., Baig, M., & Tang, K. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.947669 · Cited by 20 · see citing works
“Some other interventions are meaning-centered psychotherapy, mindfulness stress reduction, and mindfulness (LeMay and Wilson, 2008; Piet et al., 2012; Breitbart et al., 2015; Rouleau et al., 2015; Carlson, 2016; Okuyama et al., 2017; van der Spek et al., 2017).”
BackgroundSun, M., Tian, X., Peng, Y., Wang, Z., Lu, Y., & Xiao, W. (2024) · Asia-Pacific Journal of Oncology Nursing · doi:10.1016/j.apjon.2024.100388 · Cited by 19 · see citing works
Davari, S., Boogar, I. R., Talepasand, S., & Evazi, M. R. (2022) · Journal of Religion and Health · doi:10.1007/s10943-022-01594-6 · Cited by 23 · see citing works
Yu, Y., Chotipanvithayakul, R., Wichaidit, W., & Cai, W. (2022) · Psychology Research and Behavior Management · doi:10.2147/prbm.s359073 · Cited by 21 · see citing works
“0 points was for post-traumatic growth mean score.(42) Based on a systematic review, −8.”
BackgroundLi, L., Wang, L., Duan, Y., Xiao, P., Zhou, Y., Luo, X., Liu, X., Xie, J., & Cheng, A. S. K. (2022) · Cancer Medicine · doi:10.1002/cam4.5030 · Cited by 18 · see citing works
Boylan, J. M., Cundiff, J. M., Jakubowski, K., Pardini, D. A., & Matthews, K. A. (2018) · Annals of Behavioral Medicine · doi:10.1093/abm/kay006 · Cited by 20 · see citing works
Wáng, Q., Zhou, M., Zhao, D., Lv, G., Zhang, Y., Xie, Z., & Li, P. (2022) · Cancer Nursing · doi:10.1097/ncc.0000000000001138 · Cited by 19 · see citing works
Wang, J., Chen, H., Yang, L., Yu, X., Zhang, D., Zhao, Q., & Xiao, M. (2023) · Journal of Multidisciplinary Healthcare · doi:10.2147/jmdh.s438342 · Cited by 18 · see citing works
Positive Psychology Approaches to Interventions for Cancer Dyads: A Scoping Review
Otto, A. K., Ketcher, D., Reblin, M., & Terrill, A. L. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192013561 · Cited by 17 · see citing works
“For example, meaning-centered group therapy was shown to be effective for cancer survivors to improve personal meaning, psychological well-being and adjustment to cancer in the short term, and over long term, reduce psychological distress [20].”
BackgroundWierstra, I. R., Liefbroer, A. I., Post, L., Tromp, T., & Körver, J. (2021) · Journal of Health Care Chaplaincy · doi:10.1080/08854726.2021.2015055 · Cited by 18 · see citing works
“The intervention called “Precious Memories” is developed for volunteers (Westerhof et al., 2018) and another intervention is developed for psychologists (Van der Spek et al., 2017).”
BackgroundHoltmaat, K., van der Spek, N., Lissenberg-Witte, B. I., BREITBART, W. S., Cuijpers, P. J., & Leeuw, I. M. V. (2017) · Supportive Care in Cancer · doi:10.1007/s00520-017-3757-x · Cited by 17 · see citing works
“The current study is a secondary analysis of the study on the efficacy of MCGP-CS [8] and aims to identifymoderators of the effects ofMCGP-CS on personal meaning, psychological well-being, and distress in cancer survivors who have completed curative treatment and who received their diagnosis in the last 5 years.”
BackgroundMethodResultInfluentialDietrich, N., Estradé, A., & Cruzado, J. A. (2021) · Psicooncología · doi:10.5209/psic.77752 · Cited by 15 · see citing works
“Additional variants of MCP were also developed for various populations and settings, including: grief(14), breast cancer survivors(15), cancer caregivers(16), cancer survivors(17), and adolescents and young adult(18).”
BackgroundJewett, P. I., Vogel, R. I., Galchutt, P. K., Everson‐Rose, S. A., Teoh, D. G. K., Radomski, M. V., & Blaes, A. H. (2022) · Supportive Care in Cancer · doi:10.1007/s00520-021-06784-8 · Cited by 15 · see citing works
Pilz, M. J., Seyringer, S., Hallsson, L. R., Bottomley, A., Jansen, F., King, M. T., Norman, R., Rutten, M. J., Leeuw, I. M. V., Siersema, P. D., et al. (2024) · The European Journal of Health Economics · doi:10.1007/s10198-024-01670-6 · Cited by 14 · see citing works
van Beek, F. E., Wijnhoven, L. M. A., Jansen, F., Custers, J. A. E., Aukema, E. J., Coupé, V. M. H., Cuijpers, P., van der Lee, M. L., Lissenberg-Witte, B. I., Wijnen, B., et al. (2019) · BMC Psychology · doi:10.1186/s40359-019-0368-y · Cited by 13 · see citing works
van Doornik, S. F. W., Glashouwer, K. A., Ostafin, B. D., & de Jong, P. J. (2023) · Behavior Therapy · doi:10.1016/j.beth.2023.05.012 · Cited by 16 · see citing works
Knizek, B. L., Alsaker, S., Hagen, J., Haugan, G., Lehmann, O. V., Nilsen, M., Reidunsdatter, R. J., & Sæther, W. H. (2020) · Encyclopaideia · doi:10.6092/issn.1825-8670/11986 · Cited by 13 · see citing works
Nicklas, L., Albiston, M., Dunbar, M., Gillies, A. C., Hislop, J., Moffat, H., & Thomson, J. (2022) · BMC Health Services Research · doi:10.1186/s12913-022-08158-0 · Cited by 12 · see citing works
Asher, A., Shirazipour, C. H., Capaldi, J. M., Kim, S., Diniz, M. A., Jones, B., & Wertheimer, J. C. (2023) · The Oncologist · doi:10.1093/oncolo/oyad091 · Cited by 11 · see citing works
Wang, S., Zhu, Y., Wang, Z., Zheng, M., Li, X., Zhang, Y., & Wan, H. (2023) · Palliative & Supportive Care · doi:10.1017/s1478951523000998 · Cited by 11 · see citing works
Shaygan, M., Khaki, S., Zarei, D., Moshfeghinia, R., Aeen, F. B., & Sadeghi, Y. (2024) · Supportive Care in Cancer · doi:10.1007/s00520-024-08448-9 · Cited by 11 · see citing works
“9, highlighted that the exclusion of Spek et al. [42] study had a more substantial impact on the overall effect size estimation, rendering it statistically significant (SMD, 3.31 (0.44, 6.17)).”
InfluentialMeaning-centered group psychotherapy in Portuguese cancer patients: A pilot exploratory trial
da Ponte, G., Ouakinin, S., Santo, J. E., Ohunakin, A., Prata, D., Amorim, I., Gameiro, Z., dos Santos, E. S., & BREITBART, W. S. (2021) · Palliative & Supportive Care · doi:10.1017/s1478951521000602 · Cited by 10 · see citing works
“…(respectively); similarly to the original version, and because of its importance described in previous studies, “Historical Sources of Meaning” occupied an entire session (Breitbart et al., 2010, 2012, 2015, 2018; Van der Spek et al., 2014, 2016; Lichtenthal et al., 2015; Rosenfeld et al., 2017).”
Meaning-Centered Psychotherapy
BREITBART, W. S., Lichtenthal, W. G., & Applebaum, A. J. (2022) · Springer eBooks · doi:10.1007/978-3-030-85702-8_23 · Cited by 9 · see citing works
Verdam, M. G. E., van Ballegooijen, W., Holtmaat, K., Knoop, H., Lancee, J., Oort, F. J., Riper, H. M., van Straten, A., Leeuw, I. M. V., de Wit, M., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0252035 · Cited by 9 · see citing works
“The selected sample consisted of data from RCTs on guided internet delivered cognitive behavioural treatment (CBT) for insomnia in the general population with [14] and without [15] elevated depressive symptoms, an RCT on meaning-centered group psychotherapy targeting personal meaning for cancer survivors [16], and fro…”
BackgroundMethodMeaninglessness, Depression and Suicidality: A Review of the Evidence
Allen, A. R. (2022) · Springer eBooks · doi:10.1007/978-3-031-06932-1_16 · Cited by 8 · see citing works
Aydın, R., & Kabukçuoğlu, K. (2023) · Women & Health · doi:10.1080/03630242.2023.2249123 · Cited by 8 · see citing works
Marco, J. H., Llombart, P., Guillén, V., Baños, R. M., Romero, R., Garcia-Conde, A., & Pérez Rodríguez, S. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.892573 · Cited by 7 · see citing works
“Treatment efficacy studies have found a dropout rate of 30% (9), which can interfere with the development of the study as well as the type of statistical analysis that we can perform.”
BackgroundMethodInfluentialPsychological Support for Cancer Patients
Khalid, S., Abbas, I., & Javed, S. (2023) · Cancer treatment and research · doi:10.1007/978-3-031-27156-4_13 · Cited by 7 · see citing works
The Psychological Adaptation Process in Chinese Parent Caregivers of Pediatric Leukemia Patients
Wang, M.-J., Chang, M.-Y., Cheng, M.-Y., & Zhang, R.-X. (2021) · Cancer Nursing · doi:10.1097/ncc.0000000000001034 · Cited by 7 · see citing works
Kita, S., Zonp, Z., & Arnault, D. S. (2022) · Journal of Advanced Nursing · doi:10.1111/jan.15331 · Cited by 7 · see citing works
Chu, H. S., Tak, Y. R., & Kim, S. H. (2018) · Journal of Korean Academy of Nursing · doi:10.4040/jkan.2018.48.4.454 · Cited by 7 · see citing works
“최근 의미중심 대처를 기반으로 한 중재프로그램은 암이나 치매와 같은 만성질환의 가족 돌봄제공자의 정신건강에 긍정적 효과를 보이는 것 으로 보고되고 있다[28,29].”
Wang, S., Zheng, M., Zhu, Y., Zhang, L., Li, X., & Wan, H. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1264257 · Cited by 7 · see citing works
da Ponte, G., Ouakinin, S., Santo, J. E., Amorim, I., Gameiro, Z., Fitz-Henley, M., & BREITBART, W. S. (2020) · Palliative & Supportive Care · doi:10.1017/s147895151900110x · Cited by 6 · see citing works
Hamilton, J. B., & Fluker, W. E. (2021) · Journal of Religion and Health · doi:10.1007/s10943-021-01215-8 · Cited by 6 · see citing works
Schutzeichel, F., Rot, M. A. H., van Doornik, S. F. W., Glashouwer, K. A., Frey, M. I., & de Jong, P. J. (2025) · European Eating Disorders Review · doi:10.1002/erv.3175 · Cited by 5 · see citing works
“Van Doornik and colleagues (2024) adapted existing manuals of meaning‐centered psychotherapies (Breitbart et al. 2018; van der Spek et al. 2017) by (i) reducing the number of sessions, and (ii) updating the content to suit the target demographic of young women with weight and shape concerns.”
Mármol-Pérez, A., Gracia‐Marco, L., Clavero‐Jimeno, A., Amaro‐Gahete, F. J., Ruiz, J. R., & Carneiro‐Barrera, A. (2025) · Annals of Physical and Rehabilitation Medicine · doi:10.1016/j.rehab.2025.101954 · Cited by 5 · see citing works
Yang, Q., Yang, J., Xiang, X., Zhao, Y., Sun, X., Yu, X., Jiang, N., Wang, Y., Ran, H., & Huang, Q. (2024) · Health and Quality of Life Outcomes · doi:10.1186/s12955-024-02283-6 · Cited by 5 · see citing works
“…exemplified by However, we also retrieved a study on resilience-pro-moting interventions with a non-significant effect on improving quality of life [37], which suggests that a one-size-fits-all approach to intervention is likely ineffective since the mediating effect of resilience could vary…”
BackgroundCurrin-McCulloch, J. A., Peterson, D., Kaushik, S. B., & Borrego, J. (2023) · Social Work With Groups · doi:10.1080/01609513.2023.2212391 · Cited by 5 · see citing works
“The intervention draws on the therapeutic factors of group work and topics center on clarifying purpose and spiritual well-being to foster hope and meaning (van der Spek et al., 2017).”
BackgroundAdapting meaning-centered psychotherapy for World Trade Center responders
Duva, M. M., Haugen, P. T., Werth, A. S., Foster, A., Chassman, E., Roberts, K. E., DePierro, J. M., Morales-Miller, M., Lowe, S. M., Pessin, H., et al. (2020) · Palliative & Supportive Care · doi:10.1017/s1478951520000061 · Cited by 5 · see citing works
de Diego‐Cordero, R., Gil, M. A., & Suárez-Reina, P. (2025) · Journal of Religion and Health · doi:10.1007/s10943-025-02525-x · Cited by 4 · see citing works
“Most articles reported statistically significant results, except for the studies by Murdoch et al., 2019; Silverman, 2016; van der Spek et al., 2017; Wright et al., 2022 which showed no effect on hope until some time after the intervention or did not show significant variations in this variable.”
A scoping review of psychosocial oncology interventions promoting posttraumatic growth
Wong, K. L., McClure, K. S., & Psillos, D. E. (2022) · Journal of Psychosocial Oncology Research and Practice · doi:10.1097/or9.0000000000000071 · Cited by 5 · see citing works
Rassoulian, A., & Löffler‐Stastka, H. (2022) · Psychiatria Danubina · doi:10.24869/psyd.2022.398 · Cited by 4 · see citing works
Yager, J., & Kay, J. (2023) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000001657 · Cited by 6 · see citing works
Advances in the Understanding of Demoralization in Oncology and Palliative Care
Grass, L., & de Figueiredo, J. M. (2018) · Psycho-Oncologie · doi:10.3166/pson-2018-0049 · Cited by 4 · see citing works
Tantam, D., & van Deurzen, E. (2019) · doi:10.1002/9781119167198.ch27 · Cited by 4 · see citing works
Embrace subjectivity: existentially-informed clinical psychological science, practice, and teaching
Pashak, T. J., Nelson, O. M., Tunstull, M. D., Vanderstelt, B. H., Nichols, D. P., & Hitt, J. M. (2023) · Clinical Psychologist · doi:10.1080/13284207.2022.2108695 · Cited by 3 · see citing works
Aiello-Puchol, A., & García‐Alandete, J. (2025) · Supportive Care in Cancer · doi:10.1007/s00520-025-09519-1 · Cited by 3 · see citing works
Wong, K. S. S., Ho, M., Hou, T., & Lin, C. (2025) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2025.08.014 · Cited by 3 · see citing works
The Reakiro Care Model for Persons With a Chronic Death Wish: An Epidemiological Study
Vanhie, T., Verdegem, S., Cuypers, A., Bemelmans, L., Onghena, P., & Vandenberghe, J. U. (2025) · Journal of Humanistic Psychology · doi:10.1177/00221678241313088 · Cited by 4 · see citing works
Grossman, M. (2022) · Springer eBooks · doi:10.1007/978-3-031-06101-1_10 · Cited by 3 · see citing works
Purpose in Life and Its Association to Parkinsonism
Koga, H. K., Grodstein, F., Williams, D. R., Buchman, A. S., & Kubzansky, L. D. (2024) · The Journals of Gerontology Series B · doi:10.1093/geronb/gbae026 · Cited by 3 · see citing works
Wang, S., Xu, W., Zhu, Y., Zheng, M., & Wan, H. (2024) · BMJ Open · doi:10.1136/bmjopen-2023-082092 · Cited by 2 · see citing works
Holtmaat, K., van der Spek, N., Rijnhart, J. J. M., Lissenberg-Witte, B. I., BREITBART, W. S., Cuijpers, P. J., & Leeuw, I. M. V. (2024) · Supportive Care in Cancer · doi:10.1007/s00520-024-09039-4 · Cited by 2 · see citing works
“The reduction in depressive symptoms 6 months after MCGP-CS [3] cannot be explained by enhanced meaning and should be confirmed in a future study.”
InfluentialMeaning and Psychedelics in Palliative Care: A Narrative Review
Alexander, W. B., Hansen, E., Anderson, B. T., Zarrabi, A. J., Rogers, A. H., Loewen, G., Ficcaro, Z. R., Alexander, M. H., Schaefer, D., & Case, A. A. (2025) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2025.10.015 · Cited by 2 · see citing works
Chu, Q., Sun, F., Zhu, X.-S., Xia, H., Bian, D.-L., He, G., Yang, J., Zhang, P., & He, Y. (2025) · International Journal of Clinical and Health Psychology · doi:10.1016/j.ijchp.2025.100549 · Cited by 3 · see citing works
“Similarly, in a randomized controlled trial involving cancer patients who had completed primary treatment, van der Spek et al. (2017) found that meaning-centered group psychotherapy — focused on deriving meaning from the cancer experience — was associated with greater reductions in depression…”
Meaning-Centered Psychotherapy
Applebaum, A. J., Lichtenthal, W. G., Pessin, H., & BREITBART, W. S. (2022) · Oxford University Press eBooks · doi:10.1093/med/9780197583838.003.0035 · Cited by 2 · see citing works
- Authors
- van der Spek, N., Vos, J., van Uden-Kraan, C. F., Breitbart, W., Cuijpers, P., Holtmaat, K., Witte, B. I., Tollenaar, R. A. E. M., & Verdonck-de Leeuw, I. M.
- Affiliations
- University of Roehampton (GB)
- Memorial Sloan Kettering Cancer Center (US)
- Vrije Universiteit Amsterdam (NL)
- Leiden University Medical Center (NL)
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2017-04-04
- Volume
- 47
- Issue
- 11
- Pages
- 1990-2001
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- PMC
- PMC5501751
- OpenAlex
- W2604525151
- Cited by
- 135
- References
- 42
- Citations by year
- 2026: 9 · 2025: 11 · 2024: 17 · 2023: 19 · 2022: 28 · 2021: 14 · 2020: 11 · 2019: 9 · 2018: 13 · 2017: 3 · 2016: 1
- FWCI
- 4.34
- Type
- journal article
- Language
- en
- Open access
- green
- research.vu.nl
- Licence
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- VU Research Portal (publishedVersion, other-oa)
- PubMed Central (acceptedVersion)
- Leiden Repository (Leiden University) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Pure Amsterdam UMC (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- National Institutes of Health (R41TR003571)
- National Cancer Institute (P30CA008748)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Social Sciences › Health › Religion, Spirituality, and Psychology
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
- Keywords
- cancer survivors, personal meaning, psychological well-being, mental adjustment to cancer, psychological distress, posttraumatic growth, hopelessness, quality of life
- MeSH terms
- Optimism, Cancer Survivors, Adult, Aged, Anxiety, Depression, Female, Humans, Male, Middle Aged, Personal Satisfaction, Psychotherapy, Group, Quality of Life, Outcome Assessment, Health Care, Hope
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