Early onset dementia: clinical and social aspects
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BACKGROUND: Increasing efforts are being devoted to the study of early onset dementia (EOD), namely dementia in persons under the age of 65. Until recently, it was assumed that dementia occurs primarily among people aged 65 and over. However, since the number of persons with EOD is increasing, its importance as a clinical and social problem is rising accordingly. The aim of the present paper is to summarize research in this area. METHODS: We reviewed the research published to date on EOD, and divided the current body of knowledge into several main sections. RESULTS: The first section focuses on clinical aspects and summarizes findings regarding prevalence, causes, symptoms, diagnosis, and management of persons with EOD. The second section focuses on social aspects related to the cost of care for young people with the disease, the challenges faced by individuals and caregivers, and the services available for this population. Finally, conclusions and future directions are suggested. CONCLUSIONS: Research on EOD is still in its early stages. There is an urgent need to expand research that will lead to more effective diagnosis and management of EOD as well as to the allocation of funds and the development of appropriate services suitable for the unique needs of young people with dementia.
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Less is known about family caregivers of people with early-onset dementia before age 65.
“However, much less is known about the situation of family caregivers of persons with early-onset dementia prior to age 6,7 65”
From The Unique Experience of Spouses in Early-Onset Dementia (2013) · cites this paper as [7]
Dementia diagnosis is always accompanied by psychological upheaval in affected people and their families.
“Once the diagnosis has been established, the advent of dementia is always associated with psychological upheaval in the persons affected and their families.7”
From The Unique Experience of Spouses in Early-Onset Dementia (2013) · cites this paper as [7]
Cites
The prevalence of frontotemporal dementia
Ratnavalli, E., Brayne, C., Dawson, K., & Hodges, J. R. (2002) · Neurology · doi:10.1212/wnl.58.11.1615 · Cited by 1,151 · see citing works
The Prevalence of Dementia in Europe: A Collaborative Study of 1980–1990 Findings
Albert Hofman, D., Rocca, W. A., Brayne, C., Breteler, M. M. B., Clarke, M., Cooper, B. K., Copeland, J. R. M., Dartigues, J. F., Droux, A. D. S., Hagnell, O., et al. (1991) · International Journal of Epidemiology · doi:10.1093/ije/20.3.736 · Cited by 667 · see citing works
The prevalence and causes of dementia in people under the age of 65 years
Harvey, R. J. (2003) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.74.9.1206 · Cited by 650 · see citing works
Heterogeneity in dementia of the Alzheimer type
Mayeux, R. P., Stern, Y., & Spanton, S. (1985) · Neurology · doi:10.1212/wnl.35.4.453 · Cited by 510 · see citing works
Early-Onset Dementia: Frequency and Causes Compared to Late-Onset Dementia
McMurtray, A. M., Clark, D. G., Christine, D., & Mendez, M. F. (2005) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000089546 · Cited by 206 · see citing works
Incidence of early-onset dementias in Cambridgeshire, United Kingdom
Mercy, L., Hodges, J. R., Dawson, K., Barker, R., & Brayne, C. (2008) · Neurology · doi:10.1212/01.wnl.0000334277.16896.fa · Cited by 189 · see citing works
Sampson, E. L., Warren, J. D., & Rossor, M. N. (2004) · Postgraduate Medical Journal · doi:10.1136/pgmj.2003.011171 · Cited by 185 · see citing works
The Accurate Diagnosis of Early-Onset Dementia
Mendez, M. F. (2006) · The International Journal of Psychiatry in Medicine · doi:10.2190/q6j4-r143-p630-kw41 · Cited by 181 · see citing works
The Psychosocial Impact of Young Onset Dementia on Spouses
Kaiser, S., & Panegyres, P. K. (2007) · American Journal of Alzheimer's Disease & Other Dementias® · doi:10.1177/1533317506293259 · Cited by 161 · see citing works
Neuropsychologic Features of Early- and Late-Onset Alzheimer's Disease
Filley, C. M., Kelly, J., & Heaton, R. K. (1986) · Archives of Neurology · doi:10.1001/archneur.1986.00520060038014 · Cited by 138 · see citing works
Arai, A., Matsumoto, T., Ikeda, M., & Arai, Y. (2007) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1935 · Cited by 116 · see citing works
Vascular Dementia: A Contemporary Review of Epidemiology, Diagnosis, Prevention, and Treatment
Nyenhuis, D. L., & Gorelick, P. B. (1998) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1998.tb06015.x · Cited by 115 · see citing works
Early-Onset Dementia Is Associated with Higher Mortality
Koedam, E., Pijnenburg, Y. A. L., Deeg, D. J. H., Baak, M. M. E., van der Vlies, A. E., Scheltens, P., & van der Flier, W. M. (2008) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000149585 · Cited by 106 · see citing works
From pillar to post – a study of younger people with dementia
Williams, T., Dearden, A. M., & Cameron, I. H. (2001) · Psychiatric Bulletin · doi:10.1192/pb.25.10.384 · Cited by 101 · see citing works
Treves, T. A., Korczyn, A. D., Zilber, N., Kahana, E., Leibowitz, Y., Alter, M., & Schoenberg, B. S. (1986) · Archives of Neurology · doi:10.1001/archneur.1986.00520010022014 · Cited by 92 · see citing works
Self-citationPresenile dementia syndromes: an update on taxonomy and diagnosis
Greicius, M. D. (2002) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.72.6.691 · Cited by 85 · see citing works
Incidence and Causes of Nondegenerative Nonvascular Dementia
Knopman, D. S., Petersen, R. C., Cha, R. H., Edland, S. D., & Rocca, W. A. (2006) · Archives of Neurology · doi:10.1001/archneur.63.2.218 · Cited by 83 · see citing works
Neuropsychological patterns of presenile and senile dementia of the Alzheimer type
Loring, D. W., & Largen, J. W. (1985) · Neuropsychologia · doi:10.1016/0028-3932(85)90021-1 · Cited by 70 · see citing works
Cognitive Differences between Early- and Late-Onset Alzheimer's Disease
Licht, E. A., McMurtray, A. M., Saul, R. E., & Mendez, M. F. (2007) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317506299156 · Cited by 68 · see citing works
Course and Causes of Suspected Dementia in Young Adults: A Longitudinal Study
Panegyres, P. K., & Frencham, K. (2007) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317506295887 · Cited by 68 · see citing works
Shinagawa, S., Ikeda, M., Toyota, Y., Matsumoto, T., Matsumoto, N., Mori, T., Ishikawa, T., Fukuhara, R., Komori, K., Hokoishi, K., et al. (2007) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000102596 · Cited by 66 · see citing works
Frequency of early and late‐onset dementias in a Japanese memory disorders clinic
Yokota, O., Sasaki, K., Fujisawa, Y., TAKAHASHI, J. C., Terada, S., Ishihara, T., Nakashima, H., Kugo, A., Ata, T., Ishizu, H., et al. (2005) · European Journal of Neurology · doi:10.1111/j.1468-1331.2005.01072.x · Cited by 64 · see citing works
The Genetics of Very Early Onset Alzheimer Disease
Filley, C. M., Rollins, Y. D., Alan Anderson, C., Arciniegas, D. B., Howard, K. L., Murrell, J. R., Boyer, P. J., Kleinschmidt-DeMasters, B. K., & Ghetti, B. (2007) · Cognitive and Behavioral Neurology · doi:10.1097/wnn.0b013e318145a8c8 · Cited by 53 · see citing works
Prevalence of presenile dementia in a tertiary outpatient clinic
Fujihara, S., Brucki, S. M. D., Rocha, M. S. G., Carvalho, A. A. D. S., & Piccolo, A. C. (2004) · Arquivos de Neuro-Psiquiatria · doi:10.1590/s0004-282x2004000400005 · Cited by 46 · see citing works
Gómez‐Tortosa, E., Ingraham, A. O., Irizarry, M. C., & Hyman, B. T. (1998) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1998.tb06016.x · Cited by 44 · see citing works
Positron Emission Tomography Facilitates Diagnosis of Early-Onset Alzheimer’s Disease
McMurtray, A. M., Licht, E. A., Yeo, T., Krisztal, E., Saul, R. E., & Mendez, M. F. (2007) · European Neurology · doi:10.1159/000109258 · Cited by 33 · see citing works
Services for younger people with dementia
Bentham, P., & Fontaine, J. L. (2005) · Psychiatry · doi:10.1383/psyt.4.2.100.59105 · Cited by 23 · see citing works
Early-onset Alzheimer's disease in Scotland: environmental and familial factors
Whalley, L. J. (2001) · The British Journal of Psychiatry · doi:10.1192/bjp.178.40.s53 · Cited by 21 · see citing works
Early-onset dementia the needs of younger people with dementia in Ireland
Haase, T. (2005) · Lenus, The Irish Health Repository (Dr Steevens Hospital Library) · Cited by 20 · see citing works
Raman, A., Lin, X., Suri, M., Hewitt, M., Constantinescu, C. S., & Phillips, M. F. (2007) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2007.04.013 · Cited by 16 · see citing works
ALZHEIMER DISEASE AND GENETICS
Schutte, D. L. (2006) · AJN American Journal of Nursing · doi:10.1097/00000446-200612000-00018 · Cited by 7 · see citing works
Gonzalez-Salvador (1999) · doi:10.1002/(sici)1099-1166(199909)14:9
Flagged first, then by citations
Cited by
Sorted by citations
Epidemiology of early-onset dementia: a review of the literature
Vieira, R. T., Caixeta, L., Machado, S., Silva, A. C., Nardi, A. E., Arias-Carrión, O., & Carta, M. G. (2013) · Clinical Practice & Epidemiology in Mental Health · doi:10.2174/1745017901309010088 · Cited by 325 · see citing works
Time to diagnosis in young-onset dementia as compared with late-onset dementia
van Vliet, D., de Vugt, M. E., Bakker, C., Pijnenburg, Y. A. L., Vernooij-Dassen, M. J. F. J., Koopmans, R. T. C. M., & Verhey, F. R. J. (2013) · Psychological Medicine · doi:10.1017/s0033291712001122 · Cited by 309 · see citing works
van Vliet, D., de Vugt, M. E., Bakker, C., Koopmans, R. T. C. M., Pijnenburg, Y. A. L., Vernooij-Dassen, M. J. F. J., & Verhey, F. R. J. (2011) · International Psychogeriatrics · doi:10.1017/s1041610211001013 · Cited by 135 · see citing works
Incidence and subtypes of early-onset dementia in a geographically defined general population
Garre‐Olmo, J., Batlle, D. G., Fernández, M., Daniel, F. M., Huélamo, R. D. E., Casadevall, T., Recio, J. T., Estrada, A. T., & Pousa, S. L. (2010) · Neurology · doi:10.1212/wnl.0b013e3181f5d4c4 · Cited by 134 · see citing works
The Unique Experience of Spouses in Early-Onset Dementia
Ducharme, F., Kergoat, M.-J., Antoine, P., Pasquier, F., & Coulombe, R. (2013) · American Journal of Alzheimer's Disease & Other Dementias® · doi:10.1177/1533317513494443 · Cited by 129 · see citing works
The Use of Formal and Informal Care in Early Onset Dementia: Results From the NeedYD Study
Bakker, C., de Vugt, M. E., van Vliet, D., Verhey, F. R. J., Pijnenburg, Y. A. L., Vernooij-Dassen, M. J. F. J., & Koopmans, R. T. C. M. (2013) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2012.10.004 · Cited by 118 · see citing works
Bakker, C., de Vugt, M. E., van Vliet, D., Verhey, F. R. J., Pijnenburg, Y. A. L., Vernooij-Dassen, M. J. F. J., & Koopmans, R. T. C. M. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.09.011 · Cited by 114 · see citing works
The Urban Neighborhood and Cognitive Functioning in Late Middle Age
Aneshensel, C. S., Ko, M., Chodosh, J., & Wight, R. G. (2011) · Journal of Health and Social Behavior · doi:10.1177/0022146510393974 · Cited by 112 · see citing works
Cardiovascular and cognitive fitness at age 18 and risk of early-onset dementia
Nyberg, J., Åberg, M., Schiöler, L., Nilsson, M., Wallin, A., Torén, K., & Kuhn, H. G. (2014) · Brain · doi:10.1093/brain/awu041 · Cited by 109 · see citing works
Experiences of persons with early-onset dementia in everyday life: A qualitative study
Johannessen, A., & Möller, A. R. (2011) · Dementia · doi:10.1177/1471301211430647 · Cited by 97 · see citing works
The Longitudinal Early‐onset Alzheimer's Disease Study (LEADS): Framework and methodology
Apostolova, L. G., Aisen, P. S. S., Eloyan, A., Fagan, A. M., Fargo, K. N., Foroud, T., Gatsonis, C. A., Grinberg, L. T., Jack, C. R., Kramer, J. H., et al. (2021) · Alzheimer s & Dementia · doi:10.1002/alz.12350 · Cited by 92 · see citing works
Arntzen, C., Holthe, T., & Jentoft, R. (2016) · Dementia · doi:10.1177/1471301214532263 · Cited by 93 · see citing works
Amyloid, tau and metabolic PET correlates of cognition in early and late-onset Alzheimer’s disease
Tanner, J. A., Iaccarino, L., Edwards, L., Asken, B. M., Gorno‐Tempini, M. L., Kramer, J. H., Pham, J. Q., Perry, D. C., Possin, K. L., Malpetti, M., et al. (2022) · Brain · doi:10.1093/brain/awac229 · Cited by 88 · see citing works
Cho, H., Choi, J. Y., Lee, S. H., Lee, J. H., Choi, Y.-C., Ryu, Y. H., Lee, M. S., & Lyoo, C. H. (2017) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2017.01.024 · Cited by 83 · see citing works
Unmet support needs of early-onset dementia family caregivers: a mixed-design study
Ducharme, F., Kergoat, M., Coulombe, R., Lévesque, L., Antoine, P., & Pasquier, F. (2014) · BMC Nursing · doi:10.1186/s12912-014-0049-3 · Cited by 79 · see citing works
Understanding the needs and experiences of people with young onset dementia: a qualitative study
Rabanal, L. I., Chatwin, J., Walker, A., OʼSullivan, M., & Williamson, T. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-021166 · Cited by 77 · see citing works
Hewitt, P., Watts, C., Hussey, J. S., Power, K., & Williams, T. I. (2013) · British Journal of Occupational Therapy · doi:10.4276/030802213x13757040168270 · Cited by 74 · see citing works
Sansoni, J., Duncan, C., Grootemaat, P. E., Capell, J. T., Samsa, P., & Westera, A. (2016) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317515619481 · Cited by 72 · see citing works
Bakker, C., de Vugt, M. E., van Vliet, D., Verhey, F. R. J., Pijnenburg, Y. A. L., Vernooij-Dassen, M. J. F. J., Koopmans, R. T. C. M., Koopmans, R. T. C. M., & Rosness, T. A. (2013) · International Psychogeriatrics · doi:10.1017/s1041610213001476 · Cited by 71 · see citing works
Family Caregivers’ Experiences of Caring for a Relative With Younger Onset Dementia
Cabote, C. J., Bramble, M., & McCann, D. (2015) · Journal of Family Nursing · doi:10.1177/1074840715573870 · Cited by 71 · see citing works
Gerritsen, A. A. J., Bakker, C., Verhey, F. R. J., de Vugt, M. E., Melis, R. J. F., Koopmans, R. T. C. M., Oosterveld, S. M., Kessels, R. P. C., Rikkert, M. G. M. O., Hamel, R. E. G., et al. (2016) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2015.11.011 · Cited by 70 · see citing works
The emotional well-being of young people having a parent with younger onset dementia
Hutchinson, K., Roberts, C., Kurrle, S. E., & Daly, M. G. (2014) · Dementia · doi:10.1177/1471301214532111 · Cited by 61 · see citing works
Holthe, T., Jentoft, R., Arntzen, C., & Thorsen, K. (2017) · Disability and Rehabilitation Assistive Technology · doi:10.1080/17483107.2017.1373151 · Cited by 61 · see citing works
Millenaar, J., de Vugt, M. E., Bakker, C., van Vliet, D., Pijnenburg, Y. A. L., Koopmans, R. T. C. M., & Verhey, F. R. J. (2015) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2015.07.005 · Cited by 61 · see citing works
Quality of life in young onset dementia: an updated systematic review
Baptista, M. A. T., Santos, R. L., Kimura, N. R. S., Lacerda, I. B., Johannenssen, A., Barca, M. L., Engedal, K., & Dourado, M. C. N. (2016) · Trends in Psychiatry and Psychotherapy · doi:10.1590/2237-6089-2015-0049 · Cited by 54 · see citing works
Job Loss After Diagnosis of Early-Onset Dementia: A Matched Cohort Study
Sakata, N., & Okumura, Y. (2017) · Journal of Alzheimer s Disease · doi:10.3233/jad-170478 · Cited by 51 · see citing works
Psychosocial impact of early onset dementia among caregivers
Kimura, N. R. S., Maffioletti, V. L. R., Santos, R. L., Baptista, M. A. T., & Dourado, M. C. N. (2015) · Trends in Psychiatry and Psychotherapy · doi:10.1590/2237-6089-2015-0038 · Cited by 49 · see citing works
Young onset dementia – what does the name imply?
Koopmans, R. T. C. M., & Rosness, T. A. (2014) · International Psychogeriatrics · doi:10.1017/s1041610214001574 · Cited by 49 · see citing works
An Integrative Literature Review on the Nomenclature and Definition of Dementia at a Young Age
van de Veen, D., The PRECODE Study Group, Bakker, C., Peetoom, K. K. B., Pijnenburg, Y. A. L., Papma, J. M., de Vugt, M. E., & Koopmans, R. T. C. M. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210458 · Cited by 48 · see citing works
van Vliet, D., Bakker, C., Koopmans, R. T. C. M., Vernooij-Dassen, M. J. F. J., Verhey, F. R. J., & de Vugt, M. E. (2010) · BMC Geriatrics · doi:10.1186/1471-2318-10-13 · Cited by 47 · see citing works
Mulders, A., Fick, I. W. F., Bor, H. H. J., Verhey, F. R. J., Zuidema, S. U., & Koopmans, R. T. C. M. (2016) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2016.01.002 · Cited by 45 · see citing works
The elderly and general anesthesia.
Steinmetz, J., & Rasmussen, L. S. (2010) · PubMed · Cited by 45 · see citing works
Ducharme, F., Lachance, L., Kergoat, M., Coulombe, R., Antoine, P., & Pasquier, F. (2015) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317515578255 · Cited by 44 · see citing works
Holdsworth, K., & McCabe, M. P. (2017) · International Psychogeriatrics · doi:10.1017/s1041610217001806 · Cited by 43 · see citing works
Rosness, T. A., Engedal, K., & Chemali, Z. N. (2016) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988716654986 · Cited by 42 · see citing works
The Needs of Patients With Early Onset Dementia
Armari, E., Jarmolowicz, A. I., & Panegyres, P. K. (2012) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317512466690 · Cited by 35 · see citing works
Larnyo, E., Dai, B., Larnyo, A., Nutakor, J. A., Ampon-Wireko, S., Nkrumah, E. N. K., & Appiah, R. P. (2022) · Healthcare · doi:10.3390/healthcare10020275 · Cited by 35 · see citing works
Alcohol-Related Cognitive Impairment in New South Wales Hospital Patients Aged 50 Years and Over
Draper, B., Karmel, R., Gibson, D. M., Peut, A., & Anderson, P. (2011) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048674.2011.610297 · Cited by 33 · see citing works
Emotional and Psychological Implications of Early AD Diagnosis
Antoine, P., & Pasquier, F. (2013) · Medical Clinics of North America · doi:10.1016/j.mcna.2012.12.015 · Cited by 31 · see citing works
Carr, A. R., Paholpak, P., Daianu, M., Fong, S. S., Mather, M. J., Jimenez, E. E., Thompson, P. M., & Mendez, M. F. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.09.033 · Cited by 31 · see citing works
Development of supportive services for frontotemporal dementias through community engagement
Shnall, A., Agate, A. M., Grinberg, A., Huijbregts, M. P. J., Nguyen, M.-Q., & Chow, T. W. (2013) · International Review of Psychiatry · doi:10.3109/09540261.2013.767780 · Cited by 30 · see citing works
Pang, R. C. K., & Lee, D. (2017) · Dementia · doi:10.1177/1471301217724026 · Cited by 30 · see citing works
Carcaillon‐Bentata, L., Quintin, C., Boussac-Zarebska, M., & Elbaz, A. (2021) · PLoS Medicine · doi:10.1371/journal.pmed.1003801 · Cited by 30 · see citing works
Characteristics of institutionalized young onset dementia patients – the BEYOnD study
Mulders, A., Zuidema, S. U., Verhey, F. R. J., Koopmans, R. T. C. M., Koopmans, R., & Rosness, T. (2014) · International Psychogeriatrics · doi:10.1017/s1041610214001859 · Cited by 29 · see citing works
Differences in Awareness of Disease Between Young-onset and Late-onset Dementia
Baptista, M. A. T., Santos, R. L., Kimura, N. R. S., Marinho, V., Neto, J. P. S., Laks, J., Johannenssen, A., Barca, M. L., Engedal, K., & Dourado, M. C. N. (2019) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0000000000000299 · Cited by 27 · see citing works
Diagnostic experience reported by caregivers of patients with frontotemporal degeneration
Besser, L. M., & Galvin, J. E. (2020) · Neurology Clinical Practice · doi:10.1212/cpj.0000000000000738 · Cited by 27 · see citing works
Resilience in Caregivers of Partners With Young Onset Dementia: A Concept Analysis
Kobiske, K. R., & Bekhet, A. K. (2018) · Issues in Mental Health Nursing · doi:10.1080/01612840.2017.1400625 · Cited by 27 · see citing works
Larochette, C., Wawrziczny, É., Papo, D., Pasquier, F., & Antoine, P. (2019) · Dementia · doi:10.1177/1471301219854643 · Cited by 26 · see citing works
Diagnosing early onset dementia and then what? A frustrating system of aftercare resources
Chemali, Z. N., Tarbi, Schamber, Acar, & Avila-Urizar (2012) · International Journal of General Medicine · doi:10.2147/ijgm.s26523 · Cited by 25 · see citing works
Kimura, N. R. S., Neto, J. P. S., Santos, R. L., Baptista, M. A. T., Portugal, M. D. G., Johannessen, A., Barca, M. L., Engedal, K., Laks, J., Marinho, V., et al. (2020) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988720933355 · Cited by 24 · see citing works
Family carers’ narratives of the financial consequences of young onset dementia
Bayly, M. K., O’Connell, M. E., Kortzman, A., Peacock, S., Morgan, D., & Kirk, A. (2021) · Dementia · doi:10.1177/14713012211009341 · Cited by 25 · see citing works
The Plight of Caring for Young Patients With Frontotemporal Dementia
Chemali, Z. N., Withall, A., & Daffner, K. R. (2010) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317509352335 · Cited by 24 · see citing works
Werner, P., Shpigelman, C., & Raviv-Turgeman, L. (2019) · Scandinavian Journal of Caring Sciences · doi:10.1111/scs.12704 · Cited by 24 · see citing works
Self-citationSangha, J. S., Wally, O. S. D., BANSKOTA, A. H., Stefanova, R., Hafting, J. T., Critchley, A. T., & Prithiviraj, B. (2015) · Marine Drugs · doi:10.3390/md13106407 · Cited by 23 · see citing works
Anaesthesia for the patient with dementia undergoing outpatient surgery
Funder, K. S., Steinmetz, J., & Rasmussen, L. S. (2009) · Current Opinion in Anaesthesiology · doi:10.1097/aco.0b013e328331a4eb · Cited by 23 · see citing works
Managing employees with dementia: a systematic review
Thomson, L., Stanyon, M. R., Dening, T., Heron, R. J. L., & Griffiths, A. (2018) · Occupational Medicine · doi:10.1093/occmed/kqy161 · Cited by 23 · see citing works
Dourado, M. C. N., Laks, J., Kimura, N. R. S., Baptista, M. A. T., Barca, M. L., Engedal, K., Tveit, B., & Johannessen, A. (2017) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4717 · Cited by 22 · see citing works
“My backpack is so heavy”: Experiences of Latino caregivers of family with early‐onset Alzheimer's
Withers, M. H., Cortez‐Sanchez, K., Herrera, J., Ringman, J. M., & Segal‐Gidan, F. (2021) · Journal of the American Geriatrics Society · doi:10.1111/jgs.17091 · Cited by 21 · see citing works
Citizenship as Distributed Achievement: Shaping New Conditions for an Everyday Life with Dementia
Ursin, G., & Lotherington, A. T. (2018) · Scandinavian Journal of Disability Research · doi:10.16993/sjdr.35 · Cited by 21 · see citing works
Anesthesia and the risk of dementia in the elderly
Steinmetz, J., & Rasmussen, L. S. (2018) · La Presse Médicale · doi:10.1016/j.lpm.2018.03.013 · Cited by 20 · see citing works
Functional Status Predicts Awareness in Late-Onset but not in Early-Onset Alzheimer Disease
Dourado, M. C. N., Laks, J., & Mograbi, D. C. (2016) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988716640372 · Cited by 20 · see citing works
Resilience in Carers of People With Young-Onset Alzheimer Disease
Kimura, N. R. S., Neto, J. P. S., Santos, R. L., Baptista, M. A. T., Portugal, G., Johannessen, A., Barca, M. L., Engedal, K., Laks, J., Marinho, V., et al. (2019) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988718824039 · Cited by 19 · see citing works
Stefano, M. D., Esposito, S., Iavarone, A., Mazzi, M. C., Siciliano, M., Buonanno, D., Atripaldi, D., Trojsi, F., & Tedeschi, G. (2022) · Brain Sciences · doi:10.3390/brainsci12030310 · Cited by 19 · see citing works
Zhang, Z., Han, S., Zhu, H., Wang, Q., Cheng, S., Han, Y., Li, F., & Guo, J. (2025) · European Journal of Neurology · doi:10.1111/ene.70116 · Cited by 17 · see citing works
Yeh, T.-S., Wang, J., & Ku, L. E. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-181060 · Cited by 16 · see citing works
Wawrziczny, É., Berna, G., Ducharme, F., Kergoat, M., Pasquier, F., & Antoine, P. (2017) · Aging & Mental Health · doi:10.1080/13607863.2017.1339777 · Cited by 16 · see citing works
Scott, T., Rooney, D., Liddle, J., Mitchell, G. K., Gustafsson, L. A., & Pachana, N. A. (2023) · Age and Ageing · doi:10.1093/ageing/afad109 · Cited by 15 · see citing works
Poole, C., & Patterson, T. G. (2020) · Clinical Gerontologist · doi:10.1080/07317115.2020.1765933 · Cited by 15 · see citing works
Younger onset dementia: a literature review
Sansoni, J., Duncan, C., Grootemaat, P. E., Samsa, P., Capell, J. T., & Westera, A. (2014) · Research Online (University of Wollongong) · Cited by 15 · see citing works
Domains of Awareness in Young and Late Onset Dementia
Baptista, M. A. T., Kimura, N. R. S., Lacerda, I. B., Silva, F. D. O., & Dourado, M. C. N. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201603 · Cited by 13 · see citing works
Smeets, B., Janssen, N., Peetoom, K. K. B., Boots, L. M. M., Bakker, C., & de Vugt, M. E. (2024) · Aging & Mental Health · doi:10.1080/13607863.2024.2345132 · Cited by 13 · see citing works
O’Connor, C. M. C., Fisher, A. C., Cheung, S. C., Caga, J., & Piguet, O. (2021) · Aging & Mental Health · doi:10.1080/13607863.2021.1966744 · Cited by 12 · see citing works
Disease awareness may increase risk of suicide in young onset dementia: A case report
Baptista, M. A. T., Santos, R. L., Kimura, N. R. S., Lacerda, I. B., & Dourado, M. C. N. (2017) · Dementia & Neuropsychologia · doi:10.1590/1980-57642016dn11-030015 · Cited by 12 · see citing works
Between a rock and a hard place: Exploring the service needs of younger people with dementia
Chaston, D. (2011) · Contemporary Nurse · doi:10.5172/conu.2011.130 · Cited by 11 · see citing works
Hvidsten, L., Engedal, K., Selbæk, G., Wyller, T. B., Benth, J. Š., & Kersten, H. (2019) · PLoS ONE · doi:10.1371/journal.pone.0219859 · Cited by 10 · see citing works
Interventions for Persons with Young-Onset Dementia and Their Families: A Scoping Review
Cui, X., Wang, J., Wu, B., Zhao, Q., Tang, X., & Wang, J. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-231006 · Cited by 9 · see citing works
Public Advocacy and Community Engagement
Shnall, A. (2015) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2015.01.006 · Cited by 9 · see citing works
A Systematic Review of the Indirect and Social Costs in Early and Young Onset Dementias
Reina, M. R. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-215204 · Cited by 9 · see citing works
Park, D., Son, K. J., Jeong, E., Kim, H., Lee, S. Y., Kim, J. H., & Kim, H. S. (2022) · Journal of Korean Medical Science · doi:10.3346/jkms.2022.37.e354 · Cited by 8 · see citing works
Brain Imaging in the Differential Diagnosis of Young-Onset Dementias
Shim, H., Ly, M. J., & Tighe, S. K. (2015) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2015.01.007 · Cited by 8 · see citing works
Abdominal obesity and the risk of young-onset dementia in women: a nationwide cohort study
Yang, Y., Han, K., Cheon, D. Y., & Lee, M. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-025-01738-2 · Cited by 7 · see citing works
Reniers, P., Leontjevas, R., Stoyanov, S., Knippenberg, I. A. H., van Lankveld, J. J. D. M., & Gerritsen, D. L. (2019) · International Psychogeriatrics · doi:10.1017/s1041610219001339 · Cited by 6 · see citing works
Young onset dementia : characteristics and impact
van Vliet, D. (2012) · doi:10.26481/dis.20120920dv · Cited by 6 · see citing works
Impact of Mixed Cognitive Intervention Training on Early Onset Dementia
Jeon, B.-R., & Kim, D.-J. (2021) · Osong Public Health and Research Perspectives · doi:10.24171/j.phrp.2021.12.1.05 · Cited by 5 · see citing works
Tang, X., Wang, J., Wu, B., Navarra, A.-M. D., Cui, X., & Wang, J. (2023) · Dementia · doi:10.1177/14713012231193547 · Cited by 5 · see citing works
Race and Ethnicity and Comorbidities Among Medicare Beneficiaries With Young-Onset Dementia
Dai, J., Chau, T., Corrada, M. M., Manson, S. M., O’Connell, J., & Jiang, L. (2025) · JAMA Network Open · doi:10.1001/jamanetworkopen.2025.28001 · Cited by 4 · see citing works
Incidence and Risk of Stroke following Dementia: A Nationwide Cohort Study in South Korea
Kang, C., Lee, S. W., Jung, H., & Bae, Y. (2025) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000549405 · Cited by 4 · see citing works
Abdullah, S., Critchfield, M., Maltby, J., & Mukaetova-Ladinska, E. B. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-215552 · Cited by 4 · see citing works
Blake, C., & Hopper, L. (2021) · International Journal of Care and Caring · doi:10.1332/239788221x16166022097035 · Cited by 5 · see citing works
Binford, S. S., Wallhagen, M. I., & Leutwyler, H. C. (2023) · Journal of Gerontological Nursing · doi:10.3928/00989134-20230707-03 · Cited by 4 · see citing works
The burgeoning interest in young onset dementia: redressing the balance or reinforcing ageism?
Tolhurst, E. (2016) · International Journal of Ageing and Later Life · doi:10.3384/ijal.1652-8670.16302 · Cited by 4 · see citing works
Suzuki, H., Tagai, K., Ono, M., Shimizu, H., Endo, H., Matsumoto, H., Kubota, M., Kataoka, Y., Moriguchi, S., Kurose, S., et al. (2024) · Journal of Alzheimer s Disease · doi:10.1177/13872877241297382 · Cited by 3 · see citing works
Characteristics of Early-Onset Dementia in Chiba Prefecture, Japan: A Multicenter Survey
Hirano, S., Sakakibara, R., Komatsu, N., Shimizu, K., Ishikawa, M., Hosoi, N., Asahi, T., Shuno, T., Sugihara, H., Kanai, S., et al. (2021) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000518294 · Cited by 3 · see citing works
Young onset dementia and driving cessation: a scoping review of lived experiences
Scott, T., Jaymes, R. W. M., McCaul, T., Wilton-Harding, B., & Cations, M. (2024) · BMC Geriatrics · doi:10.1186/s12877-024-05265-x · Cited by 2 · see citing works
Delayed discharge in alcohol-related dementia: consequences and possibilities for improvement
MacPhail, A., McDonough, M., & Ibrahim, J. (2013) · Australian Health Review · doi:10.1071/ah13027 · Cited by 2 · see citing works
Care of Patients and Families at the End of Life
Conceição, S., & Swenson, G. (2019) · doi:10.1093/oso/9780190669607.003.0009 · Cited by 2 · see citing works
de Souza, N. A. P., Neto, J. P. S., & Dourado, M. C. N. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-231324 · Cited by 1 · see citing works
Neuropsychiatric symptoms and awareness in young-and-late-onset dementia
Baptista, M. A. T., Lacerda, I. B., Belfort, T. T., Nogueira, M. M. L., Neto, J. P. S., & Dourado, M. C. N. (2025) · Aging & Mental Health · doi:10.1080/13607863.2025.2515179 · Cited by 1 · see citing works
Koo, J., & Cho, I. (2016) · Exercise Science · doi:10.15857/ksep.2016.25.1.18 · Cited by 1 · see citing works
“Sometimes Life Throws You a Curve Ball”
O’Neil, H. A., & Fletcher, P. C. (2021) · Clinical Nurse Specialist · doi:10.1097/nur.0000000000000635 · Cited by 1 · see citing works
- Authors
- Werner, P., Stein-Shvachman, I., & Korczyn, A. D.
- Affiliations
- University of Haifa (IL)
- Tel Aviv University (IL)
- Corresponding author
- Werner, Perla
- Venue
- International Psychogeriatrics
- Publisher
- Elsevier BV
- Published
- 2009-08
- Volume
- 21
- Issue
- 4
- Pages
- 631-636
- ISSN
- 1041-6102 (ISSN-L)
- OpenAlex
- W2165579423
- Cited by
- 122
- References
- 33
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 7 · 2023: 6 · 2022: 6 · 2021: 14 · 2020: 5 · 2019: 8 · 2018: 6 · 2017: 9 · 2016: 11 · 2015: 8 · 2014: 9 · 2013: 8 · 2012: 5
- FWCI
- 3.49
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Psychogeriatrics (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Neurology › Amyotrophic Lateral Sclerosis Research
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Keywords
- early-onset dementia, prevalence, causes of dementia, clinical symptoms, diagnosis, dementia management, cost of care, caregivers, caregiver challenges, dementia services
- MeSH terms
- Age Factors, Cross-Sectional Studies, Dementia, Health Services Needs and Demand, Humans, Israel, Middle Aged, Risk Factors, Caregivers, Resource Allocation
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