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Cognitive leisure activities and future risk of cognitive impairment and dementia: systematic review and meta-analysis
Open accessAbstract
BACKGROUND: As life expectancies continue to rise, modifiable lifestyle factors that may prevent cognitive decline and dementia in later life become increasingly important in order to maintain quality of life in old age. METHODS: Five meta-analyses were conducted on data from papers identified in a systematic review. Studies were grouped according to outcomes (dementia, cognitive impairment including amnestic Mild Cognitive Impairment (aMCI), Mild Cognitive Impairment (MCI), and cognitive decline) and output (risk (RR), odds (OR), or hazard ratios (HR)). RESULTS: Nineteen studies met our inclusion criteria and quality assessments. Four of five meta-analyses showed significant associations between participation in cognitive leisure activities and reduced risk of cognitive impairment (OR = 0.69, 95% CI: 0.56-0.85) and dementia (HR = 0.58, 95% CI: 0.46-0.74; RR = 0.61, 95% CI: 0.42-0.90; OR = 0.78, 95% CI: 0.67-0.90). However, one pooled analysis of cognitive impairment studies did not reach significance (HR = 0.85, 95% CI: 0.71-1.02). Mentally stimulating leisure activities were significantly associated with later life cognition (β = 0.11, p = 0.05), better memory (β = 0.20, 95% CI: 0.11-0.29), speed of processing (β = 0.37, 95% CI: 0.29-0.45), and executive functioning (β = 0.23, 95% CI: 0.15-0.29), and less decline in overall cognition (β = -0.23, p < 0.01), language (β = -0.11, p < 0.05), and executive functioning (β = -0.13, p < 0.05). Activities were also shown to reduce rate of cognitive decline (estimate = 0.03, SE = 0.01, p = 0.00). CONCLUSIONS: There is increasing evidence that participation in cognitively stimulating leisure activities may contribute to a reduction of risk of dementia and cognitive impairment in later life. Promoting involvement in such activities across lifespan could be an important focus for primary prevention strategies for governments and health services.
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Metadata
- Authors
- Yates, L. A., Ziser, S., Spector, A., & Orrell, M.
- Affiliations
- University of Nottingham (GB)
- University College London (GB)
- Corresponding author
- Yates, Lauren A
- Venue
- International Psychogeriatrics
- Publisher
- Elsevier BV
- Published
- 2016-08-09
- Volume
- 28
- Issue
- 11
- Pages
- 1791-1806
- ISSN
- 1041-6102 (ISSN-L)
- 1741-203X
- OpenAlex
- W2510019780
- Cited by
- 323
- References
- 53
- Citations by year
- 2026: 28 · 2025: 35 · 2024: 33 · 2023: 46 · 2022: 39 · 2021: 43 · 2020: 50 · 2019: 23 · 2018: 20 · 2017: 6
- FWCI
- 2.34
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- International Psychogeriatrics (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- National Institute for Health and Care Research (08/116/06)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Developmental and Educational Psychology › Aging and Gerontology Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
- Keywords
- dementia risk, cognitive impairment, mild cognitive impairment, cognitive decline, cognitive stimulation, leisure, memory, executive function, processing speed, later-life cognition, dementia prevention, lifestyle intervention, older adults, cognitive reserve, brain reserve, neurodegeneration, neuroinflammation, neuroprotection, neuroplasticity, neurogenesis, neurotrophins, neurotensin
- MeSH terms
- Cognition, Dementia, Humans, Leisure Activities, Life Style, Quality of Life, Risk Factors, Risk Reduction Behavior
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