The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Distribution of Novel and Well-Known Poly- and Perfluoroalkyl Substances (PFASs) in Human Serum, Plasma, and Whole Blood
Abstract
Currently, there is limited knowledge on the distribution of poly- and perfluoroalkyl substances (PFASs) in different blood matrices, particularly for novel PFASs such as polyfluoroalkyl phosphate esters (PAPs) and perfluoroalkyl phosphonates (PFPAs). To explore this, serum, plasma, and whole blood from 61 adults in Oslo, Norway were collected. The largest number of PFASs were detected in whole blood. For PAPs and PFPAs, the highest frequencies of detection and concentrations were observed in plasma. PAPs contributed to 8% of total PFASs in plasma (median, 0.81 ng mL –1 ). Perfluorohexylphosphonate (PFHxPA) was the dominant PFPA, regardless of blood matrix. The relative composition profiles of PFASs in blood matrices differed. For some specific PFASs such as perfluorooctanesulfonamide (PFOSA) and perfluorohexanoate (PFHxA), the highest concentrations were observed in whole blood. The PFAS concentration ratios varied between blood matrices, depending on the compounds. However, similar ratios were observed for 6:2 polyfluoroalkyl phosphate diester (6:2diPAP) as well as well-known PFASs such as perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA). Besides the determination of 25 PFASs in human blood, this study also lead to better understanding of biomonitoring data from different blood matrices, which is key knowledge for performing both exposure assessments and epidemiological studies.
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Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
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A Never-Ending Story of Per- and Polyfluoroalkyl Substances (PFASs)?
Wang, Z., DeWitt, J. C., Higgins, C. P., & Cousins, I. T. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.6b04806 · Cited by 1,921
Polyfluorinated Compounds: Past, Present, and Future
Lindstrom, A. B., Strynar, M. J., & Libelo, E. L. (2011) · Environmental Science & Technology · doi:10.1021/es2011622 · Cited by 1,628
Monitoring of Perfluorinated Compounds in Aquatic Biota: An Updated Review: PFCs in Aquatic Biota
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Bioconcentration of perfluorinated alkyl acids: How important is specific binding?
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Analysis of perfluoroalkyl substances in waters from Germany and Spain
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Cited by
Risk to human health related to the presence of perfluoroalkyl substances in food
Panel), E. P. O. C. I. T. F. C. (. C., Schrenk, D., Bignami, M., Bodin, L., Chipman, J. K., del Mazo, J., Grasl‐Kraupp, B., Hogstrand, C., Hoogenboom, L. (., Leblanc, J., et al. (2020) · EFSA Journal · doi:10.2903/j.efsa.2020.6223 · Cited by 989
Self-citationDe Silva, A. O., Armitage, J. M., Bruton, T. A., Dassuncao, C., Heiger-Bernays, W., Hu, X. C., Kärrman, A., Kelly, B., Ng, C., Robuck, A., et al. (2020) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4935 · Cited by 835
Poothong, S., Papadopoulou, E., Padilla-Sánchez, J. A., Thomsen, C., & Haug, L. S. (2020) · Environment International · doi:10.1016/j.envint.2019.105244 · Cited by 357
Self-citationXu, Y., Fletcher, T., Pineda, D., Lindh, C. H., Nilsson, C., Glynn, A., Vogs, C., Norström, K., Lilja, K., Jakobsson, K., et al. (2020) · Environmental Health Perspectives · doi:10.1289/ehp6785 · Cited by 342
Recent advances in the analysis of per- and polyfluoroalkyl substances (PFAS)—A review
Al Amin, M., Sobhani, Z., Liu, Y., Dharmaraja, R., Chadalavada, S., Naidu, R., Chalker, J. M., & Fang, C. (2020) · Environmental Technology & Innovation · doi:10.1016/j.eti.2020.100879 · Cited by 334
Metadata
- Authors
- Poothong, S., Thomsen, C., Padilla-Sanchez, J. A., Papadopoulou, E., & Haug, L. S.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-11-01
- Volume
- 51
- Issue
- 22
- Pages
- 13388-13396
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W2765231636
- Cited by
- 225
- References
- 14
- FWCI
- 6.94
- Type
- journal article
- Language
- en
- Open access
- closed
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