Polyfluorinated Compounds: Past, Present, and Future
Abstract
Interest and concern about polyfluorinated compounds (PFCs), such as perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), and an increasing number of other related compounds is growing as more is learned about these ubiquitous anthropogenic substances. Many of these compounds can be toxic, and they are regularly found in the blood of animals and humans worldwide. A great deal of research has been conducted in this area, but a surprising amount remains unknown about their distribution in the environment and how people ultimately become exposed. The utility of these compounds seems to ensure their continued use in one form or another for the foreseeable future, presenting a long-term challenge to scientists, industry leaders, and public health officials worldwide.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
PFC transport pathways and global fate have not been adequately documented to date.
“Therefore, PFCs are regarded as persistent, bioaccumulative, and potentially hazardous to animals and humans [7, 9]; however, their transport pathways and global fate have not been adequately documented to date [9, 10].”
From Overview of emerging contaminants and associated human health effects (2015) · cites this paper as [10]
Cites
Global Distribution of Perfluorooctane Sulfonate in Wildlife
Giesy, J. P., & Kannan, K. (2001) · Environmental Science & Technology · doi:10.1021/es001834k · Cited by 2,750 · see citing works
Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
Lau, C., Anitole, K., Hodes, C., Lai, D., Pfahles-Hutchens, A., & Seed, J. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm128 · Cited by 2,620 · see citing works
Olsen, G. W., Burris, J. M., Ehresman, D. J., Froehlich, J. W., Seacat, A. M., Butenhoff, J. L., & Zobel, L. R. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10009 · Cited by 2,049 · see citing works
Fluorinated Surfactants and Repellents
(2001) · Textile Research Journal · doi:10.1177/004051750107100823 · Cited by 1,376 · see citing works
Biological Monitoring of Polyfluoroalkyl Substances: A Review
Houde, M., Martin, J. W., Letcher, R. J., Solomon, K. R., & Muir, D. C. G. (2006) · Environmental Science & Technology · doi:10.1021/es052580b · Cited by 1,259 · see citing works
Calafat, A. M., Wong, L.-Y., Kuklenyik, Z., Reidy, J. A., & Needham, L. L. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10598 · Cited by 1,247 · see citing works
Conder, J. M., Hoke, R. A., Wolf, W. D., Russell, M. H., & Buck, R. C. (2008) · Environmental Science & Technology · doi:10.1021/es070895g · Cited by 1,206 · see citing works
A first global production, emission, and environmental inventory for perfluorooctane sulfonate
Paul, A. G., Jones, K. C., & Sweetman, A. J. (2009) · Environmental Science & Technology · doi:10.1021/es802216n · Cited by 1,096 · see citing works
Perfluorooctanesulfonate and related fluorochemicals in human blood from several countries
Kannan, K., Corsolini, S., Falandysz, J., Fillmann, G., Kumar, K. S., Loganathan, B. G., Mohd, M. A., Olivero, J., Wouwe, N. V., Yang, J. H., et al. (2004) · Environmental Science & Technology · doi:10.1021/es0493446 · Cited by 1,056 · see citing works
Perfluorinated compounds – Exposure assessment for the general population in western countries
Fromme, H., Tittlemier, S. A., Völkel, W., Wilhelm, M., & Twardella, D. (2008) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2008.04.007 · Cited by 963 · see citing works
Martin, J. W., Mabury, S. A., Solomon, K. R., & Muir, D. C. G. (2003) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5620220126 · Cited by 960 · see citing works
Compound-specific, quantitative characterization of organic fluorochemicals in biological matrices
Hansen, K. J., Clemen, L. A., Ellefson, M. E., & Johnson, H. O. (2001) · Environmental Science & Technology · doi:10.1021/es001489z · Cited by 923 · see citing works
Trends in Exposure to Polyfluoroalkyl Chemicals in the U.S. Population: 1999−2008
Kato, K., Wong, L.-Y., Jia, L. T., Kuklenyik, Z., & Calafat, A. M. (2011) · Environmental Science & Technology · doi:10.1021/es1043613 · Cited by 777 · see citing works
Epidemiologic Evidence on the Health Effects of Perfluorooctanoic Acid (PFOA)
Steenland, K., Fletcher, T., & Savitz, D. A. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901827 · Cited by 660 · see citing works
A global survey of perfluorinated acids in oceans
Yamashita, N., Kannan, K., Taniyasu, S., Horii, Y., Petrick, G., & Gamo, T. (2005) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2005.04.026 · Cited by 639 · see citing works
Perfluorinated Chemicals and Fetal Growth: A Study within the Danish National Birth Cohort
Fei, C., McLaughlin, J. K., Tarone, R. E., & Olsen, J. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10506 · Cited by 628 · see citing works
Apelberg, B. J., Witter, F. R., Herbstman, J. B., Calafat, A. M., Halden, R. U., Needham, L. L., & Goldman, L. R. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10334 · Cited by 619 · see citing works
Kelly, B. C., Ikonomou, M. G., Blair, J. D., Surridge, B. D., Hoover, D., Grace, R., & Gobas, F. A. P. C. (2009) · Environmental Science & Technology · doi:10.1021/es9003894 · Cited by 568 · see citing works
Nelson, J. W., Hatch, E. E., & Webster, T. F. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901165 · Cited by 538 · see citing works
Perfluoroalkyl Contaminants in a Food Web from Lake Ontario
Martin, J. W., Whittle, D. M., Muir, D. C. G., & Mabury, S. A. (2004) · Environmental Science & Technology · doi:10.1021/es049331s · Cited by 514 · see citing works
Perfluorinated Surfactants in Surface and Drinking Waters (9 pp)
Exner, M., & Färber, H. (2006) · Environmental Science and Pollution Research - International · doi:10.1065/espr2006.07.326 · Cited by 507 · see citing works
Melzer, D., Rice, N., Depledge, M. H., Henley, W. E., & Galloway, T. S. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901584 · Cited by 496 · see citing works
Levels and trends of poly- and perfluorinated compounds in the arctic environment
Butt, C. M., Berger, U., Bossi, R., & Tomy, G. T. (2010) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2010.03.015 · Cited by 488 · see citing works
Do Perfluoroalkyl Compounds Impair Human Semen Quality?
Joensen, U. N., Bossi, R., Leffers, H., Jensen, A. A., Skakkebæk, N. E., & Jørgensen, N. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0800517 · Cited by 413 · see citing works
Sub-chronic dietary toxicity of potassium perfluorooctanesulfonate in rats
Seacat, A. M., Thomford, P. J., Hansen, K. J., Clemen, L. A., Eldridge, S. R., Elcombe, C. R., & Butenhoff, J. L. (2003) · Toxicology · doi:10.1016/s0300-483x(02)00511-5 · Cited by 399 · see citing works
Sepulvado, J. G., Blaine, A. C., Hundal, L. S., & Higgins, C. P. (2011) · Environmental Science & Technology · doi:10.1021/es103903d · Cited by 399 · see citing works
Synthesis of environmentally relevant fluorinated surfactants—a review
Lehmler, H. (2005) · Chemosphere · doi:10.1016/j.chemosphere.2004.11.078 · Cited by 367 · see citing works
Olsen, G. W., Burris, J. M., Burlew, M., & Mandel, J. H. (2003) · Journal of Occupational and Environmental Medicine · doi:10.1097/01.jom.0000052958.59271.10 · Cited by 362 · see citing works
Emmett, E. A., Shofer, F. S., Zhang, H., Freeman, D. W., Desai, C. S., & Shaw, L. M. J. (2006) · Journal of Occupational and Environmental Medicine · doi:10.1097/01.jom.0000232486.07658.74 · Cited by 357 · see citing works
Mechanisms of Extrahepatic Tumor Induction by Peroxisome Proliferators in Male CD Rats
Biegel, L. B., Hurtt, M. E., Frame, S. R., O’Connor, J. C., & Cook, J. C. (2001) · Toxicological Sciences · doi:10.1093/toxsci/60.1.44 · Cited by 349 · see citing works
Diet and particularly seafood are major sources of perfluorinated compounds in humans
Haug, L. S., Thomsen, C., Brantsæter, A. L., Kvalem, H. E., Haugen, M. A., Becher, G., Alexander, J., Meltzer, H. M., & Knutsen, H. K. (2010) · Environment International · doi:10.1016/j.envint.2010.05.016 · Cited by 342 · see citing works
Shoeib, M., Harner, T., Wilford, B. H., Jones, K. C., & Zhu, J. (2005) · Environmental Science & Technology · doi:10.1021/es048340y · Cited by 328 · see citing works
Carryover of Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS) from Soil to Plants
Stahl, T., Heyn, J., Thiele, H.-U., Hüther, J., Failing, K., Georgii, S., & Brunn, H. E. (2008) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-008-9272-9 · Cited by 328 · see citing works
Olsen, G. W., Huang, H.-Y., Helzlsouer, K. J., Hansen, K. J., Butenhoff, J. L., & Mandel, J. H. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.7544 · Cited by 318 · see citing works
Perfluorooctanoate and Perfluorooctane Sulfonate Concentrations in Surface Water in Japan
Saito, N., Harada, K. H., Inoue, K., Sasaki, K., Yoshinaga, T., & Koizumi, A. (2004) · Journal of Occupational Health · doi:10.1539/joh.46.49 · Cited by 302 · see citing works
Haug, L. S., Thomsen, C., & Becher, G. (2009) · Environmental Science & Technology · doi:10.1021/es802827u · Cited by 301 · see citing works
Evidence that there are Two Forms of Fluoride in Human Serum
Taves, D. R. (1968) · Nature · doi:10.1038/2171050b0 · Cited by 253 · see citing works
Shoeib, M., Harner, T., M. Webster, G., & Lee, S. C. (2011) · Environmental Science & Technology · doi:10.1021/es103562v · Cited by 252 · see citing works
Benskin, J. P., Bataineh, M., & Martin, J. W. (2007) · Analytical Chemistry · doi:10.1021/ac070802d · Cited by 251 · see citing works
Thirty years of medical surveillance in perfluooctanoic acid production workers
Costa, G., Sartori, S., & Consonni, D. (2009) · Journal of Occupational & Environmental Medicine · doi:10.1097/jom.0b013e3181965d80 · Cited by 238 · see citing works
Migration of fluorochemical paper additives from food-contact paper into foods and food simulants
Begley, T. H., Hsu, W., Noonan, G., & Diachenko, G. (2008) · Food Additives & Contaminants: Part A · doi:10.1080/02652030701513784 · Cited by 235 · see citing works
Peer Reviewed: Analytical Challenges Hamper Perfluoroalkyl Research
Martin, J. W., Kannan, K., Berger, U., de Voogt, P., Field, J. A., Franklin, J., Giesy, J. P., Harner, T., Muir, D. C. G., Scott, B., et al. (2004) · Environmental Science & Technology · doi:10.1021/es0405528 · Cited by 233 · see citing works
D’eon, J. C., Crozier, P. W., Furdui, V. I., Reiner, E. J., Libelo, E. L., & Mabury, S. A. (2009) · Environmental Science & Technology · doi:10.1021/es900100d · Cited by 214 · see citing works
Self-citationPerfluorinated Compounds in House Dust from Ohio and North Carolina, USA
Strynar, M. J., & Lindstrom, A. B. (2008) · Environmental Science & Technology · doi:10.1021/es7032058 · Cited by 205 · see citing works
Self-citationSakr, C. J., Kreckmann, K. H., Green, J. W., Gillies, P. J., Reynolds, J. L., & Leonard, R. C. (2007) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0b013e318156eca3 · Cited by 191 · see citing works
Sakr, C. J., Leonard, R. C., Kreckmann, K. H., Slade, M. D., & Cullen, M. R. (2007) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0b013e318124a93f · Cited by 189 · see citing works
Mortality Among Employees of a Perfluorooctanoic Acid Production Plant
Gilliland, F. D., & Mandel, J. S. (1993) · Journal of Occupational and Environmental Medicine · doi:10.1097/00043764-199309000-00020 · Cited by 183 · see citing works
Yoo, H., Washington, J. W., Jenkins, T. M., & Ellington, J. J. (2011) · Environmental Science & Technology · doi:10.1021/es102972m · Cited by 182 · see citing works
Mortality of employees of a perfluorooctanesulphonyl fluoride manufacturing facility
Alexander, B. H., Olsen, G. W., Burris, J. M., Mandel, J. H., & Mandel, J. S. (2003) · Occupational and Environmental Medicine · doi:10.1136/oem.60.10.722 · Cited by 179 · see citing works
Ammonium Perfluorooctanoate Production and Occupational Mortality
Lundin, J. I., Alexander, B. H., Olsen, G. W., & Church, T. R. (2009) · Epidemiology · doi:10.1097/ede.0b013e3181b5f395 · Cited by 156 · see citing works
Olsen, G. W., Mair, D. C., Reagen, W. K., Ellefson, M. E., Ehresman, D. J., Butenhoff, J. L., & Zobel, L. R. (2007) · Chemosphere · doi:10.1016/j.chemosphere.2006.12.031 · Cited by 152 · see citing works
Smithwick, M., Norstrom, R. J., Mabury, S. A., Solomon, K. R., Evans, T. J., Stirling, I., Taylor, M. K., & Muir, D. C. G. (2006) · Environmental Science & Technology · doi:10.1021/es051750h · Cited by 150 · see citing works
Cook, J. C., Murray, S. M., Frame, S. R., & Hurtt, M. E. (1992) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(92)90116-a · Cited by 140 · see citing works
van Leeuwen, S. P. J., Kärrman, A., van Bavel, B., de Boer, J., & Lindström, G. (2006) · Environmental Science & Technology · doi:10.1021/es061052c · Cited by 140 · see citing works
RITTER, S. K. (2010) · Chemical & Engineering News Archive · doi:10.1021/cen-v088n005.p012 · Cited by 136 · see citing works
Gordon, S. C. (2010) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2010.09.008 · Cited by 128 · see citing works
CELEBRATING SCIENCE AND ENGINEERING
RITTER, S. (2010) · Chemical & Engineering News · doi:10.1021/cen-v088n041.p012 · Cited by 127 · see citing works
Zushi, Y., Hogarh, J. N., & Masunaga, S. (2011) · Clean Technologies and Environmental Policy · doi:10.1007/s10098-011-0375-z · Cited by 123 · see citing works
Determination of Perfluorinated Compounds in the Upper Mississippi River Basin
Nakayama, S. F., Strynar, M. J., Reiner, J. L., Delinsky, A. D., & Lindstrom, A. B. (2010) · Environmental Science & Technology · doi:10.1021/es100382z · Cited by 122 · see citing works
Self-citationD'eon, J. C., Crozier, P. W., Furdui, V. I., Reiner, E. J., Libelo, E. L., & Mabury, S. A. (2009) · Environmental Toxicology and Chemistry · doi:10.1897/09-048.1 · Cited by 117 · see citing works
Self-citationPerfluorinated Compounds in Fish and Blood of Anglers at Lake Möhne, Sauerland Area, Germany
Hölzer, J., Göen, T., Just, P., Reupert, R., Rauchfuss, K., Kraft, M., Müller, J., & Wilhelm, M. (2011) · Environmental Science & Technology · doi:10.1021/es104391z · Cited by 107 · see citing works
Bladder Cancer in Perfluorooctanesulfonyl Fluoride Manufacturing Workers
Alexander, B. H., & Olsen, G. W. (2007) · Annals of Epidemiology · doi:10.1016/j.annepidem.2007.01.036 · Cited by 104 · see citing works
Keller, J. M., Calafat, A. M., Kato, K., Ellefson, M. E., Reagen, W. K., Strynar, M. J., O’Connell, S. G., Butt, C. M., Mabury, S. A., Small, J. M., et al. (2009) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-009-3222-x · Cited by 97 · see citing works
Self-citationA review of spatial and temporal assessment of PFOS and PFOA contamination in China
Chen, C., Lü, Y., Zhang, X., Geng, J., Wang, T., Shi, Y., Hu, W., & Li, J. (2009) · Chemistry and Ecology · doi:10.1080/02757540902918321 · Cited by 90 · see citing works
Wille, K., Bussche, J. V., Noppe, H., Wulf, E. D., Caeter, P. V., Janssen, C., Brabander, H. F. D., & Vanhaecke, L. (2010) · Journal of Chromatography A · doi:10.1016/j.chroma.2010.03.054 · Cited by 70 · see citing works
Spatial trends of perfluoroalkyl compounds in ringed seals (Phoca hispida) from the Canadian Arctic
Butt, C. M., Mabury, S. A., Kwan, M., Wang, X., & Muir, D. C. G. (2007) · Environmental Toxicology and Chemistry · doi:10.1897/07-428.1 · Cited by 66 · see citing works
Wilhelm, M., Hölzer, J., Dobler, L., Rauchfuss, K., Midasch, O., Kraft, M., Angerer, J., & Wiesmüller, G. A. (2008) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2008.04.008 · Cited by 65 · see citing works
Lindström, G., Kärrman, A., & van Bavel, B. (2008) · Journal of Chromatography A · doi:10.1016/j.chroma.2008.10.091 · Cited by 46 · see citing works
Determination of ten perfluorinated compounds in bluegill sunfish (Lepomis macrochirus) fillets
Delinsky, A. D., Strynar, M. J., Nakayama, S. F., Varns, J. L., Ye, X., McCann, P. J., & Lindstrom, A. B. (2009) · Environmental Research · doi:10.1016/j.envres.2009.08.013 · Cited by 44 · see citing works
Self-citationHighly hydrophobic polyfluorinated azo dyes grafted on surfaces
Soler, R., Salabert, J., Sebastián, R. M., et al. (2011) · Chemical Communications · doi:10.1039/c0cc04695g · Cited by 26 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Rahman, M. F., Peldszus, S., & Anderson, W. B. (2014) · Water Research · doi:10.1016/j.watres.2013.10.045 · Cited by 1,022 · see citing works
Risk to human health related to the presence of perfluoroalkyl substances in food
Panel), E. P. O. C. I. T. F. C. (. C., Schrenk, D., Bignami, M., Bodin, L., Chipman, J. K., del Mazo, J., Grasl‐Kraupp, B., Hogstrand, C., Hoogenboom, L. (., Leblanc, J., et al. (2020) · EFSA Journal · doi:10.2903/j.efsa.2020.6223 · Cited by 989 · see citing works
Barzen-Hanson, K. A., Roberts, S. C., Choyke, S., Oetjen, K., McAlees, A., Riddell, N., McCrindle, R., Ferguson, P. L., Higgins, C. P., & Field, J. A. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.6b05843 · Cited by 873 · see citing works
Accumulation of perfluoroalkyl substances in human tissues
Pérez, F., Nadal, M., Navarro-Ortega, A., Fàbrega, F., Domingo, J. L., Barceló, D., & Farré, M. (2013) · Environment International · doi:10.1016/j.envint.2013.06.004 · Cited by 730 · see citing works
Post, G. B., Cohn, P. D., & Cooper, K. R. (2012) · Environmental Research · doi:10.1016/j.envres.2012.03.007 · Cited by 639 · see citing works
Treatment of poly- and perfluoroalkyl substances in U.S. full-scale water treatment systems
Appleman, T. D., Higgins, C. P., Quiñones, O., Vanderford, B. J., Kolstad, C., Zeigler-Holady, J. C., & Dickenson, E. R. V. (2014) · Water Research · doi:10.1016/j.watres.2013.10.067 · Cited by 585 · see citing works
Zhang, C., Yan, K., Fu, C., Peng, H., Hawker, C. J., & Whittaker, A. K. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00632 · Cited by 493 · see citing works
Johnson, P. I., Sutton, P., Atchley, D. S., Koustas, E., Lam, J., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307893 · Cited by 449 · see citing works
“Environmental Health Perspectives • volume 122 | number 10 | October 2014 1029 there have been inconsistent conclusions about the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 20…”
BackgroundGaballah, S., Swank, A., Sobus, J. R., Howey, X. M., Schmid, J., Catron, T., McCord, J., Hines, E., Strynar, M., & Tal, T. (2020) · Environmental Health Perspectives · doi:10.1289/ehp5843 · Cited by 437 · see citing works
Self-citationWoodruff, T. J., & Sutton, P. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307175 · Cited by 427 · see citing works
Abunada, Z., Alazaiza, M. Y. D., & Bashir, M. J. K. (2020) · Water · doi:10.3390/w12123590 · Cited by 397 · see citing works
Sharma, B. M., Bharat, G. K., Tayal, S., Larssen, T., Bečanová, J., Karásková, P., Whitehead, P. G., Futter, M. N., Butterfield, D., & Nizzetto, L. (2016) · Environmental Pollution · doi:10.1016/j.envpol.2015.10.050 · Cited by 353 · see citing works
Koustas, E., Lam, J., Sutton, P., Johnson, P. I., Atchley, D. S., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307177 · Cited by 349 · see citing works
Review of the fate and transformation of per- and polyfluoroalkyl substances (PFASs) in landfills
Hamid, H., Li, L. Y., & Grace, J. R. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2017.12.030 · Cited by 343 · see citing works
Coggan, T. L., Moodie, D., Kolobaric, A., Szabo, D., Shimeta, J., Crosbie, N. D., Lee, E., Fernandes, M., & Clarke, B. O. (2019) · Heliyon · doi:10.1016/j.heliyon.2019.e02316 · Cited by 327 · see citing works
Blaine, A. C., Rich, C. D., Hundal, L. S., Lau, C., Mills, M. A., Harris, K. M., & Higgins, C. P. (2013) · Environmental Science & Technology · doi:10.1021/es403094q · Cited by 325 · see citing works
Per- and polyfluorinated substances (PFASs): Environmental challenges
Krafft, M. P., & Riess, J. G. (2015) · Current Opinion in Colloid & Interface Science · doi:10.1016/j.cocis.2015.07.004 · Cited by 294 · see citing works
Hepburn, E., Madden, C., Szabo, D., Coggan, T. L., Clarke, B., & Currell, M. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.02.018 · Cited by 289 · see citing works
Belkouteb, N., Franke, V., McCleaf, P., Köhler, S., & Ahrens, L. (2020) · Water Research · doi:10.1016/j.watres.2020.115913 · Cited by 255 · see citing works
Zhao, L., Bian, J., Zhang, Y., Zhu, L., & Liu, Z. (2014) · Chemosphere · doi:10.1016/j.chemosphere.2014.03.098 · Cited by 247 · see citing works
Høisæter, Å., Pfaff, A., & Breedveld, G. D. (2019) · Journal of Contaminant Hydrology · doi:10.1016/j.jconhyd.2019.02.010 · Cited by 243 · see citing works
Blake, B. E., Pinney, S. M., Hines, E. P., Fenton, S. E., & Ferguson, K. K. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.07.042 · Cited by 236 · see citing works
Overview of emerging contaminants and associated human health effects
Lei, M., Zhang, L., Lei, J., Zong, L., Li, J., Wu, Z., & Wang, Z. (2015) · BioMed Research International · doi:10.1155/2015/404796 · Cited by 231 · see citing works
Blaine, A. C., Rich, C. D., Sedlacko, E. M., Hyland, K. C., Stushnoff, C., Dickenson, E. R. V., & Higgins, C. P. (2014) · Environmental Science & Technology · doi:10.1021/es504150h · Cited by 229 · see citing works
Flores, C., Ventura, F., Martin-Alonso, J., & Caixach, J. (2013) · Science of The Total Environment · doi:10.1016/j.scitotenv.2013.05.026 · Cited by 221 · see citing works
Ojo, A. F., Peng, C., & Ng, J. C. (2021) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.124863 · Cited by 221 · see citing works
Newton, S., McMahen, R., Stoeckel, J. A., Chislock, M., Lindstrom, A., & Strynar, M. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.6b05330 · Cited by 217 · see citing works
Self-citationLam, J., Koustas, E., Sutton, P., Johnson, P. I., Atchley, D. S., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307923 · Cited by 214 · see citing works
Galloway, J. E., Moreno, A. V. P., Lindstrom, A. B., Strynar, M. J., Newton, S., May, A. A., & Weavers, L. K. (2020) · Environmental Science & Technology · doi:10.1021/acs.est.9b07384 · Cited by 216 · see citing works
Self-citationSchultes, L., Vestergren, R., Volkova, K., Westberg, E., Jacobson, T., & Benskin, J. P. (2018) · Environmental Science: Processes & Impacts · doi:10.1039/c8em00368h · Cited by 193 · see citing works
Zhang, C., Hopkins, Z. R., McCord, J., Strynar, M. J., & Knappe, D. R. U. (2019) · Environmental Science & Technology Letters · doi:10.1021/acs.estlett.9b00525 · Cited by 202 · see citing works
Self-citationPerfluorinated and Polyfluorinated Compounds in Lake Food Webs from the Canadian High Arctic
Lescord, G. L., Kidd, K. A., De Silva, A. O., Williamson, M., Spencer, C., Wang, X., & Muir, D. C. G. (2015) · Environmental Science & Technology · doi:10.1021/es5048649 · Cited by 192 · see citing works
Breastfeeding as an exposure pathway for perfluorinated alkylates
Mogensen, U. B., Grandjean, P., Nielsen, F., Weihe, P., & Budtz-Jørgensen, E. (2015) · Environmental Science & Technology · doi:10.1021/acs.est.5b02237 · Cited by 190 · see citing works
Castiglioni, S., Valsecchi, S., Polesello, S., Rusconi, M., Melis, M., Palmiotto, M., Manenti, A., Davoli, E., & Zuccato, E. (2015) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2014.06.007 · Cited by 186 · see citing works
PFOS and PFC releases and associated pollution from a PFC production plant in Minnesota (USA)
Oliaei, F., Kriens, D., Weber, R., & Watson, A. (2013) · Environmental Science and Pollution Research · doi:10.1007/s11356-012-1275-4 · Cited by 188 · see citing works
McCord, J., & Strynar, M. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.8b06017 · Cited by 183 · see citing works
Self-citationAhmed, M. B., Johir, M. A. H., McLaughlan, R., Nguyen, L. N., Xu, B., & Nghiem, L. D. (2020) · Science of The Total Environment · doi:10.1016/j.scitotenv.2020.141251 · Cited by 177 · see citing works
Meneguzzi, A., Fava, C., Castelli, M., & Minuz, P. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.706352 · Cited by 174 · see citing works
Preston, E. V., Webster, T. F., Claus Henn, B., McClean, M. D., Gennings, C., Oken, E., Rifas-Shiman, S. L., Pearce, E. N., Calafat, A. M., Fleisch, A. F., et al. (2020) · Environment International · doi:10.1016/j.envint.2020.105728 · Cited by 169 · see citing works
Starnes, H. M., Rock, K. D., Jackson, T. W., & Belcher, S. M. (2022) · Frontiers in Toxicology · doi:10.3389/ftox.2022.881584 · Cited by 166 · see citing works
Goodrow, S. M., Ruppel, B., Lippincott, R. L., Post, G. B., & Procopio, N. A. (2020) · Science of The Total Environment · doi:10.1016/j.scitotenv.2020.138839 · Cited by 165 · see citing works
Dietary Habits Related to Food Packaging and Population Exposure to PFASs
Susmann, H. P., Schaider, L. A., Rodgers, K. M., & Rudel, R. A. (2019) · Environmental Health Perspectives · doi:10.1289/ehp4092 · Cited by 165 · see citing works
Ionic Fluorogels for Remediation of Per- and Polyfluorinated Alkyl Substances from Water
Kumarasamy, E., Manning, I. M., Collins, L. B., Coronell, O., & Leibfarth, F. A. (2020) · ACS Central Science · doi:10.1021/acscentsci.9b01224 · Cited by 162 · see citing works
Brown-Leung, J. M., & Cannon, J. R. (2022) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.2c00072 · Cited by 164 · see citing works
Discovery of a Novel Polyfluoroalkyl Benzenesulfonic Acid around Oilfields in Northern China
Xu, L., Shi, Y., Li, C., Song, X., Qin, Z., Cao, D., & Cai, Y. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.7b04332 · Cited by 148 · see citing works
Post, G. B., Gleason, J. A., & Cooper, K. R. (2017) · PLOS Biology · doi:10.1371/journal.pbio.2002855 · Cited by 145 · see citing works
The occurrence, distribution, and risks of PFAS at AFFF-impacted sites in Finland
Reinikainen, J., Perkola, N., Äystö, L., & Sorvari, J. (2022) · Science of The Total Environment · doi:10.1016/j.scitotenv.2022.154237 · Cited by 142 · see citing works
D’Ambro, E. L., Pye, H. O. T., Bash, J. O., Bowyer, J., Allen, C., Efstathiou, C., Gilliam, R. C., Reynolds, L., Talgo, K., & Murphy, B. N. (2021) · Environmental Science & Technology · doi:10.1021/acs.est.0c06580 · Cited by 145 · see citing works
Pan, C.-G., Ying, G.-G., Zhao, J.-L., Liu, Y.-S., Jiang, Y.-X., & Zhang, Q.-Q. (2014) · Science of The Total Environment · doi:10.1016/j.scitotenv.2014.06.033 · Cited by 143 · see citing works
Development of PBPK models for PFOA and PFOS for human pregnancy and lactation life stages
Loccisano, A. E., Longnecker, M. P., Campbell, J. L., Andersen, M. E., & Clewell, H. J. (2013) · Journal of Toxicology and Environmental Health, Part A · doi:10.1080/15287394.2012.722523 · Cited by 141 · see citing works
Brown, J. B., Conder, J. M., Arblaster, J. A., & Higgins, C. P. (2020) · Environmental Science & Technology · doi:10.1021/acs.est.0c03411 · Cited by 135 · see citing works
Greaves, A. K., Letcher, R. J., Sonne, C., Dietz, R., & Born, E. W. (2012) · Environmental Science & Technology · doi:10.1021/es303400f · Cited by 127 · see citing works
Wang, B., Yao, Y., Chen, H., Chang, S., Tian, Y., & Sun, H. (2020) · Science of The Total Environment · doi:10.1016/j.scitotenv.2019.135832 · Cited by 127 · see citing works
Occurrence of perfluorinated compounds in raw water from New Jersey public drinking water systems
Post, G. B., Louis, J. B., Lippincott, R. L., & Procopio, N. A. (2013) · Environmental Science & Technology · doi:10.1021/es402884x · Cited by 130 · see citing works
Graber, J. M., Alexander, C., Laumbach, R. J., Black, K., Strickland, P. O., Georgopoulos, P. G., Marshall, E. G., Shendell, D. G., Alderson, D., Mi, Z., et al. (2019) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/s41370-018-0096-z · Cited by 118 · see citing works
PIGE as a screening tool for Per- and polyfluorinated substances in papers and textiles
Ritter, E. E., Dickinson, M. E., Harron, J. P., Lunderberg, D. M., DeYoung, P. A., Robel, A. E., Field, J. A., & Peaslee, G. F. (2017) · Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms · doi:10.1016/j.nimb.2017.05.052 · Cited by 123 · see citing works
Qian, S., Lu, H., Xiong, T., Zhi, Y., Munoz, G., Zhang, C., Li, Z., Liu, C., Li, W., Wang, X., et al. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.2c06883 · Cited by 122 · see citing works
Eggers Pedersen, K., Basu, N., Letcher, R., Greaves, A. K., Sonne, C., Dietz, R., & Styrishave, B. (2015) · Environmental Research · doi:10.1016/j.envres.2015.01.015 · Cited by 116 · see citing works
Jantzen, C. E., Annunziato, K. M., & Cooper, K. R. (2016) · Aquatic Toxicology · doi:10.1016/j.aquatox.2016.09.011 · Cited by 113 · see citing works
Wagner, A., Raue, B., Brauch, H.-J., Worch, E., & Lange, F. T. (2013) · Journal of Chromatography A · doi:10.1016/j.chroma.2013.04.051 · Cited by 107 · see citing works
Jarvis, A. L., Justice, J. R., Elias, M. C., Schnitker, B., & Gallagher, K. (2021) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5147 · Cited by 105 · see citing works
Ruan, T., & Jiang, G. (2017) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2017.07.024 · Cited by 94 · see citing works
Lee, Y. J., Jung, H. W., Kim, H. Y., Choi, Y.-J., & Lee, Y. A. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.683297 · Cited by 96 · see citing works
Wang, Y., Shi, Y., Vestergren, R., Zhou, Z., Liang, Y., & Cai, Y. (2018) · Science of The Total Environment · doi:10.1016/j.scitotenv.2018.04.279 · Cited by 94 · see citing works
Association of perfluoroalkyl substances exposure with impaired lung function in children
Qin, X.-D., Qian, Z. (., Dharmage, S. C., Perret, J., Geiger, S. D., Rigdon, S. E., Howard, S., Zeng, X.-W., Hu, L.-W., Yang, B.-Y., et al. (2017) · Environmental Research · doi:10.1016/j.envres.2017.01.025 · Cited by 90 · see citing works
Toxicokinetics of Seven Perfluoroalkyl Sulfonic and Carboxylic Acids in Pigs Fed a Contaminated Diet
Numata, J., Kowalczyk, J., Adolphs, J., Ehlers, S., Schafft, H., Fuerst, P., Müller-Graf, C., Lahrssen-Wiederholt, M., & Greiner, M. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf405827u · Cited by 92 · see citing works
Liu, Y., Robey, N. M., Bowden, J. A., Tolaymat, T. M., da Silva, B. F., Solo-Gabriele, H. M., & Townsend, T. G. (2021) · Environmental Science & Technology Letters · doi:10.1021/acs.estlett.0c00819 · Cited by 89 · see citing works
Chi, Q., Li, Z., Huang, J., Ma, J., & Wang, X. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.01.152 · Cited by 87 · see citing works
McKenzie, E. R., Siegrist, R. L., McCray, J. E., & Higgins, C. P. (2015) · Environmental Science & Technology · doi:10.1021/es503676p · Cited by 84 · see citing works
Per- and polyfluoroalkyl substances in selected sewage sludge in Nigeria
Sindiku, O., Orata, F., Weber, R., & Osibanjo, O. (2013) · Chemosphere · doi:10.1016/j.chemosphere.2013.04.010 · Cited by 82 · see citing works
Zhang, H., Wen, B., Hu, X., Wu, Y., Pan, Y., Huang, H., Liu, L., & Zhang, S. (2016) · Environmental Science & Technology · doi:10.1021/acs.est.6b03734 · Cited by 81 · see citing works
Perfluorinated Compounds in Serum and Urine Samples from Children Aged 5-13 Years in South Korea
Kim, D.-H., Lee, M.-Y., & Oh, J.-E. (2014) · Environmental Pollution · doi:10.1016/j.envpol.2014.05.024 · Cited by 78 · see citing works
Berk, M., Williams, L. J., Andreazza, A. C., Pasco, J. A., Dodd, S., Jacka, F. N., Moylan, S., Reiner, E. J., & Magalhaes, P. V. S. (2014) · BMJ Open · doi:10.1136/bmjopen-2014-005142 · Cited by 77 · see citing works
Willach, S., Brauch, H.-J., & Lange, F. T. (2016) · Chemosphere · doi:10.1016/j.chemosphere.2015.11.113 · Cited by 71 · see citing works
Liu, X., Guo, Z., Krebs, K. A., Pope, R. H., & Roache, N. F. (2014) · Chemosphere · doi:10.1016/j.chemosphere.2013.10.001 · Cited by 71 · see citing works
Jeong, Y., Da Silva, K. M., Iturrospe, E., Fuiji, Y., Boogaerts, T., van Nuijs, A. L. N., Koelmel, J., & Covaci, A. (2022) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2022.129378 · Cited by 76 · see citing works
Chen, Y., Zhang, H., Liu, Y., Bowden, J. A., Tolaymat, T. M., Townsend, T. G., & Solo-Gabriele, H. M. (2023) · Chemosphere · doi:10.1016/j.chemosphere.2023.137903 · Cited by 69 · see citing works
Mechanism and implication of the sorption of perfluorooctanoic acid by varying soil size fractions
Xiang, L., Xiao, T., Yu, P.-F., Zhao, H.-M., Mo, C.-H., Li, Y.-W., Li, H., Cai, Q.-Y., Zhou, D.-M., & Wong, M.-H. (2018) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.8b03492 · Cited by 67 · see citing works
Vertical transport and sinks of perfluoroalkyl substances in the global open ocean
González-Gaya, B., Casal, P., Jurado, E., Dachs, J., & Jiménez, B. (2019) · Environmental Science: Processes & Impacts · doi:10.1039/c9em00266a · Cited by 67 · see citing works
Yu, X., Nishimura, F., & Hidaka, T. (2018) · Science of The Total Environment · doi:10.1016/j.scitotenv.2017.08.075 · Cited by 54 · see citing works
Chen, Y., Zhang, H., Liu, Y., Bowden, J. A., Tolaymat, T. M., Townsend, T. G., & Solo-Gabriele, H. M. (2022) · Waste Management · doi:10.1016/j.wasman.2022.08.024 · Cited by 54 · see citing works
Chen, L., Chen, D., Zhou, S., Lin, J., Liu, Y., Huang, X., Lin, Q., Morel, J. L., Ni, Z., Wang, S., et al. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.2c09226 · Cited by 51 · see citing works
Comprehensive Emerging Chemical Discovery: Novel Polyfluorinated Compounds in Lake Michigan Trout
Fakouri Baygi, S., Crimmins, B. S., Hopke, P. K., & Holsen, T. M. (2016) · Environmental Science & Technology · doi:10.1021/acs.est.6b01349 · Cited by 49 · see citing works
Mumtaz, M., Bao, Y., Li, W., Kong, L., Huang, J., & Yu, G. (2019) · Frontiers of Environmental Science & Engineering · doi:10.1007/s11783-019-1145-0 · Cited by 45 · see citing works
Gao, Y., Li, X., Li, X., Zhang, Q., & Li, H. (2018) · Journal of Chromatography B · doi:10.1016/j.jchromb.2018.03.008 · Cited by 46 · see citing works
Engineering artificial communities for enhanced FTOH degradation
Lewis, M., Kim, M.-H., Wang, N., & Chu, K.-H. (2016) · Science of The Total Environment · doi:10.1016/j.scitotenv.2016.07.223 · Cited by 44 · see citing works
Ducatman, A., Luster, M., & Fletcher, T. (2021) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2021.103650 · Cited by 42 · see citing works
Zhang, L., Liang, J., & Gao, A. (2023) · Chemosphere · doi:10.1016/j.chemosphere.2023.137748 · Cited by 41 · see citing works
Balgooyen, S., & Remucal, C. K. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.2c06600 · Cited by 38 · see citing works
Strong bioaccumulation of a wide variety of PFAS in a contaminated terrestrial and aquatic ecosystem
Gkika, I. S., Arie Vonk, J., ter Laak, T. L., van Gestel, C. A. M., Dijkstra, J., Groffen, T., Bervoets, L., & Kraak, M. H. S. (2025) · Environment International · doi:10.1016/j.envint.2025.109629 · Cited by 38 · see citing works
Li, H., Chen, J., Lu, J., Yang, J., Tan, Z., Li, L., Xiao, F., An, Z., Ma, C., Liu, Y., et al. (2023) · Chemosphere · doi:10.1016/j.chemosphere.2022.137464 · Cited by 35 · see citing works
Per- and polyfluoroalkyl substances (PFAS) in the marine environment: An overview and prospects
Wang, Q., Shao, Y., Leung, K. M. Y., Lam, P. K. S., & Ruan, Y. (2025) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2025.117993 · Cited by 38 · see citing works
Manning, I. M., Guan Pin Chew, N., Macdonald, H. P., Miller, K. E., Strynar, M. J., Coronell, O., & Leibfarth, F. A. (2022) · Angewandte Chemie · doi:10.1002/ange.202208150 · Cited by 31 · see citing works
Self-citationZhang, H., Chen, Y., Liu, Y., Bowden, J. A., Tolaymat, T. M., Townsend, T. G., & Solo-Gabriele, H. M. (2023) · Chemosphere · doi:10.1016/j.chemosphere.2023.138541 · Cited by 31 · see citing works
Strong Base Anion Exchange Selectivity of Nine Perfluoroalkyl Chemicals Relevant to Drinking Water
Wahman, D. G., Smith, S. J., Kleiner, E. J., Abulikemu, G., Stebel, E. K., Gray, B. N., Crone, B. C., Taylor, R. D., Womack, E. A., Gastaldo, C. X., et al. (2023) · ACS ES&T Water · doi:10.1021/acsestwater.3c00396 · Cited by 30 · see citing works
Yang, M., Su, W., Li, H., Li, L., An, Z., Xiao, F., Liu, Y., Zhang, X., Liu, X., Guo, H., et al. (2023) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.115473 · Cited by 23 · see citing works
Wang, W., Yuan, S., & Kwon, J.-H. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-21886-4 · Cited by 21 · see citing works
Alghamdi, W., Marchiandi, J., Szabo, D., Samandra, S., & Clarke, B. O. (2022) · Journal of Hazardous Materials Advances · doi:10.1016/j.hazadv.2022.100167 · Cited by 19 · see citing works
Qiao, W., Li, J., Luo, L., Peng, W., Wang, X., Jin, R., & Li, J. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.117436 · Cited by 16 · see citing works
Chen, Y., Zhang, H., Liu, Y., Bowden, J. A., Townsend, T. G., & Solo-Gabriele, H. M. (2024) · Chemosphere · doi:10.1016/j.chemosphere.2024.141719 · Cited by 12 · see citing works
- Authors
- Lindstrom, A. B., Strynar, M. J., & Libelo, E. L.
- Affiliations
- Environmental Protection Agency (US)
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-09-09
- Volume
- 45
- Issue
- 19
- Pages
- 7954-7961
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W2039774973
- Cited by
- 1,628
- References
- 71
- Citations by year
- 2026: 117 · 2025: 164 · 2024: 148 · 2023: 130 · 2022: 155 · 2021: 140 · 2020: 138 · 2019: 118 · 2018: 102 · 2017: 72 · 2016: 73 · 2015: 97 · 2014: 75 · 2013: 55 · 2012: 38
- Type
- other
- Language
- en
- Open access
- closed
- Locations
- Environmental Science & Technology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Environmental Protection Agency
- Topics
- Physical Sciences › Environmental Science › Environmental Chemistry › Per- and polyfluoroalkyl substances research
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Fluorine in Organic Chemistry
- Keywords
- polyfluorinated compounds, PFOS, perfluorooctanoic acid, PFAS, environmental persistence, human exposure, toxicity, environmental distribution, anthropogenic pollutants
- MeSH terms
- Animals, Environmental Exposure, Environmental Monitoring, Fluorocarbons, Humans, History, 20th Century
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review