Cited by 1,628Per- and polyfluoroalkyl substances researchToxic Organic Pollutants ImpactFluorine in Organic Chemistry

Polyfluorinated Compounds: Past, Present, and Future

Lindstrom, Andrew B., Strynar, Mark J., Libelo, E. Laurence·2011·Environmental Science & Technology

Abstract

Interest and concern about polyfluorinated compounds (PFCs), such as perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), and an increasing number of other related compounds is growing as more is learned about these ubiquitous anthropogenic substances. Many of these compounds can be toxic, and they are regularly found in the blood of animals and humans worldwide. A great deal of research has been conducted in this area, but a surprising amount remains unknown about their distribution in the environment and how people ultimately become exposed. The utility of these compounds seems to ensure their continued use in one form or another for the foreseeable future, presenting a long-term challenge to scientists, industry leaders, and public health officials worldwide.

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Registry

Crossref · 10.1021/es2011622

Cites

71 of 71 references verified0 citation errors · 0 not checkable

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  • PFC transport pathways and global fate have not been adequately documented to date.

    “Therefore, PFCs are regarded as persistent, bioaccumulative, and potentially hazardous to animals and humans [7, 9]; however, their transport pathways and global fate have not been adequately documented to date [9, 10].”

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Authors
Lindstrom, A. B., Strynar, M. J., & Libelo, E. L.
Affiliations
Environmental Protection Agency (US)
Venue
Environmental Science & Technology
Published
2011-09-09
Volume
45
Issue
19
Pages
7954-7961
ISSN
  • 0013-936X (ISSN-L)
  • 1520-5851
OpenAlex
W2039774973
Cited by
1,628
References
71
Citations by year
2026: 117 · 2025: 164 · 2024: 148 · 2023: 130 · 2022: 155 · 2021: 140 · 2020: 138 · 2019: 118 · 2018: 102 · 2017: 72 · 2016: 73 · 2015: 97 · 2014: 75 · 2013: 55 · 2012: 38
Type
other
Language
en
Open access
closed
Locations
  • Environmental Science & Technology (publishedVersion)
  • PubMed (publishedVersion)
Funders
U.S. Environmental Protection Agency
Topics
  • Physical Sciences › Environmental Science › Environmental Chemistry › Per- and polyfluoroalkyl substances research
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Fluorine in Organic Chemistry
Keywords
polyfluorinated compounds, PFOS, perfluorooctanoic acid, PFAS, environmental persistence, human exposure, toxicity, environmental distribution, anthropogenic pollutants
MeSH terms
Animals, Environmental Exposure, Environmental Monitoring, Fluorocarbons, Humans, History, 20th Century

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