The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.
Yolk–Shell Structured Au Nanostar@Metal–Organic Framework for Synergistic Chemo-photothermal Therapy in the Second Near-Infrared Window
Abstract
Light-sensitive yolk-shell nanoparticles (YSNs) as remote-controlled and stimuli-responsive theranostic platforms provide an attractive method for synergistic cancer therapy. Herein, a kind of novel stimuli-responsive multifunctional YSNs has been successfully constructed by integrating star-shaped gold (Au star) nanoparticles as the second near-infrared (NIR-II) photothermal yolks and biodegradable crystalline zeolitic imidazolate framework-8 (ZIF-8) as the shells. In this platform, a chemotherapeutic drug (doxorubicin hydrochloride, DOX) was encapsulated into the cavity, which can show the behavior of controlled release due to the degradation process of ZIF-8 in the mildly acidic tumor microenvironment. Upon the 1064 nm (NIR-II biowindow) laser irradiation, gold nanostar@ZIF-8 (Au@MOF) nanoparticles exhibited outstanding synergistic anticancer effect based on their photothermal and promoted cargo release properties. Moreover, the strong NIR region absorbance endows the Au@MOF of NIR thermal imaging and photoacoustic (PA) imaging properties. This work contributes to design a stimuli-responsive "all-in-one" nanocarrier that realizes bimodal imaging diagnosis and chemo-photothermal synergistic therapy.
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Cited by
Second near-infrared photothermal materials for combinational nanotheranostics
Xu, C., & Pu, K. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00664e · Cited by 941
Multifunctional metal–organic framework heterostructures for enhanced cancer therapy
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Gathering brings strength: How organic aggregates boost disease phototheranostics
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Advances in Local Drug Delivery for Periodontal Treatment: Present Strategies and Future Directions
Nakajima, M., Yanagawa, M., Takikawa, H., Thien, T. T., Zegarra-Caceres, L., Yan, C., & Tabeta, K. (2025) · Biomolecules · doi:10.3390/biom15060903 · Cited by 40
Metadata
- Authors
- Deng, X., Liang, S., Cai, X., Huang, S., Cheng, Z., Shi, Y., Pang, M., Ma, P., & Lin, J.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2019-09-09
- Volume
- 19
- Issue
- 10
- Pages
- 6772-6780
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2972342221
- Cited by
- 319
- References
- 62
- FWCI
- 14.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- Deng, X., Liang, S., Cai, X., Huang, S., Cheng, Z., Shi, Y., Pang, M., Ma, P., & Lin, J. (2019). Yolk–Shell Structured Au Nanostar@Metal–Organic Framework for Synergistic Chemo-photothermal Therapy in the Second Near-Infrared Window. Nano Letters. https://doi.org/10.1021/acs.nanolett.9b01716
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